Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?
Identifieur interne : 001F77 ( Main/Curation ); précédent : 001F76; suivant : 001F78Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?
Auteurs : Jasper F. W. Chan [Hong Kong] ; Kenneth S. M. Li [Hong Kong] ; Kelvin K. W. To [Hong Kong] ; Vincentc. C. Cheng [Hong Kong] ; HONGLIN CHEN [Hong Kong] ; Kwok-Yung Yuen [Hong Kong]Source :
- The Journal of infection [ 0163-4453 ] ; 2012.
Descripteurs français
- KwdFr :
- Animaux, Arabie saoudite, Chiroptera, Coronavirus (), Coronavirus (génétique), Coronavirus (isolement et purification), Humains, Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Organisation mondiale de la santé, Ovis, Pandémies, Phylogénie, Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie).
- MESH :
- génétique : Coronavirus.
- isolement et purification : Coronavirus.
- virologie : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- épidémiologie : Infections à coronavirus, Syndrome respiratoire aigu sévère.
- Pascal (Inist)
- Wicri :
- geographic : Arabie saoudite.
- topic : Homme.
English descriptors
- KwdEn :
- Animals, Chiroptera, Coronavirus (classification), Coronavirus (genetics), Coronavirus (isolation & purification), Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Human, Humans, Pandemics, Phylogeny, Saudi Arabia, Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (virology), Severe acute respiratory syndrome, Sheep, World Health Organization.
- MESH :
- geographic : Saudi Arabia.
- classification : Coronavirus.
- epidemiology : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- genetics : Coronavirus.
- isolation & purification : Coronavirus.
- virology : Coronavirus Infections, Severe Acute Respiratory Syndrome.
- Animals, Chiroptera, Humans, Pandemics, Phylogeny, Sheep, World Health Organization.
Abstract
Fouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named "human betacoronavirus 2c EMC/2012 (HCoV-EMC)" from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and HKU5 previously found in lesser bamboo bat and Japanese Pipistrelle bat of Hong Kong respectively. Another patient from Qatar with similar clinical presentation and positive RT-PCR test was reported in September 2012. We compare and contrast the clinical presentation, laboratory diagnosis and management of infection due to this novel coronavirus and that of SARS coronavirus despite the paucity of published information on the former. Since 70% of all emerging infectious pathogens came from animals, the emergence of this novel virus may represent another instance of interspecies jumping of betacoronavirus from animals to human similar to the group A coronavirus OC43 possibly from a bovine source in the 1890s and the group B SARS coronavirus in 2003 from bat to civet and human. Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy.
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W." last="Chan">Jasper F. W. Chan</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K. W." last="To">Kelvin K. W. To</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Vincentc C" sort="Cheng, Vincentc C" uniqKey="Cheng V" first="Vincentc. C." last="Cheng">Vincentc. C. Cheng</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Honglin Chen" sort="Honglin Chen" uniqKey="Honglin Chen" last="Honglin Chen">HONGLIN CHEN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">The Journal of infection</title><title level="j" type="abbreviated">J. infect.</title><idno type="ISSN">0163-4453</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The Journal of infection</title><title level="j" type="abbreviated">J. infect.</title><idno type="ISSN">0163-4453</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Chiroptera</term><term>Coronavirus (classification)</term><term>Coronavirus (genetics)</term><term>Coronavirus (isolation & purification)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (virology)</term><term>Human</term><term>Humans</term><term>Pandemics</term><term>Phylogeny</term><term>Saudi Arabia</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Severe acute respiratory syndrome</term><term>Sheep</term><term>World Health Organization</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Arabie saoudite</term><term>Chiroptera</term><term>Coronavirus ()</term><term>Coronavirus (génétique)</term><term>Coronavirus (isolement et purification)</term><term>Humains</term><term>Infections à coronavirus (virologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Organisation mondiale de la santé</term><term>Ovis</term><term>Pandémies</term><term>Phylogénie</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Saudi Arabia</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Chiroptera</term><term>Humans</term><term>Pandemics</term><term>Phylogeny</term><term>Sheep</term><term>World Health Organization</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Animaux</term><term>Arabie saoudite</term><term>Chiroptera</term><term>Coronavirus</term><term>Humains</term><term>Organisation mondiale de la santé</term><term>Ovis</term><term>Pandémies</term><term>Phylogénie</term><term>Syndrome respiratoire aigu sévère</term><term>Homme</term><term>Pandémie</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Arabie saoudite</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Fouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named "human betacoronavirus 2c EMC/2012 (HCoV-EMC)" from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and HKU5 previously found in lesser bamboo bat and Japanese Pipistrelle bat of Hong Kong respectively. Another patient from Qatar with similar clinical presentation and positive RT-PCR test was reported in September 2012. We compare and contrast the clinical presentation, laboratory diagnosis and management of infection due to this novel coronavirus and that of SARS coronavirus despite the paucity of published information on the former. Since 70% of all emerging infectious pathogens came from animals, the emergence of this novel virus may represent another instance of interspecies jumping of betacoronavirus from animals to human similar to the group A coronavirus OC43 possibly from a bovine source in the 1890s and the group B SARS coronavirus in 2003 from bat to civet and human. Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy.</div></front></TEI><double idat="0163-4453:2012:Chan J:is:the:discovery"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?</title><author><name sortKey="Chan, Jasper F W" sort="Chan, Jasper F W" uniqKey="Chan J" first="Jasper F. W." last="Chan">Jasper F. W. Chan</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K. W." last="To">Kelvin K. W. To</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Vincentc C" sort="Cheng, Vincentc C" uniqKey="Cheng V" first="Vincentc. C." last="Cheng">Vincentc. C. Cheng</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Honglin Chen" sort="Honglin Chen" uniqKey="Honglin Chen" last="Honglin Chen">HONGLIN CHEN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">13-0023614</idno><date when="2012">2012</date><idno type="stanalyst">PASCAL 13-0023614 INIST</idno><idno type="RBID">Pascal:13-0023614</idno><idno type="wicri:Area/PascalFrancis/Corpus">000032</idno><idno type="wicri:Area/PascalFrancis/Curation">000955</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000050</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000050</idno><idno type="wicri:doubleKey">0163-4453:2012:Chan J:is:the:discovery</idno><idno type="wicri:Area/Main/Merge">002001</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?</title><author><name sortKey="Chan, Jasper F W" sort="Chan, Jasper F W" uniqKey="Chan J" first="Jasper F. W." last="Chan">Jasper F. W. Chan</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K. W." last="To">Kelvin K. W. To</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Vincentc C" sort="Cheng, Vincentc C" uniqKey="Cheng V" first="Vincentc. C." last="Cheng">Vincentc. C. Cheng</name><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Honglin Chen" sort="Honglin Chen" uniqKey="Honglin Chen" last="Honglin Chen">HONGLIN CHEN</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><inist:fA14 i1="01"><s1>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>4 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</s1><s3>HKG</s3><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>6 aut.</sZ></inist:fA14><country>Hong Kong</country><wicri:noRegion>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">The Journal of infection</title><title level="j" type="abbreviated">J. infect.</title><idno type="ISSN">0163-4453</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">The Journal of infection</title><title level="j" type="abbreviated">J. infect.</title><idno type="ISSN">0163-4453</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Human</term><term>Severe acute respiratory syndrome</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Syndrome respiratoire aigu sévère</term><term>Homme</term><term>Pandémie</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Fouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named "human betacoronavirus 2c EMC/2012 (HCoV-EMC)" from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and HKU5 previously found in lesser bamboo bat and Japanese Pipistrelle bat of Hong Kong respectively. Another patient from Qatar with similar clinical presentation and positive RT-PCR test was reported in September 2012. We compare and contrast the clinical presentation, laboratory diagnosis and management of infection due to this novel coronavirus and that of SARS coronavirus despite the paucity of published information on the former. Since 70% of all emerging infectious pathogens came from animals, the emergence of this novel virus may represent another instance of interspecies jumping of betacoronavirus from animals to human similar to the group A coronavirus OC43 possibly from a bovine source in the 1890s and the group B SARS coronavirus in 2003 from bat to civet and human. Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy.</div></front></TEI></INIST><PMC><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?</title><author><name sortKey="Chan, Jasper F W" sort="Chan, Jasper F W" uniqKey="Chan J" first="Jasper F. W." last="Chan">Jasper F. W. Chan</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K. W." last="To">Kelvin K. W. To</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Vincent C C" sort="Cheng, Vincent C C" uniqKey="Cheng V" first="Vincent C. C." last="Cheng">Vincent C. C. Cheng</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23072791</idno><idno type="pmc">7112628</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7112628</idno><idno type="RBID">PMC:7112628</idno><idno type="doi">10.1016/j.jinf.2012.10.002</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001836</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001836</idno><idno type="wicri:Area/Pmc/Curation">001836</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001836</idno><idno type="wicri:Area/Pmc/Checkpoint">000A51</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000A51</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:23072791</idno><idno type="wicri:Area/PubMed/Corpus">001295</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001295</idno><idno type="wicri:Area/PubMed/Curation">001295</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001295</idno><idno type="wicri:Area/PubMed/Checkpoint">001331</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001331</idno><idno type="wicri:Area/Ncbi/Merge">002574</idno><idno type="wicri:Area/Ncbi/Curation">002574</idno><idno type="wicri:Area/Ncbi/Checkpoint">002574</idno><idno type="wicri:doubleKey">0163-4453:2012:Chan J:is:the:discovery</idno><idno type="wicri:Area/Main/Merge">001D19</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?</title><author><name sortKey="Chan, Jasper F W" sort="Chan, Jasper F W" uniqKey="Chan J" first="Jasper F. W." last="Chan">Jasper F. W. Chan</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Li, Kenneth S M" sort="Li, Kenneth S M" uniqKey="Li K" first="Kenneth S. M." last="Li">Kenneth S. M. Li</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="To, Kelvin K W" sort="To, Kelvin K W" uniqKey="To K" first="Kelvin K. W." last="To">Kelvin K. W. To</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Vincent C C" sort="Cheng, Vincent C C" uniqKey="Cheng V" first="Vincent C. C." last="Cheng">Vincent C. C. Cheng</name><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Honglin" sort="Chen, Honglin" uniqKey="Chen H" first="Honglin" last="Chen">Honglin Chen</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author><author><name sortKey="Yuen, Kwok Yung" sort="Yuen, Kwok Yung" uniqKey="Yuen K" first="Kwok-Yung" last="Yuen">Kwok-Yung Yuen</name><affiliation wicri:level="1"><nlm:aff id="aff1">State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2">Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Department of Microbiology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3">Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital, Hong Kong</nlm:aff><country xml:lang="fr">Hong Kong</country><wicri:regionArea>Research Centre of Infection and Immunology, The University of Hong Kong, Queen Mary Hospital</wicri:regionArea><wicri:noRegion>Queen Mary Hospital</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Journal of Infection</title><idno type="ISSN">0163-4453</idno><idno type="eISSN">1532-2742</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term><term>Chiroptera</term><term>Coronavirus (classification)</term><term>Coronavirus (genetics)</term><term>Coronavirus (isolation & purification)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (virology)</term><term>Humans</term><term>Pandemics</term><term>Phylogeny</term><term>Saudi Arabia</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Sheep</term><term>World Health Organization</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term><term>Arabie saoudite</term><term>Chiroptera</term><term>Coronavirus ()</term><term>Coronavirus (génétique)</term><term>Coronavirus (isolement et purification)</term><term>Humains</term><term>Infections à coronavirus (virologie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Organisation mondiale de la santé</term><term>Ovis</term><term>Pandémies</term><term>Phylogénie</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Saudi Arabia</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Animals</term><term>Chiroptera</term><term>Humans</term><term>Pandemics</term><term>Phylogeny</term><term>Sheep</term><term>World Health Organization</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Animaux</term><term>Arabie saoudite</term><term>Chiroptera</term><term>Coronavirus</term><term>Humains</term><term>Organisation mondiale de la santé</term><term>Ovis</term><term>Pandémies</term><term>Phylogénie</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Arabie saoudite</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p>Fouchier et al. reported the isolation and genome sequencing of a novel coronavirus tentatively named “human betacoronavirus 2c EMC/2012 (HCoV-EMC)” from a Saudi patient presenting with pneumonia and renal failure in June 2012. Genome sequencing showed that this virus belongs to the group C species of the genus betacoronavirus and phylogenetically related to the bat coronaviruses HKU4 and HKU5 previously found in lesser bamboo bat and Japanese Pipistrelle bat of Hong Kong respectively. Another patient from Qatar with similar clinical presentation and positive RT-PCR test was reported in September 2012. We compare and contrast the clinical presentation, laboratory diagnosis and management of infection due to this novel coronavirus and that of SARS coronavirus despite the paucity of published information on the former. Since 70% of all emerging infectious pathogens came from animals, the emergence of this novel virus may represent another instance of interspecies jumping of betacoronavirus from animals to human similar to the group A coronavirus OC43 possibly from a bovine source in the 1890s and the group B SARS coronavirus in 2003 from bat to civet and human. Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author><author><name sortKey="Schutten, M" uniqKey="Schutten M">M. Schutten</name></author><author><name sortKey="Van Amerongen, G" uniqKey="Van Amerongen G">G. van Amerongen</name></author><author><name sortKey="Van Doornum, G J" uniqKey="Van Doornum G">G.J. van Doornum</name></author><author><name sortKey="Van Den Hoogen, B G" uniqKey="Van Den Hoogen B">B.G. van den Hoogen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Osterhaus, A D" uniqKey="Osterhaus A">A.D. Osterhaus</name></author><author><name sortKey="Fouchier, R A" uniqKey="Fouchier R">R.A. Fouchier</name></author><author><name sortKey="Kuiken, T" uniqKey="Kuiken T">T. Kuiken</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Nicholls, J M" uniqKey="Nicholls J">J.M. Nicholls</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsang, K W" uniqKey="Tsang K">K.W. Tsang</name></author><author><name sortKey="Ho, P L" uniqKey="Ho P">P.L. Ho</name></author><author><name sortKey="Ooi, G C" uniqKey="Ooi G">G.C. Ooi</name></author><author><name sortKey="Yee, W K" uniqKey="Yee W">W.K. Yee</name></author><author><name sortKey="Wang, T" uniqKey="Wang T">T. Wang</name></author><author><name sortKey="Chan Yeung, M" uniqKey="Chan Yeung M">M. Chan-Yeung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Yam, L Y" uniqKey="Yam L">L.Y. Yam</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="World Health Organization Who" uniqKey="World Health Organization Who">World Health Organization (WHO)</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bermingham, A" uniqKey="Bermingham A">A. Bermingham</name></author><author><name sortKey="Chand, M A" uniqKey="Chand M">M.A. Chand</name></author><author><name sortKey="Brown, C S" uniqKey="Brown C">C.S. Brown</name></author><author><name sortKey="Aarons, E" uniqKey="Aarons E">E. Aarons</name></author><author><name sortKey="Tong, C" uniqKey="Tong C">C. Tong</name></author><author><name sortKey="Langrish, C" uniqKey="Langrish C">C. Langrish</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pebody, R G" uniqKey="Pebody R">R.G. Pebody</name></author><author><name sortKey="Chand, M A" uniqKey="Chand M">M.A. Chand</name></author><author><name sortKey="Thomas, H L" uniqKey="Thomas H">H.L. Thomas</name></author><author><name sortKey="Green, H K" uniqKey="Green H">H.K. Green</name></author><author><name sortKey="Boddington, N L" uniqKey="Boddington N">N.L. Boddington</name></author><author><name sortKey="Carvalho, C" uniqKey="Carvalho C">C. Carvalho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Promed Mail" uniqKey="Promed Mail">ProMED-mail</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="European Centre For Disease Prevention And Control Ecdc" uniqKey="European Centre For Disease Prevention And Control Ecdc">European Centre for Disease Prevention and Control (ECDC)</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="European Centres For Disease Control Ecdc" uniqKey="European Centres For Disease Control Ecdc">European Centres for Disease Control (ECDC)</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corman, V M" uniqKey="Corman V">V.M. Corman</name></author><author><name sortKey="Eckerle, I" uniqKey="Eckerle I">I. Eckerle</name></author><author><name sortKey="Bleicker, T" uniqKey="Bleicker T">T. Bleicker</name></author><author><name sortKey="Zaki, A" uniqKey="Zaki A">A. Zaki</name></author><author><name sortKey="Landt, O" uniqKey="Landt O">O. Landt</name></author><author><name sortKey="Eschbach Bludau, M" uniqKey="Eschbach Bludau M">M. Eschbach-Bludau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Health Protection Agency Hpa" uniqKey="Health Protection Agency Hpa">Health Protection Agency (HPA)</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Yip, C C" uniqKey="Yip C">C.C. Yip</name></author><author><name sortKey="Tse, H" uniqKey="Tse H">H. Tse</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Severance, E G" uniqKey="Severance E">E.G. Severance</name></author><author><name sortKey="Bossis, I" uniqKey="Bossis I">I. Bossis</name></author><author><name sortKey="Dickerson, F B" uniqKey="Dickerson F">F.B. Dickerson</name></author><author><name sortKey="Stallings, C R" uniqKey="Stallings C">C.R. Stallings</name></author><author><name sortKey="Origoni, A E" uniqKey="Origoni A">A.E. Origoni</name></author><author><name sortKey="Sullens, A" uniqKey="Sullens A">A. Sullens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Peiris, M" uniqKey="Peiris M">M. Peiris</name></author><author><name sortKey="Tsang, D N" uniqKey="Tsang D">D.N. Tsang</name></author><author><name sortKey="Que, T L" uniqKey="Que T">T.L. Que</name></author><author><name sortKey="Shortridge, K F" uniqKey="Shortridge K">K.F. Shortridge</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Yu, W C" uniqKey="Yu W">W.C. Yu</name></author><author><name sortKey="Leung, C W" uniqKey="Leung C">C.W. Leung</name></author><author><name sortKey="Cheung, C Y" uniqKey="Cheung C">C.Y. Cheung</name></author><author><name sortKey="Ng, W F" uniqKey="Ng W">W.F. Ng</name></author><author><name sortKey="Nicholls, J M" uniqKey="Nicholls J">J.M. Nicholls</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Cheung, C Y" uniqKey="Cheung C">C.Y. Cheung</name></author><author><name sortKey="Ellis, T M" uniqKey="Ellis T">T.M. Ellis</name></author><author><name sortKey="Lim, W" uniqKey="Lim W">W. Lim</name></author><author><name sortKey="Lipatov, A S" uniqKey="Lipatov A">A.S. Lipatov</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Xu, K M" uniqKey="Xu K">K.M. Xu</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Yu, K Z" uniqKey="Yu K">K.Z. Yu</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Smith, G J" uniqKey="Smith G">G.J. Smith</name></author><author><name sortKey="Xu, K M" uniqKey="Xu K">K.M. Xu</name></author><author><name sortKey="Duan, L" uniqKey="Duan L">L. Duan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, H" uniqKey="Chen H">H. Chen</name></author><author><name sortKey="Smith, G J" uniqKey="Smith G">G.J. Smith</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Wang, J" uniqKey="Wang J">J. Wang</name></author><author><name sortKey="Fan, X H" uniqKey="Fan X">X.H. Fan</name></author><author><name sortKey="Rayner, J M" uniqKey="Rayner J">J.M. Rayner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chen, X" uniqKey="Chen X">X. Chen</name></author><author><name sortKey="Smith, G J" uniqKey="Smith G">G.J. Smith</name></author><author><name sortKey="Zhou, B" uniqKey="Zhou B">B. Zhou</name></author><author><name sortKey="Qiu, C" uniqKey="Qiu C">C. Qiu</name></author><author><name sortKey="Wu, W L" uniqKey="Wu W">W.L. Wu</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhang, Z" uniqKey="Zhang Z">Z. Zhang</name></author><author><name sortKey="Zhang, J" uniqKey="Zhang J">J. Zhang</name></author><author><name sortKey="Huang, K" uniqKey="Huang K">K. Huang</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Beigel, J H" uniqKey="Beigel J">J.H. Beigel</name></author><author><name sortKey="Farrar, J" uniqKey="Farrar J">J. Farrar</name></author><author><name sortKey="Han, A M" uniqKey="Han A">A.M. Han</name></author><author><name sortKey="Hayden, F G" uniqKey="Hayden F">F.G. Hayden</name></author><author><name sortKey="Hyer, R" uniqKey="Hyer R">R. Hyer</name></author><author><name sortKey="De Jong, M D" uniqKey="De Jong M">M.D. de Jong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Li, K S" uniqKey="Li K">K.S. Li</name></author><author><name sortKey="Huang, Y" uniqKey="Huang Y">Y. Huang</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Wang, M" uniqKey="Wang M">M. Wang</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Xu, H" uniqKey="Xu H">H. Xu</name></author><author><name sortKey="Poon, R W" uniqKey="Poon R">R.W. Poon</name></author><author><name sortKey="Guo, R" uniqKey="Guo R">R. Guo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Duan, S M" uniqKey="Duan S">S.M. Duan</name></author><author><name sortKey="Zhao, X S" uniqKey="Zhao X">X.S. Zhao</name></author><author><name sortKey="Wen, R F" uniqKey="Wen R">R.F. Wen</name></author><author><name sortKey="Huang, J J" uniqKey="Huang J">J.J. Huang</name></author><author><name sortKey="Pi, G H" uniqKey="Pi G">G.H. Pi</name></author><author><name sortKey="Zhang, S X" uniqKey="Zhang S">S.X. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rabenau, H F" uniqKey="Rabenau H">H.F. Rabenau</name></author><author><name sortKey="Cinatl, J" uniqKey="Cinatl J">J. Cinatl</name></author><author><name sortKey="Morgenstern, B" uniqKey="Morgenstern B">B. Morgenstern</name></author><author><name sortKey="Bauer, G" uniqKey="Bauer G">G. Bauer</name></author><author><name sortKey="Preiser, W" uniqKey="Preiser W">W. Preiser</name></author><author><name sortKey="Doerr, H W" uniqKey="Doerr H">H.W. Doerr</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Tang, B S" uniqKey="Tang B">B.S. Tang</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Wong, M M" uniqKey="Wong M">M.M. Wong</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Chan, K S" uniqKey="Chan K">K.S. Chan</name></author><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Avendano, M" uniqKey="Avendano M">M. Avendano</name></author><author><name sortKey="Derkach, P" uniqKey="Derkach P">P. Derkach</name></author><author><name sortKey="Swan, S" uniqKey="Swan S">S. Swan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Booth, C M" uniqKey="Booth C">C.M. Booth</name></author><author><name sortKey="Matukas, L M" uniqKey="Matukas L">L.M. Matukas</name></author><author><name sortKey="Tomlinson, G A" uniqKey="Tomlinson G">G.A. Tomlinson</name></author><author><name sortKey="Rachlis, A R" uniqKey="Rachlis A">A.R. Rachlis</name></author><author><name sortKey="Rose, D B" uniqKey="Rose D">D.B. Rose</name></author><author><name sortKey="Dwosh, H A" uniqKey="Dwosh H">H.A. Dwosh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Ip, M" uniqKey="Ip M">M. Ip</name></author><author><name sortKey="Ng, K C" uniqKey="Ng K">K.C. Ng</name></author><author><name sortKey="Rickjason, C W" uniqKey="Rickjason C">C.W. Rickjason</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A. Wu</name></author><author><name sortKey="Lee, N" uniqKey="Lee N">N. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsu, L Y" uniqKey="Hsu L">L.Y. Hsu</name></author><author><name sortKey="Lee, C C" uniqKey="Lee C">C.C. Lee</name></author><author><name sortKey="Green, J A" uniqKey="Green J">J.A. Green</name></author><author><name sortKey="Ang, B" uniqKey="Ang B">B. Ang</name></author><author><name sortKey="Paton, N I" uniqKey="Paton N">N.I. Paton</name></author><author><name sortKey="Lee, L" uniqKey="Lee L">L. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, N" uniqKey="Lee N">N. Lee</name></author><author><name sortKey="Hui, D" uniqKey="Hui D">D. Hui</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A. Wu</name></author><author><name sortKey="Chan, P" uniqKey="Chan P">P. Chan</name></author><author><name sortKey="Cameron, P" uniqKey="Cameron P">P. Cameron</name></author><author><name sortKey="Joynt, G M" uniqKey="Joynt G">G.M. Joynt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rainer, T H" uniqKey="Rainer T">T.H. Rainer</name></author><author><name sortKey="Cameron, P A" uniqKey="Cameron P">P.A. Cameron</name></author><author><name sortKey="Smit, D" uniqKey="Smit D">D. Smit</name></author><author><name sortKey="Ong, K L" uniqKey="Ong K">K.L. Ong</name></author><author><name sortKey="Hung, A N" uniqKey="Hung A">A.N. Hung</name></author><author><name sortKey="Nin, D C" uniqKey="Nin D">D.C. Nin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Wong, S S" uniqKey="Wong S">S.S. Wong</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zhao, Z" uniqKey="Zhao Z">Z. Zhao</name></author><author><name sortKey="Zhang, F" uniqKey="Zhang F">F. Zhang</name></author><author><name sortKey="Xu, M" uniqKey="Xu M">M. Xu</name></author><author><name sortKey="Huang, K" uniqKey="Huang K">K. Huang</name></author><author><name sortKey="Zhong, W" uniqKey="Zhong W">W. Zhong</name></author><author><name sortKey="Cai, W" uniqKey="Cai W">W. Cai</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poutanen, S M" uniqKey="Poutanen S">S.M. Poutanen</name></author><author><name sortKey="Low, D E" uniqKey="Low D">D.E. Low</name></author><author><name sortKey="Henry, B" uniqKey="Henry B">B. Henry</name></author><author><name sortKey="Finkelstein, S" uniqKey="Finkelstein S">S. Finkelstein</name></author><author><name sortKey="Rose, D" uniqKey="Rose D">D. Rose</name></author><author><name sortKey="Green, K" uniqKey="Green K">K. Green</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grinblat, L" uniqKey="Grinblat L">L. Grinblat</name></author><author><name sortKey="Shulman, H" uniqKey="Shulman H">H. Shulman</name></author><author><name sortKey="Glickman, A" uniqKey="Glickman A">A. Glickman</name></author><author><name sortKey="Matukas, L" uniqKey="Matukas L">L. Matukas</name></author><author><name sortKey="Paul, N" uniqKey="Paul N">N. Paul</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hsieh, S C" uniqKey="Hsieh S">S.C. Hsieh</name></author><author><name sortKey="Chan, W P" uniqKey="Chan W">W.P. Chan</name></author><author><name sortKey="Chien, J C" uniqKey="Chien J">J.C. Chien</name></author><author><name sortKey="Lee, W S" uniqKey="Lee W">W.S. Lee</name></author><author><name sortKey="Yao, M S" uniqKey="Yao M">M.S. Yao</name></author><author><name sortKey="Choi, W M" uniqKey="Choi W">W.M. Choi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lai, E K" uniqKey="Lai E">E.K. Lai</name></author><author><name sortKey="Deif, H" uniqKey="Deif H">H. Deif</name></author><author><name sortKey="Lamere, E A" uniqKey="Lamere E">E.A. LaMere</name></author><author><name sortKey="Pham, D H" uniqKey="Pham D">D.H. Pham</name></author><author><name sortKey="Wolff, B" uniqKey="Wolff B">B. Wolff</name></author><author><name sortKey="Ward, S" uniqKey="Ward S">S. Ward</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, K T" uniqKey="Wong K">K.T. Wong</name></author><author><name sortKey="Antonio, G E" uniqKey="Antonio G">G.E. Antonio</name></author><author><name sortKey="Hui, D S" uniqKey="Hui D">D.S. Hui</name></author><author><name sortKey="Lee, N" uniqKey="Lee N">N. Lee</name></author><author><name sortKey="Yuen, E H" uniqKey="Yuen E">E.H. Yuen</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A. Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Leung, Y Y" uniqKey="Leung Y">Y.Y. Leung</name></author><author><name sortKey="Hui, J Y" uniqKey="Hui J">J.Y. Hui</name></author><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Chan, V L" uniqKey="Chan V">V.L. Chan</name></author><author><name sortKey="Leung, W S" uniqKey="Leung W">W.S. Leung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Franks, T J" uniqKey="Franks T">T.J. Franks</name></author><author><name sortKey="Chong, P Y" uniqKey="Chong P">P.Y. Chong</name></author><author><name sortKey="Chui, P" uniqKey="Chui P">P. Chui</name></author><author><name sortKey="Galvin, J R" uniqKey="Galvin J">J.R. Galvin</name></author><author><name sortKey="Lourens, R M" uniqKey="Lourens R">R.M. Lourens</name></author><author><name sortKey="Reid, A H" uniqKey="Reid A">A.H. Reid</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicholls, J M" uniqKey="Nicholls J">J.M. Nicholls</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Lee, K C" uniqKey="Lee K">K.C. Lee</name></author><author><name sortKey="Ng, W F" uniqKey="Ng W">W.F. Ng</name></author><author><name sortKey="Lai, S T" uniqKey="Lai S">S.T. Lai</name></author><author><name sortKey="Leung, C Y" uniqKey="Leung C">C.Y. Leung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hwang, D M" uniqKey="Hwang D">D.M. Hwang</name></author><author><name sortKey="Chamberlain, D W" uniqKey="Chamberlain D">D.W. Chamberlain</name></author><author><name sortKey="Poutanen, S M" uniqKey="Poutanen S">S.M. Poutanen</name></author><author><name sortKey="Low, D E" uniqKey="Low D">D.E. Low</name></author><author><name sortKey="Asa, S L" uniqKey="Asa S">S.L. Asa</name></author><author><name sortKey="Butany, J" uniqKey="Butany J">J. Butany</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Ding, Y" uniqKey="Ding Y">Y. Ding</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. Li</name></author><author><name sortKey="Yang, L" uniqKey="Yang L">L. Yang</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author><author><name sortKey="Kang, W" uniqKey="Kang W">W. Kang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ding, Y" uniqKey="Ding Y">Y. Ding</name></author><author><name sortKey="Wang, H" uniqKey="Wang H">H. Wang</name></author><author><name sortKey="Shen, H" uniqKey="Shen H">H. Shen</name></author><author><name sortKey="Li, Z" uniqKey="Li Z">Z. Li</name></author><author><name sortKey="Geng, J" uniqKey="Geng J">J. Geng</name></author><author><name sortKey="Han, H" uniqKey="Han H">H. Han</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, K H" uniqKey="Chu K">K.H. Chu</name></author><author><name sortKey="Tsang, W K" uniqKey="Tsang W">W.K. Tsang</name></author><author><name sortKey="Tang, C S" uniqKey="Tang C">C.S. Tang</name></author><author><name sortKey="Lam, M F" uniqKey="Lam M">M.F. Lam</name></author><author><name sortKey="Lai, F M" uniqKey="Lai F">F.M. Lai</name></author><author><name sortKey="To, K F" uniqKey="To K">K.F. To</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, V C" uniqKey="Wu V">V.C. Wu</name></author><author><name sortKey="Huang, J W" uniqKey="Huang J">J.W. Huang</name></author><author><name sortKey="Hsueh, P R" uniqKey="Hsueh P">P.R. Hsueh</name></author><author><name sortKey="Yang, Y F" uniqKey="Yang Y">Y.F. Yang</name></author><author><name sortKey="Tsai, H B" uniqKey="Tsai H">H.B. Tsai</name></author><author><name sortKey="Kan, W C" uniqKey="Kan W">W.C. Kan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Wu, A K" uniqKey="Wu A">A.K. Wu</name></author><author><name sortKey="Tang, B S" uniqKey="Tang B">B.S. Tang</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ziegler, A F" uniqKey="Ziegler A">A.F. Ziegler</name></author><author><name sortKey="Ladman, B S" uniqKey="Ladman B">B.S. Ladman</name></author><author><name sortKey="Dunn, P A" uniqKey="Dunn P">P.A. Dunn</name></author><author><name sortKey="Schneider, A" uniqKey="Schneider A">A. Schneider</name></author><author><name sortKey="Davison, S" uniqKey="Davison S">S. Davison</name></author><author><name sortKey="Miller, P G" uniqKey="Miller P">P.G. Miller</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chau, T N" uniqKey="Chau T">T.N. Chau</name></author><author><name sortKey="Lee, K C" uniqKey="Lee K">K.C. Lee</name></author><author><name sortKey="Yao, H" uniqKey="Yao H">H. Yao</name></author><author><name sortKey="Tsang, T Y" uniqKey="Tsang T">T.Y. Tsang</name></author><author><name sortKey="Chow, T C" uniqKey="Chow T">T.C. Chow</name></author><author><name sortKey="Yeung, Y C" uniqKey="Yeung Y">Y.C. Yeung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, K K" uniqKey="Lau K">K.K. Lau</name></author><author><name sortKey="Yu, W C" uniqKey="Yu W">W.C. Yu</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Lau, S T" uniqKey="Lau S">S.T. Lau</name></author><author><name sortKey="Sheng, B" uniqKey="Sheng B">B. Sheng</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, S S" uniqKey="Li S">S.S. Li</name></author><author><name sortKey="Cheng, C W" uniqKey="Cheng C">C.W. Cheng</name></author><author><name sortKey="Fu, C L" uniqKey="Fu C">C.L. Fu</name></author><author><name sortKey="Chan, Y H" uniqKey="Chan Y">Y.H. Chan</name></author><author><name sortKey="Lee, M P" uniqKey="Lee M">M.P. Lee</name></author><author><name sortKey="Chan, J W" uniqKey="Chan J">J.W. Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ng, K H" uniqKey="Ng K">K.H. Ng</name></author><author><name sortKey="Wu, A K" uniqKey="Wu A">A.K. Wu</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Tang, B S" uniqKey="Tang B">B.S. Tang</name></author><author><name sortKey="Chan, C Y" uniqKey="Chan C">C.Y. Chan</name></author><author><name sortKey="Yung, C Y" uniqKey="Yung C">C.Y. Yung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsai, L K" uniqKey="Tsai L">L.K. Tsai</name></author><author><name sortKey="Hsieh, S T" uniqKey="Hsieh S">S.T. Hsieh</name></author><author><name sortKey="Chao, C C" uniqKey="Chao C">C.C. Chao</name></author><author><name sortKey="Chen, Y C" uniqKey="Chen Y">Y.C. Chen</name></author><author><name sortKey="Lin, Y H" uniqKey="Lin Y">Y.H. Lin</name></author><author><name sortKey="Chang, S C" uniqKey="Chang S">S.C. Chang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, J L" uniqKey="Wang J">J.L. Wang</name></author><author><name sortKey="Wang, J T" uniqKey="Wang J">J.T. Wang</name></author><author><name sortKey="Yu, C J" uniqKey="Yu C">C.J. Yu</name></author><author><name sortKey="Chen, Y C" uniqKey="Chen Y">Y.C. Chen</name></author><author><name sortKey="Hsueh, P R" uniqKey="Hsueh P">P.R. Hsueh</name></author><author><name sortKey="Hsiao, C H" uniqKey="Hsiao C">C.H. Hsiao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, E B" uniqKey="Wu E">E.B. Wu</name></author><author><name sortKey="Sung, J J" uniqKey="Sung J">J.J. Sung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="World Health Organization" uniqKey="World Health Organization">World Health Organization</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Health Protection Agency Hpa" uniqKey="Health Protection Agency Hpa">Health protection Agency (HPA)</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chow, K Y" uniqKey="Chow K">K.Y. Chow</name></author><author><name sortKey="Lee, C E" uniqKey="Lee C">C.E. Lee</name></author><author><name sortKey="Ling, M L" uniqKey="Ling M">M.L. Ling</name></author><author><name sortKey="Heng, D M" uniqKey="Heng D">D.M. Heng</name></author><author><name sortKey="Yap, S G" uniqKey="Yap S">S.G. Yap</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, K C" uniqKey="Wong K">K.C. Wong</name></author><author><name sortKey="Leung, K S" uniqKey="Leung K">K.S. Leung</name></author><author><name sortKey="Hui, M" uniqKey="Hui M">M. Hui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bitnun, A" uniqKey="Bitnun A">A. Bitnun</name></author><author><name sortKey="Allen, U" uniqKey="Allen U">U. Allen</name></author><author><name sortKey="Heurter, H" uniqKey="Heurter H">H. Heurter</name></author><author><name sortKey="King, S M" uniqKey="King S">S.M. King</name></author><author><name sortKey="Opavsky, M A" uniqKey="Opavsky M">M.A. Opavsky</name></author><author><name sortKey="Ford Jones, E L" uniqKey="Ford Jones E">E.L. Ford-Jones</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hon, K L" uniqKey="Hon K">K.L. Hon</name></author><author><name sortKey="Leung, C W" uniqKey="Leung C">C.W. Leung</name></author><author><name sortKey="Cheng, W T" uniqKey="Cheng W">W.T. Cheng</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Chu, W C" uniqKey="Chu W">W.C. Chu</name></author><author><name sortKey="Kwan, Y W" uniqKey="Kwan Y">Y.W. Kwan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kwan, M Y" uniqKey="Kwan M">M.Y. Kwan</name></author><author><name sortKey="Chan, W M" uniqKey="Chan W">W.M. Chan</name></author><author><name sortKey="Ko, P W" uniqKey="Ko P">P.W. Ko</name></author><author><name sortKey="Leung, C W" uniqKey="Leung C">C.W. Leung</name></author><author><name sortKey="Chiu, M C" uniqKey="Chiu M">M.C. Chiu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Che, X Y" uniqKey="Che X">X.Y. Che</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Tam, J S" uniqKey="Tam J">J.S. Tam</name></author><author><name sortKey="Lam, C W" uniqKey="Lam C">C.W. Lam</name></author><author><name sortKey="Chan, E" uniqKey="Chan E">E. Chan</name></author><author><name sortKey="Wu, A" uniqKey="Wu A">A. Wu</name></author><author><name sortKey="Li, C K" uniqKey="Li C">C.K. Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Kong, J" uniqKey="Kong J">J. Kong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Che, X Y" uniqKey="Che X">X.Y. Che</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Woo, G K" uniqKey="Woo G">G.K. Woo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Wong, O K" uniqKey="Wong O">O.K. Wong</name></author><author><name sortKey="Yam, W C" uniqKey="Yam W">W.C. Yam</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Wong, O K" uniqKey="Wong O">O.K. Wong</name></author><author><name sortKey="Cheung, T K" uniqKey="Cheung T">T.K. Cheung</name></author><author><name sortKey="Ng, I" uniqKey="Ng I">I. Ng</name></author><author><name sortKey="Zheng, B" uniqKey="Zheng B">B. Zheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Wong, B W" uniqKey="Wong B">B.W. Wong</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Leung, C S" uniqKey="Leung C">C.S. Leung</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, P K" uniqKey="Cheng P">P.K. Cheng</name></author><author><name sortKey="Wong, D A" uniqKey="Wong D">D.A. Wong</name></author><author><name sortKey="Tong, L K" uniqKey="Tong L">L.K. Tong</name></author><author><name sortKey="Ip, S M" uniqKey="Ip S">S.M. Ip</name></author><author><name sortKey="Lo, A C" uniqKey="Lo A">A.C. Lo</name></author><author><name sortKey="Lau, C S" uniqKey="Lau C">C.S. Lau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hui, R K" uniqKey="Hui R">R.K. Hui</name></author><author><name sortKey="Zeng, F" uniqKey="Zeng F">F. Zeng</name></author><author><name sortKey="Chan, C M" uniqKey="Chan C">C.M. Chan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Peiris, J S" uniqKey="Peiris J">J.S. Peiris</name></author><author><name sortKey="Leung, F C" uniqKey="Leung F">F.C. Leung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wang, W K" uniqKey="Wang W">W.K. Wang</name></author><author><name sortKey="Chen, S Y" uniqKey="Chen S">S.Y. Chen</name></author><author><name sortKey="Liu, I J" uniqKey="Liu I">I.J. Liu</name></author><author><name sortKey="Chen, Y C" uniqKey="Chen Y">Y.C. Chen</name></author><author><name sortKey="Chen, H L" uniqKey="Chen H">H.L. Chen</name></author><author><name sortKey="Yang, C F" uniqKey="Yang C">C.F. Yang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, H S" uniqKey="Wu H">H.S. Wu</name></author><author><name sortKey="Chiu, S C" uniqKey="Chiu S">S.C. Chiu</name></author><author><name sortKey="Tseng, T C" uniqKey="Tseng T">T.C. Tseng</name></author><author><name sortKey="Lin, S F" uniqKey="Lin S">S.F. Lin</name></author><author><name sortKey="Lin, J H" uniqKey="Lin J">J.H. Lin</name></author><author><name sortKey="Hsu, Y H" uniqKey="Hsu Y">Y.H. Hsu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yam, W C" uniqKey="Yam W">W.C. Yam</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author><author><name sortKey="Poon, L L" uniqKey="Poon L">L.L. Poon</name></author><author><name sortKey="Guan, Y" uniqKey="Guan Y">Y. Guan</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Seto, W H" uniqKey="Seto W">W.H. Seto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Risku, M" uniqKey="Risku M">M. Risku</name></author><author><name sortKey="Lappalainen, S" uniqKey="Lappalainen S">S. Lappalainen</name></author><author><name sortKey="R S Nen, S" uniqKey="R S Nen S">S. Räsänen</name></author><author><name sortKey="Vesikari, T" uniqKey="Vesikari T">T. Vesikari</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grant, P R" uniqKey="Grant P">P.R. Grant</name></author><author><name sortKey="Garson, J A" uniqKey="Garson J">J.A. Garson</name></author><author><name sortKey="Tedder, R S" uniqKey="Tedder R">R.S. Tedder</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Tam, J S" uniqKey="Tam J">J.S. Tam</name></author><author><name sortKey="Sung, J J" uniqKey="Sung J">J.J. Sung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Wong, B H" uniqKey="Wong B">B.H. Wong</name></author><author><name sortKey="Tsoi, H W" uniqKey="Tsoi H">H.W. Tsoi</name></author><author><name sortKey="Fung, A M" uniqKey="Fung A">A.M. Fung</name></author><author><name sortKey="Chan, K H" uniqKey="Chan K">K.H. Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Che, X Y" uniqKey="Che X">X.Y. Che</name></author><author><name sortKey="Hao, W" uniqKey="Hao W">W. Hao</name></author><author><name sortKey="Wang, Y" uniqKey="Wang Y">Y. Wang</name></author><author><name sortKey="Di, B" uniqKey="Di B">B. Di</name></author><author><name sortKey="Yin, K" uniqKey="Yin K">K. Yin</name></author><author><name sortKey="Xu, Y C" uniqKey="Xu Y">Y.C. Xu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Che, X Y" uniqKey="Che X">X.Y. Che</name></author><author><name sortKey="Qiu, L W" uniqKey="Qiu L">L.W. Qiu</name></author><author><name sortKey="Pan, Y X" uniqKey="Pan Y">Y.X. Pan</name></author><author><name sortKey="Wen, K" uniqKey="Wen K">K. Wen</name></author><author><name sortKey="Hao, W" uniqKey="Hao W">W. Hao</name></author><author><name sortKey="Zhang, L Y" uniqKey="Zhang L">L.Y. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leroy, E M" uniqKey="Leroy E">E.M. Leroy</name></author><author><name sortKey="Kumulungui, B" uniqKey="Kumulungui B">B. Kumulungui</name></author><author><name sortKey="Pourrut, X" uniqKey="Pourrut X">X. Pourrut</name></author><author><name sortKey="Rouquet, P" uniqKey="Rouquet P">P. Rouquet</name></author><author><name sortKey="Hassanin, A" uniqKey="Hassanin A">A. Hassanin</name></author><author><name sortKey="Yaba, P" uniqKey="Yaba P">P. Yaba</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, S" uniqKey="Wong S">S. Wong</name></author><author><name sortKey="Lau, S" uniqKey="Lau S">S. Lau</name></author><author><name sortKey="Woo, P" uniqKey="Woo P">P. Woo</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author><author><name sortKey="Lau, S K" uniqKey="Lau S">S.K. Lau</name></author><author><name sortKey="Woo, P C" uniqKey="Woo P">P.C. Woo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seto, W H" uniqKey="Seto W">W.H. Seto</name></author><author><name sortKey="Tsang, D" uniqKey="Tsang D">D. Tsang</name></author><author><name sortKey="Yung, R W" uniqKey="Yung R">R.W. Yung</name></author><author><name sortKey="Ching, T Y" uniqKey="Ching T">T.Y. Ching</name></author><author><name sortKey="Ng, T K" uniqKey="Ng T">T.K. Ng</name></author><author><name sortKey="Ho, M" uniqKey="Ho M">M. Ho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Christian, M D" uniqKey="Christian M">M.D. Christian</name></author><author><name sortKey="Loutfy, M" uniqKey="Loutfy M">M. Loutfy</name></author><author><name sortKey="Mcdonald, L C" uniqKey="Mcdonald L">L.C. McDonald</name></author><author><name sortKey="Martinez, K F" uniqKey="Martinez K">K.F. Martinez</name></author><author><name sortKey="Ofner, M" uniqKey="Ofner M">M. Ofner</name></author><author><name sortKey="Wong, T" uniqKey="Wong T">T. Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Varia, M" uniqKey="Varia M">M. Varia</name></author><author><name sortKey="Wilson, S" uniqKey="Wilson S">S. Wilson</name></author><author><name sortKey="Sarwal, S" uniqKey="Sarwal S">S. Sarwal</name></author><author><name sortKey="Mcgeer, A" uniqKey="Mcgeer A">A. McGeer</name></author><author><name sortKey="Gournis, E" uniqKey="Gournis E">E. Gournis</name></author><author><name sortKey="Galanis, E" uniqKey="Galanis E">E. Galanis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Hung, I F" uniqKey="Hung I">I.F. Hung</name></author><author><name sortKey="Chan, K S" uniqKey="Chan K">K.S. Chan</name></author><author><name sortKey="Tang, B S" uniqKey="Tang B">B.S. Tang</name></author><author><name sortKey="Tsang, T H" uniqKey="Tsang T">T.H. Tsang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yu, I T" uniqKey="Yu I">I.T. Yu</name></author><author><name sortKey="Li, Y" uniqKey="Li Y">Y. Li</name></author><author><name sortKey="Wong, T W" uniqKey="Wong T">T.W. Wong</name></author><author><name sortKey="Tam, W" uniqKey="Tam W">W. Tam</name></author><author><name sortKey="Chan, A T" uniqKey="Chan A">A.T. Chan</name></author><author><name sortKey="Lee, J H" uniqKey="Lee J">J.H. Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Centers For Disease Control And Prevention Cdc" uniqKey="Centers For Disease Control And Prevention Cdc">Centers for Disease Control and Prevention (CDC)</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lessler, J" uniqKey="Lessler J">J. Lessler</name></author><author><name sortKey="Reich, N G" uniqKey="Reich N">N.G. Reich</name></author><author><name sortKey="Brookmeyer, R" uniqKey="Brookmeyer R">R. Brookmeyer</name></author><author><name sortKey="Perl, T M" uniqKey="Perl T">T.M. Perl</name></author><author><name sortKey="Nelson, K E" uniqKey="Nelson K">K.E. Nelson</name></author><author><name sortKey="Cummings, D A" uniqKey="Cummings D">D.A. Cummings</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chan, W M" uniqKey="Chan W">W.M. Chan</name></author><author><name sortKey="Kwan, Y W" uniqKey="Kwan Y">Y.W. Kwan</name></author><author><name sortKey="Wan, H S" uniqKey="Wan H">H.S. Wan</name></author><author><name sortKey="Leung, C W" uniqKey="Leung C">C.W. Leung</name></author><author><name sortKey="Chiu, M C" uniqKey="Chiu M">M.C. Chiu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, V C" uniqKey="Cheng V">V.C. Cheng</name></author><author><name sortKey="Tang, B S" uniqKey="Tang B">B.S. Tang</name></author><author><name sortKey="Wu, A K" uniqKey="Wu A">A.K. Wu</name></author><author><name sortKey="Chu, C M" uniqKey="Chu C">C.M. Chu</name></author><author><name sortKey="Yuen, K Y" uniqKey="Yuen K">K.Y. Yuen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Peek, G J" uniqKey="Peek G">G.J. Peek</name></author><author><name sortKey="Moore, H M" uniqKey="Moore H">H.M. Moore</name></author><author><name sortKey="Moore, N" uniqKey="Moore N">N. Moore</name></author><author><name sortKey="Sosnowski, A W" uniqKey="Sosnowski A">A.W. Sosnowski</name></author><author><name sortKey="Firmin, R K" uniqKey="Firmin R">R.K. Firmin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lewandowski, K" uniqKey="Lewandowski K">K. Lewandowski</name></author><author><name sortKey="Rossaint, R" uniqKey="Rossaint R">R. Rossaint</name></author><author><name sortKey="Pappert, D" uniqKey="Pappert D">D. Pappert</name></author><author><name sortKey="Gerlach, H" uniqKey="Gerlach H">H. Gerlach</name></author><author><name sortKey="Slama, K J" uniqKey="Slama K">K.J. Slama</name></author><author><name sortKey="Weidemann, H" uniqKey="Weidemann H">H. Weidemann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hemmila, M R" uniqKey="Hemmila M">M.R. Hemmila</name></author><author><name sortKey="Rowe, S A" uniqKey="Rowe S">S.A. Rowe</name></author><author><name sortKey="Boules, T N" uniqKey="Boules T">T.N. Boules</name></author><author><name sortKey="Miskulin, J" uniqKey="Miskulin J">J. Miskulin</name></author><author><name sortKey="Mcgillicuddy, J W" uniqKey="Mcgillicuddy J">J.W. McGillicuddy</name></author><author><name sortKey="Schuerer, D J" uniqKey="Schuerer D">D.J. Schuerer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brogan, T V" uniqKey="Brogan T">T.V. Brogan</name></author><author><name sortKey="Thiagarajan, R R" uniqKey="Thiagarajan R">R.R. Thiagarajan</name></author><author><name sortKey="Rycus, P T" uniqKey="Rycus P">P.T. Rycus</name></author><author><name sortKey="Bartlett, R H" uniqKey="Bartlett R">R.H. Bartlett</name></author><author><name sortKey="Bratton, S L" uniqKey="Bratton S">S.L. Bratton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="So, L K" uniqKey="So L">L.K. So</name></author><author><name sortKey="Lau, A C" uniqKey="Lau A">A.C. Lau</name></author><author><name sortKey="Yam, L Y" uniqKey="Yam L">L.Y. Yam</name></author><author><name sortKey="Cheung, T M" uniqKey="Cheung T">T.M. Cheung</name></author><author><name sortKey="Poon, E" uniqKey="Poon E">E. Poon</name></author><author><name sortKey="Yung, R W" uniqKey="Yung R">R.W. Yung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, V W" uniqKey="Wong V">V.W. Wong</name></author><author><name sortKey="Dai, D" uniqKey="Dai D">D. Dai</name></author><author><name sortKey="Wu, A K" uniqKey="Wu A">A.K. Wu</name></author><author><name sortKey="Sung, J J" uniqKey="Sung J">J.J. Sung</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yeh, K M" uniqKey="Yeh K">K.M. Yeh</name></author><author><name sortKey="Chiueh, T S" uniqKey="Chiueh T">T.S. Chiueh</name></author><author><name sortKey="Siu, L K" uniqKey="Siu L">L.K. Siu</name></author><author><name sortKey="Lin, J C" uniqKey="Lin J">J.C. Lin</name></author><author><name sortKey="Chan, P K" uniqKey="Chan P">P.K. Chan</name></author><author><name sortKey="Peng, M Y" uniqKey="Peng M">M.Y. Peng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cheng, Y" uniqKey="Cheng Y">Y. Cheng</name></author><author><name sortKey="Wong, R" uniqKey="Wong R">R. Wong</name></author><author><name sortKey="Soo, Y O" uniqKey="Soo Y">Y.O. Soo</name></author><author><name sortKey="Wong, W S" uniqKey="Wong W">W.S. Wong</name></author><author><name sortKey="Lee, C K" uniqKey="Lee C">C.K. Lee</name></author><author><name sortKey="Ng, M H" uniqKey="Ng M">M.H. Ng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ho, J C" uniqKey="Ho J">J.C. Ho</name></author><author><name sortKey="Wu, A Y" uniqKey="Wu A">A.Y. Wu</name></author><author><name sortKey="Lam, B" uniqKey="Lam B">B. Lam</name></author><author><name sortKey="Ooi, G C" uniqKey="Ooi G">G.C. Ooi</name></author><author><name sortKey="Khong, P L" uniqKey="Khong P">P.L. Khong</name></author><author><name sortKey="Ho, P L" uniqKey="Ho P">P.L. Ho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="World Health Organization Who" uniqKey="World Health Organization Who">World Health Organization (WHO)</name></author></analytic></biblStruct></listBibl></div1></back></TEI></PMC></double></record>Pour manipuler ce document sous Unix (Dilib)
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