Current ethical issues in HIV/AIDS research and HIV/AIDS care
Identifieur interne : 001A67 ( Istex/Corpus ); précédent : 001A66; suivant : 001A68Current ethical issues in HIV/AIDS research and HIV/AIDS care
Auteurs : P. HlongwaSource :
- Oral Diseases [ 1354-523X ] ; 2016-04.
Abstract
HIV/AIDS is a global public health concern with more than 30 million deaths having been reported. Over 70% of the 35 million people with HIV/AIDS live in sub‐Saharan Africa. The current available antiretroviral treatments are limited because they do not cure but slow the progression of disease. Therefore, care and treatment for HIV/AIDS and its related research, especially in HIV‐preventive vaccine trials, require stringent ethical guidelines because of the vulnerability of the affected individuals as it with all clinical trials. These guidelines should incorporate the basic principles in ethics which include autonomy of individuals, beneficence, non‐malfeasance and justice in the care and participation of individuals in research. With at least one in five African adults infected with the disease living in sub‐Saharan Africa, this review will discuss the current ethical issues in HIV care and HIV research based on the South African context as well as exploring some of the issues globally.
Url:
DOI: 10.1111/odi.12391
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ISTEX:E0838B9BF4520BC8048DC556BF3A3493E876E843Le document en format XML
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Hlongwa</name><affiliation><mods:affiliation>School of Oral Health Sciences, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: phumzile.hlongwa@wits.ac.za</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Oral Diseases</title><title level="j" type="sub">The Mouth and AIDS: Lessons Learned and Emerging Challenges in Global Oral Health. 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Therefore, care and treatment for HIV/AIDS and its related research, especially in HIV‐preventive vaccine trials, require stringent ethical guidelines because of the vulnerability of the affected individuals as it with all clinical trials. These guidelines should incorporate the basic principles in ethics which include autonomy of individuals, beneficence, non‐malfeasance and justice in the care and participation of individuals in research. 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Published by John Wiley & Sons Ltd</copyright><eventGroup><event date="2015-02-16" type="manuscriptReceived"></event><event date="2015-10-22" type="manuscriptRevised"></event><event date="2016-02-03" type="manuscriptAccepted"></event><event agent="SPS" date="2015-12-12" type="xmlCreated"></event><event type="firstOnline" date="2016-04-25"></event><event type="publishedOnlineFinalForm" date="2016-04-25"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:5.0.6 mode:FullText" date="2017-02-10"></event></eventGroup><numberingGroup><numbering type="pageFirst">61</numbering><numbering type="pageLast">65</numbering></numberingGroup><correspondenceTo>Correspondence: P Hlongwa, School of Oral Health Sciences, Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa. 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Over 70% of the 35 million people with <fc>HIV</fc>/<fc>AIDS</fc> live in sub‐<fc>S</fc>aharan <fc>A</fc>frica. The current available antiretroviral treatments are limited because they do not cure but slow the progression of disease. Therefore, care and treatment for <fc>HIV</fc>/<fc>AIDS</fc> and its related research, especially in <fc>HIV</fc>‐preventive vaccine trials, require stringent ethical guidelines because of the vulnerability of the affected individuals as it with all clinical trials. These guidelines should incorporate the basic principles in ethics which include autonomy of individuals, beneficence, non‐malfeasance and justice in the care and participation of individuals in research. 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Over 70% of the 35 million people with HIV/AIDS live in sub‐Saharan Africa. The current available antiretroviral treatments are limited because they do not cure but slow the progression of disease. Therefore, care and treatment for HIV/AIDS and its related research, especially in HIV‐preventive vaccine trials, require stringent ethical guidelines because of the vulnerability of the affected individuals as it with all clinical trials. These guidelines should incorporate the basic principles in ethics which include autonomy of individuals, beneficence, non‐malfeasance and justice in the care and participation of individuals in research. With at least one in five African adults infected with the disease living in sub‐Saharan Africa, this review will discuss the current ethical issues in HIV care and HIV research based on the South African context as well as exploring some of the issues globally.</abstract><subject><genre>keywords</genre><topic>HIV/AIDS Research Ethics</topic><topic>HIV/AIDS Clinical Care Ethics</topic><topic>Basic Ethical Principles</topic></subject><relatedItem type="host"><titleInfo><title>Oral Diseases</title></titleInfo><titleInfo type="abbreviated"><title>Oral Dis</title></titleInfo><name type="personal"><namePart type="given">Anwar R.</namePart><namePart type="family">Tappuni</namePart><role><roleTerm type="text">editor</roleTerm></role></name><name type="personal"><namePart type="given">Stephen J.</namePart><namePart type="family">Challacombe</namePart><role><roleTerm type="text">editor</roleTerm></role></name><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><subject><genre>article-category</genre><topic>Original Article</topic><topic>The Mouth and AIDS: Lessons Learned and Emerging Challenges in Global Oral Health. Seventh World Workshop on Oral Health & Disease in AIDS. Edited by Anwar R. Tappuni and Stephen J. Challacombe</topic><topic>Original articles</topic></subject><identifier type="ISSN">1354-523X</identifier><identifier type="eISSN">1601-0825</identifier><identifier type="DOI">10.1111/(ISSN)1601-0825</identifier><identifier type="PublisherID">ODI</identifier><part><date>2016</date><detail type="title"><title>The Mouth and AIDS: Lessons Learned and Emerging Challenges in Global Oral Health. Seventh World Workshop on Oral Health & Disease in AIDS</title></detail><detail type="volume"><caption>vol.</caption><number>22</number></detail><detail type="issue"><caption>Suppl. no.</caption><number>S1</number></detail><extent unit="pages"><start>61</start><end>65</end><total>5</total></extent></part></relatedItem><relatedItem type="references" displayLabel="odi12391-cit-0001"><titleInfo><title>Informed consent for HIV testing in a South African hospital: is it truly informed and truly voluntary?</title></titleInfo><name type="personal"><namePart type="given">Q</namePart><namePart type="family">Abdool Karim</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">SS</namePart><namePart type="family">Abdool Karim</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HM</namePart><namePart type="family">Coovadia</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M</namePart><namePart type="family">Susser</namePart><role><roleTerm type="text">author</roleTerm></role></name><genre>journal-article</genre><note type="citation/reference">Abdool Karim Q, Abdool Karim SS, Coovadia HM, Susser M (1998). 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