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<TEI>
<teiHeader>
<fileDesc>
<titleStmt>
<title xml:lang="en">Psychological distress and adherence to highly active anti-retroviral therapy (HAART) in Uganda: A pilot study</title>
<author>
<name sortKey="Nakimuli Mpungu, Etheldreda" sort="Nakimuli Mpungu, Etheldreda" uniqKey="Nakimuli Mpungu E" first="Etheldreda" last="Nakimuli-Mpungu">Etheldreda Nakimuli-Mpungu</name>
</author>
<author>
<name sortKey="Mutamba, Brian" sort="Mutamba, Brian" uniqKey="Mutamba B" first="Brian" last="Mutamba">Brian Mutamba</name>
</author>
<author>
<name sortKey="Othengo, Makanga" sort="Othengo, Makanga" uniqKey="Othengo M" first="Makanga" last="Othengo">Makanga Othengo</name>
</author>
<author>
<name sortKey="Musisi, Seggane" sort="Musisi, Seggane" uniqKey="Musisi S" first="Seggane" last="Musisi">Seggane Musisi</name>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PMC</idno>
<idno type="pmid">20589156</idno>
<idno type="pmc">2890994</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890994</idno>
<idno type="RBID">PMC:2890994</idno>
<date when="2009">2009</date>
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<analytic>
<title xml:lang="en" level="a" type="main">Psychological distress and adherence to highly active anti-retroviral therapy (HAART) in Uganda: A pilot study</title>
<author>
<name sortKey="Nakimuli Mpungu, Etheldreda" sort="Nakimuli Mpungu, Etheldreda" uniqKey="Nakimuli Mpungu E" first="Etheldreda" last="Nakimuli-Mpungu">Etheldreda Nakimuli-Mpungu</name>
</author>
<author>
<name sortKey="Mutamba, Brian" sort="Mutamba, Brian" uniqKey="Mutamba B" first="Brian" last="Mutamba">Brian Mutamba</name>
</author>
<author>
<name sortKey="Othengo, Makanga" sort="Othengo, Makanga" uniqKey="Othengo M" first="Makanga" last="Othengo">Makanga Othengo</name>
</author>
<author>
<name sortKey="Musisi, Seggane" sort="Musisi, Seggane" uniqKey="Musisi S" first="Seggane" last="Musisi">Seggane Musisi</name>
</author>
</analytic>
<series>
<title level="j">African Health Sciences</title>
<idno type="ISSN">1680-6905</idno>
<idno type="eISSN">1729-0503</idno>
<imprint>
<date when="2009">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<sec>
<title>Background</title>
<p>Mental health related risk factors for non-adherence to highly active anti-retroviral therapy (HAART) have not been investigated in Uganda and yet adherence is critical to the success of the current scale up in the provision of HAART to HIV positive individuals in rural areas of Uganda.</p>
</sec>
<sec>
<title>Objective</title>
<p>To determine whether psychological distress is a risk factor for non-adherence to HAART among HIV positive individuals.</p>
</sec>
<sec sec-type="methods">
<title>Method</title>
<p>One hundred twenty-two HIV positive adult individuals receiving care from an Urban HIV clinic were enrolled in the study. Participants were screened for psychological distress with the Self Report Questionnaire (SRQ-20). Adherence was assessed using the self report method. Multivariate logistic regression analysis was used to determine whether psychological distress is a risk factor for non-adherence to HAART adjusting for various socio-demographic and clinical factors.</p>
</sec>
<sec sec-type="results">
<title>Results</title>
<p>Psychological distress and living in isolation were significantly associated with non-adherence to HAART after adjusting for other demographic and clinical variables [OR=3.66, 95%CI (1.39 – 9.78) and OR=9.80, 95%CI (2.27 – 18.70)] respectively. Among HIV positive individuals who were receiving additional treatment for a mental disorder, psychological distress was not significantly associated with non-adherence to HAART [OR= 1.25, 95%CI (0.30 – 5.20)]</p>
</sec>
<sec sec-type="conclusions">
<title>Conclusion</title>
<p>Regular screening and management of psychological distress may prevent further complications in HIV positive individuals in Uganda.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article">
<pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Afr Health Sci</journal-id>
<journal-id journal-id-type="iso-abbrev">Afr Health Sci</journal-id>
<journal-title-group>
<journal-title>African Health Sciences</journal-title>
</journal-title-group>
<issn pub-type="ppub">1680-6905</issn>
<issn pub-type="epub">1729-0503</issn>
<publisher>
<publisher-name>Makerere Medical School</publisher-name>
<publisher-loc>Kampala, Uganda</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">20589156</article-id>
<article-id pub-id-type="pmc">2890994</article-id>
<article-id pub-id-type="publisher-id">jAFHS.v9.i1.pgS2</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Psychological distress and adherence to highly active anti-retroviral therapy (HAART) in Uganda: A pilot study</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Nakimuli-Mpungu</surname>
<given-names>Etheldreda</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Mutamba</surname>
<given-names>Brian</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Othengo</surname>
<given-names>Makanga</given-names>
</name>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Musisi</surname>
<given-names>Seggane</given-names>
</name>
</contrib>
</contrib-group>
<aff>Makerere Univerity College of Health Sciences, School of Medicine, Department of Psychiatry, P. O. Box 7072 Kampala, Uganda</aff>
<author-notes>
<corresp>
<bold>Corresponding Author:</bold>
Etheldreda Nakimuli-Mpungu Johns Hopkins Bloomberg School of Public Health Mental health Department 624 N. Broadway, Hampton House, Rm 784, Baltimore, MD 21205 Email:
<email>enakimul@jhsph.edu</email>
,
<email>e.nakimuli-mpungu07@fulbrightmail.org</email>
Tel: +1 443 839 4012 Fax +1 410 614 74 69</corresp>
</author-notes>
<pub-date pub-type="ppub">
<day>1</day>
<month>8</month>
<year>2009</year>
</pub-date>
<volume>9</volume>
<issue>Suppl 1</issue>
<fpage>S2</fpage>
<lpage>S7</lpage>
<permissions>
<copyright-statement>Copyright © Makerere Medical School, Uganda 2009</copyright-statement>
<copyright-year>2009</copyright-year>
</permissions>
<abstract abstract-type="executive-summary">
<sec>
<title>Background</title>
<p>Mental health related risk factors for non-adherence to highly active anti-retroviral therapy (HAART) have not been investigated in Uganda and yet adherence is critical to the success of the current scale up in the provision of HAART to HIV positive individuals in rural areas of Uganda.</p>
</sec>
<sec>
<title>Objective</title>
<p>To determine whether psychological distress is a risk factor for non-adherence to HAART among HIV positive individuals.</p>
</sec>
<sec sec-type="methods">
<title>Method</title>
<p>One hundred twenty-two HIV positive adult individuals receiving care from an Urban HIV clinic were enrolled in the study. Participants were screened for psychological distress with the Self Report Questionnaire (SRQ-20). Adherence was assessed using the self report method. Multivariate logistic regression analysis was used to determine whether psychological distress is a risk factor for non-adherence to HAART adjusting for various socio-demographic and clinical factors.</p>
</sec>
<sec sec-type="results">
<title>Results</title>
<p>Psychological distress and living in isolation were significantly associated with non-adherence to HAART after adjusting for other demographic and clinical variables [OR=3.66, 95%CI (1.39 – 9.78) and OR=9.80, 95%CI (2.27 – 18.70)] respectively. Among HIV positive individuals who were receiving additional treatment for a mental disorder, psychological distress was not significantly associated with non-adherence to HAART [OR= 1.25, 95%CI (0.30 – 5.20)]</p>
</sec>
<sec sec-type="conclusions">
<title>Conclusion</title>
<p>Regular screening and management of psychological distress may prevent further complications in HIV positive individuals in Uganda.</p>
</sec>
</abstract>
</article-meta>
</front>
</pmc>
</record>

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