Associations between HIV, highly active anti-retroviral therapy, and hypertensive disorders of pregnancy among maternal deaths in South Africa 2011-2013.
Identifieur interne : 000743 ( PubMed/Curation ); précédent : 000742; suivant : 000744Associations between HIV, highly active anti-retroviral therapy, and hypertensive disorders of pregnancy among maternal deaths in South Africa 2011-2013.
Auteurs : Hannah M. Sebitloane [Afrique du Sud] ; Jagidesa Moodley [Afrique du Sud] ; Benn Sartorius [Afrique du Sud]Source :
- International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [ 1879-3479 ] ; 2017.
Descripteurs français
- KwdFr :
- MESH :
- mortalité : Prééclampsie.
- traitement médicamenteux : Infections à VIH.
- épidémiologie : Infections à VIH, République d'Afrique du Sud.
- Adulte, Facteurs de risque, Femelle, Grossesse, Humains, Mortalité maternelle, Thérapie antirétrovirale hautement active, Études rétrospectives.
English descriptors
- KwdEn :
- MESH :
- drug therapy : HIV Infections.
- epidemiology : HIV Infections, South Africa.
- mortality : Pre-Eclampsia.
- Adult, Antiretroviral Therapy, Highly Active, Female, Humans, Maternal Mortality, Pregnancy, Retrospective Studies, Risk Factors.
Abstract
To explore potential relationships between HIV and highly active anti-retroviral therapy (HAART), and hypertensive disorders of pregnancy (HDP).
DOI: 10.1002/ijgo.12038
PubMed: 28099739
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pubmed:28099739Le document en format XML
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<term>Female</term>
<term>HIV Infections (drug therapy)</term>
<term>HIV Infections (epidemiology)</term>
<term>Humans</term>
<term>Maternal Mortality</term>
<term>Pre-Eclampsia (mortality)</term>
<term>Pregnancy</term>
<term>Retrospective Studies</term>
<term>Risk Factors</term>
<term>South Africa (epidemiology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Grossesse</term>
<term>Humains</term>
<term>Infections à VIH (traitement médicamenteux)</term>
<term>Infections à VIH (épidémiologie)</term>
<term>Mortalité maternelle</term>
<term>Prééclampsie (mortalité)</term>
<term>République d'Afrique du Sud (épidémiologie)</term>
<term>Thérapie antirétrovirale hautement active</term>
<term>Études rétrospectives</term>
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<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term>
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<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term>
<term>South Africa</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Pre-Eclampsia</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Prééclampsie</term>
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<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term>
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<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term>
<term>République d'Afrique du Sud</term>
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<term>Antiretroviral Therapy, Highly Active</term>
<term>Female</term>
<term>Humans</term>
<term>Maternal Mortality</term>
<term>Pregnancy</term>
<term>Retrospective Studies</term>
<term>Risk Factors</term>
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<term>Facteurs de risque</term>
<term>Femelle</term>
<term>Grossesse</term>
<term>Humains</term>
<term>Mortalité maternelle</term>
<term>Thérapie antirétrovirale hautement active</term>
<term>Études rétrospectives</term>
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<front><div type="abstract" xml:lang="en">To explore potential relationships between HIV and highly active anti-retroviral therapy (HAART), and hypertensive disorders of pregnancy (HDP).</div>
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<Title>International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics</Title>
<ISOAbbreviation>Int J Gynaecol Obstet</ISOAbbreviation>
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<ArticleTitle>Associations between HIV, highly active anti-retroviral therapy, and hypertensive disorders of pregnancy among maternal deaths in South Africa 2011-2013.</ArticleTitle>
<Pagination><MedlinePgn>195-199</MedlinePgn>
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<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To explore potential relationships between HIV and highly active anti-retroviral therapy (HAART), and hypertensive disorders of pregnancy (HDP).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">A retrospective secondary analysis of maternal-deaths data from the 2011-2013 Saving Mothers Report from South Africa. The incidence of HIV infection amongst individuals who died owing to HDP was determined and comparisons were made based on HIV status and the use of HAART.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Among 4452 maternal deaths recorded in the Saving Mothers report, a lower risk of a maternal deaths being due to HDP was observed among women who had HIV infections compared with women who did not have HIV (relative risk [RR] 0.57, 95% confidence interval [CI] 0.51-0.64). Further, reduced odds of death being due to HDP were recorded among women with AIDS not undergoing HAART compared with women with HIV who did not require treatment (RR 0.42, 95% CI 0.3-0.58). Notably, among all women with AIDS, a greater risk of death due to HDP was demonstrated among those who received HAART compared with those who did not (RR 1.15, 95% CI 1.02-1.29).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">HIV and AIDS were associated with a decreased risk of HDP being the primary cause of death; the use of HAART increased this risk.</AbstractText>
<CopyrightInformation>© 2016 International Federation of Gynecology and Obstetrics.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Sebitloane</LastName>
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<AffiliationInfo><Affiliation>Discipline of Obstetrics and Gynaecology, Nelson Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.</Affiliation>
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<AffiliationInfo><Affiliation>Women's Health and HIV Research Unit, Discipline of Obstetrics and Gynaecology, Nelson Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.</Affiliation>
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<ForeName>Benn</ForeName>
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<AffiliationInfo><Affiliation>Discipline of Public Health, School of Nursing and Public Health, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.</Affiliation>
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<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">HIV infection</Keyword>
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<Keyword MajorTopicYN="Y">Hypertensive diseases of pregnancy</Keyword>
<Keyword MajorTopicYN="Y">Pre-eclampsia</Keyword>
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