Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: a systematic review protocol
Identifieur interne : 000289 ( Pmc/Curation ); précédent : 000288; suivant : 000290Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: a systematic review protocol
Auteurs : Annesinah Hlengiwe Moloi [Afrique du Sud] ; David Watkins [Afrique du Sud, États-Unis] ; Mark E. Engel [Afrique du Sud] ; Sumaya Mall [Afrique du Sud] ; Liesl Zühlke [Afrique du Sud]Source :
- BMJ Open [ 2044-6055 ] ; 2016.
Abstract
Rheumatic heart disease (RHD) is a chronic disease affecting the heart valves, secondary to group A streptococcal infection (GAS) and subsequent acute rheumatic fever (ARF). However, RHD cure and preventative measures are inextricably linked with socioeconomic development, as the disease mainly affects children and young adults living in poverty. In order to address RHD, public health officials and health policymakers require up-to-date knowledge on the epidemiology of GAS, ARF and RHD, as well as the existing enablers and gaps in delivery of evidence-based care for these conditions. We propose to conduct a systematic review to assess the literature comprehensively, synthesising all existing quantitative and qualitative data relating to RHD in Africa.
We plan to conduct a comprehensive literature search using a number of databases and reference lists of relevant articles published from January 1995 to December 2015. Two evaluators will independently review and extract data from each article. Additionally, we will assess overall study quality and risk of bias, using the Newcastle-Ottawa Scale and the Critical Appraisal Skills Programme criteria for quantitative and qualitative studies, respectively. We will meta-analyse estimates of prevalence, incidence, case fatality and mortality for each of the conditions separately for each country. Qualitative meta-analysis will be conducted for facilitators and barriers in RHD health access. Lastly, we will create a list of key stakeholders. This protocol is registered in the PROSPERO International Prospective Register of systematic reviews, registration number CRD42016032852.
The information provided by this review will inform and assist relevant stakeholders in identifying key areas of intervention, and designing and implementing evidence-based programmes and policies at the local and regional level. With slight modifications (ie, to the country terms in the search strategy), this protocol can be used as part of a needs assessment in any endemic country.
Url:
DOI: 10.1136/bmjopen-2016-011266
PubMed: 27207627
PubMed Central: 4885440
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: a systematic review protocol</title><author><name sortKey="Moloi, Annesinah Hlengiwe" sort="Moloi, Annesinah Hlengiwe" uniqKey="Moloi A" first="Annesinah Hlengiwe" last="Moloi">Annesinah Hlengiwe Moloi</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Watkins, David" sort="Watkins, David" uniqKey="Watkins D" first="David" last="Watkins">David Watkins</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Medicine</addr-line>,<institution>University of Washington</institution>,<addr-line>Seattle, Washington</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Engel, Mark E" sort="Engel, Mark E" uniqKey="Engel M" first="Mark E" last="Engel">Mark E. Engel</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mall, Sumaya" sort="Mall, Sumaya" uniqKey="Mall S" first="Sumaya" last="Mall">Sumaya Mall</name><affiliation wicri:level="1"><nlm:aff id="af3"><addr-line>Department of Psychiatry</addr-line>,<institution>Groote Schuur Hospital Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Centre for Evidence Based Health Care</addr-line>,<institution>Faculty of Health Sciences</institution>,<addr-line>Stellenbosch University, Stellenbosch</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zuhlke, Liesl" sort="Zuhlke, Liesl" uniqKey="Zuhlke L" first="Liesl" last="Zühlke">Liesl Zühlke</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af5"><addr-line>Department of Paediatrics</addr-line>,<institution>Red Cross War Memorial Children's Hospital</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">27207627</idno><idno type="pmc">4885440</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4885440</idno><idno type="RBID">PMC:4885440</idno><idno type="doi">10.1136/bmjopen-2016-011266</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000289</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000289</idno><idno type="wicri:Area/Pmc/Curation">000289</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000289</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: a systematic review protocol</title><author><name sortKey="Moloi, Annesinah Hlengiwe" sort="Moloi, Annesinah Hlengiwe" uniqKey="Moloi A" first="Annesinah Hlengiwe" last="Moloi">Annesinah Hlengiwe Moloi</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Watkins, David" sort="Watkins, David" uniqKey="Watkins D" first="David" last="Watkins">David Watkins</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af2"><addr-line>Department of Medicine</addr-line>,<institution>University of Washington</institution>,<addr-line>Seattle, Washington</addr-line>,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Engel, Mark E" sort="Engel, Mark E" uniqKey="Engel M" first="Mark E" last="Engel">Mark E. Engel</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Mall, Sumaya" sort="Mall, Sumaya" uniqKey="Mall S" first="Sumaya" last="Mall">Sumaya Mall</name><affiliation wicri:level="1"><nlm:aff id="af3"><addr-line>Department of Psychiatry</addr-line>,<institution>Groote Schuur Hospital Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Centre for Evidence Based Health Care</addr-line>,<institution>Faculty of Health Sciences</institution>,<addr-line>Stellenbosch University, Stellenbosch</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zuhlke, Liesl" sort="Zuhlke, Liesl" uniqKey="Zuhlke L" first="Liesl" last="Zühlke">Liesl Zühlke</name><affiliation wicri:level="1"><nlm:aff id="af1"><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="af5"><addr-line>Department of Paediatrics</addr-line>,<institution>Red Cross War Memorial Children's Hospital</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">BMJ Open</title><idno type="eISSN">2044-6055</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Introduction</title><p>Rheumatic heart disease (RHD) is a chronic disease affecting the heart valves, secondary to group A streptococcal infection (GAS) and subsequent acute rheumatic fever (ARF). However, RHD cure and preventative measures are inextricably linked with socioeconomic development, as the disease mainly affects children and young adults living in poverty. In order to address RHD, public health officials and health policymakers require up-to-date knowledge on the epidemiology of GAS, ARF and RHD, as well as the existing enablers and gaps in delivery of evidence-based care for these conditions. We propose to conduct a systematic review to assess the literature comprehensively, synthesising all existing quantitative and qualitative data relating to RHD in Africa.</p></sec><sec><title>Methods and analysis</title><p>We plan to conduct a comprehensive literature search using a number of databases and reference lists of relevant articles published from January 1995 to December 2015. Two evaluators will independently review and extract data from each article. Additionally, we will assess overall study quality and risk of bias, using the Newcastle-Ottawa Scale and the Critical Appraisal Skills Programme criteria for quantitative and qualitative studies, respectively. We will meta-analyse estimates of prevalence, incidence, case fatality and mortality for each of the conditions separately for each country. Qualitative meta-analysis will be conducted for facilitators and barriers in RHD health access. Lastly, we will create a list of key stakeholders. This protocol is registered in the PROSPERO International Prospective Register of systematic reviews, registration number CRD42016032852.</p></sec><sec><title>Ethics and dissemination</title><p>The information provided by this review will inform and assist relevant stakeholders in identifying key areas of intervention, and designing and implementing evidence-based programmes and policies at the local and regional level. With slight modifications (ie, to the country terms in the search strategy), this protocol can be used as part of a needs assessment in any endemic country.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Marijon, E" uniqKey="Marijon E">E Marijon</name></author><author><name sortKey="Mirabel, M" uniqKey="Mirabel M">M Mirabel</name></author><author><name sortKey="Celermajer, Ds" uniqKey="Celermajer D">DS Celermajer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carapetis, Jr" uniqKey="Carapetis J">JR Carapetis</name></author><author><name sortKey="Mcdonald, M" uniqKey="Mcdonald M">M McDonald</name></author><author><name sortKey="Wilson, Nj" uniqKey="Wilson N">NJ Wilson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guilherme, L" uniqKey="Guilherme L">L Guilherme</name></author><author><name sortKey="Kalil, J" uniqKey="Kalil J">J 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<front><journal-meta><journal-id journal-id-type="nlm-ta">BMJ Open</journal-id><journal-id journal-id-type="iso-abbrev">BMJ Open</journal-id><journal-id journal-id-type="hwp">bmjopen</journal-id><journal-id journal-id-type="publisher-id">bmjopen</journal-id><journal-title-group><journal-title>BMJ Open</journal-title></journal-title-group><issn pub-type="epub">2044-6055</issn><publisher><publisher-name>BMJ Publishing Group</publisher-name><publisher-loc>BMA House, Tavistock Square, London, WC1H 9JR</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">27207627</article-id><article-id pub-id-type="pmc">4885440</article-id><article-id pub-id-type="publisher-id">bmjopen-2016-011266</article-id><article-id pub-id-type="doi">10.1136/bmjopen-2016-011266</article-id><article-categories><subj-group subj-group-type="heading"><subject>Cardiovascular Medicine</subject><subj-group><subject>Protocol</subject></subj-group></subj-group><subj-group subj-group-type="hwp-journal-coll"><subject>1506</subject><subject>1683</subject><subject>1694</subject><subject>1692</subject><subject>1722</subject><subject>1683</subject><subject>1699</subject></subj-group></article-categories><title-group><article-title>Epidemiology, health systems and stakeholders in rheumatic heart disease in Africa: a systematic review protocol</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Moloi</surname><given-names>Annesinah Hlengiwe</given-names></name><xref ref-type="aff" rid="af1">1</xref></contrib><contrib contrib-type="author"><name><surname>Watkins</surname><given-names>David</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af2">2</xref></contrib><contrib contrib-type="author"><name><surname>Engel</surname><given-names>Mark E</given-names></name><xref ref-type="aff" rid="af1">1</xref></contrib><contrib contrib-type="author"><name><surname>Mall</surname><given-names>Sumaya</given-names></name><xref ref-type="aff" rid="af3">3</xref><xref ref-type="aff" rid="af4">4</xref></contrib><contrib contrib-type="author"><name><surname>Zühlke</surname><given-names>Liesl</given-names></name><xref ref-type="aff" rid="af1">1</xref><xref ref-type="aff" rid="af5">5</xref></contrib></contrib-group><aff id="af1"><label>1</label><addr-line>Department of Medicine, Faculty of Health Sciences</addr-line>,<institution>University of Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></aff><aff id="af2"><label>2</label><addr-line>Department of Medicine</addr-line>,<institution>University of Washington</institution>,<addr-line>Seattle, Washington</addr-line>,<country>USA</country></aff><aff id="af3"><label>3</label><addr-line>Department of Psychiatry</addr-line>,<institution>Groote Schuur Hospital Cape Town</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></aff><aff id="af4"><label>4</label><addr-line>Centre for Evidence Based Health Care</addr-line>,<institution>Faculty of Health Sciences</institution>,<addr-line>Stellenbosch University, Stellenbosch</addr-line>,<country>South Africa</country></aff><aff id="af5"><label>5</label><addr-line>Department of Paediatrics</addr-line>,<institution>Red Cross War Memorial Children's Hospital</institution>,<addr-line>Cape Town</addr-line>,<country>South Africa</country></aff><author-notes><corresp><label>Correspondence to</label> Dr Liesl Zühlke; <email>liesl.zuhlke@uct.ac.za</email></corresp></author-notes><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>5</month><year>2016</year></pub-date><volume>6</volume><issue>5</issue><elocation-id>e011266</elocation-id><history><date date-type="received"><day>25</day><month>1</month><year>2016</year></date><date date-type="rev-recd"><day>31</day><month>3</month><year>2016</year></date><date date-type="accepted"><day>28</day><month>4</month><year>2016</year></date></history><permissions><copyright-statement>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/</copyright-statement><copyright-year>2016</copyright-year><license license-type="open-access"><license-p>This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: <ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/">http://creativecommons.org/licenses/by-nc/4.0/</ext-link></license-p></license></permissions><self-uri xlink:title="pdf" xlink:href="bmjopen-2016-011266.pdf"></self-uri><abstract><sec><title>Introduction</title><p>Rheumatic heart disease (RHD) is a chronic disease affecting the heart valves, secondary to group A streptococcal infection (GAS) and subsequent acute rheumatic fever (ARF). However, RHD cure and preventative measures are inextricably linked with socioeconomic development, as the disease mainly affects children and young adults living in poverty. In order to address RHD, public health officials and health policymakers require up-to-date knowledge on the epidemiology of GAS, ARF and RHD, as well as the existing enablers and gaps in delivery of evidence-based care for these conditions. We propose to conduct a systematic review to assess the literature comprehensively, synthesising all existing quantitative and qualitative data relating to RHD in Africa.</p></sec><sec><title>Methods and analysis</title><p>We plan to conduct a comprehensive literature search using a number of databases and reference lists of relevant articles published from January 1995 to December 2015. Two evaluators will independently review and extract data from each article. Additionally, we will assess overall study quality and risk of bias, using the Newcastle-Ottawa Scale and the Critical Appraisal Skills Programme criteria for quantitative and qualitative studies, respectively. We will meta-analyse estimates of prevalence, incidence, case fatality and mortality for each of the conditions separately for each country. Qualitative meta-analysis will be conducted for facilitators and barriers in RHD health access. Lastly, we will create a list of key stakeholders. This protocol is registered in the PROSPERO International Prospective Register of systematic reviews, registration number CRD42016032852.</p></sec><sec><title>Ethics and dissemination</title><p>The information provided by this review will inform and assist relevant stakeholders in identifying key areas of intervention, and designing and implementing evidence-based programmes and policies at the local and regional level. With slight modifications (ie, to the country terms in the search strategy), this protocol can be used as part of a needs assessment in any endemic country.</p></sec></abstract><kwd-group><kwd>Group A Streptococcus</kwd><kwd>Acute Rheumatic fever,</kwd><kwd>Rheumatic heart disease</kwd><kwd>Health systems</kwd><kwd>stakeholders</kwd><kwd>Africa</kwd></kwd-group><funding-group specific-use="FundRef"><award-group id="funding-1"><funding-source><institution-wrap><institution>Medtronic</institution><institution-id>http://dx.doi.org/10.13039/100004374</institution-id></institution-wrap></funding-source></award-group></funding-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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