Dramatic increase in HIV prevalence after scale-up of antiretroviral treatment.
Identifieur interne : 001347 ( PubMed/Curation ); précédent : 001346; suivant : 001348Dramatic increase in HIV prevalence after scale-up of antiretroviral treatment.
Auteurs : Jaffer Zaidi [États-Unis] ; Erofili Grapsa ; Frank Tanser ; Marie-Louise Newell ; Till B RnighausenSource :
- AIDS (London, England) [ 1473-5571 ] ; 2013.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Antirétroviraux (usage thérapeutique), Enfant, Femelle, Humains, Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Jeune adulte, Mâle, Population rurale, Prévalence, République d'Afrique du Sud (épidémiologie), Épidémiosurveillance, Études longitudinales.
- MESH :
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Antirétroviraux.
- épidémiologie : Infections à VIH, République d'Afrique du Sud.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Femelle, Humains, Jeune adulte, Mâle, Population rurale, Prévalence, Épidémiosurveillance, Études longitudinales.
- Wicri :
- geographic : Afrique du Sud.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Anti-Retroviral Agents.
- geographic , epidemiology : South Africa.
- drug therapy : HIV Infections.
- epidemiology : HIV Infections.
- Adolescent, Adult, Child, Epidemiological Monitoring, Female, Humans, Longitudinal Studies, Male, Middle Aged, Prevalence, Rural Population, Young Adult.
Abstract
To investigate HIV prevalence trends in a rural South African community after the scale-up of antiretroviral treatment (ART) in 2004.
DOI: 10.1097/QAD.0b013e328362e832
PubMed: 23669155
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adulte</term><term>Mâle</term><term>Population rurale</term><term>Prévalence</term><term>République d'Afrique du Sud (épidémiologie)</term><term>Épidémiosurveillance</term><term>Études longitudinales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-Retroviral Agents</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>South Africa</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antirétroviraux</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term><term>République d'Afrique du Sud</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Child</term><term>Epidemiological Monitoring</term><term>Female</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Rural Population</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Population rurale</term><term>Prévalence</term><term>Épidémiosurveillance</term><term>Études longitudinales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Afrique du Sud</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To investigate HIV prevalence trends in a rural South African community after the scale-up of antiretroviral treatment (ART) in 2004.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23669155</PMID><DateCreated><Year>2013</Year><Month>10</Month><Day>25</Day></DateCreated><DateCompleted><Year>2014</Year><Month>03</Month><Day>31</Day></DateCompleted><DateRevised><Year>2017</Year><Month>09</Month><Day>22</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1473-5571</ISSN><JournalIssue CitedMedium="Internet"><Volume>27</Volume><Issue>14</Issue><PubDate><Year>2013</Year><Month>Sep</Month><Day>10</Day></PubDate></JournalIssue><Title>AIDS (London, England)</Title><ISOAbbreviation>AIDS</ISOAbbreviation></Journal><ArticleTitle>Dramatic increase in HIV prevalence after scale-up of antiretroviral treatment.</ArticleTitle><Pagination><MedlinePgn>2301-5</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/QAD.0b013e328362e832</ELocationID><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To investigate HIV prevalence trends in a rural South African community after the scale-up of antiretroviral treatment (ART) in 2004.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We estimated adult HIV prevalence (ages 15-49 years) using data from a large, longitudinal, population-based HIV surveillance in rural KwaZulu-Natal, South Africa, over the period from 2004 (the year when the public-sector ART scale-up started) to 2011. We control for selection effects due to surveillance nonparticipation using multiple imputation. We further linked the surveillance data to patient records from the local HIV treatment program to estimate ART coverage.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">ART coverage of all HIV-infected people in this community increased from 0% in 2004 to 31% in 2011. Over the same observation period adult HIV prevalence increased steadily from 21 to 29%. The change in overall HIV prevalence is nearly completely explained by an increase of HIV-infected people receiving ART, and it is largely driven by increases in HIV prevalence in women and men older than 24 years.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The observed dramatic increase in adult HIV prevalence can most likely be explained by increased survival of HIV-infected people due to ART. Future studies should decompose HIV prevalence trends into HIV incidence and HIV-specific mortality changes to further improve the causal attribution of prevalence increases to treatment success rather than prevention failure.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Zaidi</LastName><ForeName>Jaffer</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>aAfrica Centre for Health and Population Studies, University of KwaZulu-Natal, Mtubatuba, KwaZulu-Natal, South Africa bUniversity College London Institute of Child Health, London, UK cDepartment of Global Health and Population, Harvard School of Public Health, Boston, Massachusetts, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grapsa</LastName><ForeName>Erofili</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Tanser</LastName><ForeName>Frank</ForeName><Initials>F</Initials></Author><Author ValidYN="Y"><LastName>Newell</LastName><ForeName>Marie-Louise</ForeName><Initials>ML</Initials></Author><Author ValidYN="Y"><LastName>Bärnighausen</LastName><ForeName>Till</ForeName><Initials>T</Initials></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>097410</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant><Grant><GrantID>R01 HD058482</GrantID><Acronym>HD</Acronym><Agency>NICHD NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>082384/Z/07/Z</GrantID><Agency>Wellcome Trust</Agency><Country>United Kingdom</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>AIDS</MedlineTA><NlmUniqueID>8710219</NlmUniqueID><ISSNLinking>0269-9370</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D044966">Anti-Retroviral Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CitationSubset>X</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Int J Epidemiol. 2008 Oct;37(5):956-62</RefSource><PMID Version="1">17998242</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AIDS. 2007 Nov;21 Suppl 7:S29-38</RefSource><PMID Version="1">18040162</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AIDS. 2009 Jul 17;23(11):1397-404</RefSource><PMID Version="1">19381076</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 2009 Sep 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Population</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013019" MajorTopicYN="N" Type="Geographic">South Africa</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">NIHMS642391</OtherID><OtherID Source="NLM">PMC4264533</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>5</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>5</Month><Day>15</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>4</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23669155</ArticleId><ArticleId 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