Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China
Identifieur interne : 000618 ( Istex/Curation ); précédent : 000617; suivant : 000619Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China
Auteurs : Susan S. Chiu [République populaire de Chine] ; Kwok Hung Chan [République populaire de Chine] ; Ka Wing Chu [République populaire de Chine] ; See Wai Kwan [République populaire de Chine] ; Yi Guan [République populaire de Chine] ; Leo Lit Man Poon [République populaire de Chine] ; J. S. M. Peiris [République populaire de Chine, Hong Kong]Source :
- Clinical Infectious Diseases [ 1058-4838 ] ; 2005.
Abstract
Background. Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43). Methods. We investigated the role that HCoV-NL63, HCoV-OC43, and HCoV-229E played in children hospitalized with fever and acute respiratory symptoms in Hong Kong during the period from August 2001 through August 2002. Results. Coronavirus infections were detected in 26 (4.4%) of 587 children studied; 15 (2.6%) were positive for HCoV-NL63, 9 (1.5%) were positive for HCoV-OC43, and 2 (0.3%) were positive for HCoV-229E. In addition to causing upper respiratory disease, we found that HCoV-NL63 can present as croup, asthma exacerbation, febrile seizures, and high fever. The mean age (± standard deviation [SD]) of the infected children was 30.7 ± 19.8 months (range, 6–57 months). The mean maximum temperature (±SD) for the 12 children who were febrile was 39.3°C ± 0.9°C, and the mean total duration of fever (±SD) for all children was 2.6 ± 1.2 days (range, 1–5 days). HCoV-NL63 infections were noted in the spring and summer months of 2002, whereas HCoV-OC43 infection mainly occurred in the fall and winter months of 2001. HCoV-NL63 viruses appeared to cluster into 2 evolutionary lineages, and viruses from both lineages cocirculated in the same season. Conclusions. HCoV-NL63 is a significant pathogen that contributes to the hospitalization of children, and it was estimated to have caused 224 hospital admissions per 100,000 population aged ⩽6 years each year in Hong Kong.
Url:
DOI: 10.1086/430301
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000618
Links to Exploration step
ISTEX:1B6A2802D03B86FA7217260054DBA4B1C438D974Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title>Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China</title>
<author><name sortKey="Chiu, Susan S" sort="Chiu, Susan S" uniqKey="Chiu S" first="Susan S." last="Chiu">Susan S. Chiu</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Paediatrics and Adolescent Medicine, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Paediatrics and Adolescent Medicine</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hung Chan, Kwok" sort="Hung Chan, Kwok" uniqKey="Hung Chan K" first="Kwok" last="Hung Chan">Kwok Hung Chan</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wing Chu, Ka" sort="Wing Chu, Ka" uniqKey="Wing Chu K" first="Ka" last="Wing Chu">Ka Wing Chu</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Man Poon, Leo Lit" sort="Man Poon, Leo Lit" uniqKey="Man Poon L" first="Leo Lit" last="Man Poon">Leo Lit Man Poon</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J. S. M." last="Peiris">J. S. M. Peiris</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>E-mail: malik@hkucc.hku.hk</mods:affiliation>
<country wicri:rule="url">Hong Kong</country>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Reprints or correspondence: Dr. J. S. M. Peiris, Dept. of Microbiology, The University Pathology Building, Queen Mary Hospital, 102 Pokfulam Rd., Pokfulam, Hong Kong SAR, China (malik@hkucc.hku.hk).</mods:affiliation>
<country wicri:rule="url">Hong Kong</country>
<wicri:regionArea>Reprints or correspondence: Dr. J. S. M. Peiris, Dept. of Microbiology, The University Pathology Building, Queen Mary Hospital, 102 Pokfulam Rd., Pokfulam, Hong Kong SAR</wicri:regionArea>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:1B6A2802D03B86FA7217260054DBA4B1C438D974</idno>
<date when="2005" year="2005">2005</date>
<idno type="doi">10.1086/430301</idno>
<idno type="url">https://api.istex.fr/ark:/67375/HXZ-WRBZMT2X-V/fulltext.pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000618</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000618</idno>
<idno type="wicri:Area/Istex/Curation">000618</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main">Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China</title>
<author><name sortKey="Chiu, Susan S" sort="Chiu, Susan S" uniqKey="Chiu S" first="Susan S." last="Chiu">Susan S. Chiu</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Paediatrics and Adolescent Medicine, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Paediatrics and Adolescent Medicine</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Hung Chan, Kwok" sort="Hung Chan, Kwok" uniqKey="Hung Chan K" first="Kwok" last="Hung Chan">Kwok Hung Chan</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Wing Chu, Ka" sort="Wing Chu, Ka" uniqKey="Wing Chu K" first="Ka" last="Wing Chu">Ka Wing Chu</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Kwan, See Wai" sort="Kwan, See Wai" uniqKey="Kwan S" first="See Wai" last="Kwan">See Wai Kwan</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Guan, Yi" sort="Guan, Yi" uniqKey="Guan Y" first="Yi" last="Guan">Yi Guan</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Man Poon, Leo Lit" sort="Man Poon, Leo Lit" uniqKey="Man Poon L" first="Leo Lit" last="Man Poon">Leo Lit Man Poon</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
</author>
<author><name sortKey="Peiris, J S M" sort="Peiris, J S M" uniqKey="Peiris J" first="J. S. M." last="Peiris">J. S. M. Peiris</name>
<affiliation wicri:level="1"><mods:affiliation>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China</mods:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Departments of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>E-mail: malik@hkucc.hku.hk</mods:affiliation>
<country wicri:rule="url">Hong Kong</country>
</affiliation>
<affiliation wicri:level="1"><mods:affiliation>Reprints or correspondence: Dr. J. S. M. Peiris, Dept. of Microbiology, The University Pathology Building, Queen Mary Hospital, 102 Pokfulam Rd., Pokfulam, Hong Kong SAR, China (malik@hkucc.hku.hk).</mods:affiliation>
<country wicri:rule="url">Hong Kong</country>
<wicri:regionArea>Reprints or correspondence: Dr. J. S. M. Peiris, Dept. of Microbiology, The University Pathology Building, Queen Mary Hospital, 102 Pokfulam Rd., Pokfulam, Hong Kong SAR</wicri:regionArea>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j" type="main">Clinical Infectious Diseases</title>
<title level="j" type="abbrev">Clinical Infectious Diseases</title>
<idno type="ISSN">1058-4838</idno>
<idno type="eISSN">1537-6591</idno>
<imprint><publisher>The University of Chicago Press</publisher>
<date type="published">2005</date>
<biblScope unit="vol">40</biblScope>
<biblScope unit="issue">12</biblScope>
<biblScope unit="page" from="1721">1721</biblScope>
<biblScope unit="page" to="1729">1729</biblScope>
</imprint>
<idno type="ISSN">1058-4838</idno>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1058-4838</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract">Background. Human coronavirus NL63 (HCoV-NL63) is a recently discovered human coronavirus found to cause respiratory illness in children and adults that is distinct from the severe acute respiratory syndrome (SARS) coronavirus and human coronaviruses 229E (HCoV-229E) and OC43 (HCoV-OC43). Methods. We investigated the role that HCoV-NL63, HCoV-OC43, and HCoV-229E played in children hospitalized with fever and acute respiratory symptoms in Hong Kong during the period from August 2001 through August 2002. Results. Coronavirus infections were detected in 26 (4.4%) of 587 children studied; 15 (2.6%) were positive for HCoV-NL63, 9 (1.5%) were positive for HCoV-OC43, and 2 (0.3%) were positive for HCoV-229E. In addition to causing upper respiratory disease, we found that HCoV-NL63 can present as croup, asthma exacerbation, febrile seizures, and high fever. The mean age (± standard deviation [SD]) of the infected children was 30.7 ± 19.8 months (range, 6–57 months). The mean maximum temperature (±SD) for the 12 children who were febrile was 39.3°C ± 0.9°C, and the mean total duration of fever (±SD) for all children was 2.6 ± 1.2 days (range, 1–5 days). HCoV-NL63 infections were noted in the spring and summer months of 2002, whereas HCoV-OC43 infection mainly occurred in the fall and winter months of 2001. HCoV-NL63 viruses appeared to cluster into 2 evolutionary lineages, and viruses from both lineages cocirculated in the same season. Conclusions. HCoV-NL63 is a significant pathogen that contributes to the hospitalization of children, and it was estimated to have caused 224 hospital admissions per 100,000 population aged ⩽6 years each year in Hong Kong.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Istex/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000618 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Curation/biblio.hfd -nk 000618 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Sante |area= SrasV1 |flux= Istex |étape= Curation |type= RBID |clé= ISTEX:1B6A2802D03B86FA7217260054DBA4B1C438D974 |texte= Human Coronavirus NL63 Infection and Other Coronavirus Infections in Children Hospitalized with Acute Respiratory Disease in Hong Kong, China }}
![]() | This area was generated with Dilib version V0.6.33. | ![]() |