Le SIDA en Afrique subsaharienne (serveur d'exploration)

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Where do HIV-infected adolescents go after transfer? - Tracking transition/transfer of HIV-infected adolescents using linkage of cohort data to a health information system platform.

Identifieur interne : 000788 ( PubMed/Curation ); précédent : 000787; suivant : 000789

Where do HIV-infected adolescents go after transfer? - Tracking transition/transfer of HIV-infected adolescents using linkage of cohort data to a health information system platform.

Auteurs : Mary-Ann Davies [Afrique du Sud] ; Priscilla Tsondai [Afrique du Sud] ; Nicki Tiffin [Afrique du Sud] ; Brian Eley [Afrique du Sud] ; Helena Rabie [Afrique du Sud] ; Jonathan Euvrard [Afrique du Sud] ; Catherine Orrell [Afrique du Sud] ; Hans Prozesky [Afrique du Sud] ; Robin Wood [Afrique du Sud] ; Dolphina Cogill [Afrique du Sud] ; Andreas D. Haas [Suisse] ; Annette H. Sohn [Thaïlande] ; Andrew Boulle [Afrique du Sud]

Source :

RBID : pubmed:28530037

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English descriptors

Abstract

To evaluate long-term outcomes in HIV-infected adolescents, it is important to identify ways of tracking outcomes after transfer to a different health facility. The Department of Health (DoH) in the Western Cape Province (WCP) of South Africa uses a single unique identifier for all patients across the health service platform. We examined adolescent outcomes after transfer by linking data from four International epidemiology Databases to Evaluate AIDS Southern Africa (IeDEA-SA) cohorts in the WCP with DoH data.

DOI: 10.7448/IAS.20.4.21668
PubMed: 28530037

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pubmed:28530037

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<div type="abstract" xml:lang="en">To evaluate long-term outcomes in HIV-infected adolescents, it is important to identify ways of tracking outcomes after transfer to a different health facility. The Department of Health (DoH) in the Western Cape Province (WCP) of South Africa uses a single unique identifier for all patients across the health service platform. We examined adolescent outcomes after transfer by linking data from four International epidemiology Databases to Evaluate AIDS Southern Africa (IeDEA-SA) cohorts in the WCP with DoH data.</div>
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<Year>2017</Year>
<Month>05</Month>
<Day>22</Day>
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<DateCompleted>
<Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
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<Year>2017</Year>
<Month>10</Month>
<Day>11</Day>
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<ISSN IssnType="Electronic">1758-2652</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>20</Volume>
<Issue>Suppl 3</Issue>
<PubDate>
<Year>2017</Year>
<Month>05</Month>
<Day>16</Day>
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<Title>Journal of the International AIDS Society</Title>
<ISOAbbreviation>J Int AIDS Soc</ISOAbbreviation>
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<ArticleTitle>Where do HIV-infected adolescents go after transfer? - Tracking transition/transfer of HIV-infected adolescents using linkage of cohort data to a health information system platform.</ArticleTitle>
<Pagination>
<MedlinePgn>21668</MedlinePgn>
</Pagination>
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<Abstract>
<AbstractText Label="INTRODUCTION">To evaluate long-term outcomes in HIV-infected adolescents, it is important to identify ways of tracking outcomes after transfer to a different health facility. The Department of Health (DoH) in the Western Cape Province (WCP) of South Africa uses a single unique identifier for all patients across the health service platform. We examined adolescent outcomes after transfer by linking data from four International epidemiology Databases to Evaluate AIDS Southern Africa (IeDEA-SA) cohorts in the WCP with DoH data.</AbstractText>
<AbstractText Label="METHODS">We included adolescents on antiretroviral therapy who transferred out of their original cohort from 10 to 19 years of age between 2004 and 2014. The DoH conducted the linkage separately for each cohort and linked anonymized data were then combined. The primary outcome was successful transfer defined as having a patient record at a facility other than the original facility after the transfer date. Secondary outcomes included the proportion of patients retained, with HIV-RNA <400 copies/ml and CD4 > 500 cells/µl at 1, 2 and 3 years post-transfer.</AbstractText>
<AbstractText Label="RESULTS">Of 460 adolescents transferred out (53% female), 72% transferred at 10-14 years old, and 79% transferred out of tertiary facilities. Overall, 81% of patients transferred successfully at a median (interquartile range) of 56 (27-134) days following transfer date; 95% reached the transfer site <18 months after transfer out. Among those transferring successfully, the proportion retained decreased from 1 to 3 years post-transfer (90-84%). There was no significant difference between transfer and 1-3 years post-transfer in the proportion of retained adolescents with HIV-RNA <400 copies/ml and CD4 > 500 cells/µl except for HIV-RNA <400 copies/ml at 3 years (86% vs. 75%; p = 0.007). The proportion virologically suppressed and with CD4 > 500 cells/µl was significantly lower at 1 and 2 years post-transfer in those transferring at 15-19 vs. 10-14 years of age. Using laboratory data alone over-estimated time to successful transfer.</AbstractText>
<AbstractText Label="CONCLUSIONS">Linking cohort data to health information system data allowed efficient assessment of post-transfer outcomes. Although >80% of adolescents transferred successfully with nearly 85% of them retained for 3 years post-transfer, the decline in the proportion virologically suppressed and poorer outcomes in older adolescents are concerns.​.</AbstractText>
</Abstract>
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<ForeName>Mary-Ann</ForeName>
<Initials>MA</Initials>
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<Affiliation>Centre for Infectious Disease Epidemiology and Research (CIDER), School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.</Affiliation>
</AffiliationInfo>
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<LastName>Tsondai</LastName>
<ForeName>Priscilla</ForeName>
<Initials>P</Initials>
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<Affiliation>Centre for Infectious Disease Epidemiology and Research (CIDER), School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.</Affiliation>
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<Affiliation>Centre for Infectious Disease Epidemiology and Research (CIDER), School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.</Affiliation>
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<AffiliationInfo>
<Affiliation>Western Cape Province Department of Health, Health Impact Assessment Directorate, Cape Town, South Africa.</Affiliation>
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<RefSource>S Afr Med J. 2009 Oct;99(10):730-7</RefSource>
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<RefSource>JAMA. 2007 Oct 24;298(16):1888-99</RefSource>
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<Keyword MajorTopicYN="Y">HIV-1</Keyword>
<Keyword MajorTopicYN="Y">adolescents</Keyword>
<Keyword MajorTopicYN="Y">antiretroviral</Keyword>
<Keyword MajorTopicYN="Y">data linkage</Keyword>
<Keyword MajorTopicYN="Y">sub-Saharan Africa</Keyword>
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