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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Prospective study of the mental health consequences of sexual violence among women living with HIV in rural Uganda</title><author><name sortKey="Tsai, Alexander C" sort="Tsai, Alexander C" uniqKey="Tsai A" first="Alexander C." last="Tsai">Alexander C. Tsai</name><affiliation><nlm:aff id="A1"> Massachusetts General Hospital, Boston, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Wolfe, William R" sort="Wolfe, William R" uniqKey="Wolfe W" first="William R." last="Wolfe">William R. Wolfe</name><affiliation><nlm:aff id="A3"> Department of Psychiatry, University of California at San Francisco (UCSF), San Francisco, USA</nlm:aff></affiliation></author><author><name sortKey="Kumbakumba, Elias" sort="Kumbakumba, Elias" uniqKey="Kumbakumba E" first="Elias" last="Kumbakumba">Elias Kumbakumba</name><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Kawuma, Annet" sort="Kawuma, Annet" uniqKey="Kawuma A" first="Annet" last="Kawuma">Annet Kawuma</name><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Hunt, Peter W" sort="Hunt, Peter W" uniqKey="Hunt P" first="Peter W." last="Hunt">Peter W. Hunt</name><affiliation><nlm:aff id="A4"> Positive Health Program, San Francisco General Hospital at UCSF, San Francisco, UCA</nlm:aff></affiliation></author><author><name sortKey="Martin, Jeffrey N" sort="Martin, Jeffrey N" uniqKey="Martin J" first="Jeffrey N." last="Martin">Jeffrey N. Martin</name><affiliation><nlm:aff id="A5"> UCSF Department of Epidemiology and Biostatistics, San Francisco, UCA</nlm:aff></affiliation></author><author><name sortKey="Bangsberg, David R" sort="Bangsberg, David R" uniqKey="Bangsberg D" first="David R." last="Bangsberg">David R. Bangsberg</name><affiliation><nlm:aff id="A1"> Massachusetts General Hospital, Boston, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Weiser, Sheri D" sort="Weiser, Sheri D" uniqKey="Weiser S" first="Sheri D." last="Weiser">Sheri D. Weiser</name><affiliation><nlm:aff id="A4"> Positive Health Program, San Francisco General Hospital at UCSF, San Francisco, UCA</nlm:aff></affiliation><affiliation><nlm:aff id="A6"> Center for AIDS Prevention Studies, UCSF Department of Medicine, San Francisco, USA</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25586914</idno><idno type="pmc">4500676</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500676</idno><idno type="RBID">PMC:4500676</idno><idno type="doi">10.1177/0886260514567966</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">001D14</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D14</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Prospective study of the mental health consequences of sexual violence among women living with HIV in rural Uganda</title><author><name sortKey="Tsai, Alexander C" sort="Tsai, Alexander C" uniqKey="Tsai A" first="Alexander C." last="Tsai">Alexander C. Tsai</name><affiliation><nlm:aff id="A1"> Massachusetts General Hospital, Boston, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Wolfe, William R" sort="Wolfe, William R" uniqKey="Wolfe W" first="William R." last="Wolfe">William R. Wolfe</name><affiliation><nlm:aff id="A3"> Department of Psychiatry, University of California at San Francisco (UCSF), San Francisco, USA</nlm:aff></affiliation></author><author><name sortKey="Kumbakumba, Elias" sort="Kumbakumba, Elias" uniqKey="Kumbakumba E" first="Elias" last="Kumbakumba">Elias Kumbakumba</name><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Kawuma, Annet" sort="Kawuma, Annet" uniqKey="Kawuma A" first="Annet" last="Kawuma">Annet Kawuma</name><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Hunt, Peter W" sort="Hunt, Peter W" uniqKey="Hunt P" first="Peter W." last="Hunt">Peter W. Hunt</name><affiliation><nlm:aff id="A4"> Positive Health Program, San Francisco General Hospital at UCSF, San Francisco, UCA</nlm:aff></affiliation></author><author><name sortKey="Martin, Jeffrey N" sort="Martin, Jeffrey N" uniqKey="Martin J" first="Jeffrey N." last="Martin">Jeffrey N. Martin</name><affiliation><nlm:aff id="A5"> UCSF Department of Epidemiology and Biostatistics, San Francisco, UCA</nlm:aff></affiliation></author><author><name sortKey="Bangsberg, David R" sort="Bangsberg, David R" uniqKey="Bangsberg D" first="David R." last="Bangsberg">David R. Bangsberg</name><affiliation><nlm:aff id="A1"> Massachusetts General Hospital, Boston, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A2"> Mbarara University of Science and Technology, Mbarara, Uganda</nlm:aff></affiliation></author><author><name sortKey="Weiser, Sheri D" sort="Weiser, Sheri D" uniqKey="Weiser S" first="Sheri D." last="Weiser">Sheri D. Weiser</name><affiliation><nlm:aff id="A4"> Positive Health Program, San Francisco General Hospital at UCSF, San Francisco, UCA</nlm:aff></affiliation><affiliation><nlm:aff id="A6"> Center for AIDS Prevention Studies, UCSF Department of Medicine, San Francisco, USA</nlm:aff></affiliation></author></analytic><series><title level="j">Journal of interpersonal violence</title><idno type="ISSN">0886-2605</idno><idno type="eISSN">1552-6518</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The association between sexual violence and depression is well known, but the temporal aspects of the association have not been well established. We analyzed data from a cohort of 173 HIV-positive women in rural Uganda who were interviewed every 3 months for a median of 1.8 years of follow-up. The method of generalized estimating equations (GEE) was used to model the marginal expectation of depression symptom severity (Hopkins Symptom Checklist for Depression), mental health–related quality of life (MOS-HIV Mental Health Summary), and heavy drinking (Alcohol Use Disorders Identification Test) as a function of self-reported forced-sex victimization in the 3 months prior to interview. Estimates were adjusted for variables known to confound the association between victimization and mental health status. To assess any potential reciprocal relationships, we reversed the temporal ordering of the exposures and outcomes and refitted similar GEE models. In multivariable analyses, victimization was associated with greater depression symptom severity (<italic>b</italic> = 0.17; 95% CI = [0.02, 0.33]) and lower mental health–related quality of life (<italic>b</italic> = −5.65; 95% CI = [−9.34, −1.96]), as well as increased risks for probable depression (adjusted relative risk [ARR] = 1.58; 95% CI = [1.01, 2.49) and heavy drinking (ARR = 3.99; 95% CI = [1.84, 8.63]). We did not find strong evidence of a reciprocal relationship. Our findings suggest that forced sex is associated with adverse mental health outcomes among HIV-positive women in rural Uganda. Given the substantial mental health–related impacts of victimization, effective health sector responses are needed.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8700910</journal-id><journal-id journal-id-type="pubmed-jr-id">28254</journal-id><journal-id journal-id-type="nlm-ta">J Interpers Violence</journal-id><journal-id journal-id-type="iso-abbrev">J Interpers Violence</journal-id><journal-title-group><journal-title>Journal of interpersonal violence</journal-title></journal-title-group><issn pub-type="ppub">0886-2605</issn><issn pub-type="epub">1552-6518</issn></journal-meta><article-meta><article-id pub-id-type="pmid">25586914</article-id><article-id pub-id-type="pmc">4500676</article-id><article-id pub-id-type="doi">10.1177/0886260514567966</article-id><article-id pub-id-type="manuscript">NIHMS655943</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Prospective study of the mental health consequences of sexual violence among women living with HIV in rural Uganda</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Tsai</surname><given-names>Alexander C.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="corresp" rid="CR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Wolfe</surname><given-names>William R.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Kumbakumba</surname><given-names>Elias</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Kawuma</surname><given-names>Annet</given-names></name><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Hunt</surname><given-names>Peter W.</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Martin</surname><given-names>Jeffrey N.</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Bangsberg</surname><given-names>David R.</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Weiser</surname><given-names>Sheri D.</given-names></name><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A6">6</xref></contrib></contrib-group><aff id="A1"><label>1</label> Massachusetts General Hospital, Boston, USA</aff><aff id="A2"><label>2</label> Mbarara University of Science and Technology, Mbarara, Uganda</aff><aff id="A3"><label>3</label> Department of Psychiatry, University of California at San Francisco (UCSF), San Francisco, USA</aff><aff id="A4"><label>4</label> Positive Health Program, San Francisco General Hospital at UCSF, San Francisco, UCA</aff><aff id="A5"><label>5</label> UCSF Department of Epidemiology and Biostatistics, San Francisco, UCA</aff><aff id="A6"><label>6</label> Center for AIDS Prevention Studies, UCSF Department of Medicine, San Francisco, USA</aff><author-notes><corresp id="CR1"><label>*</label> Address correspondence to: Alexander C. Tsai, MD, PhD, Center for Global Health, Massachusetts General Hospital, 100 Cambridge Street, 15th floor, Boston, Massachusetts 02114 USA. <email>actsai@partners.org</email>. Tel.: (617) 724-1120. Fax (617) 724-1637.</corresp></author-notes><pub-date pub-type="nihms-submitted"><day>16</day><month>1</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>13</day><month>1</month><year>2015</year></pub-date><pub-date pub-type="ppub"><month>5</month><year>2016</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>5</month><year>2017</year></pub-date><volume>31</volume><issue>8</issue><fpage>1531</fpage><lpage>1553</lpage><pmc-comment>elocation-id from pubmed: 10.1177/0886260514567966</pmc-comment>
<abstract><p id="P1">The association between sexual violence and depression is well known, but the temporal aspects of the association have not been well established. We analyzed data from a cohort of 173 HIV-positive women in rural Uganda who were interviewed every 3 months for a median of 1.8 years of follow-up. The method of generalized estimating equations (GEE) was used to model the marginal expectation of depression symptom severity (Hopkins Symptom Checklist for Depression), mental health–related quality of life (MOS-HIV Mental Health Summary), and heavy drinking (Alcohol Use Disorders Identification Test) as a function of self-reported forced-sex victimization in the 3 months prior to interview. Estimates were adjusted for variables known to confound the association between victimization and mental health status. To assess any potential reciprocal relationships, we reversed the temporal ordering of the exposures and outcomes and refitted similar GEE models. In multivariable analyses, victimization was associated with greater depression symptom severity (<italic>b</italic> = 0.17; 95% CI = [0.02, 0.33]) and lower mental health–related quality of life (<italic>b</italic> = −5.65; 95% CI = [−9.34, −1.96]), as well as increased risks for probable depression (adjusted relative risk [ARR] = 1.58; 95% CI = [1.01, 2.49) and heavy drinking (ARR = 3.99; 95% CI = [1.84, 8.63]). We did not find strong evidence of a reciprocal relationship. Our findings suggest that forced sex is associated with adverse mental health outcomes among HIV-positive women in rural Uganda. Given the substantial mental health–related impacts of victimization, effective health sector responses are needed.</p></abstract><kwd-group><kwd>HIV</kwd><kwd>domestic violence</kwd><kwd>rape</kwd><kwd>Uganda</kwd><kwd>depressive disorder</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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