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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The mental health impact of AIDS-related mortality in South Africa: a national study</title>
<author><name sortKey="Myer, L" sort="Myer, L" uniqKey="Myer L" first="L" last="Myer">L. Myer</name>
<affiliation><nlm:aff id="A1">School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A2">Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Seedat, S" sort="Seedat, S" uniqKey="Seedat S" first="S" last="Seedat">S. Seedat</name>
<affiliation><nlm:aff id="A3">MRC Stress and Anxiety Disorders Unit, Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stein, D J" sort="Stein, D J" uniqKey="Stein D" first="D J" last="Stein">D J Stein</name>
<affiliation><nlm:aff id="A3">MRC Stress and Anxiety Disorders Unit, Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Moomal, H" sort="Moomal, H" uniqKey="Moomal H" first="H" last="Moomal">H. Moomal</name>
<affiliation><nlm:aff id="A5">University of the Witwatersrand, Johannesburg, South Africa</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Williams, D R" sort="Williams, D R" uniqKey="Williams D" first="D R" last="Williams">D R Williams</name>
<affiliation><nlm:aff id="A6">Department of Society, Human Development and Health, Harvard School of Public Health, Boston, USA</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">19074926</idno>
<idno type="pmc">3203694</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203694</idno>
<idno type="RBID">PMC:3203694</idno>
<idno type="doi">10.1136/jech.2008.080861</idno>
<date when="2008">2008</date>
<idno type="wicri:Area/Pmc/Corpus">001190</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001190</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The mental health impact of AIDS-related mortality in South Africa: a national study</title>
<author><name sortKey="Myer, L" sort="Myer, L" uniqKey="Myer L" first="L" last="Myer">L. Myer</name>
<affiliation><nlm:aff id="A1">School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A2">Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Seedat, S" sort="Seedat, S" uniqKey="Seedat S" first="S" last="Seedat">S. Seedat</name>
<affiliation><nlm:aff id="A3">MRC Stress and Anxiety Disorders Unit, Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Stein, D J" sort="Stein, D J" uniqKey="Stein D" first="D J" last="Stein">D J Stein</name>
<affiliation><nlm:aff id="A3">MRC Stress and Anxiety Disorders Unit, Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa</nlm:aff>
</affiliation>
<affiliation><nlm:aff id="A4">Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Moomal, H" sort="Moomal, H" uniqKey="Moomal H" first="H" last="Moomal">H. Moomal</name>
<affiliation><nlm:aff id="A5">University of the Witwatersrand, Johannesburg, South Africa</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Williams, D R" sort="Williams, D R" uniqKey="Williams D" first="D R" last="Williams">D R Williams</name>
<affiliation><nlm:aff id="A6">Department of Society, Human Development and Health, Harvard School of Public Health, Boston, USA</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Journal of epidemiology and community health</title>
<idno type="ISSN">0143-005X</idno>
<idno type="eISSN">1470-2738</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec id="S1"><title>Background</title>
<p id="P1">Few data exist on how the HIV/AIDS epidemic may influence population mental health. The associations were examined between knowing someone who died of HIV/AIDS and common mental disorders among South African adults.</p>
</sec>
<sec sec-type="methods" id="S2"><title>Methods</title>
<p id="P2">Between 2002 and 2004, a nationally representative sample of 4351 adults were interviewed about personally knowing someone who died of HIV/AIDS, and the World Health Organization Composite International Diagnostic Interview was used to generate psychiatric diagnoses for depression, anxiety and substance abuse disorders during the preceding 12 months based on the <italic>Diagnostic and Statistical Manual</italic>
, 4th edition (DSM-IV).</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Overall, 42.2% of the sample knew someone who died of HIV/AIDS, and 16.5% met the criteria for at least one DSM-IV diagnosis. Individuals who knew someone who died of HIV/AIDS were significantly more likely to have any DSM-IV defined disorder, including any depressive, anxiety or substance-related disorder (p<0.001 for all associations). In multivariate models adjusted for participant demographic characteristics, life events and socioeconomic status, individual disorders significantly associated with knowing someone who died of HIV/AIDS included generalised anxiety disorder, social phobia and alcohol/drug dependence or abuse. Based on these results, it is estimated that up to 15% of 12-month DSM-IV disorders in the South African adult population may be related to knowing someone who died of HIV/AIDS.</p>
</sec>
<sec id="S4"><title>Conclusion</title>
<p id="P4">These novel data suggest that AIDS-related mortality may contribute substantially to the burden of mental disorders in settings of high HIV prevalence. While this finding requires further investigation, these data suggest the need to strengthen mental health services in communities where HIV/AIDS is prevalent.</p>
</sec>
</div>
</front>
</TEI>
<pmc article-type="research-article" xml:lang="en"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">7909766</journal-id>
<journal-id journal-id-type="pubmed-jr-id">4717</journal-id>
<journal-id journal-id-type="nlm-ta">J Epidemiol Community Health</journal-id>
<journal-title-group><journal-title>Journal of epidemiology and community health</journal-title>
</journal-title-group>
<issn pub-type="ppub">0143-005X</issn>
<issn pub-type="epub">1470-2738</issn>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">19074926</article-id>
<article-id pub-id-type="pmc">3203694</article-id>
<article-id pub-id-type="doi">10.1136/jech.2008.080861</article-id>
<article-id pub-id-type="manuscript">NIHMS327466</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Article</subject>
</subj-group>
</article-categories>
<title-group><article-title>The mental health impact of AIDS-related mortality in South Africa: a national study</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Myer</surname>
<given-names>L</given-names>
</name>
<xref rid="A1" ref-type="aff">1</xref>
<xref rid="A2" ref-type="aff">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Seedat</surname>
<given-names>S</given-names>
</name>
<xref rid="A3" ref-type="aff">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Stein</surname>
<given-names>D J</given-names>
</name>
<xref rid="A3" ref-type="aff">3</xref>
<xref rid="A4" ref-type="aff">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Moomal</surname>
<given-names>H</given-names>
</name>
<xref rid="A5" ref-type="aff">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Williams</surname>
<given-names>D R</given-names>
</name>
<xref rid="A6" ref-type="aff">6</xref>
</contrib>
</contrib-group>
<aff id="A1"><label>1</label>
School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa</aff>
<aff id="A2"><label>2</label>
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA</aff>
<aff id="A3"><label>3</label>
MRC Stress and Anxiety Disorders Unit, Department of Psychiatry, University of Stellenbosch, Tygerberg, South Africa</aff>
<aff id="A4"><label>4</label>
Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa</aff>
<aff id="A5"><label>5</label>
University of the Witwatersrand, Johannesburg, South Africa</aff>
<aff id="A6"><label>6</label>
Department of Society, Human Development and Health, Harvard School of Public Health, Boston, USA</aff>
<author-notes><corresp id="FN1">Correspondence to: Professor L Myer, School of Public Health and Family Medicine, University of Cape Town, Anzio Road, Observatory 7925, Cape Town, South Africa; <email>landon.myer@uct.ac.za</email>
</corresp>
</author-notes>
<pub-date pub-type="nihms-submitted"><day>3</day>
<month>10</month>
<year>2011</year>
</pub-date>
<pub-date pub-type="epub"><day>15</day>
<month>12</month>
<year>2008</year>
</pub-date>
<pub-date pub-type="ppub"><month>4</month>
<year>2009</year>
</pub-date>
<pub-date pub-type="pmc-release"><day>28</day>
<month>10</month>
<year>2011</year>
</pub-date>
<volume>63</volume>
<issue>4</issue>
<fpage>293</fpage>
<lpage>298</lpage>
<abstract><sec id="S1"><title>Background</title>
<p id="P1">Few data exist on how the HIV/AIDS epidemic may influence population mental health. The associations were examined between knowing someone who died of HIV/AIDS and common mental disorders among South African adults.</p>
</sec>
<sec sec-type="methods" id="S2"><title>Methods</title>
<p id="P2">Between 2002 and 2004, a nationally representative sample of 4351 adults were interviewed about personally knowing someone who died of HIV/AIDS, and the World Health Organization Composite International Diagnostic Interview was used to generate psychiatric diagnoses for depression, anxiety and substance abuse disorders during the preceding 12 months based on the <italic>Diagnostic and Statistical Manual</italic>
, 4th edition (DSM-IV).</p>
</sec>
<sec id="S3"><title>Results</title>
<p id="P3">Overall, 42.2% of the sample knew someone who died of HIV/AIDS, and 16.5% met the criteria for at least one DSM-IV diagnosis. Individuals who knew someone who died of HIV/AIDS were significantly more likely to have any DSM-IV defined disorder, including any depressive, anxiety or substance-related disorder (p<0.001 for all associations). In multivariate models adjusted for participant demographic characteristics, life events and socioeconomic status, individual disorders significantly associated with knowing someone who died of HIV/AIDS included generalised anxiety disorder, social phobia and alcohol/drug dependence or abuse. Based on these results, it is estimated that up to 15% of 12-month DSM-IV disorders in the South African adult population may be related to knowing someone who died of HIV/AIDS.</p>
</sec>
<sec id="S4"><title>Conclusion</title>
<p id="P4">These novel data suggest that AIDS-related mortality may contribute substantially to the burden of mental disorders in settings of high HIV prevalence. While this finding requires further investigation, these data suggest the need to strengthen mental health services in communities where HIV/AIDS is prevalent.</p>
</sec>
</abstract>
<funding-group><award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source>
<award-id>R13 MH066849-05 || MH</award-id>
</award-group>
<award-group><funding-source country="United States">Fogarty International Center : FIC</funding-source>
<award-id>R03 TW006481-03 || TW</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source>
<award-id>R01 MH070884-05 || MH</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source>
<award-id>R01 MH069864-04 || MH</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute of Mental Health : NIMH</funding-source>
<award-id>R01 MH059575-09 || MH</award-id>
</award-group>
<award-group><funding-source country="United States">National Institute on Drug Abuse : NIDA</funding-source>
<award-id>R01 DA016558-06 || DA</award-id>
</award-group>
</funding-group>
</article-meta>
</front>
</pmc>
</record>
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