The Future of HIV Prevention: STI control and Circumcision Interventions
Identifieur interne : 001083 ( Pmc/Corpus ); précédent : 001082; suivant : 001084The Future of HIV Prevention: STI control and Circumcision Interventions
Auteurs : Vikrant V. Sahasrabuddhe ; Sten H. VermundSource :
- Infectious disease clinics of North America [ 0891-5520 ] ; 2007.
Abstract
Prevention and control of sexually transmitted infections (STIs) has proven effective in reducing HIV infection when treatment is available promptly for symptomatic persons in conditions of an emerging infection. Biologically, it is assumed that reduced genital tract inflammation reduces infectiousness for HIV as well as reducing susceptibility in HIV-uninfected persons. Other strategies may not work however, such as periodic mass chemotherapy for STIs. Male circumcision has been demonstrated effective in reducing risk for HIV infection in three separate trials from South Africa, Kenya, and Uganda. Global expansion of STI treatment and male circumcision programs is a vital tool for control of HIV infection; current research priorities are presented.
Url:
DOI: 10.1016/j.idc.2007.03.005
PubMed: 17502238
PubMed Central: 2700301
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Future of HIV Prevention: STI control and Circumcision Interventions</title><author><name sortKey="Sahasrabuddhe, Vikrant V" sort="Sahasrabuddhe, Vikrant V" uniqKey="Sahasrabuddhe V" first="Vikrant V." last="Sahasrabuddhe">Vikrant V. Sahasrabuddhe</name><affiliation><nlm:aff id="A1"> Research Assistant Professor, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN</nlm:aff></affiliation></author><author><name sortKey="Vermund, Sten H" sort="Vermund, Sten H" uniqKey="Vermund S" first="Sten H." last="Vermund">Sten H. Vermund</name><affiliation><nlm:aff id="A2"> Professor, Department of Pediatrics; Director, Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TN</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">17502238</idno><idno type="pmc">2700301</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700301</idno><idno type="RBID">PMC:2700301</idno><idno type="doi">10.1016/j.idc.2007.03.005</idno><date when="2007">2007</date><idno type="wicri:Area/Pmc/Corpus">001083</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001083</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Future of HIV Prevention: STI control and Circumcision Interventions</title><author><name sortKey="Sahasrabuddhe, Vikrant V" sort="Sahasrabuddhe, Vikrant V" uniqKey="Sahasrabuddhe V" first="Vikrant V." last="Sahasrabuddhe">Vikrant V. Sahasrabuddhe</name><affiliation><nlm:aff id="A1"> Research Assistant Professor, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN</nlm:aff></affiliation></author><author><name sortKey="Vermund, Sten H" sort="Vermund, Sten H" uniqKey="Vermund S" first="Sten H." last="Vermund">Sten H. Vermund</name><affiliation><nlm:aff id="A2"> Professor, Department of Pediatrics; Director, Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TN</nlm:aff></affiliation></author></analytic><series><title level="j">Infectious disease clinics of North America</title><idno type="ISSN">0891-5520</idno><idno type="eISSN">1557-9824</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Synopsis</title><p id="P3">Prevention and control of sexually transmitted infections (STIs) has proven effective in reducing HIV infection when treatment is available promptly for symptomatic persons in conditions of an emerging infection. Biologically, it is assumed that reduced genital tract inflammation reduces infectiousness for HIV as well as reducing susceptibility in HIV-uninfected persons. Other strategies may not work however, such as periodic mass chemotherapy for STIs. Male circumcision has been demonstrated effective in reducing risk for HIV infection in three separate trials from South Africa, Kenya, and Uganda. Global expansion of STI treatment and male circumcision programs is a vital tool for control of HIV infection; current research priorities are presented.</p></div></front></TEI><pmc article-type="research-article" xml:lang="EN"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8804508</journal-id><journal-id journal-id-type="pubmed-jr-id">4799</journal-id><journal-id journal-id-type="nlm-ta">Infect Dis Clin North Am</journal-id><journal-title>Infectious disease clinics of North America</journal-title><issn pub-type="ppub">0891-5520</issn><issn pub-type="epub">1557-9824</issn></journal-meta><article-meta><article-id pub-id-type="pmid">17502238</article-id><article-id pub-id-type="pmc">2700301</article-id><article-id pub-id-type="doi">10.1016/j.idc.2007.03.005</article-id><article-id pub-id-type="manuscript">NIHMS25330</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>The Future of HIV Prevention: STI control and Circumcision Interventions</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Sahasrabuddhe</surname><given-names>Vikrant V.</given-names></name><degrees>MBBS, DrPH</degrees><xref rid="A1" ref-type="aff">a</xref></contrib><contrib contrib-type="author" corresp="yes"><name><surname>Vermund</surname><given-names>Sten H.</given-names></name><degrees>MD, PhD</degrees><xref rid="A2" ref-type="aff">b</xref></contrib></contrib-group><aff id="A1"><label>a</label> Research Assistant Professor, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN</aff><aff id="A2"><label>b</label> Professor, Department of Pediatrics; Director, Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TN</aff><author-notes><fn id="FN1"><p>Contact information for both authors: Institute for Global Health, Vanderbilt University [319 Light Hall], Nashville, TN 37232-0242, Tel: 615-322-9374, Fax: 615-322-9400, Emails: <email>v.sahas@vanderbilt.edu</email>, <email>sten.vermund@vanderbilt.edu</email></p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>23</day><month>4</month><year>2009</year></pub-date><pub-date pub-type="ppub"><month>3</month><year>2007</year></pub-date><pub-date pub-type="pmc-release"><day>23</day><month>6</month><year>2009</year></pub-date><volume>21</volume><issue>1</issue><fpage>241</fpage><lpage>xi</lpage><abstract><title>Synopsis</title><p id="P3">Prevention and control of sexually transmitted infections (STIs) has proven effective in reducing HIV infection when treatment is available promptly for symptomatic persons in conditions of an emerging infection. Biologically, it is assumed that reduced genital tract inflammation reduces infectiousness for HIV as well as reducing susceptibility in HIV-uninfected persons. Other strategies may not work however, such as periodic mass chemotherapy for STIs. Male circumcision has been demonstrated effective in reducing risk for HIV infection in three separate trials from South Africa, Kenya, and Uganda. Global expansion of STI treatment and male circumcision programs is a vital tool for control of HIV infection; current research priorities are presented.</p></abstract><kwd-group><kwd>HIV</kwd><kwd>AIDS</kwd><kwd>prevention</kwd><kwd>sexually transmitted infections</kwd><kwd>circumcision</kwd><kwd>public health</kwd></kwd-group><contract-num rid="AI1">U01 AI068619-01</contract-num><contract-num rid="TW1">D43 TW001443-01S2</contract-num><contract-num rid="TW1">D43 TW001035-08</contract-num><contract-num rid="TW1">D43 TW000010-19</contract-num><contract-sponsor id="AI1">National Institute of Allergy and Infectious Diseases Extramural Activities : NIAID</contract-sponsor><contract-sponsor id="TW1">Fogarty International Center : FIC</contract-sponsor></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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