SrasV1, Hal, Corpus, bibRecord, 000178

Type 1 interferons as a potential treatment against COVID-19

Identifieur interne : 000178 ( Hal/Corpus ); précédent : 000177; suivant : 000179

Type 1 interferons as a potential treatment against COVID-19

Auteurs : Erwan Sallard ; François-Xavier Lescure ; Yazdan Yazdanpanah ; France Mentré ; Nathan Peiffer-Smadja

Source :

Antiviral Research [ 0166-3542 ] ; 2020-04-07.

RBID : Hal:inserm-02546137

English descriptors

mix :
- COVID-19, Interferon, SARS-CoV-2.

Abstract

Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.

Url:

https://www.hal.inserm.fr/inserm-02546137

DOI: 10.1016/j.antiviral.2020.104791

Links to Exploration step

Hal:inserm-02546137

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Type 1 interferons as a potential treatment against COVID-19</title>
<author><name sortKey="Sallard, Erwan" sort="Sallard, Erwan" uniqKey="Sallard E" first="Erwan" last="Sallard">Erwan Sallard</name>
<affiliation><hal:affiliation type="institution" xml:id="struct-59704" status="VALID">          <orgName>École normale supérieure - Paris</orgName>
          <orgName type="acronym">ENS Paris</orgName>
          <desc>            <address>              <addrLine>45, Rue d'Ulm - 75230 Paris cedex 05</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.ens.fr</ref>
          </desc>
        </hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Lescure, Francois Xavier" sort="Lescure, Francois Xavier" uniqKey="Lescure F" first="François-Xavier" last="Lescure">François-Xavier Lescure</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Yazdanpanah, Yazdan" sort="Yazdanpanah, Yazdan" uniqKey="Yazdanpanah Y" first="Yazdan" last="Yazdanpanah">Yazdan Yazdanpanah</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Mentre, France" sort="Mentre, France" uniqKey="Mentre F" first="France" last="Mentré">France Mentré</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Peiffer Smadja, Nathan" sort="Peiffer Smadja, Nathan" uniqKey="Peiffer Smadja N" first="Nathan" last="Peiffer-Smadja">Nathan Peiffer-Smadja</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:inserm-02546137</idno>
<idno type="halId">inserm-02546137</idno>
<idno type="halUri">https://www.hal.inserm.fr/inserm-02546137</idno>
<idno type="url">https://www.hal.inserm.fr/inserm-02546137</idno>
<idno type="doi">10.1016/j.antiviral.2020.104791</idno>
<date when="2020-04-07">2020-04-07</date>
<idno type="wicri:Area/Hal/Corpus">000178</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Type 1 interferons as a potential treatment against COVID-19</title>
<author><name sortKey="Sallard, Erwan" sort="Sallard, Erwan" uniqKey="Sallard E" first="Erwan" last="Sallard">Erwan Sallard</name>
<affiliation><hal:affiliation type="institution" xml:id="struct-59704" status="VALID">          <orgName>École normale supérieure - Paris</orgName>
          <orgName type="acronym">ENS Paris</orgName>
          <desc>            <address>              <addrLine>45, Rue d'Ulm - 75230 Paris cedex 05</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.ens.fr</ref>
          </desc>
        </hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Lescure, Francois Xavier" sort="Lescure, Francois Xavier" uniqKey="Lescure F" first="François-Xavier" last="Lescure">François-Xavier Lescure</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Yazdanpanah, Yazdan" sort="Yazdanpanah, Yazdan" uniqKey="Yazdanpanah Y" first="Yazdan" last="Yazdanpanah">Yazdan Yazdanpanah</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Mentre, France" sort="Mentre, France" uniqKey="Mentre F" first="France" last="Mentré">France Mentré</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
<author><name sortKey="Peiffer Smadja, Nathan" sort="Peiffer Smadja, Nathan" uniqKey="Peiffer Smadja N" first="Nathan" last="Peiffer-Smadja">Nathan Peiffer-Smadja</name>
<affiliation><hal:affiliation type="laboratory" xml:id="struct-1005021" status="VALID">          <idno type="IdRef">235514829</idno>
          <idno type="RNSR">201420743R</idno>
          <orgName>Infection, Anti-microbiens, Modélisation, Evolution</orgName>
          <orgName type="acronym">IAME (UMR_S_1137 / U1137)</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>Faculté de médecine Paris Diderot Paris 7 - site Bichat - 16 rue Henri Huchard 75890 Paris Cedex 18</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.iame-research.center/</ref>
          </desc>
          <listRelation>            <relation active="#struct-303171" type="direct"></relation>
            <relation name="U1137" active="#struct-303623" type="direct"></relation>
            <relation name="UMR_S_1137" active="#struct-557826" type="direct"></relation>
            <relation active="#struct-581146" type="direct"></relation>
          </listRelation>
        <tutelles><tutelle active="#struct-303171" type="direct"><org type="regroupinstitution" xml:id="struct-303171" status="VALID">          <orgName>Université Sorbonne Paris Cité</orgName>
          <orgName type="acronym">USPC</orgName>
          <date type="start">2010</date>
          <desc>            <address>              <addrLine>Université Sorbonne Paris Cité | 100-104, avenue de France | 75013 Paris</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.sorbonne-paris-cite.fr/fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="U1137" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID">          <idno type="IdRef">026388278</idno>
          <orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
          <orgName type="acronym">INSERM</orgName>
          <desc>            <address>              <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">http://www.inserm.fr</ref>
          </desc>
        </org>
</tutelle>
<tutelle name="UMR_S_1137" active="#struct-557826" type="direct"><org type="institution" xml:id="struct-557826" status="VALID">          <orgName>Université de Paris</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <country key="FR"></country>
            </address>
          </desc>
        </org>
</tutelle>
<tutelle active="#struct-581146" type="direct"><org type="institution" xml:id="struct-581146" status="VALID">          <orgName>Université Sorbonne Paris Nord</orgName>
          <date type="start">2020-01-01</date>
          <desc>            <address>              <addrLine>99, avenue Jean-Baptiste Clément, 93430 Villetaneuse</addrLine>
              <country key="FR"></country>
            </address>
            <ref type="url">https://www.univ-paris13.fr/</ref>
          </desc>
        </org>
</tutelle>
</tutelles>
</hal:affiliation>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.antiviral.2020.104791</idno>
<series><title level="j">Antiviral Research</title>
<idno type="ISSN">0166-3542</idno>
<imprint><date type="datePub">2020-04-07</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>COVID-19</term>
<term>Interferon</term>
<term>SARS-CoV-2</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">              <p>Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.</p>
            </div>
</front>
</TEI>
<hal api="V3">          <titleStmt>            <title xml:lang="en">Type 1 interferons as a potential treatment against COVID-19</title>
            <author role="aut">              <persName>                <forename type="first">Erwan</forename>
                <surname>Sallard</surname>
              </persName>
              <idno type="halauthorid">11800961</idno>
              <affiliation ref="#struct-59704"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">François-Xavier</forename>
                <surname>Lescure</surname>
              </persName>
              <idno type="halauthorid">957302</idno>
              <affiliation ref="#struct-1005021"></affiliation>
              <affiliation ref="#struct-487836"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">Yazdan</forename>
                <surname>Yazdanpanah</surname>
              </persName>
              <email type="md5">1171907f9f9de83a6d897c88c99cf2ac</email>
              <email type="domain">bch.aphp.fr</email>
              <idno type="halauthorid">848920</idno>
              <affiliation ref="#struct-1005021"></affiliation>
              <affiliation ref="#struct-487836"></affiliation>
            </author>
            <author role="aut">              <persName>                <forename type="first">France</forename>
                <surname>Mentré</surname>
              </persName>
              <idno type="halauthorid">181170</idno>
              <affiliation ref="#struct-1005021"></affiliation>
            </author>
            <author role="crp">              <persName>                <forename type="first">Nathan</forename>
                <surname>Peiffer-Smadja</surname>
              </persName>
              <email type="md5">5dd90ff3c5822b214ecf2d6cc3405015</email>
              <email type="domain">inserm.fr</email>
              <idno type="halauthorid">11800962</idno>
              <affiliation ref="#struct-1005021"></affiliation>
              <affiliation ref="#struct-487836"></affiliation>
            </author>
            <editor role="depositor">              <persName>                <forename>Myriam</forename>
                <surname>Bodescot</surname>
              </persName>
              <email type="md5">c1080fe2d5235c5abd827e8bd51dca64</email>
              <email type="domain">inserm.fr</email>
            </editor>
          </titleStmt>
          <editionStmt>            <edition n="v1" type="current">              <date type="whenSubmitted">2020-04-17 17:05:14</date>
              <date type="whenModified">2020-04-19 01:34:05</date>
              <date type="whenReleased">2020-04-17 17:35:28</date>
              <date type="whenProduced">2020-04-07</date>
              <ref type="externalLink" target="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7138382/pdf"></ref>
            </edition>
            <respStmt>              <resp>contributor</resp>
              <name key="702440">                <persName>                  <forename>Myriam</forename>
                  <surname>Bodescot</surname>
                </persName>
                <email type="md5">c1080fe2d5235c5abd827e8bd51dca64</email>
                <email type="domain">inserm.fr</email>
              </name>
            </respStmt>
          </editionStmt>
          <publicationStmt>            <distributor>CCSD</distributor>
            <idno type="halId">inserm-02546137</idno>
            <idno type="halUri">https://www.hal.inserm.fr/inserm-02546137</idno>
            <idno type="halBibtex">sallard:inserm-02546137</idno>
            <idno type="halRefHtml">Antiviral Research, Elsevier Masson, 2020, 178, pp.104791. ⟨10.1016/j.antiviral.2020.104791⟩</idno>
            <idno type="halRef">Antiviral Research, Elsevier Masson, 2020, 178, pp.104791. ⟨10.1016/j.antiviral.2020.104791⟩</idno>
          </publicationStmt>
          <seriesStmt>            <idno type="stamp" n="INSERM">INSERM - Institut national de la santé et de la recherche médicale</idno>
            <idno type="stamp" n="APHP" corresp="INSERM">AP-HP</idno>
            <idno type="stamp" n="PLEIADE" corresp="UNIV-PARIS13">Pléiade</idno>
            <idno type="stamp" n="LAGA" corresp="UNIV-PARIS13">Laboratoire d'Analyse, Géométrie et Applications</idno>
            <idno type="stamp" n="ENS-PARIS">Ecole Normale Supérieure de Paris</idno>
            <idno type="stamp" n="PSL">Paris Sciences et Lettres (PSL) Research University</idno>
            <idno type="stamp" n="SORBONNE-PARIS-NORD">Université Sorbonne Paris Nord</idno>
            <idno type="stamp" n="UNIV-PARIS13">Université Paris-Nord - Paris XIII </idno>
            <idno type="stamp" n="UNIVERSITE-PARIS" corresp="UNIV-PARIS">Université de Paris</idno>
            <idno type="stamp" n="UP-SANTE">Université de Paris - Faculté de Santé</idno>
            <idno type="stamp" n="USPC">Université Sorbonne Paris Cité</idno>
            <idno type="stamp" n="UNIV-PARIS">Université de Paris</idno>
          </seriesStmt>
          <notesStmt>            <note type="commentary">Elsevier Public Health emergency Collection</note>
            <note type="audience" n="2">International</note>
            <note type="popular" n="0">No</note>
            <note type="peer" n="1">Yes</note>
          </notesStmt>
          <sourceDesc>            <biblStruct>              <analytic>                <title xml:lang="en">Type 1 interferons as a potential treatment against COVID-19</title>
                <author role="aut">                  <persName>                    <forename type="first">Erwan</forename>
                    <surname>Sallard</surname>
                  </persName>
                  <idno type="halauthorid">11800961</idno>
                  <affiliation ref="#struct-59704"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">François-Xavier</forename>
                    <surname>Lescure</surname>
                  </persName>
                  <idno type="halauthorid">957302</idno>
                  <affiliation ref="#struct-1005021"></affiliation>
                  <affiliation ref="#struct-487836"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">Yazdan</forename>
                    <surname>Yazdanpanah</surname>
                  </persName>
                  <email type="md5">1171907f9f9de83a6d897c88c99cf2ac</email>
                  <email type="domain">bch.aphp.fr</email>
                  <idno type="halauthorid">848920</idno>
                  <affiliation ref="#struct-1005021"></affiliation>
                  <affiliation ref="#struct-487836"></affiliation>
                </author>
                <author role="aut">                  <persName>                    <forename type="first">France</forename>
                    <surname>Mentré</surname>
                  </persName>
                  <idno type="halauthorid">181170</idno>
                  <affiliation ref="#struct-1005021"></affiliation>
                </author>
                <author role="crp">                  <persName>                    <forename type="first">Nathan</forename>
                    <surname>Peiffer-Smadja</surname>
                  </persName>
                  <email type="md5">5dd90ff3c5822b214ecf2d6cc3405015</email>
                  <email type="domain">inserm.fr</email>
                  <idno type="halauthorid">11800962</idno>
                  <affiliation ref="#struct-1005021"></affiliation>
                  <affiliation ref="#struct-487836"></affiliation>
                </author>
              </analytic>
              <monogr>                <idno type="halJournalId" status="VALID">10572</idno>
                <idno type="issn">0166-3542</idno>
                <title level="j">Antiviral Research</title>
                <imprint>                  <publisher>Elsevier Masson</publisher>
                  <biblScope unit="volume">178</biblScope>
                  <biblScope unit="pp">104791</biblScope>
                  <date type="datePub">2020-04-07</date>
                </imprint>
              </monogr>
              <idno type="doi">10.1016/j.antiviral.2020.104791</idno>
              <idno type="pubmed">32275914</idno>
              <idno type="pubmedcentral">PMC7138382</idno>
            </biblStruct>
          </sourceDesc>
          <profileDesc>            <langUsage>              <language ident="en">English</language>
            </langUsage>
            <textClass>              <keywords scheme="author">                <term xml:lang="en">SARS-CoV-2</term>
                <term xml:lang="en">COVID-19</term>
                <term xml:lang="en">Interferon</term>
              </keywords>
              <classCode scheme="halDomain" n="sdv.mp.vir">Life Sciences [q-bio]/Microbiology and Parasitology/Virology</classCode>
              <classCode scheme="halDomain" n="sdv.mhep.me">Life Sciences [q-bio]/Human health and pathology/Emerging diseases</classCode>
              <classCode scheme="halTypology" n="ART">Journal articles</classCode>
            </textClass>
            <abstract xml:lang="en">              <p>Type 1 interferons have a broad antiviral activity in vitro and are currently evaluated in a clinical trial to treat MERS-CoV. In this review, we discuss preliminary data concerning the potential activity of type 1 interferons on SARS-CoV-2, and the relevance of evaluating these molecules in clinical trials for the treatment of COVID-19.</p>
            </abstract>
          </profileDesc>
        </hal>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Hal/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000178 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Hal/Corpus/biblio.hfd -nk 000178 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Sante
   |area=    SrasV1
   |flux=    Hal
   |étape=   Corpus
   |type=    RBID
   |clé=     Hal:inserm-02546137
   |texte=   Type 1 interferons as a potential treatment against COVID-19
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Apr 28 14:49:16 2020. Site generation: Sat Mar 27 22:06:49 2021

	Serveur d'exploration SRAS
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration SRAS

Type 1 interferons as a potential treatment against COVID-19

Type 1 interferons as a potential treatment against COVID-19

Source :

English descriptors

Abstract

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri