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Experience of a screening centre for influenza A/H1N1: the first 50 days

Identifieur interne : 000C60 ( Istex/Curation ); précédent : 000C59; suivant : 000C61

Experience of a screening centre for influenza A/H1N1: the first 50 days

Auteurs : W L Chan [Singapour] ; H K Goh [Singapour] ; A. Vasu [Singapour] ; B L Lim [Singapour] ; E. Seow [Singapour]

Source :

Emergency Medicine Journal [ 1472-0205 ] ; 2011-01.

RBID : ISTEX:1C3D23B41982FDCDCD44BE7344C62BB60AAB0D79

English descriptors

Teeft :
- Blood cells haemoglobin platelet lymphocytes chest, Cases symptom onset, Centre, Chills diarrhoea, Clinical factors, Clinical investigations, Communicable disease centre, Conjunctivitis epistaxis conditions lung diseases, Consecutive patients, Contact history, Decon, Decon areas, Decontamination chamber, Descriptive statistics, Detectable viruses, Diastolic blood pressure, Diastolic pressure, Disease control, Disorder liver disease, Disposition status, Emerg, Emergency department, Emergency department consultation area, Emergency medicine, Females ethnicity chinese others indian malay exposure travel history, Fever cough, Full blood count, Future research, Human services, Infection control measures, Laboratory characteristics, Laboratory factors, Laboratory features, Liver failure, Lymphocyte counts, Manifestations history, Median, Median platelet, Median time, Original article, Original article table, Other hospitalz, Pain nausea, Pandemic, Pandemic preparedness plans, Patient load, Patient population, Primary care, Public health emergency, Regions contact history, Respiratory rate, Respiratory symptoms, Respiratory syndrome, Screening, Screening centre, Screening experience, Screening process, Screening tool, Sore throat, Study period, Surgical masks, Symptom, Symptom onset, Symptomatic patients, Systolic pressure, Throat rhinorrhoea headache body, Throat swabs, Tock seng hospital, Travel history, Univariate analysis, World health organization.

Abstract

Background The authors' emergency department (ED) served as Singapore's screening centre for influenza H1N1 cases. The aims of the study were to describe their screening experience and to compare clinical and laboratory features of H1N1 versus seasonal flu cases. Methodology The authors conducted a prospective observational study on consecutive patients aged 16 years and above presenting to a busy, urban ED for H1N1 screening over 50 days. Clinical, laboratory, radiological and PCR data were collected from the hospital electronic databases. Primary outcomes were proportions of confirmed H1N1 cases and their distribution of clinical, laboratory and radiological features. Secondary outcomes were comparison of clinical and laboratory features of H1N1 versus seasonal flu cases. Data were analysed using descriptive statistics and univariate analysis was used to compare factors between the two groups. A p value <0.05 was considered statistically significant. Results 1205 patients were screened. 31 (2.6%) and 133 (11%) of them had H1N1 and seasonal flu infections, respectively. The two groups had similar symptoms. There were six clinical and two laboratory features with statistically significant differences between H1N1 and seasonal flu cases. Clinical factors were travel or contact history, median age, respiratory rate, diastolic blood pressure and length of hospital stay. Laboratory factors were median platelet and lymphocyte counts. Conclusions The authors report their experience as the nation's H1N1 screening centre. They identified factors that were different between H1N1 and seasonal flu cases. Future research is needed to elucidate if and how this information can be used as a screening tool for H1N1.

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https://api.istex.fr/ark:/67375/NVC-V1XGZV3J-G/fulltext.pdf

DOI: 10.1136/emj.2009.083956

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<front><div type="abstract">Background The authors' emergency department (ED) served as Singapore's screening centre for influenza H1N1 cases. The aims of the study were to describe their screening experience and to compare clinical and laboratory features of H1N1 versus seasonal flu cases. Methodology The authors conducted a prospective observational study on consecutive patients aged 16 years and above presenting to a busy, urban ED for H1N1 screening over 50 days. Clinical, laboratory, radiological and PCR data were collected from the hospital electronic databases. Primary outcomes were proportions of confirmed H1N1 cases and their distribution of clinical, laboratory and radiological features. Secondary outcomes were comparison of clinical and laboratory features of H1N1 versus seasonal flu cases. Data were analysed using descriptive statistics and univariate analysis was used to compare factors between the two groups. A p value <0.05 was considered statistically significant. Results 1205 patients were screened. 31 (2.6%) and 133 (11%) of them had H1N1 and seasonal flu infections, respectively. The two groups had similar symptoms. There were six clinical and two laboratory features with statistically significant differences between H1N1 and seasonal flu cases. Clinical factors were travel or contact history, median age, respiratory rate, diastolic blood pressure and length of hospital stay. Laboratory factors were median platelet and lymphocyte counts. Conclusions The authors report their experience as the nation's H1N1 screening centre. They identified factors that were different between H1N1 and seasonal flu cases. Future research is needed to elucidate if and how this information can be used as a screening tool for H1N1.</div>
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Experience of a screening centre for influenza A/H1N1: the first 50 days

Experience of a screening centre for influenza A/H1N1: the first 50 days

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