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Immunity against HIV/AIDS, malaria, and tuberculosis during co-infections with neglected infectious diseases: recommendations for the European Union research priorities.

Identifieur interne : 001873 ( PubMed/Corpus ); précédent : 001872; suivant : 001874

Immunity against HIV/AIDS, malaria, and tuberculosis during co-infections with neglected infectious diseases: recommendations for the European Union research priorities.

Auteurs : Diana Boraschi ; Markos Abebe Alemayehu ; Abraham Aseffa ; Francesca Chiodi ; John Chisi ; Gianfranco Del Prete ; T Mark Doherty ; Ibrahim Elhassan ; Howard Engers ; Ben Gyan ; Ali M. Harandi ; Thomas Kariuki ; Fred Kironde ; Bourema Kouriba ; Jean Langhorne ; Tamás Laskay ; Donata Medaglini ; Ole Olesen ; Philip Onyebujoh ; Carla Palma ; Robert Sauerwein ; Elopy Sibanda ; Ulrich Steinhoff ; Aldo Tagliabue ; Andreas Thiel ; Mahnaz Vahedi ; Marita Troye-Blomberg

Source :

RBID : pubmed:18575596

English descriptors

Abstract

Infectious diseases remain a major health and socioeconomic problem in many low-income countries, particularly in sub-Saharan Africa. For many years, the three most devastating diseases, HIV/AIDS, malaria, and tuberculosis (TB) have received most of the world's attention. However, in rural and impoverished urban areas, a number of infectious diseases remain neglected and cause massive suffering. It has been calculated that a group of 13 neglected infectious diseases affects over one billion people, corresponding to a sixth of the world's population. These diseases include infections with different types of worms and parasites, cholera, and sleeping sickness, and can cause significant mortality and severe disabilities in low-income countries. For most of these diseases, vaccines are either not available, poorly effective, or too expensive. Moreover, these neglected diseases often occur in individuals who are also affected by HIV/AIDS, malaria, or TB, making the problem even more serious and indicating that co-infections are the rule rather than the exception in many geographical areas. To address the importance of combating co-infections, scientists from 14 different countries in Africa and Europe met in Addis Ababa, Ethiopia, on September 9-11, 2007. The message coming from these scientists is that the only possibility for winning the fight against infections in low-income countries is by studying, in the most global way possible, the complex interaction between different infections and conditions of malnourishment. The new scientific and technical tools of the post-genomic era can allow us to reach this goal. However, a concomitant effort in improving education and social conditions will be needed to make the scientific findings effective.

DOI: 10.1371/journal.pntd.0000255
PubMed: 18575596

Links to Exploration step

pubmed:18575596

Le document en format XML

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<RefSource>Immunobiology. 2007;212(6):475-90</RefSource>
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<RefSource>PLoS Med. 2007 May;4(5):e181</RefSource>
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<RefSource>Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16645-50</RefSource>
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