Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study
Identifieur interne : 002003 ( Pmc/Corpus ); précédent : 002002; suivant : 002004Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study
Auteurs : Peter K. Olds ; Julius P. Kiwanuka ; Norma C. Ware ; Alexander C. Tsai ; Jessica E. HabererSource :
- AIDS and behavior [ 1090-7165 ] ; 2015.
Abstract
High adherence is critical for achieving clinical benefits of HIV antiretroviral therapy (ART) and particularly challenging for children. We conducted 35 qualitative interviews with caregivers of HIV-infected Ugandan children who were followed in a longitudinal study of real-time ART adherence monitoring; 18 participants had undetectable HIV RNA, while 17 had detectable virus. Interviews blinded to viral suppression status elicited information on adherence experiences, barriers and facilitators to adherence, and social support. Using an inductive content analytic approach, we identified ‘lack of resources,’ ‘Lazarus effect,’ ‘caregiver's sense of obligation and commitment,’ and ‘child's personal responsibility’ as categories of influence on adherence, and defined types of caregiver social support. Among children with viral suppression, high hopes for the child's future and ready access to private instrumental support appeared particularly important. These findings suggest clinical counseling should explore caregivers' views of their children's futures and ability to access support in overcoming adherence barriers.
Url:
DOI: 10.1007/s10461-014-0924-7
PubMed: 25323679
PubMed Central: 4393764
Links to Exploration step
PMC:4393764Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study</title><author><name sortKey="Olds, Peter K" sort="Olds, Peter K" uniqKey="Olds P" first="Peter K." last="Olds">Peter K. Olds</name></author><author><name sortKey="Kiwanuka, Julius P" sort="Kiwanuka, Julius P" uniqKey="Kiwanuka J" first="Julius P." last="Kiwanuka">Julius P. Kiwanuka</name></author><author><name sortKey="Ware, Norma C" sort="Ware, Norma C" uniqKey="Ware N" first="Norma C." last="Ware">Norma C. Ware</name></author><author><name sortKey="Tsai, Alexander C" sort="Tsai, Alexander C" uniqKey="Tsai A" first="Alexander C." last="Tsai">Alexander C. Tsai</name></author><author><name sortKey="Haberer, Jessica E" sort="Haberer, Jessica E" uniqKey="Haberer J" first="Jessica E." last="Haberer">Jessica E. Haberer</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25323679</idno><idno type="pmc">4393764</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393764</idno><idno type="RBID">PMC:4393764</idno><idno type="doi">10.1007/s10461-014-0924-7</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">002003</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002003</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study</title><author><name sortKey="Olds, Peter K" sort="Olds, Peter K" uniqKey="Olds P" first="Peter K." last="Olds">Peter K. Olds</name></author><author><name sortKey="Kiwanuka, Julius P" sort="Kiwanuka, Julius P" uniqKey="Kiwanuka J" first="Julius P." last="Kiwanuka">Julius P. Kiwanuka</name></author><author><name sortKey="Ware, Norma C" sort="Ware, Norma C" uniqKey="Ware N" first="Norma C." last="Ware">Norma C. Ware</name></author><author><name sortKey="Tsai, Alexander C" sort="Tsai, Alexander C" uniqKey="Tsai A" first="Alexander C." last="Tsai">Alexander C. Tsai</name></author><author><name sortKey="Haberer, Jessica E" sort="Haberer, Jessica E" uniqKey="Haberer J" first="Jessica E." last="Haberer">Jessica E. Haberer</name></author></analytic><series><title level="j">AIDS and behavior</title><idno type="ISSN">1090-7165</idno><idno type="eISSN">1573-3254</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">High adherence is critical for achieving clinical benefits of HIV antiretroviral therapy (ART) and particularly challenging for children. We conducted 35 qualitative interviews with caregivers of HIV-infected Ugandan children who were followed in a longitudinal study of real-time ART adherence monitoring; 18 participants had undetectable HIV RNA, while 17 had detectable virus. Interviews blinded to viral suppression status elicited information on adherence experiences, barriers and facilitators to adherence, and social support. Using an inductive content analytic approach, we identified ‘lack of resources,’ ‘Lazarus effect,’ ‘caregiver's sense of obligation and commitment,’ and ‘child's personal responsibility’ as categories of influence on adherence, and defined types of caregiver social support. Among children with viral suppression, high hopes for the child's future and ready access to private instrumental support appeared particularly important. These findings suggest clinical counseling should explore caregivers' views of their children's futures and ability to access support in overcoming adherence barriers.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">9712133</journal-id><journal-id journal-id-type="pubmed-jr-id">21042</journal-id><journal-id journal-id-type="nlm-ta">AIDS Behav</journal-id><journal-id journal-id-type="iso-abbrev">AIDS Behav</journal-id><journal-title-group><journal-title>AIDS and behavior</journal-title></journal-title-group><issn pub-type="ppub">1090-7165</issn><issn pub-type="epub">1573-3254</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25323679</article-id><article-id pub-id-type="pmc">4393764</article-id><article-id pub-id-type="doi">10.1007/s10461-014-0924-7</article-id><article-id pub-id-type="manuscript">NIHMS636127</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Olds</surname><given-names>Peter K.</given-names></name><aff id="A1">Harvard Medical School, Boston, MA, USA</aff></contrib><contrib contrib-type="author"><name><surname>Kiwanuka</surname><given-names>Julius P.</given-names></name><aff id="A2">Department of Paediatrics, Mbarara University of Science and Technology, Mbarara, Uganda</aff></contrib><contrib contrib-type="author"><name><surname>Ware</surname><given-names>Norma C.</given-names></name><aff id="A3">Department of Global Health and Social Medicine, Department of Psychiatry, Harvard Medical School, Boston, MA, USA</aff></contrib><contrib contrib-type="author"><name><surname>Tsai</surname><given-names>Alexander C.</given-names></name><aff id="A4">Department of Psychiatry and Center for Global Health, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA</aff></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Haberer</surname><given-names>Jessica E.</given-names></name><email>jhaberer@partners.org</email><aff id="A5">Department of Medicine, Harvard Medical School, Boston, MA, USA;Department of Medicine and Center for Global Health, MGH Center for Global Health, Massachusetts General Hospital, 100 Cambridge St., 15th Floor, Boston, MA 02114, USA</aff></contrib></contrib-group><pub-date pub-type="nihms-submitted"><day>4</day><month>11</month><year>2014</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2015</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>4</month><year>2016</year></pub-date><volume>19</volume><issue>4</issue><fpage>584</fpage><lpage>593</lpage><pmc-comment>elocation-id from pubmed: 10.1007/s10461-014-0924-7</pmc-comment>
<permissions><copyright-statement>© Springer Science+Business Media New York 2014</copyright-statement><copyright-year>2014</copyright-year></permissions><abstract><p id="P1">High adherence is critical for achieving clinical benefits of HIV antiretroviral therapy (ART) and particularly challenging for children. We conducted 35 qualitative interviews with caregivers of HIV-infected Ugandan children who were followed in a longitudinal study of real-time ART adherence monitoring; 18 participants had undetectable HIV RNA, while 17 had detectable virus. Interviews blinded to viral suppression status elicited information on adherence experiences, barriers and facilitators to adherence, and social support. Using an inductive content analytic approach, we identified ‘lack of resources,’ ‘Lazarus effect,’ ‘caregiver's sense of obligation and commitment,’ and ‘child's personal responsibility’ as categories of influence on adherence, and defined types of caregiver social support. Among children with viral suppression, high hopes for the child's future and ready access to private instrumental support appeared particularly important. These findings suggest clinical counseling should explore caregivers' views of their children's futures and ability to access support in overcoming adherence barriers.</p></abstract><kwd-group><kwd>Antiretroviral therapy</kwd><kwd>Human immunodeficiency virus</kwd><kwd>Adherence</kwd><kwd>Children</kwd><kwd>Uganda</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002003 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 002003 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaSubSaharaV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé= PMC:4393764
|texte= Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/RBID.i -Sk "pubmed:25323679" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a SidaSubSaharaV1
| This area was generated with Dilib version V0.6.32. |  |