Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine
Identifieur interne : 000A27 ( Istex/Corpus ); précédent : 000A26; suivant : 000A28Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine
Auteurs : Zou Jin-Pan ; Hua Bao-Jin ; Chen Chang-Huai ; Xu Gui-Cheng ; Su Hao ; Wang Yin ; Li Guang-Xi ; Yang Zong-Yan ; He Xia-Xiu ; Liu Xi-Ming ; Ni Qing ; Li Hui ; Zhao Hong ; Zhang Li-Na ; Wang Wei-DongSource :
- Chinese Journal of Integrative Medicine [ 1672-0415 ] ; 2003-09-01.
English descriptors
- KwdEn :
Abstract
Abstract: Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM.Results: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in 42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST), 47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr); in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD3 and 76. 5% (26/34 patients) lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45. 2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial enzyme and renal function all normalized. However, of the 30 patients who had CD3 reexamination, 70% of the CD3 showed lower than normal range and 36. 7% showed their CD4/CD8 inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine (WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.Conclusion: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage and its subsets, CD3 and CD4 /CD8 ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial to remit partial symptoms and promote rehabilitation.
Url:
DOI: 10.1007/BF02838025
Links to Exploration step
ISTEX:1686881899A9DDE1A16AD41B01A695AA07825295Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title><author><name sortKey="Jin Pan, Zou" sort="Jin Pan, Zou" uniqKey="Jin Pan Z" first="Zou" last="Jin-Pan">Zou Jin-Pan</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: zjp2008@sina.com</mods:affiliation></affiliation></author><author><name sortKey="Bao Jin, Hua" sort="Bao Jin, Hua" uniqKey="Bao Jin H" first="Hua" last="Bao-Jin">Hua Bao-Jin</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Chang Huai, Chen" sort="Chang Huai, Chen" uniqKey="Chang Huai C" first="Chen" last="Chang-Huai">Chen Chang-Huai</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Gui Cheng, Xu" sort="Gui Cheng, Xu" uniqKey="Gui Cheng X" first="Xu" last="Gui-Cheng">Xu Gui-Cheng</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hao, Su" sort="Hao, Su" uniqKey="Hao S" first="Su" last="Hao">Su Hao</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Yin, Wang" sort="Yin, Wang" uniqKey="Yin W" first="Wang" last="Yin">Wang Yin</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Guang Xi, Li" sort="Guang Xi, Li" uniqKey="Guang Xi L" first="Li" last="Guang-Xi">Li Guang-Xi</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Zong Yan, Yang" sort="Zong Yan, Yang" uniqKey="Zong Yan Y" first="Yang" last="Zong-Yan">Yang Zong-Yan</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Xia Xiu, He" sort="Xia Xiu, He" uniqKey="Xia Xiu H" first="He" last="Xia-Xiu">He Xia-Xiu</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Xi Ming, Liu" sort="Xi Ming, Liu" uniqKey="Xi Ming L" first="Liu" last="Xi-Ming">Liu Xi-Ming</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Qing, Ni" sort="Qing, Ni" uniqKey="Qing N" first="Ni" last="Qing">Ni Qing</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hui, Li" sort="Hui, Li" uniqKey="Hui L" first="Li" last="Hui">Li Hui</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hong, Zhao" sort="Hong, Zhao" uniqKey="Hong Z" first="Zhao" last="Hong">Zhao Hong</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Li Na, Zhang" sort="Li Na, Zhang" uniqKey="Li Na Z" first="Zhang" last="Li-Na">Zhang Li-Na</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Wei Dong, Wang" sort="Wei Dong, Wang" uniqKey="Wei Dong W" first="Wang" last="Wei-Dong">Wang Wei-Dong</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:1686881899A9DDE1A16AD41B01A695AA07825295</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1007/BF02838025</idno><idno type="url">https://api.istex.fr/ark:/67375/VQC-FFWTJ773-F/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000A27</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000A27</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title><author><name sortKey="Jin Pan, Zou" sort="Jin Pan, Zou" uniqKey="Jin Pan Z" first="Zou" last="Jin-Pan">Zou Jin-Pan</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: zjp2008@sina.com</mods:affiliation></affiliation></author><author><name sortKey="Bao Jin, Hua" sort="Bao Jin, Hua" uniqKey="Bao Jin H" first="Hua" last="Bao-Jin">Hua Bao-Jin</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Chang Huai, Chen" sort="Chang Huai, Chen" uniqKey="Chang Huai C" first="Chen" last="Chang-Huai">Chen Chang-Huai</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Gui Cheng, Xu" sort="Gui Cheng, Xu" uniqKey="Gui Cheng X" first="Xu" last="Gui-Cheng">Xu Gui-Cheng</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hao, Su" sort="Hao, Su" uniqKey="Hao S" first="Su" last="Hao">Su Hao</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Yin, Wang" sort="Yin, Wang" uniqKey="Yin W" first="Wang" last="Yin">Wang Yin</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Guang Xi, Li" sort="Guang Xi, Li" uniqKey="Guang Xi L" first="Li" last="Guang-Xi">Li Guang-Xi</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Zong Yan, Yang" sort="Zong Yan, Yang" uniqKey="Zong Yan Y" first="Yang" last="Zong-Yan">Yang Zong-Yan</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Xia Xiu, He" sort="Xia Xiu, He" uniqKey="Xia Xiu H" first="He" last="Xia-Xiu">He Xia-Xiu</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Xi Ming, Liu" sort="Xi Ming, Liu" uniqKey="Xi Ming L" first="Liu" last="Xi-Ming">Liu Xi-Ming</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Qing, Ni" sort="Qing, Ni" uniqKey="Qing N" first="Ni" last="Qing">Ni Qing</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hui, Li" sort="Hui, Li" uniqKey="Hui L" first="Li" last="Hui">Li Hui</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Hong, Zhao" sort="Hong, Zhao" uniqKey="Hong Z" first="Zhao" last="Hong">Zhao Hong</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Li Na, Zhang" sort="Li Na, Zhang" uniqKey="Li Na Z" first="Zhang" last="Li-Na">Zhang Li-Na</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author><author><name sortKey="Wei Dong, Wang" sort="Wei Dong, Wang" uniqKey="Wei Dong W" first="Wang" last="Wei-Dong">Wang Wei-Dong</name><affiliation><mods:affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Chinese Journal of Integrative Medicine</title><title level="j" type="abbrev">Chin. J. Integr. Med.</title><idno type="ISSN">1672-0415</idno><idno type="eISSN">1993-0402</idno><imprint><publisher>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><pubPlace>Beijing</pubPlace><date type="published" when="2003-09-01">2003-09-01</date><biblScope unit="volume">9</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="169">169</biblScope><biblScope unit="page" to="174">174</biblScope></imprint><idno type="ISSN">1672-0415</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1672-0415</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>clinical characteristics</term><term>integrative Chinese and western medical treatment</term><term>severe acute respiratory syndrome</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM.Results: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in 42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST), 47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr); in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD3 and 76. 5% (26/34 patients) lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45. 2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial enzyme and renal function all normalized. However, of the 30 patients who had CD3 reexamination, 70% of the CD3 showed lower than normal range and 36. 7% showed their CD4/CD8 inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine (WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.Conclusion: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage and its subsets, CD3 and CD4 /CD8 ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial to remit partial symptoms and promote rehabilitation.</div></front></TEI><istex><corpusName>springer-journals</corpusName><author><json:item><name>Zou Jin-pan</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string><json:string>E-mail: zjp2008@sina.com</json:string></affiliations></json:item><json:item><name>Hua Bao-jin</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Chen Chang-huai</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Xu Gui-cheng</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Su Hao</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Wang Yin</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Li Guang-xi</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Yang Zong-yan</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>He Xia-xiu</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Liu Xi-ming</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Ni Qing</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Li Hui</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Zhao Hong</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Zhang Li-na</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item><json:item><name>Wang Wei-dong</name><affiliations><json:string>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>severe acute respiratory syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>clinical characteristics</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>integrative Chinese and western medical treatment</value></json:item></subject><articleId><json:string>BF02838025</json:string><json:string>Art2</json:string></articleId><arkIstex>ark:/67375/VQC-FFWTJ773-F</arkIstex><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM.Results: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in 42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST), 47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr); in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD3 and 76. 5% (26/34 patients) lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45. 2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial enzyme and renal function all normalized. However, of the 30 patients who had CD3 reexamination, 70% of the CD3 showed lower than normal range and 36. 7% showed their CD4/CD8 inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine (WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.Conclusion: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage and its subsets, CD3 and CD4 /CD8 ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial to remit partial symptoms and promote rehabilitation.</abstract><qualityIndicators><score>8.099</score><pdfWordCount>3099</pdfWordCount><pdfCharCount>18619</pdfCharCount><pdfVersion>1.3</pdfVersion><pdfPageCount>6</pdfPageCount><pdfPageSize>590.424 x 806.424 pts</pdfPageSize><refBibsNative>false</refBibsNative><abstractWordCount>433</abstractWordCount><abstractCharCount>2614</abstractCharCount><keywordCount>3</keywordCount></qualityIndicators><title>Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title><genre><json:string>research-article</json:string></genre><host><title>Chinese Journal of Integrative Medicine</title><language><json:string>unknown</json:string></language><publicationDate>2003</publicationDate><copyrightDate>2003</copyrightDate><issn><json:string>1672-0415</json:string></issn><eissn><json:string>1993-0402</json:string></eissn><journalId><json:string>11655</json:string></journalId><volume>9</volume><issue>3</issue><pages><first>169</first><last>174</last></pages><genre><json:string>journal</json:string></genre><subject><json:item><value>Medicine & Public Health</value></json:item><json:item><value>Medicine/Public Health, general</value></json:item></subject></host><ark><json:string>ark:/67375/VQC-FFWTJ773-F</json:string></ark><publicationDate>2003</publicationDate><copyrightDate>2003</copyrightDate><doi><json:string>10.1007/BF02838025</json:string></doi><id>1686881899A9DDE1A16AD41B01A695AA07825295</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-FFWTJ773-F/fulltext.pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-FFWTJ773-F/bundle.zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/ark:/67375/VQC-FFWTJ773-F/fulltext.tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher scheme="https://scientific-publisher.data.istex.fr">Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><pubPlace>Beijing</pubPlace><availability><licence><p>The Chinese Journal of Integrated Traditional and Western Medicine Press, 2003</p></licence><p scheme="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</p></availability><date>2003-06-04</date></publicationStmt><notesStmt><note type="research-article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</note><note type="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note><note>Original Articles</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title><author xml:id="author-0000" corresp="yes"><persName><forename type="first">Zou</forename><surname>Jin-pan</surname></persName><email>zjp2008@sina.com</email><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0001"><persName><forename type="first">Hua</forename><surname>Bao-jin</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0002"><persName><forename type="first">Chen</forename><surname>Chang-huai</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0003"><persName><forename type="first">Xu</forename><surname>Gui-cheng</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0004"><persName><forename type="first">Su</forename><surname>Hao</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0005"><persName><forename type="first">Wang</forename><surname>Yin</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0006"><persName><forename type="first">Li</forename><surname>Guang-xi</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0007"><persName><forename type="first">Yang</forename><surname>Zong-yan</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0008"><persName><forename type="first">He</forename><surname>Xia-xiu</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0009"><persName><forename type="first">Liu</forename><surname>Xi-ming</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0010"><persName><forename type="first">Ni</forename><surname>Qing</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0011"><persName><forename type="first">Li</forename><surname>Hui</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0012"><persName><forename type="first">Zhao</forename><surname>Hong</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0013"><persName><forename type="first">Zhang</forename><surname>Li-na</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><author xml:id="author-0014"><persName><forename type="first">Wang</forename><surname>Wei-dong</surname></persName><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation></author><idno type="istex">1686881899A9DDE1A16AD41B01A695AA07825295</idno><idno type="ark">ark:/67375/VQC-FFWTJ773-F</idno><idno type="DOI">10.1007/BF02838025</idno><idno type="article-id">BF02838025</idno><idno type="article-id">Art2</idno></analytic><monogr><title level="j">Chinese Journal of Integrative Medicine</title><title level="j" type="abbrev">Chin. J. Integr. Med.</title><idno type="pISSN">1672-0415</idno><idno type="eISSN">1993-0402</idno><idno type="journal-ID">true</idno><idno type="issue-article-count">24</idno><idno type="volume-issue-count">4</idno><imprint><publisher>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><pubPlace>Beijing</pubPlace><date type="published" when="2003-09-01"></date><biblScope unit="volume">9</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="169">169</biblScope><biblScope unit="page" to="174">174</biblScope></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2003-06-04</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM.Results: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in 42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST), 47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr); in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD3 and 76. 5% (26/34 patients) lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45. 2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial enzyme and renal function all normalized. However, of the 30 patients who had CD3 reexamination, 70% of the CD3 showed lower than normal range and 36. 7% showed their CD4/CD8 inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine (WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.Conclusion: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage and its subsets, CD3 and CD4 /CD8 ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial to remit partial symptoms and promote rehabilitation.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Key Words</head><item><term>severe acute respiratory syndrome</term></item><item><term>clinical characteristics</term></item><item><term>integrative Chinese and western medical treatment</term></item></list></keywords></textClass><textClass><keywords scheme="Journal-Subject-Group"><list><label>H</label><item><term>Medicine & Public Health</term></item><label>H00007</label><item><term>Medicine/Public Health, general</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2003-06-04">Created</change><change when="2003-09-01">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-FFWTJ773-F/fulltext.txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus springer-journals not found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</PublisherName><PublisherLocation>Beijing</PublisherLocation></PublisherInfo><Journal><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>11655</JournalID><JournalPrintISSN>1672-0415</JournalPrintISSN><JournalElectronicISSN>1993-0402</JournalElectronicISSN><JournalTitle>Chinese Journal of Integrative Medicine</JournalTitle><JournalAbbreviatedTitle>Chin. J. Integr. Med.</JournalAbbreviatedTitle><JournalSubjectGroup><JournalSubject Type="Primary" Code="H">Medicine & Public Health</JournalSubject><JournalSubject Type="Secondary" Priority="1" Code="H00007">Medicine/Public Health, general</JournalSubject></JournalSubjectGroup></JournalInfo><Volume><VolumeInfo VolumeType="Regular" TocLevels="0"><VolumeIDStart>9</VolumeIDStart><VolumeIDEnd>9</VolumeIDEnd><VolumeIssueCount>4</VolumeIssueCount></VolumeInfo><Issue IssueType="Regular"><IssueInfo TocLevels="0"><IssueIDStart>3</IssueIDStart><IssueIDEnd>3</IssueIDEnd><IssueArticleCount>24</IssueArticleCount><IssueHistory><CoverDate><Year>2003</Year><Month>9</Month></CoverDate></IssueHistory><IssueCopyright><CopyrightHolderName>The Chinese Journal of Integrated Traditional and Western Medicine Press</CopyrightHolderName><CopyrightYear>2003</CopyrightYear></IssueCopyright></IssueInfo><Article ID="Art2"><ArticleInfo Language="En" ArticleType="OriginalPaper" NumberingStyle="Unnumbered" TocLevels="0" ContainsESM="No"><ArticleID>BF02838025</ArticleID><ArticleDOI>10.1007/BF02838025</ArticleDOI><ArticleSequenceNumber>2</ArticleSequenceNumber><ArticleTitle Language="En">Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</ArticleTitle><ArticleCategory>Original Articles</ArticleCategory><ArticleFirstPage>169</ArticleFirstPage><ArticleLastPage>174</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2008</Year><Month>2</Month><Day>15</Day></RegistrationDate><Received><Year>2003</Year><Month>6</Month><Day>4</Day></Received></ArticleHistory><ArticleCopyright><CopyrightHolderName>The Chinese Journal of Integrated Traditional and Western Medicine Press</CopyrightHolderName><CopyrightYear>2003</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants><ArticleContext><JournalID>11655</JournalID><VolumeIDStart>9</VolumeIDStart><VolumeIDEnd>9</VolumeIDEnd><IssueIDStart>3</IssueIDStart><IssueIDEnd>3</IssueIDEnd></ArticleContext></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Zou</GivenName><FamilyName>Jin-pan</FamilyName></AuthorName><Contact><Phone>010-88001019</Phone><Email>zjp2008@sina.com</Email></Contact></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Hua</GivenName><FamilyName>Bao-jin</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Chen</GivenName><FamilyName>Chang-huai</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Xu</GivenName><FamilyName>Gui-cheng</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Su</GivenName><FamilyName>Hao</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Wang</GivenName><FamilyName>Yin</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Li</GivenName><FamilyName>Guang-xi</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Yang</GivenName><FamilyName>Zong-yan</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>He</GivenName><FamilyName>Xia-xiu</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Liu</GivenName><FamilyName>Xi-ming</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Ni</GivenName><FamilyName>Qing</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Li</GivenName><FamilyName>Hui</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Zhao</GivenName><FamilyName>Hong</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Zhang</GivenName><FamilyName>Li-na</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Wang</GivenName><FamilyName>Wei-dong</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Guang’anmen Hospital</OrgDivision><OrgName>China Academy of TCM</OrgName><OrgAddress><Postcode>100053</Postcode><City>Beijing</City></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para><Emphasis Type="Bold">Objective</Emphasis>: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).<Emphasis Type="Bold">Methods</Emphasis>: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM.<Emphasis Type="Bold">Results</Emphasis>: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in 42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST), 47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr); in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD<Subscript>3</Subscript> and 76. 5% (26/34 patients) lowered CD<Subscript>4</Subscript>/CD<Subscript>8</Subscript> ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45. 2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial enzyme and renal function all normalized. However, of the 30 patients who had CD<Subscript>3</Subscript> reexamination, 70% of the CD<Subscript>3</Subscript> showed lower than normal range and 36. 7% showed their CD<Subscript>4</Subscript>/CD<Subscript>8</Subscript> inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine (WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.<Emphasis Type="Bold">Conclusion</Emphasis>: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage and its subsets, CD<Subscript>3</Subscript> and CD<Subscript>4</Subscript> /CD<Subscript>8</Subscript> ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial to remit partial symptoms and promote rehabilitation.</Para></Abstract><KeywordGroup Language="En"><Heading>Key Words</Heading><Keyword>severe acute respiratory syndrome</Keyword><Keyword>clinical characteristics</Keyword><Keyword>integrative Chinese and western medical treatment</Keyword></KeywordGroup></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine</title></titleInfo><name type="personal" displayLabel="corresp"><namePart type="given">Zou</namePart><namePart type="family">Jin-pan</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><affiliation>E-mail: zjp2008@sina.com</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Hua</namePart><namePart type="family">Bao-jin</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Chen</namePart><namePart type="family">Chang-huai</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Xu</namePart><namePart type="family">Gui-cheng</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Su</namePart><namePart type="family">Hao</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wang</namePart><namePart type="family">Yin</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Li</namePart><namePart type="family">Guang-xi</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Yang</namePart><namePart type="family">Zong-yan</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">He</namePart><namePart type="family">Xia-xiu</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Liu</namePart><namePart type="family">Xi-ming</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Ni</namePart><namePart type="family">Qing</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Li</namePart><namePart type="family">Hui</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Zhao</namePart><namePart type="family">Hong</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Zhang</namePart><namePart type="family">Li-na</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Wang</namePart><namePart type="family">Wei-dong</namePart><affiliation>Guang’anmen Hospital, China Academy of TCM, 100053, Beijing</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-1JC4F85T-7">research-article</genre><originInfo><publisher>Chinese Association of Traditional and Western Medicine, China Academy of Chinese Medical Sciences</publisher><place><placeTerm type="text">Beijing</placeTerm></place><dateCreated encoding="w3cdtf">2003-06-04</dateCreated><dateIssued encoding="w3cdtf">2003-09-01</dateIssued><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><abstract lang="en">Abstract: Objective: To understand the clinical manifestation of severe acute respiratory syndrome (SARS) and explore its effective treatment with integrative Chinese and western medicine (ICWM).Methods: The data of patients, whose diagnosis of SARS had been confirmed were summarized and analyzed, and clinical observation was conducted when the patients were treated with ICWM.Results: In the early stage of the 42 patients, the symptoms revealed were fever in 100% of SARS patients, headache in 92. 9%, aversion to cold in 76. 2%, chest stuffiness in 76. 2%, cough in 73. 8% and myalgia in 88. 1%; pulmonary lesion involves ≥3 lobes in 42. 9%, 2 lobes in 47. 6% and 1 lobe in 9. 5%; 61. 9% of them showed liver function abnormality (increase of ALT or AST), 47. 6% showed elevated myocardial enzyme (CK or CK-MB), 0. 48% showed an inclination of renal function (higher of BUN or Cr); in their T lymphocyte subsets, 91. 2% (31/34 patients) had lowered CD3 and 76. 5% (26/34 patients) lowered CD4/CD8 ratio. In the mid-late stage, the symptoms were lassitude and weakness in 85. 7%, scare in 81. 0%, short of breath or chest stuffiness in 71. 4%, loss of appetite in 64. 3%; light dark tongue proper in 52.4%, yellow and white tongue coating in 45. 2%, and yellow thick coating on the middle-root part of the tongue in 21. 4%. Most of them were asymptomatic when discharged from hospital, with 92. 8% of their pulmonary lesion, according to chest film, completely absorbed and liver function, myocardial enzyme and renal function all normalized. However, of the 30 patients who had CD3 reexamination, 70% of the CD3 showed lower than normal range and 36. 7% showed their CD4/CD8 inclined to lower margin, follow-up should be done for these patients. Of the 42 patients, who received western medicine (WM) alone in the early stage and ICWM in the mid-late stage, 10 were severe cases and 3 critical cases, but none of them died. The mean defervescent time was 3. 52±0. 85 days, the time for complete absorption of pulmonary lesion judged by chest X-ray film was 26. 82±5. 98 days, and the mean hospitalization time was 33. 60±4. 37 days.Conclusion: The manifestation of SARS is multifarious, showing that there were damage in multiple organs. The T lymphocyte count percentage and its subsets, CD3 and CD4 /CD8 ratio, are valuable for early diagnosis and follow-up in the rehabilitation stage. Majority of the patients could be clinically cured. Combined treatment of WM and TCM according to syndrome differentiation and psychiatric intervention are beneficial to remit partial symptoms and promote rehabilitation.</abstract><note>Original Articles</note><subject lang="en"><genre>Key Words</genre><topic>severe acute respiratory syndrome</topic><topic>clinical characteristics</topic><topic>integrative Chinese and western medical treatment</topic></subject><relatedItem type="host"><titleInfo><title>Chinese Journal of Integrative Medicine</title></titleInfo><titleInfo type="abbreviated"><title>Chin. J. Integr. Med.</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><originInfo><publisher>Springer</publisher><dateIssued encoding="w3cdtf">2003-09-01</dateIssued><copyrightDate encoding="w3cdtf">2003</copyrightDate></originInfo><subject><genre>Journal-Subject-Group</genre><topic authority="SpringerSubjectCodes" authorityURI="H">Medicine & Public Health</topic><topic authority="SpringerSubjectCodes" authorityURI="H00007">Medicine/Public Health, general</topic></subject><identifier type="ISSN">1672-0415</identifier><identifier type="eISSN">1993-0402</identifier><identifier type="JournalID">11655</identifier><identifier type="IssueArticleCount">24</identifier><identifier type="VolumeIssueCount">4</identifier><part><date>2003</date><detail type="volume"><number>9</number><caption>vol.</caption></detail><detail type="issue"><number>3</number><caption>no.</caption></detail><extent unit="pages"><start>169</start><end>174</end></extent></part><recordInfo><recordOrigin>The Chinese Journal of Integrated Traditional and Western Medicine Press, 2003</recordOrigin></recordInfo></relatedItem><identifier type="istex">1686881899A9DDE1A16AD41B01A695AA07825295</identifier><identifier type="ark">ark:/67375/VQC-FFWTJ773-F</identifier><identifier type="DOI">10.1007/BF02838025</identifier><identifier type="ArticleID">BF02838025</identifier><identifier type="ArticleID">Art2</identifier><accessCondition type="use and reproduction" contentType="copyright">The Chinese Journal of Integrated Traditional and Western Medicine Press, 2003</accessCondition><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-3XSW68JL-F">springer</recordContentSource><recordOrigin>The Chinese Journal of Integrated Traditional and Western Medicine Press, 2003</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/ark:/67375/VQC-FFWTJ773-F/record.json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000A27 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000A27 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:1686881899A9DDE1A16AD41B01A695AA07825295
|texte= Clinical characteristics of 42 SARS patients and their treatment of integrative Chinese and western medicine
}}
| This area was generated with Dilib version V0.6.33. |  |