Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS
Identifieur interne : 000A48 ( Istex/Corpus ); précédent : 000A47; suivant : 000A49Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS
Auteurs : Jiao Qiang ; Wang Biao ; Zhang Rui-Lin ; Wang Bao-Guo ; Feng Li-Min ; Wang Hai-Jian ; Luo Yan-Nan ; Yan Xiong ; Shen Hong-Qiang ; Ma Ying-Min ; Xiong Yun ; Chen Wei-Heng ; Ma Da ; Cheng Ting ; Zhou WeiSource :
- Chinese Journal of Integrative Medicine [ 1672-0415 ] ; 2003-09-01.
English descriptors
- KwdEn :
Abstract
Abstract: Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients.Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc., on the basis of “Recommended Protocol for Infectious Atypical Pneumonia” (abbreviated as “Recommended Protocol”) issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in “Special Science and Technological Action to Prevent and Treat SARS” (abbreviated as “Special S-T Action”), issued by Ministry of Science and Technology, together with the same WM as those for the control group.Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively,P < 0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference,P > 0.05; (3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P < 0. 05).Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.
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DOI: 10.1007/BF02838027
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Rui-Lin</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Bao Guo, Wang" sort="Bao Guo, Wang" uniqKey="Bao Guo W" first="Wang" last="Bao-Guo">Wang Bao-Guo</name><affiliation><mods:affiliation>Beijing Tiantan Hospital, China</mods:affiliation></affiliation></author><author><name sortKey="Li Min, Feng" sort="Li Min, Feng" uniqKey="Li Min F" first="Feng" last="Li-Min">Feng Li-Min</name><affiliation><mods:affiliation>Beijing Tiantan Hospital, China</mods:affiliation></affiliation></author><author><name sortKey="Hai Jian, Wang" sort="Hai Jian, Wang" uniqKey="Hai Jian W" first="Wang" last="Hai-Jian">Wang Hai-Jian</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Yan Nan, Luo" sort="Yan Nan, Luo" uniqKey="Yan Nan L" first="Luo" 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Beijing</mods:affiliation></affiliation></author><author><name sortKey="Yun, Xiong" sort="Yun, Xiong" uniqKey="Yun X" first="Xiong" last="Yun">Xiong Yun</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Wei Heng, Chen" sort="Wei Heng, Chen" uniqKey="Wei Heng C" first="Chen" last="Wei-Heng">Chen Wei-Heng</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Da, Ma" sort="Da, Ma" uniqKey="Da M" first="Ma" last="Da">Ma Da</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Ting, Cheng" sort="Ting, Cheng" uniqKey="Ting C" first="Cheng" last="Ting">Cheng Ting</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Wei, Zhou" sort="Wei, Zhou" uniqKey="Wei Z" first="Zhou" last="Wei">Zhou Wei</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:DD1F555D2EAB7C9C81C1AA91201C99AB86C8DB2E</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1007/BF02838027</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-8M2RL9GQ-D/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000A48</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000A48</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS</title><author><name sortKey="Qiang, Jiao" sort="Qiang, Jiao" uniqKey="Qiang J" first="Jiao" last="Qiang">Jiao Qiang</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: jiaoqiang@263.net</mods:affiliation></affiliation></author><author><name sortKey="Biao, Wang" sort="Biao, Wang" uniqKey="Biao W" first="Wang" last="Biao">Wang Biao</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Rui Lin, Zhang" sort="Rui Lin, Zhang" uniqKey="Rui Lin Z" first="Zhang" last="Rui-Lin">Zhang Rui-Lin</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Bao Guo, Wang" sort="Bao Guo, Wang" uniqKey="Bao Guo W" first="Wang" last="Bao-Guo">Wang Bao-Guo</name><affiliation><mods:affiliation>Beijing Tiantan Hospital, China</mods:affiliation></affiliation></author><author><name sortKey="Li Min, Feng" sort="Li Min, Feng" uniqKey="Li Min F" first="Feng" last="Li-Min">Feng Li-Min</name><affiliation><mods:affiliation>Beijing Tiantan Hospital, China</mods:affiliation></affiliation></author><author><name sortKey="Hai Jian, Wang" sort="Hai Jian, Wang" uniqKey="Hai Jian W" first="Wang" last="Hai-Jian">Wang Hai-Jian</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Yan Nan, Luo" sort="Yan Nan, Luo" uniqKey="Yan Nan L" first="Luo" last="Yan-Nan">Luo Yan-Nan</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Xiong, Yan" sort="Xiong, Yan" uniqKey="Xiong Y" first="Yan" last="Xiong">Yan Xiong</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hong Qiang, Shen" sort="Hong Qiang, Shen" uniqKey="Hong Qiang S" first="Shen" last="Hong-Qiang">Shen Hong-Qiang</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Ying Min, Ma" sort="Ying Min, Ma" uniqKey="Ying Min M" first="Ma" last="Ying-Min">Ma Ying-Min</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Yun, Xiong" sort="Yun, Xiong" uniqKey="Yun X" first="Xiong" last="Yun">Xiong Yun</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Wei Heng, Chen" sort="Wei Heng, Chen" uniqKey="Wei Heng C" first="Chen" last="Wei-Heng">Chen Wei-Heng</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Da, Ma" sort="Da, Ma" uniqKey="Da M" first="Ma" last="Da">Ma Da</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Ting, Cheng" sort="Ting, Cheng" uniqKey="Ting C" first="Cheng" last="Ting">Cheng Ting</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Wei, Zhou" sort="Wei, Zhou" uniqKey="Wei Z" first="Zhou" last="Wei">Zhou Wei</name><affiliation><mods:affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Chinese Journal of Integrative Medicine</title><title level="j" type="abbrev">Chin. J. Integr. Med.</title><idno type="ISSN">1672-0415</idno><idno type="eISSN">1993-0402</idno><imprint><publisher>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><pubPlace>Beijing</pubPlace><date type="published" when="2003-09-01">2003-09-01</date><biblScope unit="volume">9</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="175">175</biblScope><biblScope unit="page" to="180">180</biblScope></imprint><idno type="ISSN">1672-0415</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1672-0415</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>clinical study</term><term>corticosteroid</term><term>integrative Chinese and western medicine treatment</term><term>severe acute respiratory syndrome</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients.Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc., on the basis of “Recommended Protocol for Infectious Atypical Pneumonia” (abbreviated as “Recommended Protocol”) issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in “Special Science and Technological Action to Prevent and Treat SARS” (abbreviated as “Special S-T Action”), issued by Ministry of Science and Technology, together with the same WM as those for the control group.Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively,P < 0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference,P > 0.05; (3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P < 0. 05).Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>Jiao Qiang</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string><json:string>E-mail: jiaoqiang@263.net</json:string></affiliations></json:item><json:item><name>Wang Biao</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Zhang Rui-lin</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Wang Bao-guo</name><affiliations><json:string>Beijing Tiantan Hospital, China</json:string></affiliations></json:item><json:item><name>Feng Li-min</name><affiliations><json:string>Beijing Tiantan Hospital, China</json:string></affiliations></json:item><json:item><name>Wang Hai-jian</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Luo Yan-nan</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Yan Xiong</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Shen Hong-qiang</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Ma Ying-min</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Xiong Yun</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Chen Wei-heng</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Ma Da</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Cheng Ting</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item><json:item><name>Zhou Wei</name><affiliations><json:string>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>severe acute respiratory syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>integrative Chinese and western medicine treatment</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>corticosteroid</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>clinical study</value></json:item></subject><articleId><json:string>BF02838027</json:string><json:string>Art4</json:string></articleId><arkIstex>ark:/67375/VQC-8M2RL9GQ-D</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients.Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc., on the basis of “Recommended Protocol for Infectious Atypical Pneumonia” (abbreviated as “Recommended Protocol”) issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in “Special Science and Technological Action to Prevent and Treat SARS” (abbreviated as “Special S-T Action”), issued by Ministry of Science and Technology, together with the same WM as those for the control group.Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively,P > 0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference,P > 0.05; (3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P > 0. 05).Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.</abstract><qualityIndicators><score>8.56</score><pdfWordCount>3560</pdfWordCount><pdfCharCount>18757</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>6</pdfPageCount><pdfPageSize>590.424 x 806.424 pts</pdfPageSize><refBibsNative>false</refBibsNative><abstractWordCount>279</abstractWordCount><abstractCharCount>1790</abstractCharCount><keywordCount>4</keywordCount></qualityIndicators><title>Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS</title><genre><json:string>research-article</json:string></genre><host><title>Chinese Journal of Integrative 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J. Integr. Med.</title><idno type="pISSN">1672-0415</idno><idno type="eISSN">1993-0402</idno><idno type="journal-ID">true</idno><idno type="issue-article-count">24</idno><idno type="volume-issue-count">4</idno><imprint><publisher>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><pubPlace>Beijing</pubPlace><date type="published" when="2003-09-01"></date><biblScope unit="volume">9</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="175">175</biblScope><biblScope unit="page" to="180">180</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2003-06-26</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients.Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc., on the basis of “Recommended Protocol for Infectious Atypical Pneumonia” (abbreviated as “Recommended Protocol”) issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in “Special Science and Technological Action to Prevent and Treat SARS” (abbreviated as “Special S-T Action”), issued by Ministry of Science and Technology, together with the same WM as those for the control group.Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively,P < 0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference,P > 0.05; (3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P < 0. 05).Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Key Words</head><item><term>severe acute respiratory syndrome</term></item><item><term>integrative Chinese and western medicine treatment</term></item><item><term>corticosteroid</term></item><item><term>clinical study</term></item></list></keywords></textClass><textClass><keywords scheme="Journal-Subject-Group"><list><label>H</label><item><term>Medicine & Public Health</term></item><label>H00007</label><item><term>Medicine/Public Health, general</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2003-06-26">Created</change><change when="2003-09-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-8M2RL9GQ-D/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus springer-journals not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</PublisherName><PublisherLocation>Beijing</PublisherLocation></PublisherInfo><Journal><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>11655</JournalID><JournalPrintISSN>1672-0415</JournalPrintISSN><JournalElectronicISSN>1993-0402</JournalElectronicISSN><JournalTitle>Chinese Journal of Integrative Medicine</JournalTitle><JournalAbbreviatedTitle>Chin. J. Integr. Med.</JournalAbbreviatedTitle><JournalSubjectGroup><JournalSubject Type="Primary" Code="H">Medicine & Public Health</JournalSubject><JournalSubject Type="Secondary" Priority="1" Code="H00007">Medicine/Public Health, general</JournalSubject></JournalSubjectGroup></JournalInfo><Volume><VolumeInfo VolumeType="Regular" TocLevels="0"><VolumeIDStart>9</VolumeIDStart><VolumeIDEnd>9</VolumeIDEnd><VolumeIssueCount>4</VolumeIssueCount></VolumeInfo><Issue IssueType="Regular"><IssueInfo TocLevels="0"><IssueIDStart>3</IssueIDStart><IssueIDEnd>3</IssueIDEnd><IssueArticleCount>24</IssueArticleCount><IssueHistory><CoverDate><Year>2003</Year><Month>9</Month></CoverDate></IssueHistory><IssueCopyright><CopyrightHolderName>The Chinese Journal of Integrated Traditional and Western Medicine Press</CopyrightHolderName><CopyrightYear>2003</CopyrightYear></IssueCopyright></IssueInfo><Article ID="Art4"><ArticleInfo Language="En" ArticleType="OriginalPaper" NumberingStyle="Unnumbered" TocLevels="0" ContainsESM="No"><ArticleID>BF02838027</ArticleID><ArticleDOI>10.1007/BF02838027</ArticleDOI><ArticleSequenceNumber>4</ArticleSequenceNumber><ArticleTitle Language="En">Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS</ArticleTitle><ArticleCategory>Original Artical</ArticleCategory><ArticleFirstPage>175</ArticleFirstPage><ArticleLastPage>180</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2008</Year><Month>2</Month><Day>15</Day></RegistrationDate><Received><Year>2003</Year><Month>6</Month><Day>26</Day></Received></ArticleHistory><ArticleCopyright><CopyrightHolderName>The Chinese Journal of Integrated Traditional and Western Medicine Press</CopyrightHolderName><CopyrightYear>2003</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants><ArticleContext><JournalID>11655</JournalID><VolumeIDStart>9</VolumeIDStart><VolumeIDEnd>9</VolumeIDEnd><IssueIDStart>3</IssueIDStart><IssueIDEnd>3</IssueIDEnd></ArticleContext></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Jiao</GivenName><FamilyName>Qiang</FamilyName></AuthorName><Contact><Phone>010-64711199</Phone><Fax>010-64724815</Fax><Email>jiaoqiang@263.net</Email></Contact></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Wang</GivenName><FamilyName>Biao</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Zhang</GivenName><FamilyName>Rui-lin</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Wang</GivenName><FamilyName>Bao-guo</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff2"><AuthorName DisplayOrder="Western"><GivenName>Feng</GivenName><FamilyName>Li-min</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Wang</GivenName><FamilyName>Hai-jian</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Luo</GivenName><FamilyName>Yan-nan</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Yan</GivenName><FamilyName>Xiong</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Shen</GivenName><FamilyName>Hong-qiang</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Ma</GivenName><FamilyName>Ying-min</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Xiong</GivenName><FamilyName>Yun</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Chen</GivenName><FamilyName>Wei-heng</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Ma</GivenName><FamilyName>Da</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Cheng</GivenName><FamilyName>Ting</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Zhou</GivenName><FamilyName>Wei</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Wangjing Hospital</OrgDivision><OrgName>China Academy of Traditional Chinese Medicine</OrgName><OrgAddress><Postcode>100102</Postcode><City>Beijing</City></OrgAddress></Affiliation><Affiliation ID="Aff2"><OrgName>Beijing Tiantan Hospital</OrgName><OrgAddress><Country>China</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para><Emphasis Type="Bold">Objective</Emphasis>: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients.<Emphasis Type="Bold">Methods</Emphasis>: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc., on the basis of “Recommended Protocol for Infectious Atypical Pneumonia” (abbreviated as “Recommended Protocol”) issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in “Special Science and Technological Action to Prevent and Treat SARS” (abbreviated as “Special S-T Action”), issued by Ministry of Science and Technology, together with the same WM as those for the control group.<Emphasis Type="Bold">Results</Emphasis>: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively,<Emphasis Type="Italic">P</Emphasis> < 0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference,<Emphasis Type="Italic">P</Emphasis> > 0.05; (3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (<Emphasis Type="Italic">P</Emphasis> < 0. 05).<Emphasis Type="Bold">Conclusion</Emphasis>: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.</Para></Abstract><KeywordGroup Language="En"><Heading>Key Words</Heading><Keyword>severe acute respiratory syndrome</Keyword><Keyword>integrative Chinese and western medicine treatment</Keyword><Keyword>corticosteroid</Keyword><Keyword>clinical study</Keyword></KeywordGroup><ArticleNote Type="Misc"><SimplePara>The study is supporded by The Ministry of Science and Technology of 863 Programme “The Developing the Key of Technique and Products for Preventing SARS” (No. 2003AA208101)</SimplePara></ArticleNote></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Jiao</namePart><namePart type="family">Qiang</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><affiliation>E-mail: jiaoqiang@263.net</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wang</namePart><namePart type="family">Biao</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Zhang</namePart><namePart type="family">Rui-lin</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wang</namePart><namePart type="family">Bao-guo</namePart><affiliation>Beijing Tiantan Hospital, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Feng</namePart><namePart type="family">Li-min</namePart><affiliation>Beijing Tiantan Hospital, China</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wang</namePart><namePart type="family">Hai-jian</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Luo</namePart><namePart type="family">Yan-nan</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yan</namePart><namePart type="family">Xiong</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Shen</namePart><namePart type="family">Hong-qiang</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ma</namePart><namePart type="family">Ying-min</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Xiong</namePart><namePart type="family">Yun</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Chen</namePart><namePart type="family">Wei-heng</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ma</namePart><namePart type="family">Da</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Cheng</namePart><namePart type="family">Ting</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Zhou</namePart><namePart type="family">Wei</namePart><affiliation>Wangjing Hospital, China Academy of Traditional Chinese Medicine, 100102, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><place><placeTerm type="text">Beijing</placeTerm></place><dateCreated encoding="w3cdtf">2003-06-26</dateCreated><dateIssued encoding="w3cdtf">2003-09-01</dateIssued><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Objective: To evaluate the efficacy of integrative Chinese and western medicine (ICWM) in treating severe acute respiratory syndrome (SARS) patients.Methods: Through parallel control design, 49 SARS patients were observed. Used as control, there were in the western medicine (WM) group 29 patients, who were treated with Ribavirin, Levofloxacin, Thymopentin, Azithromycin, methylprednisolone, etc., on the basis of “Recommended Protocol for Infectious Atypical Pneumonia” (abbreviated as “Recommended Protocol”) issueed by Ministry of Health. As the treated group, there were in the ICWM 20 cases. The protocol for treatment of SARS in “Special Science and Technological Action to Prevent and Treat SARS” (abbreviated as “Special S-T Action”), issued by Ministry of Science and Technology, together with the same WM as those for the control group.Results: (1) Time from the disease onset to the symptom improvement were 5.10±2. 83 days and 7. 62±2. 27 days in ICWM and WM group respectively,P < 0.05; (2) As to corticosteroid (CS) amount and days before reducing dosage, 2 groups showed no significant difference,P > 0.05; (3) There was no significant difference in the time from disease onset to the body temperature normalization and the total amount of CS and the duration of using CS before reducing it to 80 mg between the ICWM group and the WM group; (4) The days and amounts for use CS after reducing between the ICWM group and the WM group were significantly different (P < 0. 05).Conclusion: There were obvious advantages in ICWM to treat SARS, compared with that of WM alone, especially in improving the clinical symptoms, promoting the recovery of immune function, promoting the absorption of pulmonary inflammation and reducing the dosage and duration of CS treatment.</abstract><note>Original Artical</note><subject lang="en"><genre>Key Words</genre><topic>severe acute respiratory syndrome</topic><topic>integrative Chinese and western medicine treatment</topic><topic>corticosteroid</topic><topic>clinical study</topic></subject><relatedItem type="host"><titleInfo><title>Chinese Journal of Integrative Medicine</title></titleInfo><titleInfo type="abbreviated"><title>Chin. 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