Clinical Characteristics of Upper Gastrointestinal Bleeding in Hemodialysis Patients
Identifieur interne : 002015 ( Istex/Checkpoint ); précédent : 002014; suivant : 002016Clinical Characteristics of Upper Gastrointestinal Bleeding in Hemodialysis Patients
Auteurs : B. K. Bang [Corée du Sud] ; Y. O. Kim [Corée du Sud] ; Y. S. Kim [Corée du Sud] ; Y. S. Shin [Corée du Sud] ; H. S. Chae [Corée du Sud] ; Y. S. Shin [Corée du Sud] ; S. A. Yoon [Corée du Sud] ; C. W. Yang [Corée du Sud] ; Y. S. Kim [Corée du Sud] ; Y. S. Chang [Corée du Sud]Source :
- Hemodialysis International [ 1492-7535 ] ; 2004-01.
Abstract
Upper gastrointestinal bleeding (UGIB) frequently occurs in hemodialysis (HD) patients. But, clinical characteristics of UGIB in HD patients are not well reported yet. Objective: This study was designed to compare the clinical characteristics of UGIB between HD patients and normal population with intact renal function. Methods: This study enrolled 24 HD patients with UGIB. Age‐ and sex‐matched 26 patients with UGIB and normal renal function were selected as control group during the same period. Of the cases with UGIB, esophageal variceal bleedings due to liver cirrhosis were excluded in this study. We investigated the results of treatment and UGIB‐associated mortality for 3 months after the event and then compared previous gastrointestinal (GI) symptoms (Sx), endoscopic findings, treatment results, and mortality between HD patients and control. Results: The results are summarized in the table. HD patients (n = 24) Control (n = 26) p value Age (years) 60±11 61±11 0.702 Sex [male/female (%)] 62.5/37.5 53.8/46.2 0.536 Previous GI Sx
[asymptomatic/
symptomatic (%)] 33.3/66.7 65.3/34.7 0.024 Endoscopic diagnosis
[vascular ectasia/others (%)] 45.8/54.2 15.3/84.7 0.020 Primary treatment
[endoscopic/medical (%)] 70.8/29.2 61.5/38.5 0.488 Results of treatment Success/rebleeding (%) 75.0/25.0 92.4/7.6 0.095 Patient survival/UGIB‐
related death (%) 83.3/16.7 100/0 0.046 Conclusion: Previous gastrointestinal symptoms were less frequent in HD patients than normal population with intact renal function. In contrast, HD patients had higher incidence of vascular ectasia and mortality than normal population with intact renal function.
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DOI: 10.1111/j.1492-7535.2004.0085ac.x
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<front><div type="abstract" xml:lang="en">Upper gastrointestinal bleeding (UGIB) frequently occurs in hemodialysis (HD) patients. But, clinical characteristics of UGIB in HD patients are not well reported yet. Objective: This study was designed to compare the clinical characteristics of UGIB between HD patients and normal population with intact renal function. Methods: This study enrolled 24 HD patients with UGIB. Age‐ and sex‐matched 26 patients with UGIB and normal renal function were selected as control group during the same period. Of the cases with UGIB, esophageal variceal bleedings due to liver cirrhosis were excluded in this study. We investigated the results of treatment and UGIB‐associated mortality for 3 months after the event and then compared previous gastrointestinal (GI) symptoms (Sx), endoscopic findings, treatment results, and mortality between HD patients and control. Results: The results are summarized in the table. HD patients (n = 24) Control (n = 26) p value Age (years) 60±11 61±11 0.702 Sex [male/female (%)] 62.5/37.5 53.8/46.2 0.536 Previous GI Sx
[asymptomatic/
symptomatic (%)] 33.3/66.7 65.3/34.7 0.024 Endoscopic diagnosis
[vascular ectasia/others (%)] 45.8/54.2 15.3/84.7 0.020 Primary treatment
[endoscopic/medical (%)] 70.8/29.2 61.5/38.5 0.488 Results of treatment Success/rebleeding (%) 75.0/25.0 92.4/7.6 0.095 Patient survival/UGIB‐
related death (%) 83.3/16.7 100/0 0.046 Conclusion: Previous gastrointestinal symptoms were less frequent in HD patients than normal population with intact renal function. In contrast, HD patients had higher incidence of vascular ectasia and mortality than normal population with intact renal function.</div>
</front>
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