Antenatal and perinatal predictors of infant mortality in rural Malawi
Identifieur interne : 001620 ( Pmc/Corpus ); précédent : 001619; suivant : 001621Antenatal and perinatal predictors of infant mortality in rural Malawi
Auteurs : M. Vaahtera ; T. Kulmala ; M. Ndekha ; A. Koivisto ; T. Cullinan ; M. Salin ; P. AshornSource :
- Archives of Disease in Childhood. Fetal and Neonatal Edition [ 1359-2998 ] ; 2000.
Abstract
Url:
DOI: 10.1136/fn.82.3.F200
PubMed: 10794786
PubMed Central: 1721093
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PMC:1721093Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Antenatal and perinatal predictors of infant mortality in rural
Malawi</title>
<author><name sortKey="Vaahtera, M" sort="Vaahtera, M" uniqKey="Vaahtera M" first="M." last="Vaahtera">M. Vaahtera</name>
</author>
<author><name sortKey="Kulmala, T" sort="Kulmala, T" uniqKey="Kulmala T" first="T." last="Kulmala">T. Kulmala</name>
</author>
<author><name sortKey="Ndekha, M" sort="Ndekha, M" uniqKey="Ndekha M" first="M." last="Ndekha">M. Ndekha</name>
</author>
<author><name sortKey="Koivisto, A" sort="Koivisto, A" uniqKey="Koivisto A" first="A." last="Koivisto">A. Koivisto</name>
</author>
<author><name sortKey="Cullinan, T" sort="Cullinan, T" uniqKey="Cullinan T" first="T." last="Cullinan">T. Cullinan</name>
</author>
<author><name sortKey="Salin, M" sort="Salin, M" uniqKey="Salin M" first="M." last="Salin">M. Salin</name>
</author>
<author><name sortKey="Ashorn, P" sort="Ashorn, P" uniqKey="Ashorn P" first="P." last="Ashorn">P. Ashorn</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">10794786</idno>
<idno type="pmc">1721093</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1721093</idno>
<idno type="RBID">PMC:1721093</idno>
<idno type="doi">10.1136/fn.82.3.F200</idno>
<date when="2000">2000</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antenatal and perinatal predictors of infant mortality in rural
Malawi</title>
<author><name sortKey="Vaahtera, M" sort="Vaahtera, M" uniqKey="Vaahtera M" first="M." last="Vaahtera">M. Vaahtera</name>
</author>
<author><name sortKey="Kulmala, T" sort="Kulmala, T" uniqKey="Kulmala T" first="T." last="Kulmala">T. Kulmala</name>
</author>
<author><name sortKey="Ndekha, M" sort="Ndekha, M" uniqKey="Ndekha M" first="M." last="Ndekha">M. Ndekha</name>
</author>
<author><name sortKey="Koivisto, A" sort="Koivisto, A" uniqKey="Koivisto A" first="A." last="Koivisto">A. Koivisto</name>
</author>
<author><name sortKey="Cullinan, T" sort="Cullinan, T" uniqKey="Cullinan T" first="T." last="Cullinan">T. Cullinan</name>
</author>
<author><name sortKey="Salin, M" sort="Salin, M" uniqKey="Salin M" first="M." last="Salin">M. Salin</name>
</author>
<author><name sortKey="Ashorn, P" sort="Ashorn, P" uniqKey="Ashorn P" first="P." last="Ashorn">P. Ashorn</name>
</author>
</analytic>
<series><title level="j">Archives of Disease in Childhood. Fetal and Neonatal Edition</title>
<idno type="ISSN">1359-2998</idno>
<idno type="eISSN">1468-2052</idno>
<imprint><date when="2000">2000</date>
</imprint>
</series>
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<front><div type="abstract" xml:lang="en"><p><italic>BACKGROUND</italic>
—The slow
pace in the reduction of infant mortality in sub-Saharan Africa has
partially been attributed to the epidemic of human immunodeficiency
virus (HIV) infection. To facilitate early interventions, antenatal and
perinatal predictors of 1st year mortality were identified in a rural
community in southern Malawi.
<italic>METHODS</italic>
—A cohort of
733 live born infants was studied prospectively from approximately 24 gestation weeks onwards. Univariate analysis was used to determine
relative risks for infant mortality after selected antenatal and
perinatal exposures. Multivariate modelling was used to control for
potential confounders.
<italic>FINDINGS</italic>
—The infant
mortality rate was 136 deaths/1000 live births. Among singleton
newborns, the strongest antenatal and perinatal predictors of mortality
were birth between May and July, maternal primiparity, birth before
38th gestation week, and maternal HIV infection. Theoretically,
exposure to these variables accounted for 22%, 22%, 17%, and 15% of
the population attributable risk for infant mortality, respectively.
<italic>INTERPRETATION</italic>
—The HIV
epidemic was an important but not the main determinant of infant
mortality. Interventions targetting the offspring of primiparous women
or infants born between May and July or prevention of prematurity would
all have considerable impact on infant survival.
</p>
</div>
</front>
</TEI>
<pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Arch Dis Child Fetal Neonatal Ed</journal-id>
<journal-title>Archives of Disease in Childhood. Fetal and Neonatal Edition</journal-title>
<issn pub-type="ppub">1359-2998</issn>
<issn pub-type="epub">1468-2052</issn>
<publisher><publisher-name>BMJ Group</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">10794786</article-id>
<article-id pub-id-type="pmc">1721093</article-id>
<article-id pub-id-type="doi">10.1136/fn.82.3.F200</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Original Articles</subject>
</subj-group>
</article-categories>
<title-group><article-title>Antenatal and perinatal predictors of infant mortality in rural
Malawi</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Vaahtera</surname>
<given-names>M.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Kulmala</surname>
<given-names>T.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Ndekha</surname>
<given-names>M.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Koivisto</surname>
<given-names>A.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Cullinan</surname>
<given-names>T.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Salin</surname>
<given-names>M.</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Ashorn</surname>
<given-names>P.</given-names>
</name>
</contrib>
</contrib-group>
<pub-date pub-type="ppub"><month>5</month>
<year>2000</year>
</pub-date>
<volume>82</volume>
<issue>3</issue>
<fpage>F200</fpage>
<lpage>F204</lpage>
<self-uri xlink:role="pdf" xlink:type="simple" xlink:href="http://fn.bmj.com/cgi/reprint/82/3/F200.pdf"></self-uri>
<self-uri xlink:role="abstract" xlink:type="simple" xlink:href="http://fn.bmj.com/cgi/content/abstract/82/3/F200"></self-uri>
<self-uri xlink:role="fulltext" xlink:type="simple" xlink:href="http://fn.bmj.com/cgi/content/full/82/3/F200"></self-uri>
<abstract><p><italic>BACKGROUND</italic>
—The slow
pace in the reduction of infant mortality in sub-Saharan Africa has
partially been attributed to the epidemic of human immunodeficiency
virus (HIV) infection. To facilitate early interventions, antenatal and
perinatal predictors of 1st year mortality were identified in a rural
community in southern Malawi.
<italic>METHODS</italic>
—A cohort of
733 live born infants was studied prospectively from approximately 24 gestation weeks onwards. Univariate analysis was used to determine
relative risks for infant mortality after selected antenatal and
perinatal exposures. Multivariate modelling was used to control for
potential confounders.
<italic>FINDINGS</italic>
—The infant
mortality rate was 136 deaths/1000 live births. Among singleton
newborns, the strongest antenatal and perinatal predictors of mortality
were birth between May and July, maternal primiparity, birth before
38th gestation week, and maternal HIV infection. Theoretically,
exposure to these variables accounted for 22%, 22%, 17%, and 15% of
the population attributable risk for infant mortality, respectively.
<italic>INTERPRETATION</italic>
—The HIV
epidemic was an important but not the main determinant of infant
mortality. Interventions targetting the offspring of primiparous women
or infants born between May and July or prevention of prematurity would
all have considerable impact on infant survival.
</p>
</abstract>
</article-meta>
</front>
</pmc>
</record>
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