Ocular manifestation of HIV/AIDS and correlation with CD4+ cells count among adult HIV/AIDS patients in Jimma town, Ethiopia: a cross sectional study.
Identifieur interne : 001213 ( PubMed/Curation ); précédent : 001212; suivant : 001214Ocular manifestation of HIV/AIDS and correlation with CD4+ cells count among adult HIV/AIDS patients in Jimma town, Ethiopia: a cross sectional study.
Auteurs : Sisay Bekele [Éthiopie] ; Yeshigeta Gelaw ; Fasil TessemaSource :
- BMC ophthalmology [ 1471-2415 ] ; 2013.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse de régression, Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Humains, Infections à VIH (), Infections à VIH (immunologie), Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Jeune adulte, Maladies de l'oeil (épidémiologie), Maladies de l'oeil (étiologie), Mâle, Numération des lymphocytes CD4, Prévalence, Thérapie antirétrovirale hautement active, Éthiopie (épidémiologie), Études transversales.
- MESH :
- immunologie : Infections à VIH.
- traitement médicamenteux : Infections à VIH.
- épidémiologie : Infections à VIH, Maladies de l'oeil, Éthiopie.
- étiologie : Maladies de l'oeil.
- Adulte, Adulte d'âge moyen, Analyse de régression, Facteurs de l'âge, Facteurs de risque, Facteurs sexuels, Femelle, Humains, Infections à VIH, Jeune adulte, Mâle, Numération des lymphocytes CD4, Prévalence, Thérapie antirétrovirale hautement active, Études transversales.
- Wicri :
- geographic : Éthiopie.
English descriptors
- KwdEn :
- Adult, Age Factors, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Cross-Sectional Studies, Ethiopia (epidemiology), Eye Diseases (epidemiology), Eye Diseases (etiology), Female, HIV Infections (complications), HIV Infections (drug therapy), HIV Infections (epidemiology), HIV Infections (immunology), Humans, Male, Middle Aged, Prevalence, Regression Analysis, Risk Factors, Sex Factors, Young Adult.
- MESH :
- geographic , epidemiology : Ethiopia.
- complications : HIV Infections.
- drug therapy : HIV Infections.
- epidemiology : Eye Diseases, HIV Infections.
- etiology : Eye Diseases.
- immunology : HIV Infections.
- Adult, Age Factors, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Prevalence, Regression Analysis, Risk Factors, Sex Factors, Young Adult.
Abstract
HIV/AIDS is one of twenty first century's challenges to human being with protean manifestation affecting nearly all organs of our body. It is causing high morbidity and mortality especially in sub-Saharan Africa with numerous ocular complications and blindness. The purpose of this study was to determine the patterns of ocular manifestations of HIV/AIDS and their correlation with CD4+T cells count.
DOI: 10.1186/1471-2415-13-20
PubMed: 23710936
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adulte</term><term>Maladies de l'oeil (épidémiologie)</term><term>Maladies de l'oeil (étiologie)</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prévalence</term><term>Thérapie antirétrovirale hautement active</term><term>Éthiopie (épidémiologie)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ethiopia</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Eye Diseases</term><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Eye Diseases</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term><term>Maladies de l'oeil</term><term>Éthiopie</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Maladies de l'oeil</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Age Factors</term><term>Antiretroviral Therapy, Highly Active</term><term>CD4 Lymphocyte Count</term><term>Cross-Sectional Studies</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prevalence</term><term>Regression Analysis</term><term>Risk Factors</term><term>Sex Factors</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse de régression</term><term>Facteurs de l'âge</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Humains</term><term>Infections à VIH</term><term>Jeune adulte</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prévalence</term><term>Thérapie antirétrovirale hautement active</term><term>Études transversales</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Éthiopie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">HIV/AIDS is one of twenty first century's challenges to human being with protean manifestation affecting nearly all organs of our body. It is causing high morbidity and mortality especially in sub-Saharan Africa with numerous ocular complications and blindness. The purpose of this study was to determine the patterns of ocular manifestations of HIV/AIDS and their correlation with CD4+T cells count.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">23710936</PMID><DateCreated><Year>2013</Year><Month>06</Month><Day>13</Day></DateCreated><DateCompleted><Year>2013</Year><Month>12</Month><Day>31</Day></DateCompleted><DateRevised><Year>2015</Year><Month>04</Month><Day>26</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1471-2415</ISSN><JournalIssue CitedMedium="Internet"><Volume>13</Volume><PubDate><Year>2013</Year><Month>May</Month><Day>27</Day></PubDate></JournalIssue><Title>BMC ophthalmology</Title><ISOAbbreviation>BMC Ophthalmol</ISOAbbreviation></Journal><ArticleTitle>Ocular manifestation of HIV/AIDS and correlation with CD4+ cells count among adult HIV/AIDS patients in Jimma town, Ethiopia: a cross sectional study.</ArticleTitle><Pagination><MedlinePgn>20</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/1471-2415-13-20</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">HIV/AIDS is one of twenty first century's challenges to human being with protean manifestation affecting nearly all organs of our body. It is causing high morbidity and mortality especially in sub-Saharan Africa with numerous ocular complications and blindness. The purpose of this study was to determine the patterns of ocular manifestations of HIV/AIDS and their correlation with CD4+T cells count.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">A cross-sectional study was done on 348 HIV-positive patients presented to Anti-Retroviral Therapy clinics. Data were collected using face-to-face interview, clinical examination and laboratory investigation, and analyzed using SPSS version 13 software. Statistical association test was done and p<0.05 was considered significant. Other statistical tests like student t-test and logistic regression were also done.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Of 348 patients, 175 were on antiretroviral therapy and 173 were not on therapy. The mean duration of therapy was 27 months. The overall prevalence of ocular manifestations was 25.3%. The commonest ocular manifestation was keratoconjunctivitis sicca (11.3%) followed by blepharitis (3.2%), molluscum contagiosum (2.6%), conjunctival squamous cell carcinoma (2.3%), conjunctival microvasculopathy (2.3%), cranial nerve palsies (2%), herpes zoster ophthalmicus (HZO) (1.2%), and HIV retinopathy (0.6%). HIV retinopathy and conjunctival microvasculopathy were common in patient with CD4+ count of <200 cells/μl while HZO and molluscum contagiosum were common in patients with CD4+ count of 200-499 cells/μl. Prevalence of ocular manifestation was higher among patients on HAART (32.6%) than those patients not on HAART (17.9%) (p<0.05). There was statistically significant association between ocular manifestation and sex, CD4+Tcells count, and age (p<0.05). CD4+ count, <200 cells/μl and age >35 years were independent risk factors for ocular manifestations.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The study showed that the prevalence of ocular manifestation of HIV/AIDS is lower than previous studies and could be due to antiretroviral therapy. Lower CD4 count is a risk as well as predictor for ocular manifestations.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bekele</LastName><ForeName>Sisay</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Ophthalmology, College of Public Health and Medical Sciences, Jimma University, Jimma, Ethiopia. sisayop@gmail.com</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gelaw</LastName><ForeName>Yeshigeta</ForeName><Initials>Y</Initials></Author><Author ValidYN="Y"><LastName>Tessema</LastName><ForeName>Fasil</ForeName><Initials>F</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2013</Year><Month>05</Month><Day>27</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>BMC Ophthalmol</MedlineTA><NlmUniqueID>100967802</NlmUniqueID><ISSNLinking>1471-2415</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Br J Ophthalmol. 1994 Oct;78(10):757-9</RefSource><PMID Version="1">7803351</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ophthalmology. 1994 Sep;101(9):1488-502</RefSource><PMID Version="1">8090452</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1997 May 17;349(9063):1443-5</RefSource><PMID Version="1">9164318</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>AIDS. 1999 Feb 4;13(2):203-12</RefSource><PMID Version="1">10202826</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Ophthalmol. 1999 Mar;83(3):339-42</RefSource><PMID Version="1">10365044</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Trop Med Int Health. 1999 Jul;4(7):487-92</RefSource><PMID Version="1">10470340</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Retina. 2005 Jul-Aug;25(5):633-49; quiz 682-3</RefSource><PMID Version="1">16077362</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Indian J Ophthalmol. 2008 Sep-Oct;56(5):391-3</RefSource><PMID Version="1">18711267</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Ophthalmol. 2009 Jan;93(1):88-90</RefSource><PMID Version="1">18952644</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Int J Infect Dis. 2009 Mar;13(2):243-6</RefSource><PMID Version="1">18945632</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ocul Immunol Inflamm. 1999 Dec;7(3-4):173-7</RefSource><PMID Version="1">10611725</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Optometry. 2004 Oct;75(10):624-8</RefSource><PMID Version="1">15508863</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ophthalmology. 1990 Aug;97(8):1008-10</RefSource><PMID Version="1">2402409</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Intern Med. 1994 Jul 25;154(14):1561-73</RefSource><PMID Version="1">7913314</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Dakar Med. 1993;38(1):97-100</RefSource><PMID Version="1">7882859</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000367" MajorTopicYN="N">Age Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D023241" MajorTopicYN="N">Antiretroviral Therapy, Highly Active</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018791" MajorTopicYN="Y">CD4 Lymphocyte Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005002" MajorTopicYN="N" Type="Geographic">Ethiopia</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005128" MajorTopicYN="N">Eye Diseases</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName><QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015995" MajorTopicYN="N">Prevalence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012044" MajorTopicYN="N">Regression Analysis</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012737" MajorTopicYN="N">Sex Factors</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC3679865</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2013</Year><Month>01</Month><Day>23</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2013</Year><Month>05</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2013</Year><Month>5</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2013</Year><Month>5</Month><Day>29</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2014</Year><Month>1</Month><Day>1</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>epublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">23710936</ArticleId><ArticleId IdType="pii">1471-2415-13-20</ArticleId><ArticleId IdType="doi">10.1186/1471-2415-13-20</ArticleId><ArticleId IdType="pmc">PMC3679865</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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