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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Millennium development goal 6 and HIV infection in Zambia: what can we learn from successive household surveys?</title>
<author><name sortKey="Kandala, Ngianga Bakwin" sort="Kandala, Ngianga Bakwin" uniqKey="Kandala N" first="Ngianga-Bakwin" last="Kandala">Ngianga-Bakwin Kandala</name>
</author>
<author><name sortKey="Brodish, Paul" sort="Brodish, Paul" uniqKey="Brodish P" first="Paul" last="Brodish">Paul Brodish</name>
</author>
<author><name sortKey="Buckner, Bates" sort="Buckner, Bates" uniqKey="Buckner B" first="Bates" last="Buckner">Bates Buckner</name>
</author>
<author><name sortKey="Foster, Susan" sort="Foster, Susan" uniqKey="Foster S" first="Susan" last="Foster">Susan Foster</name>
</author>
<author><name sortKey="Madise, Nyovani" sort="Madise, Nyovani" uniqKey="Madise N" first="Nyovani" last="Madise">Nyovani Madise</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21099671</idno>
<idno type="pmc">3145216</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145216</idno>
<idno type="RBID">PMC:3145216</idno>
<idno type="doi">10.1097/QAD.0b013e328340fe0f</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">001201</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001201</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Millennium development goal 6 and HIV infection in Zambia: what can we learn from successive household surveys?</title>
<author><name sortKey="Kandala, Ngianga Bakwin" sort="Kandala, Ngianga Bakwin" uniqKey="Kandala N" first="Ngianga-Bakwin" last="Kandala">Ngianga-Bakwin Kandala</name>
</author>
<author><name sortKey="Brodish, Paul" sort="Brodish, Paul" uniqKey="Brodish P" first="Paul" last="Brodish">Paul Brodish</name>
</author>
<author><name sortKey="Buckner, Bates" sort="Buckner, Bates" uniqKey="Buckner B" first="Bates" last="Buckner">Bates Buckner</name>
</author>
<author><name sortKey="Foster, Susan" sort="Foster, Susan" uniqKey="Foster S" first="Susan" last="Foster">Susan Foster</name>
</author>
<author><name sortKey="Madise, Nyovani" sort="Madise, Nyovani" uniqKey="Madise N" first="Nyovani" last="Madise">Nyovani Madise</name>
</author>
</analytic>
<series><title level="j">AIDS (London, England)</title>
<idno type="ISSN">0269-9370</idno>
<idno type="eISSN">1473-5571</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Geographic location represents an ecological measure of HIV status and is a strong predictor of HIV prevalence. Given the complex nature of location effects, there is limited understanding of their impact on policies to reduce HIV prevalence.</p>
</sec>
<sec sec-type="methods" id="S2"><title>Methods</title>
<p id="P2">Participants were 3,949 and 10,874 respondents from two consecutive Zambia Demographic and Health Surveys from 2001/7 (mean age for men and women: 30.3 and 27.7 years, HIV prevalence 14.3% in 2001/2002; 30.3 and 28.0 years, HIV prevalence of 14.7% in 2007). A Bayesian geo-additive mixed model based on Markov Chain Monte Carlo techniques was used to map the change in the spatial distribution of HIV/AIDS prevalence at the provincial level during the six-year period, accounting for important risk factors.</p>
</sec>
<sec id="S3"><title>Findings</title>
<p id="P3">Overall HIV/AIDS prevalence changed little over the 6-year period, but the mapping of residual spatial effects at the provincial level suggested different regional patterns. A pronounced change in odds ratios in Lusaka and Copperbelt provinces in 2001/2 and in Lusaka and Central provinces in 2007 were observed following adjustment for spatial autocorrelation. Western province went from a lower prevalence area in 2001 (13.4%) to a higher prevalence area in 2007 (17.3%). Southern province went from the highest prevalence area in 2001 (17.3%) to a lower prevalence area in 2007 (15.9%).</p>
</sec>
<sec id="S4"><title>Interpretation</title>
<p id="P4">Findings from two consecutive surveys corroborate the Zambian government’s effort to achieve MDG 6. The novel finding of increased prevalence in Western province warrants further investigation. Spatially-adjusted provincial-level HIV/AIDS prevalence maps are a useful tool for informing policies to achieve MDG 6 in Zambia.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article" xml:lang="en"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8710219</journal-id>
<journal-id journal-id-type="pubmed-jr-id">1493</journal-id>
<journal-id journal-id-type="nlm-ta">AIDS</journal-id>
<journal-title-group><journal-title>AIDS (London, England)</journal-title>
</journal-title-group>
<issn pub-type="ppub">0269-9370</issn>
<issn pub-type="epub">1473-5571</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">21099671</article-id>
<article-id pub-id-type="pmc">3145216</article-id>
<article-id pub-id-type="doi">10.1097/QAD.0b013e328340fe0f</article-id>
<article-id pub-id-type="manuscript">NIHMS308292</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>Millennium development goal 6 and HIV infection in Zambia: what can we learn from successive household surveys?</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Kandala</surname>
<given-names>Ngianga-Bakwin</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Brodish</surname>
<given-names>Paul</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Buckner</surname>
<given-names>Bates</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Foster</surname>
<given-names>Susan</given-names>
</name>
</contrib>
<contrib contrib-type="author"><name><surname>Madise</surname>
<given-names>Nyovani</given-names>
</name>
</contrib>
</contrib-group>
<pub-date pub-type="nihms-submitted"><day>14</day>
<month>7</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="ppub"><day>2</day>
<month>1</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>28</day>
<month>7</month>
<year>2011</year>
</pub-date>
<volume>25</volume>
<issue>1</issue>
<fpage>95</fpage>
<lpage>106</lpage>
<abstract><sec id="S1"><title>Background</title>
<p id="P1">Geographic location represents an ecological measure of HIV status and is a strong predictor of HIV prevalence. Given the complex nature of location effects, there is limited understanding of their impact on policies to reduce HIV prevalence.</p>
</sec>
<sec sec-type="methods" id="S2"><title>Methods</title>
<p id="P2">Participants were 3,949 and 10,874 respondents from two consecutive Zambia Demographic and Health Surveys from 2001/7 (mean age for men and women: 30.3 and 27.7 years, HIV prevalence 14.3% in 2001/2002; 30.3 and 28.0 years, HIV prevalence of 14.7% in 2007). A Bayesian geo-additive mixed model based on Markov Chain Monte Carlo techniques was used to map the change in the spatial distribution of HIV/AIDS prevalence at the provincial level during the six-year period, accounting for important risk factors.</p>
</sec>
<sec id="S3"><title>Findings</title>
<p id="P3">Overall HIV/AIDS prevalence changed little over the 6-year period, but the mapping of residual spatial effects at the provincial level suggested different regional patterns. A pronounced change in odds ratios in Lusaka and Copperbelt provinces in 2001/2 and in Lusaka and Central provinces in 2007 were observed following adjustment for spatial autocorrelation. Western province went from a lower prevalence area in 2001 (13.4%) to a higher prevalence area in 2007 (17.3%). Southern province went from the highest prevalence area in 2001 (17.3%) to a lower prevalence area in 2007 (15.9%).</p>
</sec>
<sec id="S4"><title>Interpretation</title>
<p id="P4">Findings from two consecutive surveys corroborate the Zambian government’s effort to achieve MDG 6. The novel finding of increased prevalence in Western province warrants further investigation. Spatially-adjusted provincial-level HIV/AIDS prevalence maps are a useful tool for informing policies to achieve MDG 6 in Zambia.</p>
</sec>
</abstract>
<kwd-group><kwd>MDG 6</kwd>
<kwd>HIV prevalence</kwd>
<kwd>geographic location</kwd>
<kwd>spatial autocorrelation</kwd>
</kwd-group>
<funding-group><award-group><funding-source country="United States">National Institute of Child Health & Human Development : NICHD</funding-source>
<award-id>R24 HD050924-05 || HD</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
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