HIV-1 Prevention for HIV-1 Serodiscordant Couples
Identifieur interne : 001A13 ( Pmc/Corpus ); précédent : 001A12; suivant : 001A14HIV-1 Prevention for HIV-1 Serodiscordant Couples
Auteurs : Kathryn Curran ; Jared M. Baeten ; Thomas J. Coates ; Ann Kurth ; Nelly R. Mugo ; Connie CelumSource :
- Current HIV/AIDS reports [ 1548-3568 ] ; 2012.
Abstract
A substantial proportion of HIV-1-infected individuals in sub-Saharan Africa are in stable relationships with HIV-1-uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother to child transmission for HIV-1- infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.
Url:
DOI: 10.1007/s11904-012-0114-z
PubMed: 22415473
PubMed Central: 3570050
Links to Exploration step
PMC:3570050Le document en format XML
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<author><name sortKey="Curran, Kathryn" sort="Curran, Kathryn" uniqKey="Curran K" first="Kathryn" last="Curran">Kathryn Curran</name>
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<author><name sortKey="Baeten, Jared M" sort="Baeten, Jared M" uniqKey="Baeten J" first="Jared M." last="Baeten">Jared M. Baeten</name>
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<author><name sortKey="Coates, Thomas J" sort="Coates, Thomas J" uniqKey="Coates T" first="Thomas J." last="Coates">Thomas J. Coates</name>
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<author><name sortKey="Kurth, Ann" sort="Kurth, Ann" uniqKey="Kurth A" first="Ann" last="Kurth">Ann Kurth</name>
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<author><name sortKey="Mugo, Nelly R" sort="Mugo, Nelly R" uniqKey="Mugo N" first="Nelly R." last="Mugo">Nelly R. Mugo</name>
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<front><div type="abstract" xml:lang="en"><p id="P1">A substantial proportion of HIV-1-infected individuals in sub-Saharan Africa are in stable relationships with HIV-1-uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother to child transmission for HIV-1- infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.</p>
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<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101235661</journal-id>
<journal-id journal-id-type="pubmed-jr-id">32548</journal-id>
<journal-id journal-id-type="nlm-ta">Curr HIV/AIDS Rep</journal-id>
<journal-id journal-id-type="iso-abbrev">Curr HIV/AIDS Rep</journal-id>
<journal-title-group><journal-title>Current HIV/AIDS reports</journal-title>
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<issn pub-type="ppub">1548-3568</issn>
<issn pub-type="epub">1548-3576</issn>
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<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
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<title-group><article-title>HIV-1 Prevention for HIV-1 Serodiscordant Couples</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Curran</surname>
<given-names>Kathryn</given-names>
</name>
<degrees>MHS</degrees>
<aff id="A1">Department of Epidemiology, University of Washington, Seattle USA International Clinical Research Center, Department of Global Health University of Washington, Box 359927 325 Ninth Avenue; Seattle, WA 98104 T: 206-520-3811; F: 206-520-3831<email>kgcurran@uw.edu</email>
</aff>
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<contrib contrib-type="author"><name><surname>Baeten</surname>
<given-names>Jared M.</given-names>
</name>
<degrees>MD PhD</degrees>
<aff id="A2">Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, USA International Clinical Research Center, Department of Global Health University of Washington, Box 359927 325 Ninth Avenue; Seattle, WA 98104 T: 206-520-3808; F: 206-520-3831<email>jbaeten@uw.edu</email>
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<contrib contrib-type="author"><name><surname>Coates</surname>
<given-names>Thomas J.</given-names>
</name>
<degrees>PhD</degrees>
<aff id="A3">Division of Infectious Diseases and Program in Global Health, David Geffen School of Medicine, University of California, Los Angeles, USA 9911 West Pico Blvd., Suite 955; Los Angeles, CA 90035-2703 T: 310-557-3044; F: 310-557-3679<email>tcoates@mednet.ucla.edu</email>
</aff>
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<contrib contrib-type="author"><name><surname>Kurth</surname>
<given-names>Ann</given-names>
</name>
<degrees>CNM PhD</degrees>
<aff id="A4">New York University College of Nursing, New York, USA 1006 726 Broadway; New York, NY 10003 T: 212-998-5316; F: 212-995-3143<email>akurth@nyu.edu</email>
</aff>
</contrib>
<contrib contrib-type="author"><name><surname>Mugo</surname>
<given-names>Nelly R.</given-names>
</name>
<degrees>MBChB MMed MPH</degrees>
<aff id="A5">Department of Obstetrics and Gynecology, Kenyatta National Hospital/University of Nairobi, Nairobi, Kenya University of Nairobi Institute of Tropical and Infectious Diseases (UNITID) Kenyatta National Hospital, Ngong Rd, P.O. Box 19865-00202, Nairobi, Kenya T: 254-20-27376<email>rwamba@csrtkenya.org</email>
</aff>
</contrib>
<contrib contrib-type="author" corresp="yes"><name><surname>Celum</surname>
<given-names>Connie</given-names>
</name>
<degrees>MD MPH</degrees>
<aff id="A6">Departments of Global Health, Medicine, and Epidemiology, University of Washington, Seattle, USA International Clinical Research Center, Department of Global Health University of Washington, Box 359927 325 Ninth Avenue; Seattle, WA 98104 T: 206 520-382; F: 206-520-3831<email>ccelum@uw.edu</email>
</aff>
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<pub-date pub-type="nihms-submitted"><day>1</day>
<month>2</month>
<year>2013</year>
</pub-date>
<pub-date pub-type="ppub"><month>6</month>
<year>2012</year>
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<pub-date pub-type="pmc-release"><day>01</day>
<month>6</month>
<year>2013</year>
</pub-date>
<volume>9</volume>
<issue>2</issue>
<fpage>160</fpage>
<lpage>170</lpage>
<abstract><p id="P1">A substantial proportion of HIV-1-infected individuals in sub-Saharan Africa are in stable relationships with HIV-1-uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother to child transmission for HIV-1- infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.</p>
</abstract>
<kwd-group><kwd>HIV-1 serodiscordant couples</kwd>
<kwd>HIV-1 prevention</kwd>
<kwd>Africa</kwd>
<kwd>antiretroviral</kwd>
<kwd>ART</kwd>
<kwd>PrEP</kwd>
</kwd-group>
<funding-group><award-group><funding-source country="United States">National Institute of Nursing Research : NINR</funding-source>
<award-id>R21 NR012663 || NR</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source>
<award-id>R01 MH095507 || MH</award-id>
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</front>
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