High risk of loss to follow-up among South African children on ART during transfer, a retrospective cohort analysis with community tracing.
Identifieur interne : 000E90 ( PubMed/Corpus ); précédent : 000E89; suivant : 000E91High risk of loss to follow-up among South African children on ART during transfer, a retrospective cohort analysis with community tracing.
Auteurs : Chloe A. Teasdale ; Nonzwakazi Sogaula ; Katharine A. Yuengling ; Zachary J. Peters ; Anthony Mutiti ; Lungile Pepeta ; Elaine J. AbramsSource :
- Journal of the International AIDS Society [ 1758-2652 ] ; 2017.
Abstract
Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa.
DOI: 10.7448/IAS.20.1.21748
PubMed: 28691440
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">High risk of loss to follow-up among South African children on ART during transfer, a retrospective cohort analysis with community tracing.</title><author><name sortKey="Teasdale, Chloe A" sort="Teasdale, Chloe A" uniqKey="Teasdale C" first="Chloe A" last="Teasdale">Chloe A. Teasdale</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sogaula, Nonzwakazi" sort="Sogaula, Nonzwakazi" uniqKey="Sogaula N" first="Nonzwakazi" last="Sogaula">Nonzwakazi Sogaula</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Yuengling, Katharine A" sort="Yuengling, Katharine A" uniqKey="Yuengling K" first="Katharine A" last="Yuengling">Katharine A. Yuengling</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Peters, Zachary J" sort="Peters, Zachary J" uniqKey="Peters Z" first="Zachary J" last="Peters">Zachary J. Peters</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mutiti, Anthony" sort="Mutiti, Anthony" uniqKey="Mutiti A" first="Anthony" last="Mutiti">Anthony Mutiti</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pepeta, Lungile" sort="Pepeta, Lungile" uniqKey="Pepeta L" first="Lungile" last="Pepeta">Lungile Pepeta</name><affiliation><nlm:affiliation>Port Elizabeth Hospital Complex, Department of Paediatrics, Port Elizabeth, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Abrams, Elaine J" sort="Abrams, Elaine J" uniqKey="Abrams E" first="Elaine J" last="Abrams">Elaine J. Abrams</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28691440</idno><idno type="pmid">28691440</idno><idno type="doi">10.7448/IAS.20.1.21748</idno><idno type="wicri:Area/PubMed/Corpus">000E90</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000E90</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">High risk of loss to follow-up among South African children on ART during transfer, a retrospective cohort analysis with community tracing.</title><author><name sortKey="Teasdale, Chloe A" sort="Teasdale, Chloe A" uniqKey="Teasdale C" first="Chloe A" last="Teasdale">Chloe A. Teasdale</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Sogaula, Nonzwakazi" sort="Sogaula, Nonzwakazi" uniqKey="Sogaula N" first="Nonzwakazi" last="Sogaula">Nonzwakazi Sogaula</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Yuengling, Katharine A" sort="Yuengling, Katharine A" uniqKey="Yuengling K" first="Katharine A" last="Yuengling">Katharine A. Yuengling</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Peters, Zachary J" sort="Peters, Zachary J" uniqKey="Peters Z" first="Zachary J" last="Peters">Zachary J. Peters</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Mutiti, Anthony" sort="Mutiti, Anthony" uniqKey="Mutiti A" first="Anthony" last="Mutiti">Anthony Mutiti</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author><author><name sortKey="Pepeta, Lungile" sort="Pepeta, Lungile" uniqKey="Pepeta L" first="Lungile" last="Pepeta">Lungile Pepeta</name><affiliation><nlm:affiliation>Port Elizabeth Hospital Complex, Department of Paediatrics, Port Elizabeth, South Africa.</nlm:affiliation></affiliation></author><author><name sortKey="Abrams, Elaine J" sort="Abrams, Elaine J" uniqKey="Abrams E" first="Elaine J" last="Abrams">Elaine J. Abrams</name><affiliation><nlm:affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of the International AIDS Society</title><idno type="eISSN">1758-2652</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">28691440</PMID><DateCreated><Year>2017</Year><Month>07</Month><Day>10</Day></DateCreated><DateRevised><Year>2017</Year><Month>09</Month><Day>27</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1758-2652</ISSN><JournalIssue CitedMedium="Internet"><Volume>20</Volume><Issue>1</Issue><PubDate><Year>2017</Year><Month>06</Month><Day>28</Day></PubDate></JournalIssue><Title>Journal of the International AIDS Society</Title><ISOAbbreviation>J Int AIDS Soc</ISOAbbreviation></Journal><ArticleTitle>High risk of loss to follow-up among South African children on ART during transfer, a retrospective cohort analysis with community tracing.</ArticleTitle><Pagination><MedlinePgn>21748</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.7448/IAS.20.1.21748</ELocationID><Abstract><AbstractText Label="INTRODUCTION">Decentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa.</AbstractText><AbstractText Label="METHODS">Electronic medical records for all children 0-15 years initiating ART at Dora Nginza Hospital (DNH) in Port Elizabeth, South Africa January 2004 to September 2015 were examined. Records for children transferred to primary and community clinics were searched at 16 health facilities to identify children with successful (at least one recorded visit) and unsuccessful transfer (no visits). We identified all children lost to follow-up (LTF) after ART initiation: those LTF at DNH (no visit >6 months), children with unsuccessful transfer, and children LTF after successful transfer (no visit >6 months). Community tracing was conducted to locate caregivers of children LTF and electronic laboratory data were searched to measure reengagement in care, including silent transfers.</AbstractText><AbstractText Label="RESULTS">1,582 children initiated ART at median age of 4 years [interquartile range (IQR): 1-8] and median CD4+ of 278 cells/mm(3) [IQR: 119-526]. A total of 901 (57.0%) children were transferred, 644 (71.5%) to study facilities; 433 (67.2%) children had successful transfer and 211 (32.8%) had unsuccessful transfer. In total, 399 children were LTF: 105 (26.3%) from DNH, 211 (52.9%) through unsuccessful transfer and 83 (20.8%) following successful transfer. Community tracing was conducted for 120 (30.1%) of 399 children LTF and 66 (55.0%) caregivers were located and interviewed. Four children had died. Among 62 children still alive, 8 (12.9%) were reported to not be in care or taking ART and 18 (29.0%) were also not taking ART. Overall, 65 (16.3%) of 399 children LTF had a laboratory result within 18 months of their last visit indicating silent transfer and 112 (28.1%) had lab results from 2015 to 2016 indicating current care.</AbstractText><AbstractText Label="CONCLUSION">We found that only two-thirds of children on ART transferred to primary and community health clinics had successful transfer. These findings suggest that transfer is a particularly vulnerable step in the paediatric HIV care cascade.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Teasdale</LastName><ForeName>Chloe A</ForeName><Initials>CA</Initials><AffiliationInfo><Affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University New York, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sogaula</LastName><ForeName>Nonzwakazi</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yuengling</LastName><ForeName>Katharine A</ForeName><Initials>KA</Initials><AffiliationInfo><Affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Peters</LastName><ForeName>Zachary J</ForeName><Initials>ZJ</Initials><AffiliationInfo><Affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mutiti</LastName><ForeName>Anthony</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pepeta</LastName><ForeName>Lungile</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Port Elizabeth Hospital Complex, Department of Paediatrics, Port Elizabeth, South Africa.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Nelson Mandela Metropolitan University, Faculty of Health Sciences, Port Elizabeth, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Abrams</LastName><ForeName>Elaine J</ForeName><Initials>EJ</Initials><AffiliationInfo><Affiliation>ICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Department of Epidemiology, Mailman School of Public Health, Columbia University New York, New York, NY, USA.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>College of Physicians & Surgeons, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>J Int AIDS Soc</MedlineTA><NlmUniqueID>101478566</NlmUniqueID><ISSNLinking>1758-2652</ISSNLinking></MedlineJournalInfo><CommentsCorrectionsList><CommentsCorrections 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PubStatus="medline"><Year>2017</Year><Month>7</Month><Day>12</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">28691440</ArticleId><ArticleId IdType="doi">10.7448/IAS.20.1.21748</ArticleId><ArticleId IdType="pmc">PMC5515030</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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