Loop‐mediated isothermal amplification method for detection of human papillomavirus type 6, 11, 16, and 18
Identifieur interne : 001062 ( Istex/Corpus ); précédent : 001061; suivant : 001063Loop‐mediated isothermal amplification method for detection of human papillomavirus type 6, 11, 16, and 18
Auteurs : Masanori Hagiwara ; Hajime Sasaki ; Koma Matsuo ; Mariko Honda ; Masaaki Kawase ; Hidemi NakagawaSource :
- Journal of Medical Virology [ 0146-6615 ] ; 2007-05.
English descriptors
- Teeft :
- Additional advantage, Agarose, Assay, Average reaction time, Blot hybridization, Bowenoid, Bowenoid papuloses, Bowenoid papulosis, Cervical cancer, Cervical carcinoma, Clin, Clin microbiol, Clinical samples, Condyloma, Condyloma acuminatum, Condylomata acuminata, Consensus primers, Copy number, Detection limit, Eiken chemical, Epidermolytic acanthoma, Ethidium bromide, Genital lesions, Genome quantity, Hairy nymphae, Herpes simplex virus, High copy numbers, Histologic diagnoses, Human papillomavirus, Human papillomavirus type, Human papillomavirus types, Human papillomaviruses, Isothermal, Isothermal method, Jikei aoto hospital, Jikei university school, Lamp method, Lamp primers, Lamp products, Lamp reaction, Linear correlation, Loop primers, Measles virus, Microbiol, Notomi, Papillomavirus, Papulosis, Polymerase chain reaction, Polypoid lesions, Positive samples, Primer, Quantitative method, Rapid detection, Rapid diagnosis, Reaction time, Respective type, Seborrheic keratosis, Serial dilutions, Turbidity, Turbidity assay, Valuable tool, Various types, Virol, Virological testing, Virus isolation, Yoshikawa.
Abstract
A new method was developed for detection of human papillomavirus (HPV) by loop‐mediated isothermal amplification (LAMP), which was compared with the polymerase chain reaction (PCR), and real‐time PCR for specificity and sensitivity. All initial validation studies with the control DNA proved to be type‐specific. In order to evaluate the reliability of HPV type‐specific LAMP detecting HPV DNA from clinical samples, tissue specimens were obtained from 27 patients with external genital polypoid lesions. The histologic diagnoses included condyloma acuminatum (n = 21), bowenoid papulosis (n = 2), seborrheic keratosis (n = 2), epidermolytic acanthoma (n = 1), and hairy nymphae (n = 1). HPV‐6 DNA and HPV‐11 DNA were detected in 18 and 3 of 21 condylomata acuminata, respectively, and there was no simultaneous infection. HPV‐16 DNA was detected in one of two bowenoid papuloses. HPV DNA was not detected in the seborrheic keratoses, epidermolytic acanthoma, and hairy nymphae. These results correlated perfectly with those from real‐time PCR analysis. Most positive samples contained high copy numbers of HPV DNA. HPV‐11 DNA was detected in one case that could not be detected by PCR. The average reaction time was about 59 min. There was a linear correlation between the genome quantity and reaction time to reach the threshold. The LAMP method has an additional advantage as a quantitative method, and is superior in terms of sensitivity, specificity, rapidity, and simplicity, and can potentially be a valuable tool for the detection of HPV DNA. J. Med. Virol. 79:605–615, 2007. © 2007 Wiley‐Liss, Inc.
Url:
DOI: 10.1002/jmv.20858
Links to Exploration step
ISTEX:2538B069494CB2B7137759C43A80E9358BCC941DLe document en format XML
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virus</term><term>Microbiol</term><term>Notomi</term><term>Papillomavirus</term><term>Papulosis</term><term>Polymerase chain reaction</term><term>Polypoid lesions</term><term>Positive samples</term><term>Primer</term><term>Quantitative method</term><term>Rapid detection</term><term>Rapid diagnosis</term><term>Reaction time</term><term>Respective type</term><term>Seborrheic keratosis</term><term>Serial dilutions</term><term>Turbidity</term><term>Turbidity assay</term><term>Valuable tool</term><term>Various types</term><term>Virol</term><term>Virological testing</term><term>Virus isolation</term><term>Yoshikawa</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">A new method was developed for detection of human papillomavirus (HPV) by loop‐mediated isothermal amplification (LAMP), which was compared with the polymerase chain reaction (PCR), and real‐time PCR for specificity and sensitivity. 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There was a linear correlation between the genome quantity and reaction time to reach the threshold. The LAMP method has an additional advantage as a quantitative method, and is superior in terms of sensitivity, specificity, rapidity, and simplicity, and can potentially be a valuable tool for the detection of HPV DNA. J. Med. 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Japan</json:string></affiliations></json:item><json:item><name>Hidemi Nakagawa</name><affiliations><json:string>Department of Dermatology, Jikei University School of Medicine, Tokyo, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>human papillomavirus (HPV)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>loop‐mediated isothermal amplification (LAMP)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>polymerase chain reaction (PCR)</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>real‐time PCR</value></json:item></subject><articleId><json:string>JMV20858</json:string></articleId><arkIstex>ark:/67375/WNG-PKC2DLGJ-G</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><abstract>A new method was developed for detection of human papillomavirus (HPV) by loop‐mediated isothermal amplification (LAMP), which was compared with the polymerase chain reaction (PCR), and real‐time PCR for specificity and sensitivity. All initial validation studies with the control DNA proved to be type‐specific. In order to evaluate the reliability of HPV type‐specific LAMP detecting HPV DNA from clinical samples, tissue specimens were obtained from 27 patients with external genital polypoid lesions. The histologic diagnoses included condyloma acuminatum (n = 21), bowenoid papulosis (n = 2), seborrheic keratosis (n = 2), epidermolytic acanthoma (n = 1), and hairy nymphae (n = 1). HPV‐6 DNA and HPV‐11 DNA were detected in 18 and 3 of 21 condylomata acuminata, respectively, and there was no simultaneous infection. HPV‐16 DNA was detected in one of two bowenoid papuloses. HPV DNA was not detected in the seborrheic keratoses, epidermolytic acanthoma, and hairy nymphae. These results correlated perfectly with those from real‐time PCR analysis. Most positive samples contained high copy numbers of HPV DNA. HPV‐11 DNA was detected in one case that could not be detected by PCR. The average reaction time was about 59 min. There was a linear correlation between the genome quantity and reaction time to reach the threshold. The LAMP method has an additional advantage as a quantitative method, and is superior in terms of sensitivity, specificity, rapidity, and simplicity, and can potentially be a valuable tool for the detection of HPV DNA. J. Med. Virol. 79:605–615, 2007. © 2007 Wiley‐Liss, Inc.</abstract><qualityIndicators><score>8.562</score><pdfWordCount>3682</pdfWordCount><pdfCharCount>23717</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>11</pdfPageCount><pdfPageSize>594 x 792 pts</pdfPageSize><pdfWordsPerPage>335</pdfWordsPerPage><pdfText>true</pdfText><refBibsNative>true</refBibsNative><abstractWordCount>240</abstractWordCount><abstractCharCount>1607</abstractCharCount><keywordCount>4</keywordCount></qualityIndicators><title>Loop‐mediated isothermal amplification method for detection of human papillomavirus type 6, 11, 16, and 18</title><pmid><json:string>17385684</json:string></pmid><genre><json:string>article</json:string></genre><host><title>Journal of Medical Virology</title><language><json:string>unknown</json:string></language><doi><json:string>10.1002/(ISSN)1096-9071</json:string></doi><issn><json:string>0146-6615</json:string></issn><eissn><json:string>1096-9071</json:string></eissn><publisherId><json:string>JMV</json:string></publisherId><volume>79</volume><issue>5</issue><pages><first>605</first><last>615</last><total>11</total></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Research Article</value></json:item></subject></host><namedEntities><unitex><date><json:string>2007</json:string><json:string>11s</json:string></date><geogName></geogName><orgName><json:string>Qiagen</json:string><json:string>Review Board of the Jikei University School of Medicine</json:string><json:string>LISS, INC</json:string><json:string>Eiken Chemical</json:string><json:string>Biotech</json:string><json:string>Wiley-Liss, Inc</json:string><json:string>Department of Dermatology, Jikei Aoto Hospital, Aoto</json:string></orgName><orgName_funder></orgName_funder><orgName_provider></orgName_provider><persName><json:string>DyNA Quant</json:string><json:string>Masanori Hagiwara</json:string><json:string>I. Comparison</json:string><json:string>Eiken Chemical</json:string><json:string>J. Med</json:string><json:string>I. Fig</json:string></persName><placeName><json:string>Foster City</json:string><json:string>Kyoto</json:string><json:string>Chatsworth</json:string><json:string>Piscataway</json:string><json:string>Helsinki</json:string><json:string>Japan</json:string><json:string>Tokyo</json:string><json:string>CA</json:string><json:string>NJ</json:string></placeName><ref_url></ref_url><ref_bibl><json:string>Poon et al., 2004</json:string><json:string>Peitsaro et al., 2002</json:string><json:string>Nagamine et al. [2002]</json:string><json:string>Okafuji et al., 2005</json:string><json:string>Hausen and de Villiers, 1994</json:string><json:string>Fujino et al., 2005</json:string><json:string>Brown et al., 1993</json:string><json:string>Notomi et al. 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[1991]</json:string><json:string>Kuboki et al., 2003</json:string><json:string>Nagamine et al., 2001</json:string><json:string>Seth et al., 2005</json:string><json:string>Yoshikawa et al., 1991</json:string><json:string>Yoshikawa et al., 2004</json:string><json:string>Cubie et al., 2001</json:string><json:string>Ho et al., 2005</json:string><json:string>Qu et al., 1997</json:string><json:string>Enomoto et al., 2005</json:string><json:string>Leung et al., 2005</json:string><json:string>Sugiyama et al., 2005</json:string><json:string>Okamoto et al., 2004</json:string><json:string>Maruyama et al., 2003</json:string><json:string>Tucker et al., 2001</json:string><json:string>Ito et al., 2006</json:string><json:string>Beutner et al., 1998</json:string><json:string>Parida et al., 2004</json:string></ref_bibl><bibl></bibl></unitex></namedEntities><ark><json:string>ark:/67375/WNG-PKC2DLGJ-G</json:string></ark><categories><wos><json:string>1 - science</json:string><json:string>2 - 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‐18</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><availability><licence>Copyright © 2007 Wiley‐Liss, Inc.</licence></availability><date type="published" when="2007-05"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Loop‐mediated isothermal amplification method for detection of human papillomavirus type 6, 11, 16, and 18</title><title level="a" type="short" xml:lang="en">LAMP for Detection of HPV‐6, ‐11, ‐16, and ‐18</title><author xml:id="author-0000" role="corresp"><persName><forename type="first">Masanori</forename><surname>Hagiwara</surname></persName><email>hagimasa@jikei.ac.jp</email><affiliation><orgName type="department">Department of Dermatology</orgName><orgName type="institution">Jikei Aoto Hospital</orgName><address><addrLine>Tokyo</addrLine><addrLine>Japan</addrLine><country key="JP" xml:lang="en">JAPAN</country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">Hajime</forename><surname>Sasaki</surname></persName><affiliation><orgName type="department">Department of Dermatology</orgName><orgName type="institution">Jikei Aoto Hospital</orgName><address><addrLine>Tokyo</addrLine><addrLine>Japan</addrLine><country key="JP" xml:lang="en">JAPAN</country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Koma</forename><surname>Matsuo</surname></persName><affiliation><orgName type="department">Department of Dermatology</orgName><orgName type="institution">Jikei Aoto Hospital</orgName><address><addrLine>Tokyo</addrLine><addrLine>Japan</addrLine><country key="JP" xml:lang="en">JAPAN</country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">Mariko</forename><surname>Honda</surname></persName><affiliation><orgName type="department">Department of Dermatology</orgName><orgName type="institution">Jikei Aoto Hospital</orgName><address><addrLine>Tokyo</addrLine><addrLine>Japan</addrLine><country key="JP" xml:lang="en">JAPAN</country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">Masaaki</forename><surname>Kawase</surname></persName><affiliation><orgName type="department">Department of Dermatology</orgName><orgName type="institution">Jikei University School of Medicine</orgName><address><addrLine>Tokyo</addrLine><addrLine>Japan</addrLine><country key="JP" xml:lang="en">JAPAN</country></address></affiliation></author><author xml:id="author-0005"><persName><forename 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HPV‐16 DNA was detected in one of two bowenoid papuloses. HPV DNA was not detected in the seborrheic keratoses, epidermolytic acanthoma, and hairy nymphae. These results correlated perfectly with those from real‐time PCR analysis. Most positive samples contained high copy numbers of HPV DNA. HPV‐11 DNA was detected in one case that could not be detected by PCR. The average reaction time was about 59 min. There was a linear correlation between the genome quantity and reaction time to reach the threshold. The LAMP method has an additional advantage as a quantitative method, and is superior in terms of sensitivity, specificity, rapidity, and simplicity, and can potentially be a valuable tool for the detection of HPV DNA. J. Med. Virol. 79:605–615, 2007. © 2007 Wiley‐Liss, Inc.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="kwd1">human papillomavirus (HPV)</term><term xml:id="kwd2">loop‐mediated isothermal amplification (LAMP)</term><term xml:id="kwd3">polymerase chain reaction (PCR)</term><term xml:id="kwd4">real‐time PCR</term></keywords><keywords rend="articleCategory"><term>Research Article</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc><revisionDesc><change when="2019-12-20" who="#istex" xml:id="pub2tei">formatting</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/WNG-PKC2DLGJ-G/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Wiley Subscription Services, Inc., A Wiley Company</publisherName><publisherLoc>Hoboken</publisherLoc></publisherInfo><doi registered="yes">10.1002/(ISSN)1096-9071</doi><issn type="print">0146-6615</issn><issn type="electronic">1096-9071</issn><idGroup><id type="product" value="JMV"></id></idGroup><titleGroup><title type="main" xml:lang="en" sort="JOURNAL OF MEDICAL VIROLOGY">Journal of Medical Virology</title><title type="short">J. 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All initial validation studies with the control DNA proved to be type‐specific. In order to evaluate the reliability of HPV type‐specific LAMP detecting HPV DNA from clinical samples, tissue specimens were obtained from 27 patients with external genital polypoid lesions. The histologic diagnoses included condyloma acuminatum (n = 21), bowenoid papulosis (n = 2), seborrheic keratosis (n = 2), epidermolytic acanthoma (n = 1), and hairy nymphae (n = 1). HPV‐6 DNA and HPV‐11 DNA were detected in 18 and 3 of 21 condylomata acuminata, respectively, and there was no simultaneous infection. HPV‐16 DNA was detected in one of two bowenoid papuloses. HPV DNA was not detected in the seborrheic keratoses, epidermolytic acanthoma, and hairy nymphae. These results correlated perfectly with those from real‐time PCR analysis. Most positive samples contained high copy numbers of HPV DNA. HPV‐11 DNA was detected in one case that could not be detected by PCR. The average reaction time was about 59 min. There was a linear correlation between the genome quantity and reaction time to reach the threshold. The LAMP method has an additional advantage as a quantitative method, and is superior in terms of sensitivity, specificity, rapidity, and simplicity, and can potentially be a valuable tool for the detection of HPV DNA. J. Med. Virol. 79:605–615, 2007. © 2007 Wiley‐Liss, Inc.</p></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Loop‐mediated isothermal amplification method for detection of human papillomavirus type 6, 11, 16, and 18</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>LAMP for Detection of HPV‐6, ‐11, ‐16, and ‐18</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Loop‐mediated isothermal amplification method for detection of human papillomavirus type 6, 11, 16, and 18</title></titleInfo><name type="personal"><namePart type="given">Masanori</namePart><namePart type="family">Hagiwara</namePart><affiliation>Department of Dermatology, Jikei Aoto Hospital, Tokyo, Japan</affiliation><affiliation>E-mail: hagimasa@jikei.ac.jp</affiliation><affiliation>Correspondence address: Department of Dermatology, Jikei Aoto Hospital, Aoto 6‐41‐2, Katsusika‐ku, Tokyo, 125‐8506, Japan.===</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hajime</namePart><namePart type="family">Sasaki</namePart><affiliation>Department of Dermatology, Jikei Aoto Hospital, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Koma</namePart><namePart type="family">Matsuo</namePart><affiliation>Department of Dermatology, Jikei Aoto Hospital, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mariko</namePart><namePart type="family">Honda</namePart><affiliation>Department of Dermatology, Jikei Aoto Hospital, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Masaaki</namePart><namePart type="family">Kawase</namePart><affiliation>Department of Dermatology, Jikei University School of Medicine, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hidemi</namePart><namePart type="family">Nakagawa</namePart><affiliation>Department of Dermatology, Jikei University School of Medicine, Tokyo, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><place><placeTerm type="text">Hoboken</placeTerm></place><dateIssued encoding="w3cdtf">2007-05</dateIssued><dateValid encoding="w3cdtf">2006-12-06</dateValid><copyrightDate encoding="w3cdtf">2007</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">4</extent><extent unit="tables">1</extent><extent unit="references">33</extent><extent unit="words">1073</extent></physicalDescription><abstract lang="en">A new method was developed for detection of human papillomavirus (HPV) by loop‐mediated isothermal amplification (LAMP), which was compared with the polymerase chain reaction (PCR), and real‐time PCR for specificity and sensitivity. All initial validation studies with the control DNA proved to be type‐specific. In order to evaluate the reliability of HPV type‐specific LAMP detecting HPV DNA from clinical samples, tissue specimens were obtained from 27 patients with external genital polypoid lesions. The histologic diagnoses included condyloma acuminatum (n = 21), bowenoid papulosis (n = 2), seborrheic keratosis (n = 2), epidermolytic acanthoma (n = 1), and hairy nymphae (n = 1). HPV‐6 DNA and HPV‐11 DNA were detected in 18 and 3 of 21 condylomata acuminata, respectively, and there was no simultaneous infection. HPV‐16 DNA was detected in one of two bowenoid papuloses. HPV DNA was not detected in the seborrheic keratoses, epidermolytic acanthoma, and hairy nymphae. These results correlated perfectly with those from real‐time PCR analysis. Most positive samples contained high copy numbers of HPV DNA. HPV‐11 DNA was detected in one case that could not be detected by PCR. The average reaction time was about 59 min. There was a linear correlation between the genome quantity and reaction time to reach the threshold. The LAMP method has an additional advantage as a quantitative method, and is superior in terms of sensitivity, specificity, rapidity, and simplicity, and can potentially be a valuable tool for the detection of HPV DNA. J. Med. Virol. 79:605–615, 2007. © 2007 Wiley‐Liss, Inc.</abstract><subject lang="en"><genre>keywords</genre><topic>human papillomavirus (HPV)</topic><topic>loop‐mediated isothermal amplification (LAMP)</topic><topic>polymerase chain reaction (PCR)</topic><topic>real‐time PCR</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Medical Virology</title></titleInfo><titleInfo type="abbreviated"><title>J. Med. 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