Partner age-disparity and HIV incidence risk for older women in rural South Africa
Identifieur interne : 002010 ( Pmc/Corpus ); précédent : 002009; suivant : 002011Partner age-disparity and HIV incidence risk for older women in rural South Africa
Auteurs : Guy Harling ; Marie-Louise Newell ; Frank Tanser ; Till B RnighausenSource :
- AIDS and behavior [ 1090-7165 ] ; 2015.
Abstract
While sexual partner age disparity is frequently considered as a potential risk factor for HIV amongst young women in Africa, no research has addressed this question amongst older women. Our aim was thus to determine whether sex partner age disparity was associated with subsequent HIV acquisition in women aged over 30.
To achieve this aim we conducted a quantitative analysis of a population-based, open cohort of women in rural KwaZulu-Natal, South Africa (n=1,737) using Cox proportional hazards models.
As partner age rose, HIV acquisition risk fell significantly: compared to a same-aged partner, a five-year older partner was associated with a one-third reduction (hazard ratio [HR]: 0.63, 95%CI: 0.52–0.76) and a ten-year older partner with a one-half reduction (HR: 0.48, 95%CI: 0.35–0.67). This result was neither confounded nor effect-modified by women’s age or socio-demographic factors.
These findings suggest that existing HIV risk-reduction campaigns warning young women about partnering with older men may be inappropriate for older women. HIV prevention strategies interventions specifically tailored to older women are needed.
Url:
DOI: 10.1007/s10461-014-0952-3
PubMed: 25670473
PubMed Central: 4506232
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Our aim was thus to determine whether sex partner age disparity was associated with subsequent HIV acquisition in women aged over 30.</p><sec id="S1"><title>Methods</title><p id="P2">To achieve this aim we conducted a quantitative analysis of a population-based, open cohort of women in rural KwaZulu-Natal, South Africa (n=1,737) using Cox proportional hazards models.</p></sec><sec id="S2"><title>Results</title><p id="P3">As partner age rose, HIV acquisition risk fell significantly: compared to a same-aged partner, a five-year older partner was associated with a one-third reduction (hazard ratio [HR]: 0.63, 95%CI: 0.52–0.76) and a ten-year older partner with a one-half reduction (HR: 0.48, 95%CI: 0.35–0.67). This result was neither confounded nor effect-modified by women’s age or socio-demographic factors.</p></sec><sec id="S3"><title>Conclusions</title><p id="P4">These findings suggest that existing HIV risk-reduction campaigns warning young women about partnering with older men may be inappropriate for older women. HIV prevention strategies interventions specifically tailored to older women are needed.</p></sec></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9712133</journal-id><journal-id journal-id-type="pubmed-jr-id">21042</journal-id><journal-id journal-id-type="nlm-ta">AIDS Behav</journal-id><journal-id journal-id-type="iso-abbrev">AIDS Behav</journal-id><journal-title-group><journal-title>AIDS and behavior</journal-title></journal-title-group><issn pub-type="ppub">1090-7165</issn><issn pub-type="epub">1573-3254</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25670473</article-id><article-id pub-id-type="pmc">4506232</article-id><article-id pub-id-type="doi">10.1007/s10461-014-0952-3</article-id><article-id pub-id-type="manuscript">NIHMS648627</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Partner age-disparity and HIV incidence risk for older women in rural South Africa</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Harling</surname><given-names>Guy</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Newell</surname><given-names>Marie-Louise</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Tanser</surname><given-names>Frank</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Bärnighausen</surname><given-names>Till</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib></contrib-group><aff id="A1"><label>1</label>Department of Global Health and Population, Harvard School of Public Health, Boston MA</aff><aff id="A2"><label>2</label>Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Mtubatuba, South Africa</aff><aff id="A3"><label>3</label>Faculty of Medicine, University of Southampton, Southampton, UK</aff><author-notes><corresp id="FN1">Corresponding author: Guy Harling. Department of Global Health and Population, Harvard School of Public Health, 665 Huntington Avenue, Boston MA, 02115. Telephone: +1 617 432 1232. Fax: +1 617 432 6733; <email>gharling@hsph.harvard.edu</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>12</day><month>12</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>7</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>10</month><year>2015</year></pub-date><volume>19</volume><issue>7</issue><fpage>1317</fpage><lpage>1326</lpage><pmc-comment>elocation-id from pubmed: 10.1007/s10461-014-0952-3</pmc-comment>
<abstract><p id="P1">While sexual partner age disparity is frequently considered as a potential risk factor for HIV amongst young women in Africa, no research has addressed this question amongst older women. Our aim was thus to determine whether sex partner age disparity was associated with subsequent HIV acquisition in women aged over 30.</p><sec id="S1"><title>Methods</title><p id="P2">To achieve this aim we conducted a quantitative analysis of a population-based, open cohort of women in rural KwaZulu-Natal, South Africa (n=1,737) using Cox proportional hazards models.</p></sec><sec id="S2"><title>Results</title><p id="P3">As partner age rose, HIV acquisition risk fell significantly: compared to a same-aged partner, a five-year older partner was associated with a one-third reduction (hazard ratio [HR]: 0.63, 95%CI: 0.52–0.76) and a ten-year older partner with a one-half reduction (HR: 0.48, 95%CI: 0.35–0.67). This result was neither confounded nor effect-modified by women’s age or socio-demographic factors.</p></sec><sec id="S3"><title>Conclusions</title><p id="P4">These findings suggest that existing HIV risk-reduction campaigns warning young women about partnering with older men may be inappropriate for older women. HIV prevention strategies interventions specifically tailored to older women are needed.</p></sec></abstract><kwd-group><kwd>HIV acquisition</kwd><kwd>age disparities</kwd><kwd>South Africa</kwd><kwd>women</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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