Angiotensin-converting enzyme 2 protects from severe acute lung failure
Identifieur interne : 001698 ( Istex/Curation ); précédent : 001697; suivant : 001699Angiotensin-converting enzyme 2 protects from severe acute lung failure
Auteurs : Yumiko Imai [Autriche] ; Keiji Kuba [Autriche] ; Shuan Rao [République populaire de Chine] ; Yi Huan [République populaire de Chine] ; Feng Guo [République populaire de Chine] ; Bin Guan [République populaire de Chine] ; Peng Yang [République populaire de Chine] ; Renu Sarao [Autriche] ; Teiji Wada [Autriche] ; Howard Leong-Poi [Canada] ; Michael A. Crackower [Canada] ; Akiyoshi Fukamizu [Japon] ; Chi-Chung Hui [Canada] ; Lutz Hein [Allemagne] ; Stefan Uhlig [Allemagne] ; Arthur S. Slutsky [Canada] ; Chengyu Jiang [République populaire de Chine] ; Josef M. Penninger [Autriche]Source :
- Nature [ 0028-0836 ] ; 2005-07-07.
Url:
DOI: 10.1038/nature03712
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Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Guan, Bin" sort="Guan, Bin" uniqKey="Guan B" first="Bin" last="Guan">Bin Guan</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Peng" sort="Yang, Peng" uniqKey="Yang P" first="Peng" last="Yang">Peng Yang</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Sarao, Renu" sort="Sarao, Renu" uniqKey="Sarao R" first="Renu" last="Sarao">Renu Sarao</name><affiliation wicri:level="1"><mods:affiliation>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030</wicri:regionArea></affiliation></author><author><name sortKey="Wada, Teiji" sort="Wada, Teiji" uniqKey="Wada T" first="Teiji" last="Wada">Teiji Wada</name><affiliation wicri:level="1"><mods:affiliation>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030</wicri:regionArea></affiliation></author><author><name sortKey="Leong Poi, Howard" sort="Leong Poi, Howard" uniqKey="Leong Poi H" first="Howard" last="Leong-Poi">Howard Leong-Poi</name><affiliation wicri:level="1"><mods:affiliation>Department of Cardiology, St. Michael's Hospital, Toronto, Ontario M5B 1W8, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Cardiology, St. Michael's Hospital, Toronto, Ontario M5B 1W8</wicri:regionArea></affiliation></author><author><name sortKey="Crackower, Michael A" sort="Crackower, Michael A" uniqKey="Crackower M" first="Michael A." last="Crackower">Michael A. 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wicri:level="1"><mods:affiliation>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030</wicri:regionArea></affiliation><affiliation><mods:affiliation>*These authors contributed equally to this work</mods:affiliation></affiliation></author><author><name sortKey="Rao, Shuan" sort="Rao, Shuan" uniqKey="Rao S" first="Shuan" last="Rao">Shuan Rao</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Huan, Yi" sort="Huan, Yi" uniqKey="Huan Y" first="Yi" last="Huan">Yi Huan</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Guo, Feng" sort="Guo, Feng" uniqKey="Guo F" first="Feng" last="Guo">Feng Guo</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Guan, Bin" sort="Guan, Bin" uniqKey="Guan B" first="Bin" last="Guan">Bin Guan</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Yang, Peng" sort="Yang, Peng" uniqKey="Yang P" first="Peng" last="Yang">Peng Yang</name><affiliation wicri:level="1"><mods:affiliation>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005, China</mods:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005</wicri:regionArea></affiliation></author><author><name sortKey="Sarao, Renu" sort="Sarao, Renu" uniqKey="Sarao R" first="Renu" last="Sarao">Renu Sarao</name><affiliation wicri:level="1"><mods:affiliation>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030</wicri:regionArea></affiliation></author><author><name sortKey="Wada, Teiji" sort="Wada, Teiji" uniqKey="Wada T" first="Teiji" last="Wada">Teiji Wada</name><affiliation wicri:level="1"><mods:affiliation>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030, Austria</mods:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>IMBA, Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna A-1030</wicri:regionArea></affiliation></author><author><name sortKey="Leong Poi, Howard" sort="Leong Poi, Howard" uniqKey="Leong Poi H" first="Howard" last="Leong-Poi">Howard Leong-Poi</name><affiliation wicri:level="1"><mods:affiliation>Department of Cardiology, St. Michael's Hospital, Toronto, Ontario M5B 1W8, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Cardiology, St. Michael's Hospital, Toronto, Ontario M5B 1W8</wicri:regionArea></affiliation></author><author><name sortKey="Crackower, Michael A" sort="Crackower, Michael A" uniqKey="Crackower M" first="Michael A." last="Crackower">Michael A. Crackower</name><affiliation wicri:level="1"><mods:affiliation>Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Montreal, Quebec H3R 4P8, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Montreal, Quebec H3R 4P8</wicri:regionArea></affiliation></author><author><name sortKey="Fukamizu, Akiyoshi" sort="Fukamizu, Akiyoshi" uniqKey="Fukamizu A" first="Akiyoshi" last="Fukamizu">Akiyoshi Fukamizu</name><affiliation wicri:level="1"><mods:affiliation>Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577, Japan</mods:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Center for Tsukuba Advanced Research Alliance, University of Tsukuba, Tsukuba 305-8577</wicri:regionArea></affiliation></author><author><name sortKey="Hui, Chi Chung" sort="Hui, Chi Chung" uniqKey="Hui C" first="Chi-Chung" last="Hui">Chi-Chung Hui</name><affiliation wicri:level="1"><mods:affiliation>Program in Developmental Biology, The Hospital for Sick Children and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario MG5 1X8, Canada</mods:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Program in Developmental Biology, The Hospital for Sick Children and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario MG5 1X8</wicri:regionArea></affiliation></author><author><name sortKey="Hein, Lutz" sort="Hein, Lutz" uniqKey="Hein L" first="Lutz" last="Hein">Lutz Hein</name><affiliation wicri:level="1"><mods:affiliation>Department of Pharmacology, University of Freiburg, Freiburg 79104, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Pharmacology, University of Freiburg, Freiburg 79104</wicri:regionArea></affiliation></author><author><name sortKey="Uhlig, Stefan" sort="Uhlig, Stefan" uniqKey="Uhlig S" first="Stefan" last="Uhlig">Stefan Uhlig</name><affiliation wicri:level="1"><mods:affiliation>Division of Pulmonary Pharmacology, Research Center Borstel, Borstel 23845, Germany</mods:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Pulmonary Pharmacology, Research Center Borstel, Borstel 23845</wicri:regionArea></affiliation></author><author><name sortKey="Slutsky, Arthur S" sort="Slutsky, Arthur S" uniqKey="Slutsky A" first="Arthur S." last="Slutsky">Arthur S. 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