Radiology of severe acute respiratory syndrome (SARS): the emerging pathologic-radiologic correlates of an emerging disease.
Identifieur interne : 003D55 ( Main/Curation ); précédent : 003D54; suivant : 003D56Radiology of severe acute respiratory syndrome (SARS): the emerging pathologic-radiologic correlates of an emerging disease.
Auteurs : Loren Ketai [États-Unis] ; Narinder S. Paul ; Ka-Tak T. WongSource :
- Journal of thoracic imaging [ 0883-5993 ] ; 2006.
Descripteurs français
- KwdFr :
- Alvéoles pulmonaires (anatomopathologie), Alvéoles pulmonaires (imagerie diagnostique), Alvéoles pulmonaires (virologie), Convalescence, Flambées de maladies, Humains, Maladies transmissibles émergentes (anatomopathologie), Maladies transmissibles émergentes (imagerie diagnostique), Maladies transmissibles émergentes (transmission), Maladies transmissibles émergentes (virologie), Maladies transmissibles émergentes (épidémiologie), Muqueuse respiratoire (anatomopathologie), Muqueuse respiratoire (imagerie diagnostique), Muqueuse respiratoire (virologie), Radiographie thoracique, Syndrome respiratoire aigu sévère (anatomopathologie), Syndrome respiratoire aigu sévère (imagerie diagnostique), Syndrome respiratoire aigu sévère (transmission), Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie), Tomodensitométrie, Virus du SRAS.
- MESH :
- anatomopathologie : Alvéoles pulmonaires, Maladies transmissibles émergentes, Muqueuse respiratoire, Syndrome respiratoire aigu sévère.
- imagerie diagnostique : Alvéoles pulmonaires, Maladies transmissibles émergentes, Muqueuse respiratoire, Syndrome respiratoire aigu sévère.
- virologie : Alvéoles pulmonaires, Maladies transmissibles émergentes, Muqueuse respiratoire, Syndrome respiratoire aigu sévère.
- épidémiologie : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- Convalescence, Flambées de maladies, Humains, Radiographie thoracique, Tomodensitométrie, Virus du SRAS.
English descriptors
- KwdEn :
- Communicable Diseases, Emerging (diagnostic imaging), Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (pathology), Communicable Diseases, Emerging (transmission), Communicable Diseases, Emerging (virology), Convalescence, Disease Outbreaks, Humans, Pulmonary Alveoli (diagnostic imaging), Pulmonary Alveoli (pathology), Pulmonary Alveoli (virology), Radiography, Thoracic, Respiratory Mucosa (diagnostic imaging), Respiratory Mucosa (pathology), Respiratory Mucosa (virology), SARS Virus, Severe Acute Respiratory Syndrome (diagnostic imaging), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (pathology), Severe Acute Respiratory Syndrome (transmission), Severe Acute Respiratory Syndrome (virology), Tomography, X-Ray Computed.
- MESH :
- diagnostic imaging : Communicable Diseases, Emerging, Pulmonary Alveoli, Respiratory Mucosa, Severe Acute Respiratory Syndrome.
- epidemiology : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- pathology : Communicable Diseases, Emerging, Pulmonary Alveoli, Respiratory Mucosa, Severe Acute Respiratory Syndrome.
- transmission : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- virology : Communicable Diseases, Emerging, Pulmonary Alveoli, Respiratory Mucosa, Severe Acute Respiratory Syndrome.
- Convalescence, Disease Outbreaks, Humans, Radiography, Thoracic, SARS Virus, Tomography, X-Ray Computed.
Abstract
Severe acute respiratory distress syndrome (SARS) caused by SARS-associated coronavirus (SARS-CoV) is a systemic infection that clinically manifests as progressive pneumonia. During the initial phases of infection the virus causes pauci-inflammatory alveolar and interstitial edema that result in imaging abnormalities dominated by ground glass opacities (GGO). Severe SARS cases can develop radiologic and pathologic findings of diffuse alveolar damage. Although radiologic evidence of acute bronchiolitis is absent, SARS-CoV also infects ciliated airway epithelium, probably accounting for respiratory transmissibility of the virus. Radiologic recovery from SARS can be complete, but computed tomography images often show persistent GGO and reticular opacities, some of which reflect pathologic findings of fibrosis. Long-term follow-up imaging of survivors shows gradual decrease of GGO and reticulation with persistent air trapping in some patients. The latter is evidence of small airway disease that is not radiologically evident at the onset of the disease.
DOI: 10.1097/01.rti.0000213581.14225.f1
PubMed: 17110851
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pubmed:17110851Le document en format XML
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<front><div type="abstract" xml:lang="en">Severe acute respiratory distress syndrome (SARS) caused by SARS-associated coronavirus (SARS-CoV) is a systemic infection that clinically manifests as progressive pneumonia. During the initial phases of infection the virus causes pauci-inflammatory alveolar and interstitial edema that result in imaging abnormalities dominated by ground glass opacities (GGO). Severe SARS cases can develop radiologic and pathologic findings of diffuse alveolar damage. Although radiologic evidence of acute bronchiolitis is absent, SARS-CoV also infects ciliated airway epithelium, probably accounting for respiratory transmissibility of the virus. Radiologic recovery from SARS can be complete, but computed tomography images often show persistent GGO and reticular opacities, some of which reflect pathologic findings of fibrosis. Long-term follow-up imaging of survivors shows gradual decrease of GGO and reticulation with persistent air trapping in some patients. The latter is evidence of small airway disease that is not radiologically evident at the onset of the disease.</div>
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