Blood group A and D negativity are associated with symptomatic West Nile virus infection
Identifieur interne : 001183 ( Main/Curation ); précédent : 001182; suivant : 001184Blood group A and D negativity are associated with symptomatic West Nile virus infection
Auteurs : Zhanna Kaidarova [États-Unis] ; Marjorie D. Bravo ; Hany T. Kamel ; Brian S. Custer [États-Unis] ; Michael P. Busch [États-Unis] ; Marion C. Lanteri [États-Unis]Source :
- Transfusion [ 0041-1132 ] ; 2016-07.
Abstract
BACKGROUND: West Nile virus (WNV) infection is mostly asymptomatic (AS) but 20% of subjects report WNV fever and 1% of patients experience neurologic diseases with higher rates in elderly and immunosuppressed persons. With no treatment and no vaccine to prevent the development of symptomatic (S) infections, it is essential to understand prognostic factors influencing S disease outcome. Host genetic background has been linked to the development of WNV neuroinvasive disease. This study investigates the association between the ABO and D blood group status and WNV disease outcome. STUDY DESIGN AND METHODS: The distribution of blood groups was investigated within a cohort of 374 WNV+ blood donors including 244 AS and 130 S WNV+ blood donors. Logistic regression analyses were used to examine associations between A, B, O, and D blood groups and WNV clinical disease outcome. RESULTS: S WNV+ donors exhibited increased frequencies of blood group A (S 47.6%, AS 36.8%, p = 0.04; odds ratio [OR], 1.56; 95% confidence interval [CI], 1.01‐2.40) and D– individuals (S 21.5%, AS 13.1%, p = 0.03; OR, 1.82; 95% CI, 1.04‐3.18). CONCLUSION: The findings suggest a genetic susceptibility placing blood group A and D– individuals at risk for the development of S disease outcome after WNV infection.
Url:
DOI: 10.1111/trf.13622
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001644
- to stream Istex, to step Curation: Pour aller vers cette notice dans l'étape Curation :001644
- to stream Istex, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000089
- to stream Main, to step Merge: Pour aller vers cette notice dans l'étape Curation :001185
Links to Exploration step
ISTEX:CA996A5B52C523438C8FA859719EB832F58763BCCuration
No country items
Marjorie D. Bravo<affiliation><wicri:noCountry code="subField">Scottsdale</wicri:noCountry>
</affiliation>
<affiliation><wicri:noCountry code="subField">Scottsdale</wicri:noCountry>
</affiliation>
<affiliation><wicri:noCountry code="no comma">E-mail: mlanteri@bloodsystems.org</wicri:noCountry>
</affiliation>
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Blood group A and D negativity are associated with symptomatic West Nile virus infection</title>
<author><name sortKey="Kaidarova, Zhanna" sort="Kaidarova, Zhanna" uniqKey="Kaidarova Z" first="Zhanna" last="Kaidarova">Zhanna Kaidarova</name>
</author>
<author><name sortKey="Bravo, Marjorie D" sort="Bravo, Marjorie D" uniqKey="Bravo M" first="Marjorie D." last="Bravo">Marjorie D. Bravo</name>
</author>
<author><name sortKey="Kamel, Hany T" sort="Kamel, Hany T" uniqKey="Kamel H" first="Hany T." last="Kamel">Hany T. Kamel</name>
</author>
<author><name sortKey="Custer, Brian S" sort="Custer, Brian S" uniqKey="Custer B" first="Brian S." last="Custer">Brian S. Custer</name>
</author>
<author><name sortKey="Busch, Michael P" sort="Busch, Michael P" uniqKey="Busch M" first="Michael P." last="Busch">Michael P. Busch</name>
</author>
<author><name sortKey="Lanteri, Marion C" sort="Lanteri, Marion C" uniqKey="Lanteri M" first="Marion C." last="Lanteri">Marion C. Lanteri</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:CA996A5B52C523438C8FA859719EB832F58763BC</idno>
<date when="2016" year="2016">2016</date>
<idno type="doi">10.1111/trf.13622</idno>
<idno type="url">https://api.istex.fr/ark:/67375/WNG-F3VHS0X8-M/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">001644</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001644</idno>
<idno type="wicri:Area/Istex/Curation">001644</idno>
<idno type="wicri:Area/Istex/Checkpoint">000089</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000089</idno>
<idno type="wicri:doubleKey">0041-1132:2016:Kaidarova Z:blood:group:a</idno>
<idno type="wicri:Area/Main/Merge">001185</idno>
<idno type="wicri:Area/Main/Curation">001183</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Blood group A and D negativity are associated with symptomatic West Nile virus infection</title>
<author><name sortKey="Kaidarova, Zhanna" sort="Kaidarova, Zhanna" uniqKey="Kaidarova Z" first="Zhanna" last="Kaidarova">Zhanna Kaidarova</name>
<affiliation wicri:level="3"><country>États-Unis</country>
<placeName><settlement type="city">San Francisco</settlement>
<region type="state">Californie</region>
</placeName>
<wicri:orgArea>Blood Systems Research Institute, California</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Bravo, Marjorie D" sort="Bravo, Marjorie D" uniqKey="Bravo M" first="Marjorie D." last="Bravo">Marjorie D. Bravo</name>
<affiliation><wicri:noCountry code="subField">Scottsdale</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kamel, Hany T" sort="Kamel, Hany T" uniqKey="Kamel H" first="Hany T." last="Kamel">Hany T. Kamel</name>
<affiliation><wicri:noCountry code="subField">Scottsdale</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Custer, Brian S" sort="Custer, Brian S" uniqKey="Custer B" first="Brian S." last="Custer">Brian S. Custer</name>
<affiliation wicri:level="2"><country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Blood Systems Research Institute, San Francisco</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><country>États-Unis</country>
<placeName><settlement type="city">San Francisco</settlement>
<region type="state">Californie</region>
</placeName>
<wicri:orgArea>Department of Laboratory Medicine, University of California at San Francisco, California</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Busch, Michael P" sort="Busch, Michael P" uniqKey="Busch M" first="Michael P." last="Busch">Michael P. Busch</name>
<affiliation wicri:level="2"><country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Blood Systems Research Institute, San Francisco</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><country>États-Unis</country>
<placeName><settlement type="city">San Francisco</settlement>
<region type="state">Californie</region>
</placeName>
<wicri:orgArea>Department of Laboratory Medicine, University of California at San Francisco, California</wicri:orgArea>
</affiliation>
</author>
<author><name sortKey="Lanteri, Marion C" sort="Lanteri, Marion C" uniqKey="Lanteri M" first="Marion C." last="Lanteri">Marion C. Lanteri</name>
<affiliation wicri:level="2"><country>États-Unis</country>
<placeName><region type="state">Californie</region>
</placeName>
<wicri:cityArea>Blood Systems Research Institute, San Francisco</wicri:cityArea>
</affiliation>
<affiliation wicri:level="3"><country>États-Unis</country>
<placeName><settlement type="city">San Francisco</settlement>
<region type="state">Californie</region>
</placeName>
<wicri:orgArea>Department of Laboratory Medicine, University of California at San Francisco, California</wicri:orgArea>
</affiliation>
<affiliation><wicri:noCountry code="no comma">E-mail: mlanteri@bloodsystems.org</wicri:noCountry>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Transfusion</title>
<title level="j" type="alt">TRANSFUSION</title>
<idno type="ISSN">0041-1132</idno>
<idno type="eISSN">1537-2995</idno>
<imprint><biblScope unit="vol">56</biblScope>
<biblScope unit="issue">7</biblScope>
<biblScope unit="page" from="1699">1699</biblScope>
<biblScope unit="page" to="1706">1706</biblScope>
<biblScope unit="page-count">8</biblScope>
<date type="published" when="2016-07">2016-07</date>
</imprint>
<idno type="ISSN">0041-1132</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">0041-1132</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract">BACKGROUND: West Nile virus (WNV) infection is mostly asymptomatic (AS) but 20% of subjects report WNV fever and 1% of patients experience neurologic diseases with higher rates in elderly and immunosuppressed persons. With no treatment and no vaccine to prevent the development of symptomatic (S) infections, it is essential to understand prognostic factors influencing S disease outcome. Host genetic background has been linked to the development of WNV neuroinvasive disease. This study investigates the association between the ABO and D blood group status and WNV disease outcome. STUDY DESIGN AND METHODS: The distribution of blood groups was investigated within a cohort of 374 WNV+ blood donors including 244 AS and 130 S WNV+ blood donors. Logistic regression analyses were used to examine associations between A, B, O, and D blood groups and WNV clinical disease outcome. RESULTS: S WNV+ donors exhibited increased frequencies of blood group A (S 47.6%, AS 36.8%, p = 0.04; odds ratio [OR], 1.56; 95% confidence interval [CI], 1.01‐2.40) and D– individuals (S 21.5%, AS 13.1%, p = 0.03; OR, 1.82; 95% CI, 1.04‐3.18). CONCLUSION: The findings suggest a genetic susceptibility placing blood group A and D– individuals at risk for the development of S disease outcome after WNV infection.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001183 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Curation/biblio.hfd -nk 001183 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Main |étape= Curation |type= RBID |clé= ISTEX:CA996A5B52C523438C8FA859719EB832F58763BC |texte= Blood group A and D negativity are associated with symptomatic West Nile virus infection }}
This area was generated with Dilib version V0.6.33. |