COVID-19 infection and rheumatoid arthritis: Faraway, so close!
Identifieur interne : 000921 ( 2020/Analysis ); précédent : 000920; suivant : 000922COVID-19 infection and rheumatoid arthritis: Faraway, so close!
Auteurs : Ennio Giulio Favalli [Italie] ; Francesca Ingegnoli [Italie] ; Orazio De Lucia [Italie] ; Gilberto Cincinelli [Italie] ; Rolando Cimaz [Italie] ; Roberto Caporali [Italie]Source :
- Autoimmunity Reviews [ 1568-9972 ] ; 2020.
Abstract
The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency. Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrome coronaviruses (SARS-CoV-2) is mainly supportive, even though several compounds are now under investigation for the treatment of this life-threatening disease. COVID-19 pandemic is certainly conditioning the treatment strategy of a complex disorder as rheumatoid arthritis (RA), whose infectious risk is increased compared to the general population because of an overall impairment of immune system typical of autoimmune diseases combined with the iatrogenic effect generated by corticosteroids and immunosuppressive drugs. However, the increasing knowledge about the pathophysiology of SARS-CoV-2 infection is leading to consider some anti-rheumatic drugs as potential treatment options for the management of COVID-19. In this review we will critically analyse the evidences on either positive or negative effect of drugs commonly used to treat RA in this particular scenario, in order to optimize the current approach to RA patients.
Url:
DOI: 10.1016/j.autrev.2020.102523
PubMed: 32205186
PubMed Central: 7102591
Affiliations:
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Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="af0010">Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milano, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milano</wicri:regionArea><wicri:noRegion>Milano</wicri:noRegion></affiliation></author></analytic><series><title level="j">Autoimmunity Reviews</title><idno type="ISSN">1568-9972</idno><idno type="eISSN">1873-0183</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The outbreak of the new coronavirus infections COVID-19 in December 2019 in China has quickly become a global health emergency. Given the lack of specific anti-viral therapies, the current management of severe acute respiratory syndrome coronaviruses (SARS-CoV-2) is mainly supportive, even though several compounds are now under investigation for the treatment of this life-threatening disease. COVID-19 pandemic is certainly conditioning the treatment strategy of a complex disorder as rheumatoid arthritis (RA), whose infectious risk is increased compared to the general population because of an overall impairment of immune system typical of autoimmune diseases combined with the iatrogenic effect generated by corticosteroids and immunosuppressive drugs. However, the increasing knowledge about the pathophysiology of SARS-CoV-2 infection is leading to consider some anti-rheumatic drugs as potential treatment options for the management of COVID-19. In this review we will critically analyse the evidences on either positive or negative effect of drugs commonly used to treat RA in this particular scenario, in order to optimize the current approach to RA patients.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Zhou, P" uniqKey="Zhou P">P. Zhou</name></author><author><name sortKey="Yang, X L" uniqKey="Yang X">X.-L. Yang</name></author><author><name sortKey="Wang, X G" uniqKey="Wang X">X.-G. Wang</name></author><author><name sortKey="Hu, B" uniqKey="Hu B">B. Hu</name></author><author><name sortKey="Zhang, L" uniqKey="Zhang L">L. Zhang</name></author><author><name sortKey="Zhang, W" uniqKey="Zhang W">W. Zhang</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tang, X" uniqKey="Tang X">X. Tang</name></author><author><name sortKey="Wu, C" uniqKey="Wu C">C. Wu</name></author><author><name sortKey="Li, X" uniqKey="Li X">X. 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Crotti</name></author><author><name sortKey="Biggioggero, M" uniqKey="Biggioggero M">M. Biggioggero</name></author><author><name sortKey="Caporali, R" uniqKey="Caporali R">R. Caporali</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Edwards, C J" uniqKey="Edwards C">C.J. Edwards</name></author><author><name sortKey="Galeazzi, M" uniqKey="Galeazzi M">M. Galeazzi</name></author><author><name sortKey="Bellinvia, S" uniqKey="Bellinvia S">S. Bellinvia</name></author><author><name sortKey="Ringer, A" uniqKey="Ringer A">A. Ringer</name></author><author><name sortKey="Dimitroulas, T" uniqKey="Dimitroulas T">T. Dimitroulas</name></author><author><name sortKey="Kitas, G" uniqKey="Kitas G">G. Kitas</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Italie</li></country><region><li>Lombardie</li></region><settlement><li>Milan</li></settlement></list><tree><country name="Italie"><region name="Lombardie"><name sortKey="Favalli, Ennio Giulio" sort="Favalli, Ennio Giulio" uniqKey="Favalli E" first="Ennio Giulio" last="Favalli">Ennio Giulio Favalli</name></region><name sortKey="Caporali, Roberto" sort="Caporali, Roberto" uniqKey="Caporali R" first="Roberto" last="Caporali">Roberto Caporali</name><name sortKey="Caporali, Roberto" sort="Caporali, Roberto" uniqKey="Caporali R" first="Roberto" last="Caporali">Roberto Caporali</name><name sortKey="Cimaz, Rolando" sort="Cimaz, Rolando" uniqKey="Cimaz R" first="Rolando" last="Cimaz">Rolando Cimaz</name><name sortKey="Cimaz, Rolando" sort="Cimaz, Rolando" uniqKey="Cimaz R" first="Rolando" last="Cimaz">Rolando Cimaz</name><name sortKey="Cincinelli, Gilberto" sort="Cincinelli, Gilberto" uniqKey="Cincinelli G" first="Gilberto" last="Cincinelli">Gilberto Cincinelli</name><name sortKey="De Lucia, Orazio" sort="De Lucia, Orazio" uniqKey="De Lucia O" first="Orazio" last="De Lucia">Orazio De Lucia</name><name sortKey="Ingegnoli, Francesca" sort="Ingegnoli, Francesca" uniqKey="Ingegnoli F" first="Francesca" last="Ingegnoli">Francesca Ingegnoli</name><name sortKey="Ingegnoli, Francesca" sort="Ingegnoli, Francesca" uniqKey="Ingegnoli F" first="Francesca" last="Ingegnoli">Francesca Ingegnoli</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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