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Real-time epidemic forecasting for pandemic influenza

Identifieur interne : 001B29 ( Istex/Corpus ); précédent : 001B28; suivant : 001B30

Real-time epidemic forecasting for pandemic influenza

Auteurs : I. M. Hall ; R. Gani ; H. E. Hughes ; S. Leach

Source :

RBID : ISTEX:5275DA8662769F1A159639AF77C4D46D6AC1F653

Abstract

The ongoing worldwide spread of the H5N1 influenza virus in birds has increased concerns of a new human influenza pandemic and a number of surveillance initiatives are planned, or are in place, to monitor the impact of a pandemic in near real-time. Using epidemiological data collected during the early stages of an outbreak, we show how the timing of the maximum prevalence of the pandemic wave, along with its amplitude and duration, might be predicted by fitting a mass-action epidemic model to the surveillance data by standard regression analysis. This method is validated by applying the model to routine data collected in the United Kingdom during the different waves of the previous three pandemics. The success of the method in forecasting historical prevalence suggests that such outbreaks conform reasonably well to the theoretical model, a factor which may be exploited in a future pandemic to update ongoing planning and response.

Url:
DOI: 10.1017/S0950268806007084

Links to Exploration step

ISTEX:5275DA8662769F1A159639AF77C4D46D6AC1F653

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