Kaposi's sarcoma in sub-Saharan Africa: a current perspective.
Identifieur interne : 000188 ( PubMed/Curation ); précédent : 000187; suivant : 000189Kaposi's sarcoma in sub-Saharan Africa: a current perspective.
Auteurs : A. Mosam [Afrique du Sud] ; J. Aboobaker ; F. ShaikSource :
- Current opinion in infectious diseases [ 1473-6527 ] ; 2010.
Descripteurs français
- KwdFr :
- Afrique subsaharienne (épidémiologie), Antirétroviraux (usage thérapeutique), Humains, Incidence, Infections opportunistes liées au SIDA (anatomopathologie), Infections opportunistes liées au SIDA (traitement médicamenteux), Infections opportunistes liées au SIDA (transmission), Infections opportunistes liées au SIDA (épidémiologie), Sarcome de Kaposi (anatomopathologie), Sarcome de Kaposi (traitement médicamenteux), Sarcome de Kaposi (épidémiologie), Syndrome inflammatoire de restauration immunitaire (), Études séroépidémiologiques.
- MESH :
- anatomopathologie : Infections opportunistes liées au SIDA, Sarcome de Kaposi.
- traitement médicamenteux : Infections opportunistes liées au SIDA, Sarcome de Kaposi.
- usage thérapeutique : Antirétroviraux, Infections opportunistes liées au SIDA.
- épidémiologie : Afrique subsaharienne, Infections opportunistes liées au SIDA, Sarcome de Kaposi.
- Humains, Incidence, Syndrome inflammatoire de restauration immunitaire, Études séroépidémiologiques.
English descriptors
- KwdEn :
- AIDS-Related Opportunistic Infections (drug therapy), AIDS-Related Opportunistic Infections (epidemiology), AIDS-Related Opportunistic Infections (pathology), AIDS-Related Opportunistic Infections (transmission), Africa South of the Sahara (epidemiology), Anti-Retroviral Agents (therapeutic use), Humans, Immune Reconstitution Inflammatory Syndrome (chemically induced), Incidence, Sarcoma, Kaposi (drug therapy), Sarcoma, Kaposi (epidemiology), Sarcoma, Kaposi (pathology), Seroepidemiologic Studies.
- MESH :
- chemical , therapeutic use : Anti-Retroviral Agents.
- geographic , epidemiology : Africa South of the Sahara.
- chemically induced : Immune Reconstitution Inflammatory Syndrome.
- drug therapy : AIDS-Related Opportunistic Infections, Sarcoma, Kaposi.
- epidemiology : AIDS-Related Opportunistic Infections, Sarcoma, Kaposi.
- pathology : AIDS-Related Opportunistic Infections, Sarcoma, Kaposi.
- transmission : AIDS-Related Opportunistic Infections.
- Humans, Incidence, Seroepidemiologic Studies.
Abstract
The aim of this review is to summarize the most recent published literature on HIV/AIDS Kaposi's sarcoma in sub-Saharan Africa (SSA). We attempted to update readers on the epidemiology of Kaposi's sarcoma herpesvirus infection and HIV Kaposi's sarcoma in SSA, as well as clinical features, therapy and immune reconstitution inflammatory syndrome associated with HIV Kaposi's sarcoma.
DOI: 10.1097/QCO.0b013e328335b01a
PubMed: 19996745
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We attempted to update readers on the epidemiology of Kaposi's sarcoma herpesvirus infection and HIV Kaposi's sarcoma in SSA, as well as clinical features, therapy and immune reconstitution inflammatory syndrome associated with HIV Kaposi's sarcoma.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19996745</PMID><DateCreated><Year>2010</Year><Month>03</Month><Day>02</Day></DateCreated><DateCompleted><Year>2010</Year><Month>05</Month><Day>11</Day></DateCompleted><DateRevised><Year>2012</Year><Month>01</Month><Day>31</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1473-6527</ISSN><JournalIssue CitedMedium="Internet"><Volume>23</Volume><Issue>2</Issue><PubDate><Year>2010</Year><Month>Apr</Month></PubDate></JournalIssue><Title>Current opinion in infectious diseases</Title><ISOAbbreviation>Curr. Opin. Infect. Dis.</ISOAbbreviation></Journal><ArticleTitle>Kaposi's sarcoma in sub-Saharan Africa: a current perspective.</ArticleTitle><Pagination><MedlinePgn>119-23</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1097/QCO.0b013e328335b01a</ELocationID><Abstract><AbstractText Label="PURPOSE OF REVIEW" NlmCategory="OBJECTIVE">The aim of this review is to summarize the most recent published literature on HIV/AIDS Kaposi's sarcoma in sub-Saharan Africa (SSA). We attempted to update readers on the epidemiology of Kaposi's sarcoma herpesvirus infection and HIV Kaposi's sarcoma in SSA, as well as clinical features, therapy and immune reconstitution inflammatory syndrome associated with HIV Kaposi's sarcoma.</AbstractText><AbstractText Label="RECENT FINDINGS" NlmCategory="RESULTS">Seroprevalence rates of Kaposi's sarcoma herpesvirus differ across SSA; it is low in South African children as compared to endemic areas like Uganda. The major route of transmission in SSA is horizontal rather than sexual. The incidence of Kaposi's sarcoma has increased exponentially with the HIV/AIDS pandemic with a shift in trend demonstrating a dramatic increase in females and occurrence in younger individuals. Kaposi's sarcoma specific therapy is underutilized due to poor access to highly active antiretroviral therapy and financial constraints in SSA. As highly active antiretroviral therapy becomes available, clinicians treating HIV/AIDS in SSA need to have a high index of suspicion of Kaposi's sarcoma immune reconstitution inflammatory syndrome events.</AbstractText><AbstractText Label="SUMMARY" NlmCategory="CONCLUSIONS">Kaposi's sarcoma is a public health concern in SSA. More studies appropriate to therapy for Kaposi's sarcoma in resource-poor environments like SSA are imperative. We are hopeful that with the increased availability of highly active antiretroviral therapy, the incidence of HIV Kaposi's sarcoma will decrease and management will improve, as it has in the West.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Mosam</LastName><ForeName>A</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Department of Dermatology, Nelson R. 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