Getting the basic rights – the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework
Identifieur interne : 000247 ( Pmc/Corpus ); précédent : 000246; suivant : 000248Getting the basic rights – the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework
Auteurs : Oona M R. Campbell ; Lenka Benova ; Giorgia Gon ; Kaosar Afsana ; Oliver CummingSource :
- Tropical Medicine & International Health [ 1360-2276 ] ; 2014.
Abstract
To explore linkages between water, sanitation and hygiene (WASH) and maternal and perinatal health via a conceptual approach and a scoping review.
We developed a conceptual framework iteratively, amalgamating three literature-based lenses. We then searched literature and identified risk factors potentially linked to maternal and perinatal health. We conducted a systematic scoping review for all chemical and biological WASH risk factors identified using text and MeSH terms, limiting results to systematic reviews or meta-analyses. The remaining 10 complex behavioural associations were not reviewed systematically.
The main ways poor WASH could lead to adverse outcomes are via two non-exclusive categories: 1. ‘In-water’ associations: (a) Inorganic contaminants, and (b) ‘water-system’ related infections, (c) ‘water-based’ infections, and (d) ‘water borne’ infections. 2. ‘Behaviour’ associations: (e) Behaviours leading to water-washed infections, (f) Water-related insect-vector infections, and (g-i) Behaviours leading to non-infectious diseases/conditions. We added a gender inequality and a life course lens to the above framework to identify whether WASH affected health of mothers in particular, and acted beyond the immediate effects. This framework led us to identifying 77 risk mechanisms (67 chemical or biological factors and 10 complex behavioural factors) linking WASH to maternal and perinatal health outcomes.
WASH affects the risk of adverse maternal and perinatal health outcomes; these exposures are multiple and overlapping and may be distant from the immediate health outcome. Much of the evidence is weak, based on observational studies and anecdotal evidence, with relatively few systematic reviews. New systematic reviews are required to assess the quality of existing evidence more rigorously, and primary research is required to investigate the magnitude of effects of particular WASH exposures on specific maternal and perinatal outcomes. Whilst major gaps exist, the evidence strongly suggests that poor WASH influences maternal and reproductive health outcomes to the extent that it should be considered in global and national strategies.
Url:
DOI: 10.1111/tmi.12439
PubMed: 25430609
PubMed Central: 4681319
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PMC:4681319Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Getting the basic rights – the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework</title><author><name sortKey="Campbell, Oona M R" sort="Campbell, Oona M R" uniqKey="Campbell O" first="Oona M R" last="Campbell">Oona M R. Campbell</name><affiliation><nlm:aff id="au1"><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Benova, Lenka" sort="Benova, Lenka" uniqKey="Benova L" first="Lenka" last="Benova">Lenka Benova</name><affiliation><nlm:aff id="au1"><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Gon, Giorgia" sort="Gon, Giorgia" uniqKey="Gon G" first="Giorgia" last="Gon">Giorgia Gon</name><affiliation><nlm:aff id="au1"><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Afsana, Kaosar" sort="Afsana, Kaosar" uniqKey="Afsana K" first="Kaosar" last="Afsana">Kaosar Afsana</name><affiliation><nlm:aff id="au2"><institution>BRAC, Health, Nutrition and Population and BRAC University, James P Grant School of Public Health</institution><addr-line>Dhaka, Bangladesh</addr-line></nlm:aff></affiliation></author><author><name sortKey="Cumming, Oliver" sort="Cumming, Oliver" uniqKey="Cumming O" first="Oliver" last="Cumming">Oliver Cumming</name><affiliation><nlm:aff id="au3"><institution>Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25430609</idno><idno type="pmc">4681319</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681319</idno><idno type="RBID">PMC:4681319</idno><idno type="doi">10.1111/tmi.12439</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000247</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000247</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Getting the basic rights – the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework</title><author><name sortKey="Campbell, Oona M R" sort="Campbell, Oona M R" uniqKey="Campbell O" first="Oona M R" last="Campbell">Oona M R. Campbell</name><affiliation><nlm:aff id="au1"><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Benova, Lenka" sort="Benova, Lenka" uniqKey="Benova L" first="Lenka" last="Benova">Lenka Benova</name><affiliation><nlm:aff id="au1"><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Gon, Giorgia" sort="Gon, Giorgia" uniqKey="Gon G" first="Giorgia" last="Gon">Giorgia Gon</name><affiliation><nlm:aff id="au1"><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author><author><name sortKey="Afsana, Kaosar" sort="Afsana, Kaosar" uniqKey="Afsana K" first="Kaosar" last="Afsana">Kaosar Afsana</name><affiliation><nlm:aff id="au2"><institution>BRAC, Health, Nutrition and Population and BRAC University, James P Grant School of Public Health</institution><addr-line>Dhaka, Bangladesh</addr-line></nlm:aff></affiliation></author><author><name sortKey="Cumming, Oliver" sort="Cumming, Oliver" uniqKey="Cumming O" first="Oliver" last="Cumming">Oliver Cumming</name><affiliation><nlm:aff id="au3"><institution>Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></nlm:aff></affiliation></author></analytic><series><title level="j">Tropical Medicine & International Health</title><idno type="ISSN">1360-2276</idno><idno type="eISSN">1365-3156</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Objective</title><p>To explore linkages between water, sanitation and hygiene (WASH) and maternal and perinatal health via a conceptual approach and a scoping review.</p></sec><sec><title>Methods</title><p>We developed a conceptual framework iteratively, amalgamating three literature-based lenses. We then searched literature and identified risk factors potentially linked to maternal and perinatal health. We conducted a systematic scoping review for all chemical and biological WASH risk factors identified using text and MeSH terms, limiting results to systematic reviews or meta-analyses. The remaining 10 complex behavioural associations were not reviewed systematically.</p></sec><sec><title>Results</title><p>The main ways poor WASH could lead to adverse outcomes are via two non-exclusive categories: 1. ‘In-water’ associations: (a) Inorganic contaminants, and (b) ‘water-system’ related infections, (c) ‘water-based’ infections, and (d) ‘water borne’ infections. 2. ‘Behaviour’ associations: (e) Behaviours leading to water-washed infections, (f) Water-related insect-vector infections, and (g-i) Behaviours leading to non-infectious diseases/conditions. We added a gender inequality and a life course lens to the above framework to identify whether WASH affected health of mothers in particular, and acted beyond the immediate effects. This framework led us to identifying 77 risk mechanisms (67 chemical or biological factors and 10 complex behavioural factors) linking WASH to maternal and perinatal health outcomes.</p></sec><sec><title>Conclusion</title><p>WASH affects the risk of adverse maternal and perinatal health outcomes; these exposures are multiple and overlapping and may be distant from the immediate health outcome. Much of the evidence is weak, based on observational studies and anecdotal evidence, with relatively few systematic reviews. New systematic reviews are required to assess the quality of existing evidence more rigorously, and primary research is required to investigate the magnitude of effects of particular WASH exposures on specific maternal and perinatal outcomes. Whilst major gaps exist, the evidence strongly suggests that poor WASH influences maternal and reproductive health outcomes to the extent that it should be considered in global and national strategies.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abdelgadir, M" uniqKey="Abdelgadir M">M Abdelgadir</name></author><author><name sortKey="Khalid, A" uniqKey="Khalid A">A Khalid</name></author><author><name sortKey="Ashmaig, A" uniqKey="Ashmaig A">A Ashmaig</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abioye Kuteyi, E" uniqKey="Abioye Kuteyi E">E Abioye-Kuteyi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adegnika, A" uniqKey="Adegnika A">A Adegnika</name></author><author><name sortKey="Kremsner, P" uniqKey="Kremsner P">P Kremsner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Adugna, A" uniqKey="Adugna A">A Adugna</name></author><author><name sortKey="Dery, M" uniqKey="Dery M">M Dery</name></author><author><name sortKey="Gomme, J" uniqKey="Gomme J">J Gomme</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aggarwal, R" uniqKey="Aggarwal R">R Aggarwal</name></author><author><name sortKey="Naik, S" uniqKey="Naik S">S Naik</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ahmed, R" uniqKey="Ahmed R">R Ahmed</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ali, T" uniqKey="Ali T">T Ali</name></author><author><name sortKey="Fikree, F" uniqKey="Fikree F">F Fikree</name></author><author><name sortKey="Rahbar, M" uniqKey="Rahbar M">M Rahbar</name></author><author><name sortKey="Mahmud, S" uniqKey="Mahmud S">S Mahmud</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Amiri, Fn" uniqKey="Amiri F">FN Amiri</name></author><author><name sortKey="Rooshan, Mh" uniqKey="Rooshan M">MH Rooshan</name></author><author><name sortKey="Ahmady, Mh" uniqKey="Ahmady M">MH Ahmady</name></author><author><name sortKey="Soliamani, Mj" uniqKey="Soliamani M">MJ Soliamani</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Arksey, H" uniqKey="Arksey H">H Arksey</name></author><author><name sortKey="O Malley, L" uniqKey="O Malley L">L O'Malley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aschengrau, A" uniqKey="Aschengrau A">A Aschengrau</name></author><author><name sortKey="Zierler, S" uniqKey="Zierler S">S Zierler</name></author><author><name sortKey="Cohen, A" uniqKey="Cohen A">A Cohen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ashbolt, N" uniqKey="Ashbolt N">N Ashbolt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Balabani, D" uniqKey="Balabani D">D Balabanič</name></author><author><name sortKey="Rupnik, M" uniqKey="Rupnik M">M Rupnik</name></author><author><name sortKey="Klemen I, A" uniqKey="Klemen I A">A Klemenčič</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bardasi, E" uniqKey="Bardasi E">E Bardasi</name></author><author><name sortKey="Wodon, Q" uniqKey="Wodon Q">Q Wodon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barker, D" uniqKey="Barker D">D Barker</name></author><author><name sortKey="Forsen, T" uniqKey="Forsen T">T Forsén</name></author><author><name sortKey="Eriksson, J" uniqKey="Eriksson J">J Eriksson</name></author><author><name sortKey="Osmond, C" uniqKey="Osmond C">C Osmond</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barros, Fc" uniqKey="Barros F">FC Barros</name></author><author><name sortKey="Bhutta, Za" uniqKey="Bhutta Z">ZA Bhutta</name></author><author><name sortKey="Batra, M" uniqKey="Batra M">M Batra</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bartram, J" uniqKey="Bartram J">J Bartram</name></author><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bartram, J" uniqKey="Bartram J">J Bartram</name></author><author><name sortKey="Chartier, Y" uniqKey="Chartier Y">Y Chartier</name></author><author><name sortKey="Lee, J" uniqKey="Lee J">J Lee</name></author><author><name sortKey="Pond, K" uniqKey="Pond K">K Pond</name></author><author><name sortKey="Surman Lee, S" uniqKey="Surman Lee S">S Surman-Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bellinger, D" uniqKey="Bellinger D">D Bellinger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benova, L" uniqKey="Benova L">L Benova</name></author><author><name sortKey="Cumming, O" uniqKey="Cumming O">O Cumming</name></author><author><name sortKey="Campbell, O" uniqKey="Campbell O">O Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Benova, L" uniqKey="Benova L">L Benova</name></author><author><name sortKey="Cumming, O" uniqKey="Cumming O">O Cumming</name></author><author><name sortKey="Gordon, B" uniqKey="Gordon B">B Gordon</name></author><author><name sortKey="Magoma, M" uniqKey="Magoma M">M Magoma</name></author><author><name sortKey="Campbell, O" uniqKey="Campbell O">O Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ben Shlomo, Y" uniqKey="Ben Shlomo Y">Y Ben-Shlomo</name></author><author><name sortKey="Kuh, D" uniqKey="Kuh D">D Kuh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Birdthistle, I" uniqKey="Birdthistle I">I Birdthistle</name></author><author><name sortKey="Dickson, K" uniqKey="Dickson K">K Dickson</name></author><author><name sortKey="Freeman, M" uniqKey="Freeman M">M Freeman</name></author><author><name sortKey="Javidi, L" uniqKey="Javidi L">L Javidi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bledsoe, C" uniqKey="Bledsoe C">C Bledsoe</name></author><author><name sortKey="Hill, A" uniqKey="Hill A">A Hill</name></author><author><name sortKey="Langerock, P" uniqKey="Langerock P">P Langerock</name></author><author><name sortKey="D Alessandro, U" uniqKey="D Alessandro U">U D'Alessandro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bo, Z" uniqKey="Bo Z">Z Bo</name></author><author><name sortKey="Mei, H" uniqKey="Mei H">H Mei</name></author><author><name sortKey="Yongsheng, Z" uniqKey="Yongsheng Z">Z Yongsheng</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Boel, Me" uniqKey="Boel M">ME Boel</name></author><author><name sortKey="Rijken, Mj" uniqKey="Rijken M">MJ Rijken</name></author><author><name sortKey="Brabin, Bj" uniqKey="Brabin B">BJ Brabin</name></author><author><name sortKey="Nosten, F" uniqKey="Nosten F">F Nosten</name></author><author><name sortKey="Mcgready, R" uniqKey="Mcgready R">R McGready</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brabin, B" uniqKey="Brabin B">B Brabin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brooker, S" uniqKey="Brooker S">S Brooker</name></author><author><name sortKey="Hotez, Pj" uniqKey="Hotez P">PJ Hotez</name></author><author><name sortKey="Bundy, Dap" uniqKey="Bundy D">DAP Bundy</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, K" uniqKey="Brown K">K Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Buttke, D" uniqKey="Buttke D">D Buttke</name></author><author><name sortKey="Sircar, K" uniqKey="Sircar K">K Sircar</name></author><author><name sortKey="Martin, C" uniqKey="Martin C">C Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author><author><name sortKey="Cliff, J" uniqKey="Cliff J">J Cliff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author><author><name sortKey="Feachem, R" uniqKey="Feachem R">R Feachem</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author><author><name sortKey="Kinnear, J" uniqKey="Kinnear J">J Kinnear</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author><author><name sortKey="Valdmanis, V" uniqKey="Valdmanis V">V Valdmanis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author><author><name sortKey="Blumenthal, U" uniqKey="Blumenthal U">U Blumenthal</name></author><author><name sortKey="Kolsky, P" uniqKey="Kolsky P">P Kolsky</name></author><author><name sortKey="Moraes, L" uniqKey="Moraes L">L Moraes</name></author><author><name sortKey="Tayeh, A" uniqKey="Tayeh A">A Tayeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Calderon, R" uniqKey="Calderon R">R Calderon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caserta, D" uniqKey="Caserta D">D Caserta</name></author><author><name sortKey="Mantovani, A" uniqKey="Mantovani A">A Mantovani</name></author><author><name sortKey="Marci, R" uniqKey="Marci R">R Marci</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Caserta, D" uniqKey="Caserta D">D Caserta</name></author><author><name sortKey="Matteucci, E" uniqKey="Matteucci E">E Matteucci</name></author><author><name sortKey="Ralli, E" uniqKey="Ralli E">E Ralli</name></author><author><name sortKey="Moscarini, M" uniqKey="Moscarini M">M Moscarini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cedergren, M" uniqKey="Cedergren M">M Cedergren</name></author><author><name sortKey="Selbing, A" uniqKey="Selbing A">A Selbing</name></author><author><name sortKey="Lofman, O" uniqKey="Lofman O">O Lofman</name></author><author><name sortKey="Kallen, B" uniqKey="Kallen B">B Kallen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Checkley, W" uniqKey="Checkley W">W Checkley</name></author><author><name sortKey="Buckley, G" uniqKey="Buckley G">G Buckley</name></author><author><name sortKey="Gilman, R" uniqKey="Gilman R">R Gilman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cherry, N" uniqKey="Cherry N">N Cherry</name></author><author><name sortKey="Shaikh, K" uniqKey="Shaikh K">K Shaikh</name></author><author><name sortKey="Mcdonald, C" uniqKey="Mcdonald C">C McDonald</name></author><author><name sortKey="Chowdhury, Z" uniqKey="Chowdhury Z">Z Chowdhury</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chico, R" uniqKey="Chico R">R Chico</name></author><author><name sortKey="Mayaud, P" uniqKey="Mayaud P">P Mayaud</name></author><author><name sortKey="Ariti, C" uniqKey="Ariti C">C Ariti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chopra, M" uniqKey="Chopra M">M Chopra</name></author><author><name sortKey="Sharkey, A" uniqKey="Sharkey A">A Sharkey</name></author><author><name sortKey="Dalmiya, N" uniqKey="Dalmiya N">N Dalmiya</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Christian, P" uniqKey="Christian P">P Christian</name></author><author><name sortKey="Khatry, S" uniqKey="Khatry S">S Khatry</name></author><author><name sortKey="West, K" uniqKey="West K">K West</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Conde Agudelo, A" uniqKey="Conde Agudelo A">A Conde-Agudelo</name></author><author><name sortKey="Villar, J" uniqKey="Villar J">J Villar</name></author><author><name sortKey="Lindheimer, M" uniqKey="Lindheimer M">M Lindheimer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Curtis, C" uniqKey="Curtis C">C Curtis</name></author><author><name sortKey="Minjas, J" uniqKey="Minjas J">J Minjas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dar, Oa" uniqKey="Dar O">OA Dar</name></author><author><name sortKey="Khan, Ms" uniqKey="Khan M">MS Khan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Darmstadt, G" uniqKey="Darmstadt G">G Darmstadt</name></author><author><name sortKey="Hasan, M" uniqKey="Hasan M">M Hasan</name></author><author><name sortKey="Balsara, Z" uniqKey="Balsara Z">Z Balsara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Deen, J" uniqKey="Deen J">J Deen</name></author><author><name sortKey="Von Seidlein, L" uniqKey="Von Seidlein L">L von Seidlein</name></author><author><name sortKey="Andersen, F" uniqKey="Andersen F">F Andersen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Demicheli, V" uniqKey="Demicheli V">V Demicheli</name></author><author><name sortKey="Barale, A" uniqKey="Barale A">A Barale</name></author><author><name sortKey="Rivetti, A" uniqKey="Rivetti A">A Rivetti</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Desai, M" uniqKey="Desai M">M Desai</name></author><author><name sortKey="Ter Kuile, F" uniqKey="Ter Kuile F">F ter Kuile</name></author><author><name sortKey="Nosten, F" uniqKey="Nosten F">F Nosten</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Diouf, M" uniqKey="Diouf M">M Diouf</name></author><author><name sortKey="Cisse, D" uniqKey="Cisse D">D Cisse</name></author><author><name sortKey="Lo, C" uniqKey="Lo C">C Lo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Dufaut, A" uniqKey="Dufaut A">A Dufaut</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ekong, E" uniqKey="Ekong E">E Ekong</name></author><author><name sortKey="Jaar, B" uniqKey="Jaar B">B Jaar</name></author><author><name sortKey="Weaver, V" uniqKey="Weaver V">V Weaver</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Elias, D" uniqKey="Elias D">D Elias</name></author><author><name sortKey="Britton, S" uniqKey="Britton S">S Britton</name></author><author><name sortKey="Kassu, A" uniqKey="Kassu A">A Kassu</name></author><author><name sortKey="Akuffo, H" uniqKey="Akuffo H">H Akuffo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Emerson, Su" uniqKey="Emerson S">SU Emerson</name></author><author><name sortKey="Purcell, Rh" uniqKey="Purcell R">RH Purcell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ezzati, M" uniqKey="Ezzati M">M Ezzati</name></author><author><name sortKey="Utzinger, J" uniqKey="Utzinger J">J Utzinger</name></author><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author><author><name sortKey="Cohen, A" uniqKey="Cohen A">A Cohen</name></author><author><name sortKey="Singer, B" uniqKey="Singer B">B Singer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fakeye, O" uniqKey="Fakeye O">O Fakeye</name></author><author><name sortKey="Adegoke, A" uniqKey="Adegoke A">A Adegoke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fauveau, V" uniqKey="Fauveau V">V Fauveau</name></author><author><name sortKey="Mamdani, M" uniqKey="Mamdani M">M Mamdani</name></author><author><name sortKey="Steinglass, R" uniqKey="Steinglass R">R Steinglass</name></author><author><name sortKey="Koblinsky, M" uniqKey="Koblinsky M">M Koblinsky</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feldmeier, H" uniqKey="Feldmeier H">H Feldmeier</name></author><author><name sortKey="Poggensee, G" uniqKey="Poggensee G">G Poggensee</name></author><author><name sortKey="Krantz, I" uniqKey="Krantz I">I Krantz</name></author><author><name sortKey="Helling Giese, G" uniqKey="Helling Giese G">G Helling-Giese</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ferris, Itj" uniqKey="Ferris I">ITJ Ferris</name></author><author><name sortKey="Ortega Garcia, Ja" uniqKey="Ortega Garcia J">JA Ortega Garcia</name></author><author><name sortKey="Garcia, Icj" uniqKey="Garcia I">ICJ Garcia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fewtrell, L" uniqKey="Fewtrell L">L Fewtrell</name></author><author><name sortKey="Fuge, R" uniqKey="Fuge R">R Fuge</name></author><author><name sortKey="Kay, D" uniqKey="Kay D">D Kay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Figa Talamanca, I" uniqKey="Figa Talamanca I">I Figà-Talamanca</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fincham, J" uniqKey="Fincham J">J Fincham</name></author><author><name sortKey="Markus, M" uniqKey="Markus M">M Markus</name></author><author><name sortKey="Adams, V" uniqKey="Adams V">V Adams</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fischer Walker, C" uniqKey="Fischer Walker C">C Fischer Walker</name></author><author><name sortKey="Perin, J" uniqKey="Perin J">J Perin</name></author><author><name sortKey="Aryee, M" uniqKey="Aryee M">M Aryee</name></author><author><name sortKey="Boschi Pinto, C" uniqKey="Boschi Pinto C">C Boschi-Pinto</name></author><author><name sortKey="Black, R" uniqKey="Black R">R Black</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Florack, E" uniqKey="Florack E">E Florack</name></author><author><name sortKey="Zielhuis, G" uniqKey="Zielhuis G">G Zielhuis</name></author><author><name sortKey="Pellegrino, J" uniqKey="Pellegrino J">J Pellegrino</name></author><author><name sortKey="Rolland, R" uniqKey="Rolland R">R Rolland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fowler, P" uniqKey="Fowler P">P Fowler</name></author><author><name sortKey="Bellingham, M" uniqKey="Bellingham M">M Bellingham</name></author><author><name sortKey="Sinclair, K" uniqKey="Sinclair K">K Sinclair</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gadgil, A" uniqKey="Gadgil A">A Gadgil</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gil, A" uniqKey="Gil A">A Gil</name></author><author><name sortKey="Lanata, C" uniqKey="Lanata C">C Lanata</name></author><author><name sortKey="Kleinau, E" uniqKey="Kleinau E">E Kleinau</name></author><author><name sortKey="Penny, M" uniqKey="Penny M">M Penny</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Goldenberg, Rl" uniqKey="Goldenberg R">RL Goldenberg</name></author><author><name sortKey="Thompson, C" uniqKey="Thompson C">C Thompson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gon, G" uniqKey="Gon G">G Gon</name></author><author><name sortKey="Monzon Llamas, L" uniqKey="Monzon Llamas L">L Monzon-Llamas</name></author><author><name sortKey="Benova, L" uniqKey="Benova L">L Benova</name></author><author><name sortKey="Willey, B" uniqKey="Willey B">B Willey</name></author><author><name sortKey="Campbell, O" uniqKey="Campbell O">O Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gordon, A" uniqKey="Gordon A">A Gordon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Grellier, J" uniqKey="Grellier J">J Grellier</name></author><author><name sortKey="Bennett, J" uniqKey="Bennett J">J Bennett</name></author><author><name sortKey="Patelarou, E" uniqKey="Patelarou E">E Patelarou</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guerrant, R" uniqKey="Guerrant R">R Guerrant</name></author><author><name sortKey="Kosek, M" uniqKey="Kosek M">M Kosek</name></author><author><name sortKey="Moore, S" uniqKey="Moore S">S Moore</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guerrant, R" uniqKey="Guerrant R">R Guerrant</name></author><author><name sortKey="Deboer, M" uniqKey="Deboer M">M Deboer</name></author><author><name sortKey="Moore, S" uniqKey="Moore S">S Moore</name></author><author><name sortKey="Scharf, R" uniqKey="Scharf R">R Scharf</name></author><author><name sortKey="Lima, A" uniqKey="Lima A">A Lima</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Gyapong, J" uniqKey="Gyapong J">J Gyapong</name></author><author><name sortKey="Chinbuah, M" uniqKey="Chinbuah M">M Chinbuah</name></author><author><name sortKey="Gyapong, M" uniqKey="Gyapong M">M Gyapong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hannan, C" uniqKey="Hannan C">C Hannan</name></author><author><name sortKey="Andersson, I" uniqKey="Andersson I">I Andersson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Henderson, L" uniqKey="Henderson L">L Henderson</name></author><author><name sortKey="Tulloch, J" uniqKey="Tulloch J">J Tulloch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Heymann, Dl" uniqKey="Heymann D">DL Heymann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horton, R" uniqKey="Horton R">R Horton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ilahi, N" uniqKey="Ilahi N">N Ilahi</name></author><author><name sortKey="Grimard, F" uniqKey="Grimard F">F Grimard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ishaque, S" uniqKey="Ishaque S">S Ishaque</name></author><author><name sortKey="Yakoob, My" uniqKey="Yakoob M">MY Yakoob</name></author><author><name sortKey="Imdad, A" uniqKey="Imdad A">A Imdad</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jamieson, D" uniqKey="Jamieson D">D Jamieson</name></author><author><name sortKey="Theiler, R" uniqKey="Theiler R">R Theiler</name></author><author><name sortKey="Rasmussen, S" uniqKey="Rasmussen S">S Rasmussen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Janakiraman, V" uniqKey="Janakiraman V">V Janakiraman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jones, R" uniqKey="Jones R">R Jones</name></author><author><name sortKey="Finlay, F" uniqKey="Finlay F">F Finlay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jorgensen, S" uniqKey="Jorgensen S">S Jorgensen</name></author><author><name sortKey="Hein, H" uniqKey="Hein H">H Hein</name></author><author><name sortKey="Gyntelberg, F" uniqKey="Gyntelberg F">F Gyntelberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Khan, A" uniqKey="Khan A">A Khan</name></author><author><name sortKey="Ireson, A" uniqKey="Ireson A">A Ireson</name></author><author><name sortKey="Kovats, S" uniqKey="Kovats S">S Kovats</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="King, W" uniqKey="King W">W King</name></author><author><name sortKey="Dodds, L" uniqKey="Dodds L">L Dodds</name></author><author><name sortKey="Allen, A" uniqKey="Allen A">A Allen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="King, C" uniqKey="King C">C King</name></author><author><name sortKey="Dickman, K" uniqKey="Dickman K">K Dickman</name></author><author><name sortKey="Tisch, D" uniqKey="Tisch D">D Tisch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kirschstein, R" uniqKey="Kirschstein R">R Kirschstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kistemann, T" uniqKey="Kistemann T">T Kistemann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koolwal, G" uniqKey="Koolwal G">G Koolwal</name></author><author><name sortKey="Van De Walle, D" uniqKey="Van De Walle D">D van de Walle</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kourtis, Ap" uniqKey="Kourtis A">AP Kourtis</name></author><author><name sortKey="Read, Js" uniqKey="Read J">JS Read</name></author><author><name sortKey="Jamieson, Dj" uniqKey="Jamieson D">DJ Jamieson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krieger, N" uniqKey="Krieger N">N Krieger</name></author><author><name sortKey="Zierler, S" uniqKey="Zierler S">S Zierler</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kuh, D" uniqKey="Kuh D">D Kuh</name></author><author><name sortKey="Ben Shlomo, Y" uniqKey="Ben Shlomo Y">Y Ben-Shlomo</name></author><author><name sortKey="Lynch, J" uniqKey="Lynch J">J Lynch</name></author><author><name sortKey="Hallqvist, J" uniqKey="Hallqvist J">J Hallqvist</name></author><author><name sortKey="Power, C" uniqKey="Power C">C Power</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kurtis, J" uniqKey="Kurtis J">J Kurtis</name></author><author><name sortKey="Higashi, A" uniqKey="Higashi A">A Higashi</name></author><author><name sortKey="Wu, H" uniqKey="Wu H">H Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lamont, Rf" uniqKey="Lamont R">RF Lamont</name></author><author><name sortKey="Sobel, J" uniqKey="Sobel J">J Sobel</name></author><author><name sortKey="Mazaki Tovi, S" uniqKey="Mazaki Tovi S">S Mazaki-Tovi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lawson, D" uniqKey="Lawson D">D Lawson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Le Hesran, J" uniqKey="Le Hesran J">J Le Hesran</name></author><author><name sortKey="Akiana, J" uniqKey="Akiana J">J Akiana</name></author><author><name sortKey="Ndiaye, E" uniqKey="Ndiaye E">E Ndiaye</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lennon, S" uniqKey="Lennon S">S Lennon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lettieri, L" uniqKey="Lettieri L">L Lettieri</name></author><author><name sortKey="Vintzileos, Am" uniqKey="Vintzileos A">AM Vintzileos</name></author><author><name sortKey="Rodis, Jf" uniqKey="Rodis J">JF Rodis</name></author><author><name sortKey="Albini, Sm" uniqKey="Albini S">SM Albini</name></author><author><name sortKey="Salafia, Cm" uniqKey="Salafia C">CM Salafia</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levac, D" uniqKey="Levac D">D Levac</name></author><author><name sortKey="Colquhoun, H" uniqKey="Colquhoun H">H Colquhoun</name></author><author><name sortKey="O Brien, Kk" uniqKey="O Brien K">KK O'Brien</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lima, A" uniqKey="Lima A">A Lima</name></author><author><name sortKey="Moore, S" uniqKey="Moore S">S Moore</name></author><author><name sortKey="Barboza, Mj" uniqKey="Barboza M">MJ Barboza</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lindner, Ak" uniqKey="Lindner A">AK Lindner</name></author><author><name sortKey="Priotto, G" uniqKey="Priotto G">G Priotto</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Liu, L" uniqKey="Liu L">L Liu</name></author><author><name sortKey="Johnson, H" uniqKey="Johnson H">H Johnson</name></author><author><name sortKey="Cousens, S" uniqKey="Cousens S">S Cousens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lopez Duenas, A" uniqKey="Lopez Duenas A">A Lopez Duenas</name></author><author><name sortKey="Aldea Romero, Ae" uniqKey="Aldea Romero A">AE Aldea Romero</name></author><author><name sortKey="Sanz Anquela, Jm" uniqKey="Sanz Anquela J">JM Sanz Anquela</name></author><author><name sortKey="Jimenez Bustos, Jm" uniqKey="Jimenez Bustos J">JM Jimenez Bustos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Maduka, C" uniqKey="Maduka C">C Maduka</name></author><author><name sortKey="Nweke, L" uniqKey="Nweke L">L Nweke</name></author><author><name sortKey="Miri, E" uniqKey="Miri E">E Miri</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Main, E" uniqKey="Main E">E Main</name></author><author><name sortKey="Morton, Ch" uniqKey="Morton C">CH Morton</name></author><author><name sortKey="Melsop, Km" uniqKey="Melsop K">KM Melsop</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mamman, L" uniqKey="Mamman L">L Mamman</name></author><author><name sortKey="Brieger, W" uniqKey="Brieger W">W Brieger</name></author><author><name sortKey="Oshiname, F" uniqKey="Oshiname F">F Oshiname</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Manassaram, D" uniqKey="Manassaram D">D Manassaram</name></author><author><name sortKey="Backer, L" uniqKey="Backer L">L Backer</name></author><author><name sortKey="Moll, D" uniqKey="Moll D">D Moll</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Massey, K" uniqKey="Massey K">K Massey</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mazor Dray, E" uniqKey="Mazor Dray E">E Mazor-Dray</name></author><author><name sortKey="Levy, A" uniqKey="Levy A">A Levy</name></author><author><name sortKey="Schlaeffer, F" uniqKey="Schlaeffer F">F Schlaeffer</name></author><author><name sortKey="Sheiner, E" uniqKey="Sheiner E">E Sheiner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mcgready, R" uniqKey="Mcgready R">R McGready</name></author><author><name sortKey="Lee, S" uniqKey="Lee S">S Lee</name></author><author><name sortKey="Wiladphaingern, J" uniqKey="Wiladphaingern J">J Wiladphaingern</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Menezes, Ev" uniqKey="Menezes E">EV Menezes</name></author><author><name sortKey="Yakoob, My" uniqKey="Yakoob M">MY Yakoob</name></author><author><name sortKey="Soomro, T" uniqKey="Soomro T">T Soomro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Miles, Mb" uniqKey="Miles M">MB Miles</name></author><author><name sortKey="Huberman, Am" uniqKey="Huberman A">AM Huberman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Milton, Ah" uniqKey="Milton A">AH Milton</name></author><author><name sortKey="Smith, W" uniqKey="Smith W">W Smith</name></author><author><name sortKey="Rahman, B" uniqKey="Rahman B">B Rahman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minassian, C" uniqKey="Minassian C">C Minassian</name></author><author><name sortKey="Thomas, Sl" uniqKey="Thomas S">SL Thomas</name></author><author><name sortKey="Williams, Dj" uniqKey="Williams D">DJ Williams</name></author><author><name sortKey="Campbell, O" uniqKey="Campbell O">O Campbell</name></author><author><name sortKey="Smeeth, L" uniqKey="Smeeth L">L Smeeth</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mishra, G" uniqKey="Mishra G">G Mishra</name></author><author><name sortKey="Cooper, R" uniqKey="Cooper R">R Cooper</name></author><author><name sortKey="Kuh, D" uniqKey="Kuh D">D Kuh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moist, L" uniqKey="Moist L">L Moist</name></author><author><name sortKey="Sontrop, J" uniqKey="Sontrop J">J Sontrop</name></author><author><name sortKey="Garg, A" uniqKey="Garg A">A Garg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mosby, Lg" uniqKey="Mosby L">LG Mosby</name></author><author><name sortKey="Rasmussen, Sa" uniqKey="Rasmussen S">SA Rasmussen</name></author><author><name sortKey="Jamieson, Dj" uniqKey="Jamieson D">DJ Jamieson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mota, A" uniqKey="Mota A">A Mota</name></author><author><name sortKey="Miranda Filho, A" uniqKey="Miranda Filho A">A Miranda Filho</name></author><author><name sortKey="Saraceni, V" uniqKey="Saraceni V">V Saraceni</name></author><author><name sortKey="Koifman, S" uniqKey="Koifman S">S Koifman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Moubayed, P" uniqKey="Moubayed P">P Moubayed</name></author><author><name sortKey="Ziehe, A" uniqKey="Ziehe A">A Ziehe</name></author><author><name sortKey="Peters, J" uniqKey="Peters J">J Peters</name></author><author><name sortKey="Mwakyoma, H" uniqKey="Mwakyoma H">H Mwakyoma</name></author><author><name sortKey="Schmidt, D" uniqKey="Schmidt D">D Schmidt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mukhtar, M" uniqKey="Mukhtar M">M Mukhtar</name></author><author><name sortKey="Ensink, J" uniqKey="Ensink J">J Ensink</name></author><author><name sortKey="Van Der Hoek, W" uniqKey="Van Der Hoek W">W van der Hoek</name></author><author><name sortKey="Amerasinghe, F" uniqKey="Amerasinghe F">F Amerasinghe</name></author><author><name sortKey="Konradsen, F" uniqKey="Konradsen F">F Konradsen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Murray, C" uniqKey="Murray C">C Murray</name></author><author><name sortKey="Vos, T" uniqKey="Vos T">T Vos</name></author><author><name sortKey="Lozano, R" uniqKey="Lozano R">R Lozano</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nauges, C" uniqKey="Nauges C">C Nauges</name></author><author><name sortKey="Strand, J" uniqKey="Strand J">J Strand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nicolle Mir, L" uniqKey="Nicolle Mir L">L Nicolle-Mir</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nolan, C" uniqKey="Nolan C">C Nolan</name></author><author><name sortKey="Shaikh, Z" uniqKey="Shaikh Z">Z Shaikh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Noronha, Ja" uniqKey="Noronha J">JA Noronha</name></author><author><name sortKey="Al Khasawneh, E" uniqKey="Al Khasawneh E">E Al Khasawneh</name></author><author><name sortKey="Seshan, V" uniqKey="Seshan V">V Seshan</name></author><author><name sortKey="Ramasubramaniam, S" uniqKey="Ramasubramaniam S">S Ramasubramaniam</name></author><author><name sortKey="Raman, S" uniqKey="Raman S">S Raman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Novak, J" uniqKey="Novak J">J Novak</name></author><author><name sortKey="Canas, A" uniqKey="Canas A">A Canas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nygaard, I" uniqKey="Nygaard I">I Nygaard</name></author><author><name sortKey="Linder, M" uniqKey="Linder M">M Linder</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Peters, C" uniqKey="Peters C">C Peters</name></author><author><name sortKey="Harling, M" uniqKey="Harling M">M Harling</name></author><author><name sortKey="Dulon, M" uniqKey="Dulon M">M Dulon</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pocock, S" uniqKey="Pocock S">S Pocock</name></author><author><name sortKey="Smith, M" uniqKey="Smith M">M Smith</name></author><author><name sortKey="Baghurst, P" uniqKey="Baghurst P">P Baghurst</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Potukuchi, P" uniqKey="Potukuchi P">P Potukuchi</name></author><author><name sortKey="Rao, P" uniqKey="Rao P">P Rao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pouliot, S" uniqKey="Pouliot S">S Pouliot</name></author><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Harville, E" uniqKey="Harville E">E Harville</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pruss Stun, A" uniqKey="Pruss Stun A">A Prüss-Üstün</name></author><author><name sortKey="Bos, R" uniqKey="Bos R">R Bos</name></author><author><name sortKey="Gore, F" uniqKey="Gore F">F Gore</name></author><author><name sortKey="Bartram, J" uniqKey="Bartram J">J Bartram</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Qunhua, L" uniqKey="Qunhua L">L Qunhua</name></author><author><name sortKey="Jiawen, Z" uniqKey="Jiawen Z">Z Jiawen</name></author><author><name sortKey="Bozhao, L" uniqKey="Bozhao L">L Bozhao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rabie, T" uniqKey="Rabie T">T Rabie</name></author><author><name sortKey="Curtis, V" uniqKey="Curtis V">V Curtis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rahman, A" uniqKey="Rahman A">A Rahman</name></author><author><name sortKey="Vahter, M" uniqKey="Vahter M">M Vahter</name></author><author><name sortKey="Ekstrom, Ec" uniqKey="Ekstrom E">EC Ekstrom</name></author><author><name sortKey="Rahman, M" uniqKey="Rahman M">M Rahman</name></author><author><name sortKey="Haider, A" uniqKey="Haider A">A Haider</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rahman, A" uniqKey="Rahman A">A Rahman</name></author><author><name sortKey="Persson, La" uniqKey="Persson L">LA Persson</name></author><author><name sortKey="Nermell, B" uniqKey="Nermell B">B Nermell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Reddy, E" uniqKey="Reddy E">E Reddy</name></author><author><name sortKey="Shaw, A" uniqKey="Shaw A">A Shaw</name></author><author><name sortKey="Crump, J" uniqKey="Crump J">J Crump</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rein, D" uniqKey="Rein D">D Rein</name></author><author><name sortKey="Stevens, G" uniqKey="Stevens G">G Stevens</name></author><author><name sortKey="Theaker, J" uniqKey="Theaker J">J Theaker</name></author><author><name sortKey="Wittenborn, J" uniqKey="Wittenborn J">J Wittenborn</name></author><author><name sortKey="Wiersma, S" uniqKey="Wiersma S">S Wiersma</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rich Edwards, J" uniqKey="Rich Edwards J">J Rich-Edwards</name></author><author><name sortKey="Stampfer, M" uniqKey="Stampfer M">M Stampfer</name></author><author><name sortKey="Manson, J" uniqKey="Manson J">J Manson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Roper, M" uniqKey="Roper M">M Roper</name></author><author><name sortKey="Vandelaer, J" uniqKey="Vandelaer J">J Vandelaer</name></author><author><name sortKey="Gasse, F" uniqKey="Gasse F">F Gasse</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosen, S" uniqKey="Rosen S">S Rosen</name></author><author><name sortKey="Vincent, J" uniqKey="Vincent J">J Vincent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rossi, A" uniqKey="Rossi A">A Rossi</name></author><author><name sortKey="D Addario, V" uniqKey="D Addario V">V D'Addario</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ruma, M" uniqKey="Ruma M">M Ruma</name></author><author><name sortKey="Boggess, K" uniqKey="Boggess K">K Boggess</name></author><author><name sortKey="Moss, K" uniqKey="Moss K">K Moss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schieve, L" uniqKey="Schieve L">L Schieve</name></author><author><name sortKey="Handler, A" uniqKey="Handler A">A Handler</name></author><author><name sortKey="Hershow, R" uniqKey="Hershow R">R Hershow</name></author><author><name sortKey="Persky, V" uniqKey="Persky V">V Persky</name></author><author><name sortKey="Davis, F" uniqKey="Davis F">F Davis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semba, R" uniqKey="Semba R">R Semba</name></author><author><name sortKey="De Pee, S" uniqKey="De Pee S">S de Pee</name></author><author><name sortKey="Kraemer, K" uniqKey="Kraemer K">K Kraemer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semedo Leite, T" uniqKey="Semedo Leite T">T Semedo Leite</name></author><author><name sortKey="De, Cad" uniqKey="De C">CAD De</name></author><author><name sortKey="Viana, J" uniqKey="Viana J">J Viana</name></author><author><name sortKey="Nogueira, R" uniqKey="Nogueira R">R Nogueira</name></author><author><name sortKey="Lobo, I" uniqKey="Lobo I">I Lobo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Semmelweis, I" uniqKey="Semmelweis I">I Semmelweis</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Seydel, L" uniqKey="Seydel L">L Seydel</name></author><author><name sortKey="Petelski, A" uniqKey="Petelski A">A Petelski</name></author><author><name sortKey="Van Dam, G" uniqKey="Van Dam G">G van Dam</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shirangi, A" uniqKey="Shirangi A">A Shirangi</name></author><author><name sortKey="Nieuwenhuijsen, M" uniqKey="Nieuwenhuijsen M">M Nieuwenhuijsen</name></author><author><name sortKey="Vienneau, D" uniqKey="Vienneau D">D Vienneau</name></author><author><name sortKey="Holman, Cd" uniqKey="Holman C">CD Holman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shulman, C" uniqKey="Shulman C">C Shulman</name></author><author><name sortKey="Dorman, E" uniqKey="Dorman E">E Dorman</name></author><author><name sortKey="Bulmer, J" uniqKey="Bulmer J">J Bulmer</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Siegrist, D" uniqKey="Siegrist D">D Siegrist</name></author><author><name sortKey="Siegrist Obimpeh, P" uniqKey="Siegrist Obimpeh P">P Siegrist-Obimpeh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Singh, J" uniqKey="Singh J">J Singh</name></author><author><name sortKey="Bhoi, S" uniqKey="Bhoi S">S Bhoi</name></author><author><name sortKey="Gupta, V" uniqKey="Gupta V">V Gupta</name></author><author><name sortKey="Goel, A" uniqKey="Goel A">A Goel</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Smith, Jl" uniqKey="Smith J">JL Smith</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Song, T" uniqKey="Song T">T Song</name></author><author><name sortKey="Cho, H" uniqKey="Cho H">H Cho</name></author><author><name sortKey="Kim, J" uniqKey="Kim J">J Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Southwick, Fs" uniqKey="Southwick F">FS Southwick</name></author><author><name sortKey="Purich, Dl" uniqKey="Purich D">DL Purich</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steketee, Rw" uniqKey="Steketee R">RW Steketee</name></author><author><name sortKey="Nahlen, Bl" uniqKey="Nahlen B">BL Nahlen</name></author><author><name sortKey="Parise, Me" uniqKey="Parise M">ME Parise</name></author><author><name sortKey="Menendez, C" uniqKey="Menendez C">C Menendez</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Susser, M" uniqKey="Susser M">M Susser</name></author><author><name sortKey="Susser, E" uniqKey="Susser E">E Susser</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swai, B" uniqKey="Swai B">B Swai</name></author><author><name sortKey="Poggensee, G" uniqKey="Poggensee G">G Poggensee</name></author><author><name sortKey="Mtweve, S" uniqKey="Mtweve S">S Mtweve</name></author><author><name sortKey="Krantz, I" uniqKey="Krantz I">I Krantz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tan, P" uniqKey="Tan P">P Tan</name></author><author><name sortKey="Soe, M" uniqKey="Soe M">M Soe</name></author><author><name sortKey="Si Lay, K" uniqKey="Si Lay K">K Si Lay</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thaddeus, S" uniqKey="Thaddeus S">S Thaddeus</name></author><author><name sortKey="Maine, D" uniqKey="Maine D">D Maine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thatrimontrichai, A" uniqKey="Thatrimontrichai A">A Thatrimontrichai</name></author><author><name sortKey="Maneenil, G" uniqKey="Maneenil G">G Maneenil</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Tsvieli, O" uniqKey="Tsvieli O">O Tsvieli</name></author><author><name sortKey="Sergienko, R" uniqKey="Sergienko R">R Sergienko</name></author><author><name sortKey="Sheiner, E" uniqKey="Sheiner E">E Sheiner</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Vahter, M" uniqKey="Vahter M">M Vahter</name></author><author><name sortKey="Berglund, M" uniqKey="Berglund M">M Berglund</name></author><author><name sortKey=" Kesson, A" uniqKey=" Kesson A">A Åkesson</name></author><author><name sortKey="Liden, C" uniqKey="Liden C">C Lidén</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Eijk, A" uniqKey="Van Eijk A">A van Eijk</name></author><author><name sortKey="Ayisi, J" uniqKey="Ayisi J">J Ayisi</name></author><author><name sortKey="Ter Kuile, F" uniqKey="Ter Kuile F">F ter Kuile</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Velleman, Y" uniqKey="Velleman Y">Y Velleman</name></author><author><name sortKey="Mason, E" uniqKey="Mason E">E Mason</name></author><author><name sortKey="Graham, W" uniqKey="Graham W">W Graham</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Waage, J" uniqKey="Waage J">J Waage</name></author><author><name sortKey="Banerji, R" uniqKey="Banerji R">R Banerji</name></author><author><name sortKey="Campbell, O" uniqKey="Campbell O">O Campbell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wagner, E" uniqKey="Wagner E">E Wagner</name></author><author><name sortKey="Lanoix, J" uniqKey="Lanoix J">J Lanoix</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Waller, K" uniqKey="Waller K">K Waller</name></author><author><name sortKey="Swan, S" uniqKey="Swan S">S Swan</name></author><author><name sortKey="Delorenze, G" uniqKey="Delorenze G">G DeLorenze</name></author><author><name sortKey="Hopkins, B" uniqKey="Hopkins B">B Hopkins</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wasserheit, J" uniqKey="Wasserheit J">J Wasserheit</name></author><author><name sortKey="Harris, J" uniqKey="Harris J">J Harris</name></author><author><name sortKey="Chakraborty, J" uniqKey="Chakraborty J">J Chakraborty</name></author><author><name sortKey="Kay, B" uniqKey="Kay B">B Kay</name></author><author><name sortKey="Mason, K" uniqKey="Mason K">K Mason</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Watts, C" uniqKey="Watts C">C Watts</name></author><author><name sortKey="Cairncross, S" uniqKey="Cairncross S">S Cairncross</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Weisman, C" uniqKey="Weisman C">C Weisman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Whincup, P" uniqKey="Whincup P">P Whincup</name></author><author><name sortKey="Kaye, S" uniqKey="Kaye S">S Kaye</name></author><author><name sortKey="Owen, C" uniqKey="Owen C">C Owen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="White, G" uniqKey="White G">G White</name></author><author><name sortKey="Bradley, D" uniqKey="Bradley D">D Bradley</name></author><author><name sortKey="White, A" uniqKey="White A">A White</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, X" uniqKey="Xiong X">X Xiong</name></author><author><name sortKey="Buekens, P" uniqKey="Buekens P">P Buekens</name></author><author><name sortKey="Fraser, Wd" uniqKey="Fraser W">WD Fraser</name></author><author><name sortKey="Beck, J" uniqKey="Beck J">J Beck</name></author><author><name sortKey="Offenbacher, S" uniqKey="Offenbacher S">S Offenbacher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yermachenko, A" uniqKey="Yermachenko A">A Yermachenko</name></author><author><name sortKey="Dvornyk, V" uniqKey="Dvornyk V">V Dvornyk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Younis, N" uniqKey="Younis N">N Younis</name></author><author><name sortKey="Khattab, H" uniqKey="Khattab H">H Khattab</name></author><author><name sortKey="Zurayk, H" uniqKey="Zurayk H">H Zurayk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ziegelbauer, K" uniqKey="Ziegelbauer K">K Ziegelbauer</name></author><author><name sortKey="Speich, B" uniqKey="Speich B">B Speich</name></author><author><name sortKey="M Usezahl, D" uniqKey="M Usezahl D">D Mäusezahl</name></author></analytic></biblStruct></listBibl></div1></back></TEI><pmc article-type="research-article"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Trop Med Int Health</journal-id><journal-id journal-id-type="iso-abbrev">Trop. Med. Int. Health</journal-id><journal-id journal-id-type="publisher-id">tmi</journal-id><journal-title-group><journal-title>Tropical Medicine & International Health</journal-title></journal-title-group><issn pub-type="ppub">1360-2276</issn><issn pub-type="epub">1365-3156</issn><publisher><publisher-name>Blackwell Publishing Ltd</publisher-name><publisher-loc>Oxford, UK</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">25430609</article-id><article-id pub-id-type="pmc">4681319</article-id><article-id pub-id-type="doi">10.1111/tmi.12439</article-id><article-categories><subj-group subj-group-type="heading"><subject>Women's Health</subject></subj-group></article-categories><title-group><article-title>Getting the basic rights – the role of water, sanitation and hygiene in maternal and reproductive health: a conceptual framework</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Campbell</surname><given-names>Oona M R</given-names></name><xref ref-type="aff" rid="au1">1</xref></contrib><contrib contrib-type="author"><name><surname>Benova</surname><given-names>Lenka</given-names></name><xref ref-type="aff" rid="au1">1</xref></contrib><contrib contrib-type="author"><name><surname>Gon</surname><given-names>Giorgia</given-names></name><xref ref-type="aff" rid="au1">1</xref></contrib><contrib contrib-type="author"><name><surname>Afsana</surname><given-names>Kaosar</given-names></name><xref ref-type="aff" rid="au2">2</xref></contrib><contrib contrib-type="author"><name><surname>Cumming</surname><given-names>Oliver</given-names></name><xref ref-type="aff" rid="au3">3</xref></contrib><aff id="au1"><label>1</label><institution>Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></aff><aff id="au2"><label>2</label><institution>BRAC, Health, Nutrition and Population and BRAC University, James P Grant School of Public Health</institution><addr-line>Dhaka, Bangladesh</addr-line></aff><aff id="au3"><label>3</label><institution>Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine</institution><addr-line>London, UK</addr-line></aff></contrib-group><author-notes><corresp id="cor1"><bold>Corresponding Author Oona M. R. Campbell</bold>, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK. Tel.: +44 (0)20 7927 2210; E-mail: <email>Oona.Campbell@lshtm.ac.uk</email></corresp></author-notes><pub-date pub-type="ppub"><month>3</month><year>2015</year></pub-date><pub-date pub-type="epub"><day>22</day><month>12</month><year>2014</year></pub-date><volume>20</volume><issue>3</issue><fpage>252</fpage><lpage>267</lpage><history><date date-type="accepted"><day>27</day><month>11</month><year>2014</year></date></history><permissions><copyright-statement>© 2014 The Authors. <italic>Tropical Medicine & International Health</italic> Published by John Wiley & Sons Ltd.</copyright-statement><copyright-year>2014</copyright-year><license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/"><license-p>This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.</license-p></license></permissions><abstract><sec><title>Objective</title><p>To explore linkages between water, sanitation and hygiene (WASH) and maternal and perinatal health via a conceptual approach and a scoping review.</p></sec><sec><title>Methods</title><p>We developed a conceptual framework iteratively, amalgamating three literature-based lenses. We then searched literature and identified risk factors potentially linked to maternal and perinatal health. We conducted a systematic scoping review for all chemical and biological WASH risk factors identified using text and MeSH terms, limiting results to systematic reviews or meta-analyses. The remaining 10 complex behavioural associations were not reviewed systematically.</p></sec><sec><title>Results</title><p>The main ways poor WASH could lead to adverse outcomes are via two non-exclusive categories: 1. ‘In-water’ associations: (a) Inorganic contaminants, and (b) ‘water-system’ related infections, (c) ‘water-based’ infections, and (d) ‘water borne’ infections. 2. ‘Behaviour’ associations: (e) Behaviours leading to water-washed infections, (f) Water-related insect-vector infections, and (g-i) Behaviours leading to non-infectious diseases/conditions. We added a gender inequality and a life course lens to the above framework to identify whether WASH affected health of mothers in particular, and acted beyond the immediate effects. This framework led us to identifying 77 risk mechanisms (67 chemical or biological factors and 10 complex behavioural factors) linking WASH to maternal and perinatal health outcomes.</p></sec><sec><title>Conclusion</title><p>WASH affects the risk of adverse maternal and perinatal health outcomes; these exposures are multiple and overlapping and may be distant from the immediate health outcome. Much of the evidence is weak, based on observational studies and anecdotal evidence, with relatively few systematic reviews. New systematic reviews are required to assess the quality of existing evidence more rigorously, and primary research is required to investigate the magnitude of effects of particular WASH exposures on specific maternal and perinatal outcomes. Whilst major gaps exist, the evidence strongly suggests that poor WASH influences maternal and reproductive health outcomes to the extent that it should be considered in global and national strategies.</p></sec></abstract><kwd-group><kwd>water</kwd><kwd>sanitation</kwd><kwd>hygiene</kwd><kwd>maternal health</kwd><kwd>reproductive health</kwd><kwd>perinatal health</kwd><kwd>life course</kwd></kwd-group></article-meta></front><body><sec><title>Introduction</title><p>As 2015 draws closer, there is much debate at an international level as to what will follow the Millennium Development Goals (MDGs) (Horton <xref rid="b81" ref-type="bibr">2012</xref>). The unfinished MDG agenda has been discussed and a desire to complete work on current MDGs stated (The United Nations <xref rid="b167" ref-type="bibr">2012</xref>). Yet it has also been argued that the sector-specific goals and targets embodied in the MDGs resulted in missed opportunities in terms of potential implementation synergies (Waage <italic>et al</italic>. <xref rid="b176" ref-type="bibr">2010</xref>). Elsewhere, the limited progress on reducing the ‘equity gap’ under the MDGs has been raised as a major concern (Chopra <italic>et al</italic>. <xref rid="b44" ref-type="bibr">2012</xref>). This article focuses directly on the potential synergies and links between improving maternal, newborn and reproductive health and safe water, sanitation and hygiene (WASH) and proposes a conceptual framework for understanding them.</p><p>The MDG7 target for water and sanitation calls for the ‘halving of the proportion of the population without sustainable access to safe drinking water and basic sanitation’ by 2015 (United Nations General Assembly <xref rid="b172" ref-type="bibr">2000</xref>). The water target was declared as met in 2010, although 780 million people remain without safe water, whilst the sanitation target is seriously off track and unlikely to be met by 2015, with 2.5 billion people still lacking access (UNICEF, WHO <xref rid="b171" ref-type="bibr">2012</xref>). Coverage of these services is lowest in the poorest regions and countries of the world, and most acute among the poorest populations in these settings (UNICEF, WHO <xref rid="b170" ref-type="bibr">2011</xref>). There was no target for hygiene in MDG7, nor it is consistently measured in global or national WASH monitoring systems.</p><p>Assessments of the disease burden associated with poor WASH are dominated by diarrhoeal disease mortality and acute morbidity (Guerrant <italic>et al</italic>. <xref rid="b75" ref-type="bibr">2002</xref>). Whilst diarrhoeal mortality is reducing, it still accounts for 10% of all child deaths (Liu <italic>et al</italic>. <xref rid="b106" ref-type="bibr">2012</xref>) and morbidity has declined only slightly since 1990 (Fischer Walker <italic>et al</italic>. <xref rid="b66" ref-type="bibr">2012</xref>). There is good evidence for the effect of WASH on a range of other health outcomes, including acute respiratory infections (Rabie & Curtis <xref rid="b139" ref-type="bibr">2006</xref>), soil-transmitted helminth infections (Ziegelbauer <italic>et al</italic>. <xref rid="b188" ref-type="bibr">2012</xref>) and diseases associated with chemical contamination of water (Fewtrell <italic>et al</italic>. <xref rid="b63" ref-type="bibr">2005</xref>). Combining multiple health effects, WHO estimates that unsafe WASH is responsible for almost one-tenth of the global disease burden (Prüss-Üstün <italic>et al</italic>. <xref rid="b137" ref-type="bibr">2008</xref>). To date however, we are unaware of any quantification of the effects of poor WASH on maternal and perinatal health.</p><p>Under MDG5, target 5a is ‘to reduce maternal mortality by three-quarters by 2015’ (United Nations General Assembly <xref rid="b172" ref-type="bibr">2000</xref>). Influential frameworks for improving maternal mortality – such as the ‘Three Delays’ (Thaddeus & Maine <xref rid="b165" ref-type="bibr">1994</xref>) and the ‘Continuum of Care’ (Partnership for Maternal Newborn & Child Health <xref rid="b132" ref-type="bibr">2011</xref>) models – focus almost exclusively on improving access to, and the quality of, maternal health services, with little focus on the wider social and environmental determinants. This emphasis on health services recurs for the MDG5b targets, which address contraceptive coverage and antenatal care services.</p><p>In this study, we explore tentative and confirmed linkages between WASH and maternal and perinatal health using scoping review methods and present a conceptual approach for systematically describing these. Our aim is to provide a broad-ranging conceptualisation that may then be used to guide a process of gathering epidemiologic data on the potential impact of the various risk factors on the ill health of mothers and foetuses/newborns. Although beyond the scope of this study, estimating the contribution of these risk factors to ill health at the population level (population attributable fractions) could then form the basis for identifying and harnessing policy, advocacy and programming synergies that will lead to more effective, efficient and equitable investments in both sectors. We end by identifying research gaps, which, if addressed, would strengthen this framework and lead to greater policy coherence and more effective interventions.</p></sec><sec sec-type="methods"><title>Methods</title><p>Miles and Huberman (<xref rid="b116" ref-type="bibr">1994</xref>) state that a conceptual framework ‘lays out the key factors, constructs or variables, and presumes relationships among them’. Methods for developing frameworks vary, but ours was developed iteratively, using our experiential knowledge (including our technical knowledge and research background) and our literature review that included previous related theory and research, and concepts that had been used to represent similar problems (Novak & Canas <xref rid="b130" ref-type="bibr">2008</xref>). The aim of the framework was to classify and organise the concepts and emphasise connections between them. Our conceptual framework amalgamated three main perspectives: a gender-based lens focusing on health inequalities (Kirschstein <xref rid="b91" ref-type="bibr">1991</xref>), the classification of WASH-related health outcomes (White <italic>et al</italic>. <xref rid="b183" ref-type="bibr">1972</xref>) and the longer-term perspective afforded by a life course approach (Kuh <italic>et al</italic>. <xref rid="b96" ref-type="bibr">2003</xref>; Mishra <italic>et al</italic>. <xref rid="b119" ref-type="bibr">2010</xref>). We applied these perspectives to information extracted from an exploratory literature review that, whilst not systematic, included electronic searches of PubMed and Google Scholar among others, and manual searching of references within key articles. We also searched all the ‘mode of transmission’ and ‘susceptibility’ headings in the Control of Communicable Disease Manual, 19th edition (Heymann <xref rid="b80" ref-type="bibr">2008</xref>), to assess whether transmission for each infectious disease was WASH-related and whether women (or pregnant women and their foetuses/newborns) were at particular risk. We ended by further refining the framework in the light of this targeted search. Through these searches, we identified 77 potential factors that we categorised within our framework.</p><p>We followed with a more targeted scoping with the objective of providing an overview of the existing evidence linking the identified 77 exposures to reproductive and maternal health outcomes, whilst recognising evidence gaps (Arksey & O'Malley <xref rid="b10" ref-type="bibr">2005</xref>; Levac <italic>et al</italic>. <xref rid="b103" ref-type="bibr">2010</xref>). We systematically searched Medline and Embase databases, combining text and MeSH terms for maternal and newborn health among humans with text and MeSH terms for identified 67 chemical and biological mechanisms of exposure. We limited the results of each search to references containing text or MeSH terms for systematic reviews or meta-analyses. We placed no limitations on the date of publication or the language of manuscript. All search results were exported to an EndNote database and screened by one co-author (LB or GG). Systematic reviews that considered the association between any aspect of reproductive or maternal health and the presence or prevention of any of the 67 exposures were identified. The remaining ten behavioural exposures are complex phenomena and would require collaboration with experts from fields beyond public health, such as anthropology, economics and sociology to identify target search terms, databases and grey literature. We did not do a systematic scoping review for these exposures as it was beyond our resources. However, we present individual studies and reports linking reproductive and maternal health to these ten exposures. <xref ref-type="supplementary-material" rid="SD1">Webtable S1</xref> presents the complete listing of the 77 identified mechanisms and indicates availability of systematic reviews and other evidence based on our searches. Only the mechanisms for which links (systematic or other) with reproductive and maternal health were identified are presented in <xref ref-type="supplementary-material" rid="SD2">Webtable S2</xref>, along with a brief summary of the findings.</p><p>We first present the lens or framework (gender lens, WASH transmission framework and the life course perspective) and then the evidence to support posited effects.</p></sec><sec sec-type="results"><title>Results</title><sec><title>Gender inequalities</title><p>Much of the debate in recent decades around the need for epidemiological theory has been in relation to understanding and addressing health inequalities (Krieger & Zierler <xref rid="b95" ref-type="bibr">1996</xref>; Susser & Susser <xref rid="b162" ref-type="bibr">1996</xref>). Our first lens is explicitly gender inequality, although we refer to other inequalities such as poverty or urban/rural divides where they have been described.</p><p>Both biology and gendered behaviour contribute to differences in men's and women's health (Kirschstein <xref rid="b91" ref-type="bibr">1991</xref>; Weisman <xref rid="b181" ref-type="bibr">1997</xref>). The National Institutes of Health (NIH) distinguishes women's health as diseases or conditions ‘unique to women or some subgroup of women; more prevalent in women; more serious among women or some subgroup of women; for which the risk factors are different for women or some subgroup of women; and for which the interventions are different for women or some subgroup of women’ (Kirschstein <xref rid="b91" ref-type="bibr">1991</xref>). As most WASH-related diseases or conditions affect both men and women, we used this definition to highlight those particularly relevant to women in general and to mothers more specifically. If pregnant women were not particularly susceptible, exposed, or affected, but their exposure to WASH-related hazards affected the foetus or newborn, we also highlighted such effects (Kourtis <italic>et al</italic>. <xref rid="b94" ref-type="bibr">2014</xref>).</p></sec><sec><title>WASH impacts</title><p>Figure<xref ref-type="fig" rid="fig01">1</xref> summarises the main ways in which water or sanitation or hygiene can plausibly lead to ill health, distress, harmful behaviours or other adverse outcomes, grouped in two main dimensions: (i) ‘in water’ – microorganisms or chemicals in water and (ii) ‘behaviour’ – actions or cultural aspects related to WASH, including aspects relating to the location of the water point or sanitation facility. We sought to understand how WASH affects health in general and where women, pregnant women, foetuses or newborns are particularly affected.</p><fig id="fig01" position="float"><label>Figure 1</label><caption><p>Dimensions, components and examples of health effects in conceptual framework linking water, sanitation and hygiene (WASH) with maternal and reproductive health.</p></caption><graphic xlink:href="tmi0020-0252-f1"></graphic></fig><p>The Figure<xref ref-type="fig" rid="fig01">1</xref> framework builds on the Bradley classification which identified four principal pathways of water-related disease transmission: ‘water-based’, ‘water-borne’, ‘water-washed’ and ‘water-related’ (White <italic>et al</italic>. <xref rid="b183" ref-type="bibr">1972</xref>). The first two categories are grouped in the ‘in-water’ dimension, which also incorporates subsequent adaptations (Kistemann <xref rid="b92" ref-type="bibr">2004</xref>) to allow for aerosol transmission (Bartram <italic>et al</italic>. <xref rid="b18" ref-type="bibr">2007</xref>), chemical contaminants (Dar & Khan <xref rid="b48" ref-type="bibr">2011</xref>) and chemicals deliberately added to maintain water systems or as public health measures (Ashbolt <xref rid="b12" ref-type="bibr">2004</xref>). The third and fourth Bradley categories are grouped under our ‘behaviour’ dimension, combining ‘water-washed’ and ‘water-related’ with three more ‘behaviour’ categories related to the hazards of location, distance and perceptions of availability or stigma. Our categorisation is influenced by Cairncross and Feachem's (<xref rid="b33" ref-type="bibr">1993</xref>) observation that most faecal–oral infections can be water-washed and that behaviours linked to scarce water, poor sanitation and hygiene can affect these (Wagner & Lanoix <xref rid="b177" ref-type="bibr">1958</xref>). The location and nature of water supply also affects water-related insect vector transmission. For example, wastewater stabilisation ponds can increase mosquito breeding sites (Cairncross & Feachem <xref rid="b33" ref-type="bibr">1993</xref>; Mukhtar <italic>et al</italic>. <xref rid="b124" ref-type="bibr">2006</xref>). Below, we give evidence for these associations grouped by the two dimensions of ‘in water’ and ‘behaviour’ in the order shown in Figure<xref ref-type="fig" rid="fig01">1</xref>. <xref ref-type="supplementary-material" rid="SD1">Webtable S1</xref> presents a detailed list of various transmission routes or mechanisms that may potentially affect health or well-being and summarises the availability of evidence of their impact on women, foetuses or newborns (systematic reviews, other evidence or no evidence). We were able to identify evidence of association for 47 of the 77 identified exposure mechanisms and found at least one systematic review for 30 of the 67 mechanisms for which we conducted a search for systematic reviews.</p></sec><sec><title>Pathways linked to agents in water</title><sec><title>Inorganic contaminants</title><p>The ‘in-water’ associations relate to two main areas: (i) inorganic contaminants and (ii) infectious agents. Many settings have high naturally occurring levels of arsenic and fluoride in groundwater. Studies have linked exposure to arsenic in drinking water with higher risks of spontaneous abortion (Milton <italic>et al</italic>. <xref rid="b117" ref-type="bibr">2005</xref>; Rahman <italic>et al</italic>. <xref rid="b140" ref-type="bibr">2007</xref>), stillbirth (Cherry <italic>et al</italic>. <xref rid="b42" ref-type="bibr">2008</xref>) and infant mortality (Rahman <italic>et al</italic>. <xref rid="b141" ref-type="bibr">2010</xref>), and fluoride has been associated with low birthweight (Diouf <italic>et al</italic>. <xref rid="b53" ref-type="bibr">2012</xref>) and skeletal fluorosis (Bo <italic>et al</italic>. <xref rid="b25" ref-type="bibr">2003</xref>). It has been estimated that in the coastal areas of Bangladesh, increasing saline intrusion during the dry season results in people consuming 2.5–8 times the recommended salt intake, potentially leading to hypertensive disorders of pregnancy (HDP) (Khan <italic>et al</italic>. <xref rid="b88" ref-type="bibr">2011</xref>).</p><p>Industrial contaminants, particularly metals, in drinking water raise concerns for pregnant women, with a systematic review showing adverse effects of metal exposure on placental function and foetal development (Caserta <italic>et al</italic>. <xref rid="b39" ref-type="bibr">2013</xref>), as well as neurodevelopment and other effects in children (Pocock <italic>et al</italic>. <xref rid="b134" ref-type="bibr">1994</xref>; Ferris <italic>et al</italic>. <xref rid="b62" ref-type="bibr">2008</xref>). Exposure to mercury, potassium or lead, for example, is associated with spontaneous abortion (Aschengrau <italic>et al</italic>. <xref rid="b11" ref-type="bibr">1989</xref>) and congenital malformations (Vahter <italic>et al</italic>. <xref rid="b173" ref-type="bibr">2002</xref>; Bellinger <xref rid="b19" ref-type="bibr">2005</xref>). Lead is nephrotoxic and can progressively lead to renal failure, gout and hypertension, all risk factors for HDP (Nolan & Shaikh <xref rid="b128" ref-type="bibr">1992</xref>; Ekong <italic>et al</italic>. <xref rid="b55" ref-type="bibr">2006</xref>). Prenatal exposure resulting in maternal blood lead levels of >10 <italic>μ</italic>g/dl can adversely affect fertility, hypertension, infant neurodevelopment and foetal growth (Bellinger <xref rid="b19" ref-type="bibr">2005</xref>).</p><p>Systematic reviews of exposure to agricultural pesticides and herbicides – that may be consumed via contaminated surface or groundwater – have shown that whilst there is inconclusive evidence for an association between residential proximity to agricultural pesticides and adverse pregnancy outcomes (Shirangi <italic>et al</italic>. <xref rid="b154" ref-type="bibr">2011</xref>), systematic reviews of parental exposure to specific pesticides show these to be associated with specific cancers and other adverse outcomes among children (Lopez Duenas <italic>et al</italic>. <xref rid="b107" ref-type="bibr">2012</xref>; Nicolle-Mir <xref rid="b127" ref-type="bibr">2012</xref>). Some studies have shown that pregnant women and their foetuses are particularly susceptible to effects of nitrates (Calderon <xref rid="b37" ref-type="bibr">2000</xref>), including spontaneous abortions, intrauterine growth restriction, congenital malformations and methaemoglobinaemia (blue baby syndrome), although a systematic review suggests these links are inconclusive (Manassaram <italic>et al</italic>. <xref rid="b111" ref-type="bibr">2006</xref>). Endocrine-disrupting compounds mimic and/or block effects of endogenous hormones and have been associated with earlier age at menarche in a systematic review (Yermachenko & Dvornyk <xref rid="b186" ref-type="bibr">2013</xref>). Early age at menarche is associated with earlier age at first sex, and earlier pregnancy, which in turn, is associated with worse pregnancy outcomes. Endocrine disrupters have also been linked to altered ovarian function, impaired fertility and changed placental function (Balabanič <italic>et al</italic>. <xref rid="b13" ref-type="bibr">2011</xref>; Buttke <italic>et al</italic>. <xref rid="b30" ref-type="bibr">2012</xref>; Fowler <italic>et al</italic>. <xref rid="b68" ref-type="bibr">2012</xref>) and to a higher risk of spontaneous abortions and low birthweight (Calderon <xref rid="b37" ref-type="bibr">2000</xref>; Balabanič <italic>et al</italic>. <xref rid="b13" ref-type="bibr">2011</xref>), although systematic review results of these are inconclusive (Peters <italic>et al</italic>. <xref rid="b133" ref-type="bibr">2010</xref>; Caserta <italic>et al</italic>. <xref rid="b38" ref-type="bibr">2011</xref>). It is generally agreed that disinfection by-products may potentially cause spontaneous abortions (Waller <italic>et al</italic>. <xref rid="b178" ref-type="bibr">1998</xref>), stillbirths (King <italic>et al</italic>. <xref rid="b89" ref-type="bibr">2000</xref>), birth defects (Cedergren <italic>et al</italic>. <xref rid="b40" ref-type="bibr">2002</xref>) and small-for-gestational-age infants (Grellier <italic>et al</italic>. <xref rid="b74" ref-type="bibr">2010</xref>). Some of these associations are supported by systematic reviews.</p></sec><sec><title>Water-system-related infections</title><p>The second subgroup within the ‘in-water’ dimension concerns infectious agents in the water, grouped in the additional ‘water-systems’ category and Bradley's ‘water-based’ and ‘water-borne’ categories (Categories C and D in Figure<xref ref-type="fig" rid="fig01">1</xref>). Whilst water systems can spread infection via poorly maintained air-cooling systems and cause Legionnaires’ disease, this is uncommon and affects the general population without posing particular risks to women (Heymann <xref rid="b80" ref-type="bibr">2008</xref>), so are not considered here, although the category is included in Figure<xref ref-type="fig" rid="fig01">1</xref> for completeness.</p></sec><sec><title>Water-based infections</title><p>Water-based infections are transmitted via aquatic vectors, such as snails, fish or crustaceans, in which part of the life cycle of the infective agent occurs. Schistosomiasis is notable from a maternal/reproductive health perspective as genital schistosomiasis is associated with cervical cancer (Feldmeier <italic>et al</italic>. <xref rid="b61" ref-type="bibr">1995</xref>; Moubayed <italic>et al</italic>. <xref rid="b123" ref-type="bibr">1995</xref>), ectopic pregnancy and infertility (Swai <italic>et al</italic>. <xref rid="b163" ref-type="bibr">2006</xref>); and in pregnant women, it is associated with anaemia (Abdelgadir <italic>et al</italic>. <xref rid="b1" ref-type="bibr">2012</xref>), undernutrition (King <italic>et al</italic>. <xref rid="b90" ref-type="bibr">2005</xref>) and inflammation (Kurtis <italic>et al</italic>. <xref rid="b97" ref-type="bibr">2011</xref>). It can also affect foetal immune response (Seydel <italic>et al</italic>. <xref rid="b153" ref-type="bibr">2012</xref>), leading to foetal inflammation (Kurtis <italic>et al</italic>. <xref rid="b97" ref-type="bibr">2011</xref>) and low birthweight (Siegrist & Siegrist-Obimpeh <xref rid="b156" ref-type="bibr">1992</xref>; Qunhua <italic>et al</italic>. <xref rid="b138" ref-type="bibr">2000</xref>). However, there are no systematic reviews. Other water-based infections, such as dracunculiasis (guinea worm) or diphyllobothriasis (tapeworm), are not known to pose specific risks to women, although pregnant or lactating women may be excluded from treatments if drugs had not been tested in pregnant women and are thus contraindicated (Gyapong <italic>et al</italic>. <xref rid="b77" ref-type="bibr">2003</xref>). Exclusion from treatment because of pregnancy or breastfeeding applies also to other WASH-related diseases and conditions (Maduka <italic>et al</italic>. <xref rid="b108" ref-type="bibr">2004</xref>).</p></sec><sec><title>Water-borne infections</title><p>Water-borne infections are directly transmitted by micro-organisms in water, the classic example being cholera. Here, we consider those that differentially affect women, such as Hepatitis E, with higher incidence, greater severity of symptoms and elevated mortality rates among pregnant women (Emerson & Purcell <xref rid="b57" ref-type="bibr">2004</xref>; Heymann <xref rid="b80" ref-type="bibr">2008</xref>; Aggarwal & Naik <xref rid="b5" ref-type="bibr">2009</xref>). It is also associated with a greater risk of stillbirth (Rein <italic>et al</italic>. <xref rid="b143" ref-type="bibr">2012</xref>).</p></sec></sec><sec><title>Pathways linked to behaviour</title><p>Most water-borne infections are faecal–oral and overlap with the water-washed category and so are captured in the second dimension of ‘behaviour’. This dimension concerns the health effects posed by behaviour relating to WASH. Cairncross and Feachem's redefinition of the water-washed category included infections spread by behaviours stemming from a lack of water or from poor hygiene, including personal and domestic hygiene, and hygiene in the public domain such as in educational establishments and workplaces, including health facilities (Cairncross <italic>et al</italic>. <xref rid="b36" ref-type="bibr">1996</xref>).</p><sec><title>Water-washed infections</title><p>There are many examples of water-washed infections. Evidence in this area can be dated at least as far back as the elegant work of Gordon (<xref rid="b73" ref-type="bibr">1795</xref>) and Semmelweis (<xref rid="b152" ref-type="bibr">1983</xref>) demonstrating the association between puerperal sepsis and poor hygiene of birth attendants, a theory later strengthened by the discovery that the causal agent was Streptococcus A, a water-washed infection. Sepsis in pregnancy or the puerperium is mainly caused by unhygienic practices and poor infection control, including lack of hand-washing, unclean surfaces and unhygienic vaginal examination or cord-cutting in health facilities or in the home (Ali <italic>et al</italic>. <xref rid="b7" ref-type="bibr">2006</xref>; Darmstadt <italic>et al</italic>. <xref rid="b49" ref-type="bibr">2009</xref>). Tetanus is another important contributor to mortality of mothers and newborns, and tetanus toxoid vaccination among pregnant women reduces neonatal death and morbidity (Fauveau <italic>et al</italic>. <xref rid="b60" ref-type="bibr">1993</xref>; Demicheli <italic>et al</italic>. <xref rid="b51" ref-type="bibr">2005</xref>; Roper <italic>et al</italic>. <xref rid="b145" ref-type="bibr">2007</xref>; Kourtis <italic>et al</italic>. <xref rid="b94" ref-type="bibr">2014</xref>). Staphylococcus can be another common cause of puerperal or newborn infection (Heymann <xref rid="b80" ref-type="bibr">2008</xref>).</p><p>Some intestinal worm infections can also be classified as water-washed. An estimated 6.9 million pregnant women in sub-Saharan Africa are infected with hookworm, and systematic reviews show they are at risk of hookworm-related anaemia (Brooker <italic>et al</italic>. <xref rid="b28" ref-type="bibr">2008</xref>). Hookworm infestation in pregnancy is associated with decreased infant birthweight and intrauterine growth retardation (Christian <italic>et al</italic>. <xref rid="b45" ref-type="bibr">2004</xref>), and a systematic review indicated that maternal antihelminthic treatment reduced stillbirths (Menezes <italic>et al</italic>. <xref rid="b115" ref-type="bibr">2009</xref>). Systematic reviews of ascariasis and trichuriasis showed them to be associated with maternal anaemia (Noronha <italic>et al</italic>. <xref rid="b129" ref-type="bibr">2012</xref>) and with stunting and cognitive deficits, respectively (Ruma <italic>et al</italic>. <xref rid="b148" ref-type="bibr">2008</xref>). Helminth infections are also associated with increased susceptibility to HIV/AIDS, malaria and tuberculosis (Fincham <italic>et al</italic>. <xref rid="b65" ref-type="bibr">2003</xref>; Le Hesran <italic>et al</italic>. <xref rid="b100" ref-type="bibr">2004</xref>; Elias <italic>et al</italic>. <xref rid="b56" ref-type="bibr">2007</xref>).</p><p>Systematic reviews indicated that the most common non-malaria bloodstream infection among pregnant women admitted to hospital in reviews of studies from both Africa (Reddy <italic>et al</italic>. <xref rid="b142" ref-type="bibr">2010</xref>) and Asia (Deen <italic>et al</italic>. <xref rid="b50" ref-type="bibr">2012</xref>) is <italic>Salmonella enterica</italic>, to which pregnant women have greater susceptibility (Smith <xref rid="b158" ref-type="bibr">1999</xref>). <italic>Salmonella</italic> can result in spontaneous abortion (Smith <xref rid="b158" ref-type="bibr">1999</xref>). Listeria, another water-borne/water-washed infection, has an annual infection rate over 17 times higher among pregnant women (Southwick & Purich <xref rid="b160" ref-type="bibr">1996</xref>), who account for 27% of all listerial infections (Janakiraman <xref rid="b85" ref-type="bibr">2008</xref>). Exposure in pregnancy is associated with spontaneous abortion (Heymann <xref rid="b80" ref-type="bibr">2008</xref>), stillbirth and preterm delivery (Goldenberg & Thompson <xref rid="b71" ref-type="bibr">2003</xref>). The latter association is confirmed in systematic reviews (Lamont <italic>et al</italic>. <xref rid="b98" ref-type="bibr">2011</xref>; Semedo Leite <italic>et al</italic>. <xref rid="b151" ref-type="bibr">2012</xref>). A systematic review of neonatal melioidosis suggested that vertical transmission exists (Thatrimontrichai & Maneenil <xref rid="b166" ref-type="bibr">2012</xref>), whilst a systematic review of Yersinia infection showed it to be associated with adverse pregnancy outcomes (Semedo Leite <italic>et al</italic>. <xref rid="b151" ref-type="bibr">2012</xref>). The only study found by a systematic review of antenatal genital tract screening and treatment for lower genital tract infection (GTI) showed a reduced risk of preterm birth and preterm low birthweight (Xiong <italic>et al</italic>. <xref rid="b185" ref-type="bibr">2006</xref>). Pregnant women face increased susceptibility to influenza, with increased severity of illness (Jamieson <italic>et al</italic>. <xref rid="b84" ref-type="bibr">2006</xref>). A systematic review showed higherates of hospitalisation, ICU admission and death among pregnant women during the 2009 A(H1N1) flu pandemic (Mosby <italic>et al</italic>. <xref rid="b121" ref-type="bibr">2011</xref>).</p></sec><sec><title>Water-related insect vector-borne infections</title><p>Numerous water-related insect vector infections are transmitted via mosquitoes (malaria, dengue, lymphatic filariasis and yellow fever), tsetse flies (trypanosomiasis) and black flies (onchocerciasis) that live or bite near water. Some of these, namely malaria and dengue, pose specific risks related to women. Pregnant and post-partum women, particularly primi- and secundi-gravidae, are more susceptible to malaria (Boel <italic>et al</italic>. <xref rid="b26" ref-type="bibr">2012</xref>; Chico <italic>et al</italic>. <xref rid="b43" ref-type="bibr">2012</xref>), whereas more subclinical presentation obscures detection and treatment (Desai <italic>et al</italic>. <xref rid="b52" ref-type="bibr">2007</xref>). Malaria in pregnant women is associated with an increased risk of anaemia and severe anaemia (Shulman <italic>et al</italic>. <xref rid="b155" ref-type="bibr">2002</xref>). An estimated 0.5–23.0% of maternal deaths in high transmission areas and 0.6–12.5% in low transmission areas are caused by malaria (Brabin & Verhoeff <xref rid="b27" ref-type="bibr">2002</xref>). Infection with malaria also increases risk of spontaneous abortion (McGready <italic>et al</italic>. <xref rid="b114" ref-type="bibr">2012</xref>), stillbirth (Goldenberg & Thompson <xref rid="b71" ref-type="bibr">2003</xref>) and intrauterine growth retardation (Steketee <italic>et al</italic>. <xref rid="b161" ref-type="bibr">2001</xref>) and leads to anaemia in newborns (van Eijk <italic>et al</italic>. <xref rid="b174" ref-type="bibr">2002</xref>). Systematic reviews of malaria prevention show significant reductions in severe maternal anaemia, low birthweight, perinatal mortality (Desai <italic>et al</italic>. <xref rid="b52" ref-type="bibr">2007</xref>) and stillbirth (Menezes <italic>et al</italic>. <xref rid="b115" ref-type="bibr">2009</xref>; Barros <italic>et al</italic>. <xref rid="b16" ref-type="bibr">2010</xref>; Ishaque <italic>et al</italic>. <xref rid="b83" ref-type="bibr">2011</xref>). Mosquitoes that transmit dengue breed in water-storage containers. General symptoms include internal bleeding, shock and death, but in pregnant women, dengue has been associated with higher maternal mortality (Mota <italic>et al</italic>. <xref rid="b122" ref-type="bibr">2012</xref>) and spontaneous abortion (Tan <italic>et al</italic>. <xref rid="b164" ref-type="bibr">2012</xref>). A systematic review showed conclusive evidence of dengue vertical transmission but inconclusive evidence on adverse pregnancy outcomes (Pouliot <italic>et al</italic>. <xref rid="b136" ref-type="bibr">2010</xref>). Another systematic review showed evidence of vertical transmission of trypanosomiasis, although the absolute risk is unknown (Lindner & Priotto <xref rid="b105" ref-type="bibr">2010</xref>).</p></sec><sec><title>Distant water sources or lack of water when needed</title><p>The ‘behaviour’ dimension also includes WASH-related behaviours that lead to non-infectious diseases or conditions. These include physical aspects of carrying heavy water loads or disposing of faeces, time or money spent on these activities, risks associated with the location of water or sanitation points, and behaviours related to the actual or perceived availability of WASH or to the real or perceived risk of stigma/disgust around the biological processes of defecation, urination or menstruation.</p><p>Data from households in 45 countries show two-thirds of drinking water is collected by women (UNICEF, WHO <xref rid="b170" ref-type="bibr">2011</xref>). Carrying heavy loads is associated with spinal compression, injuries to the spinal column and increased risks of degenerative rheumatism (Dufaut <xref rid="b54" ref-type="bibr">1988</xref>). It can also cause hernia and genital prolapse (Jorgensen <italic>et al</italic>. <xref rid="b87" ref-type="bibr">1994</xref>) and may increase the risk of spontaneous abortion (Florack <italic>et al</italic>. <xref rid="b67" ref-type="bibr">1993</xref>; Figà-Talamanca <xref rid="b64" ref-type="bibr">2006</xref>). Sub-Saharan African studies estimated that an average of 10% of the carrier's daily calorie intake was spent carrying water (Rosen & Vincent <xref rid="b146" ref-type="bibr">1999</xref>). Handling child faeces and socialising children into using sanitation facilities can also expose individuals to risk; women and girls are much more likely to perform these roles (Hannan & Andersson <xref rid="b78" ref-type="bibr">2002</xref>; Gil <italic>et al</italic>. <xref rid="b70" ref-type="bibr">2004</xref>).</p><p>The financial and opportunity costs of obtaining and treating water, doing laundry, managing menstruation and treating WASH-related illnesses can consume a significant share of poor families’ resources. In Africa, it is estimated that water collection accounts for 40 billion hours a year, and the potential reduction in time-lost, poverty and drudgery through better access to water is substantial (Bardasi & Wodon <xref rid="b14" ref-type="bibr">2006</xref>; Lawson <xref rid="b99" ref-type="bibr">2007</xref>). In Pakistan, greater distances from water sources led to reduced participation in income-generating activities for women (Ilahi & Grimard <xref rid="b82" ref-type="bibr">2000</xref>). Households often pay unofficial suppliers of water (often of substandard quality) (Semba <italic>et al</italic>. <xref rid="b150" ref-type="bibr">2009</xref>), and prices charged are typically >10 times the formal water supply tariff (Cairncross & Kinnear <xref rid="b34" ref-type="bibr">1992</xref>). Studies show that reduction in time spent on water-related chores translates into improved school attendance among girls (Koolwal & van de Walle <xref rid="b93" ref-type="bibr">2010</xref>; Nauges & Strand <xref rid="b126" ref-type="bibr">2011</xref>).</p></sec><sec><title>Water and sanitation in isolated locations</title><p>Distant locations of water and sanitation pose other risks, such as snakebites associated with open defecation in fields (Singh <italic>et al</italic>. <xref rid="b157" ref-type="bibr">2008</xref>), and it is known that flies, mosquitoes and cockroaches are common in humid and dark latrines, posing a nuisance, and an occasional risk of harm to health (Curtis & Minjas <xref rid="b47" ref-type="bibr">1985</xref>). Because women take longer to use sanitation points and pregnant women urinate more frequently, they may be exposed to these risks for longer. Other dangers are men taking advantage of the isolated location of latrines to harass, or sexually assault women (Cairncross <xref rid="b31" ref-type="bibr">2003</xref>) – rape and violence against women on the way to or from public toilets and open defecation sites have been widely reported (Amnesty International <xref rid="b9" ref-type="bibr">2010</xref>; Lennon <xref rid="b101" ref-type="bibr">2011</xref>; Massey <xref rid="b112" ref-type="bibr">2011</xref>).</p></sec><sec><title>Perception of water and sanitation availability</title><p>The actual or perceived absence of WASH can lead individuals to adopt harmful behaviours, such as reductions in water use and food consumption (Cairncross & Cliff <xref rid="b32" ref-type="bibr">1987</xref>; Gadgil <xref rid="b69" ref-type="bibr">1998</xref>) and substitution with alcohol (Mamman <italic>et al</italic>. <xref rid="b110" ref-type="bibr">2002</xref>; Potukuchi & Rao <xref rid="b135" ref-type="bibr">2010</xref>). Optimal hydration is necessary for health and cognitive functioning; fluid restriction and inadequate personal hygiene may lead to GTI or urinary tract infections (UTI) (Bledsoe <italic>et al</italic>. <xref rid="b24" ref-type="bibr">1994</xref>; Nygaard & Linder <xref rid="b131" ref-type="bibr">1997</xref>; Amiri <italic>et al</italic>. <xref rid="b8" ref-type="bibr">2009</xref>), which in turn are associated with preterm birth, low birthweight, pre-eclampsia and anaemia (Lettieri <italic>et al</italic>. <xref rid="b102" ref-type="bibr">1993</xref>; Schieve <italic>et al</italic>. <xref rid="b149" ref-type="bibr">1994</xref>; Conde-Agudelo <italic>et al</italic>. <xref rid="b46" ref-type="bibr">2008</xref>; Mazor-Dray <italic>et al</italic>. <xref rid="b113" ref-type="bibr">2009</xref>; Minassian <italic>et al</italic>. <xref rid="b118" ref-type="bibr">2013</xref>).</p><p>Defecation, menstruation and urination can be associated with stigma and consequently damage self-esteem. These biological processes are considered private, if not shameful, in most societies, and a lack of WASH facilities may result in individuals experiencing fear and significant psychological distress. Inadequate toilet provision, especially in low-income urban areas, leads to women's concerns that they cannot maintain their self-respect and social reputation, poses physical safety risks to themselves and their children, increases financial costs and leads to social stigma for living without adequate services (Amnesty International <xref rid="b9" ref-type="bibr">2010</xref>). Women report feeling pressure to use sanitation facilities only at certain times (Massey <xref rid="b112" ref-type="bibr">2011</xref>). The principal benefits from completed water supply projects were identified as less tension/conflict, improved self-esteem, women's empowerment, women's hygiene (e.g. menstrual), improved school attendance and teachers accepting village postings (Cairncross & Valdmanis <xref rid="b35" ref-type="bibr">2006</xref>).</p><p>Menstrual hygiene and hygiene after delivery to manage lochia require water and clean, private toilets and either reusing cloths that have been adequately cleaned and dried, menstrual cups or using single-use pads. Women feel a strong pressure to hide signs of menstruation and resort to reuse of unhygienic moist menstrual rags. Studies link poor menstrual hygiene to urinary or reproductive tract infections and other illnesses (Wasserheit <italic>et al</italic>. <xref rid="b179" ref-type="bibr">1989</xref>; Younis <italic>et al</italic>. <xref rid="b187" ref-type="bibr">1993</xref>), including toxic shock (Heymann <xref rid="b80" ref-type="bibr">2008</xref>), subsequent pelvis inflammatory disease, infertility and pelvic pain (Ahmed & Yesmin <xref rid="b6" ref-type="bibr">2008</xref>).</p><p>Lastly, the availability of WASH is also important in making education establishments and health facilities acceptable to both employees and users. Improvements in water supply were associated with increased uptake of teaching posts in Ghana (Adugna <italic>et al</italic>. <xref rid="b4" ref-type="bibr">2001</xref>). Many have posited that a lack of sanitation and hygiene contribute to truancy, failing classes, absenteeism and drop out, particularly in the transition from primary to secondary schools (Fakeye & Adegoke <xref rid="b59" ref-type="bibr">1994</xref>; Abioye-Kuteyi <xref rid="b2" ref-type="bibr">2000</xref>; Jones & Finlay <xref rid="b86" ref-type="bibr">2001</xref>), although a systematic review of the evidence on the benefits of same-sex toilets in schools for retention of adolescent girls is inconclusive (Birdthistle <italic>et al</italic>. <xref rid="b23" ref-type="bibr">2011</xref>). Healthcare providers ranked lack of water and sanitation points as important reasons for refusing to accept rural postings (Henderson & Tulloch <xref rid="b79" ref-type="bibr">2008</xref>).</p></sec></sec><sec><title>Life course</title><p>The final lens, that of the life course, examines impacts at these different time points, seeking to understand how effects at one age impact across the lifespan, including via intergenerational influences on foetal development and growth (Ben-Shlomo & Kuh <xref rid="b22" ref-type="bibr">2002</xref>). Adopting the life course approach and adding it to the modified WASH framework and to the lens of gender inequality helps identify whether WASH impacts health beyond its immediate effects and presents longer-term consequences, perhaps at a later life stage or intergenerationally.</p><p>In its simplest form, life course theory allows for an effect at one age to act at a later age. For example, infection with <italic>Escherichia coli</italic> has been associated with pregnancy-related hypertension 5 years after infection (Moist <italic>et al</italic>. <xref rid="b120" ref-type="bibr">2009</xref>). Many WASH-related hazards have intergenerational effects; either because contaminants or infectious agents pass through the placenta and affect the foetus, or because they have systemic effects on the mother, such as fever, an altered immune response including inflammation, low weight gain, absorption into bone or anaemia. The consequences for the foetus include spontaneous abortion and stillbirth, but also malformations, infections, anaemia, preterm birth or low birthweight in the newborn. For example, hookworm infection in young women may lead to anaemia, including in pregnancy, which is associated with low birthweight. Low birthweight in turn is associated with cognitive impairment, learning disability and behavioural problems among children; poor anthropometric status in childhood; higher risk of delivering a low birthweight baby in reproductive age; higher arterial blood pressure, chronic kidney disease, ischaemic cardiomyopathy, stroke, diabetes and respiratory disease in adulthood (Rich-Edwards <italic>et al</italic>. <xref rid="b144" ref-type="bibr">1997</xref>; Barker <italic>et al</italic>. <xref rid="b15" ref-type="bibr">2002</xref>; Whincup <italic>et al</italic>. <xref rid="b182" ref-type="bibr">2008</xref>).</p><p>Many risks resulting from disadvantage or poor WASH accumulate. Gender discrimination against girls and women, in terms of access to food, care, education and work, begins in infancy and can determine later life outcomes. Chronic and recurring hookworm infection throughout childbearing age, when women are menstruating, can have a chronic effect on women's iron levels, with iron-deficiency anaemia being especially common in adolescent girls and women of childbearing age (Brooker <italic>et al</italic>. <xref rid="b28" ref-type="bibr">2008</xref>). Hookworm and schistosoma infections are associated with increased incidence of malaria (Adegnika & Kremsner <xref rid="b3" ref-type="bibr">2012</xref>), and malaria itself can also cause severe anaemia. WASH-related pathogens (especially those causing diarrhoea) lead to reduced food intake and the malabsorption of nutrients causing undernutrition, which makes repeat infections more likely (Brown <xref rid="b29" ref-type="bibr">2003</xref>), by increasing the susceptibility to diarrhoea and severity of diarrhoeal episodes (Lima <italic>et al</italic>. <xref rid="b104" ref-type="bibr">2000</xref>; Checkley <italic>et al</italic>. <xref rid="b41" ref-type="bibr">2008</xref>).</p><p>The critical window within the life course approach is illustrated by the 0–2-year age group. Repeated infection with excreta-related pathogens, including worms, in early life leads to growth faltering and stunting (Guerrant <italic>et al</italic>. <xref rid="b76" ref-type="bibr">2012</xref>). Stunted children have little opportunity to catch up later and grow to be short adults. Short women face an increased risk of cephalo-pelvic disproportion, obstructed labour and death and are more likely to have a Caesarean section and low birthweight infant (Song <italic>et al</italic>. <xref rid="b159" ref-type="bibr">2009</xref>; Tsvieli <italic>et al</italic>. <xref rid="b168" ref-type="bibr">2012</xref>). Repeated Caesarean section increases the likelihood of ruptured uterus and placenta praevia, both of which are risk factors for death (Rossi & D'Addario <xref rid="b147" ref-type="bibr">2008</xref>; Main <italic>et al</italic>. <xref rid="b109" ref-type="bibr">2012</xref>).</p></sec></sec><sec sec-type="discussion"><title>Discussion</title><p>The conceptual approach taken here brings together three requisite components for understanding the potential linkages between WASH and maternal and perinatal health: gendered health effects, WASH-related disease transmission and the longer-run life course risks. The framework suggests that WASH affects the risk of adverse maternal health outcomes but that these exposures are multiple and overlapping and may be distant from the immediate health outcome. Our conceptual framework reflects this by taking a life course approach, allowing for risk accumulation and intergenerational effects combined with an equity or gender lens, then linked to the more traditional classification of diseases by transmission.</p><p>Much of the evidence underpinning this framework is surprisingly weak, based on biological plausibility, observational studies and in some cases anecdotal or circumstantial evidence. We found relatively few systematic reviews addressing these topics. For example, despite numerous advocacy claims, the evidence that lack of school sanitation leads girls to dropout or that poor menstrual hygiene causes reproductive tract infections is almost non-existent. However, where direct evidence exists, it confirms the view that adequate WASH may confer substantial benefits to maternal health. Further strengthening of this evidence base is critical and the conceptual framework presented here offers a basis for identifying major research gaps. In particular, systematic reviews are required to more rigorously assess the current quality of evidence for the various exposure/outcome relationships included. Primary research is required to investigate the nature and magnitude of effects for particular WASH exposures (such as improved hygiene practice in birth settings, sustained and heavy water collection and unsanitary menstrual cloths) on specific maternal and reproductive as well as neonatal and child health outcomes.</p><p>Additional work is also required to quantify the population-level impact (population attributable fraction) in relation to maternal and reproductive health outcomes across different settings to assess where WASH may have greater or lesser importance. Finally, in the light of the recent publication of the Global Burden of Disease 2010 estimates (Murray <italic>et al</italic>. <xref rid="b125" ref-type="bibr">2012</xref>), risk factor analyses for WASH may need to be expanded for the outcomes, such as and maternal morbidity, not currently included in these reference models which tend to focus primarily on childhood diseases (Ezzati <italic>et al</italic>. <xref rid="b58" ref-type="bibr">2005</xref>). Once these WASH and maternal and reproductive health relationships are quantified, the scope needs to be widened to include these elements in the disease burden and take account of the complex ways in which factors interact and produce a range of direct and indirect risks (Watts & Cairncross <xref rid="b180" ref-type="bibr">2012</xref>).</p><p>Whilst major gaps exist, the evidence is strongly suggestive of poor WASH influencing maternal and perinatal health outcomes to the extent that it should be considered in global strategies and national policy (Benova <italic>et al</italic>. <xref rid="b20" ref-type="bibr">2014a</xref>; Gon <italic>et al</italic>. <xref rid="b72" ref-type="bibr">2014</xref>). Current evidence precludes reliable estimates of the magnitude and potential of any impact, so that the degree of priority against other critical interventions or services – for example births with skilled attendance, emergency obstetric care, female education – is not clear. However, improved WASH is a human right, and a health and development priority in its own right, irrespective of its role in improving maternal and reproductive health. As a cost-effective and proven public health intervention, WASH services should be scaled up as a matter of urgency and the evidence for links to maternal and reproductive health only reinforces this case (Bartram & Cairncross <xref rid="b17" ref-type="bibr">2010</xref>).</p><p>More pertinent here is whether either sector – maternal and reproductive health or WASH – should adjust its approach to harness the potential synergies suggested by the framework. In this area, we feel justified in suggesting options for consideration and discussion by governments, technical experts and civil society. To simplify these recommendations, we consider two domains: home births and facility births. In the case of domestic births, which account for 54% of births in sub-Saharan Africa (UNICEF <xref rid="b169" ref-type="bibr">2012</xref>), joint planning in providing and targeting services would enable better coordination of resources towards reaching those most at risk. Within a broader strategy to have all births taking place in adequately equipped facilities, improving the environmental conditions for pregnancy, delivery and neonatal care for populations with poor access to health facilities is critical, even if this is an interim measure as part of longer-term strategy. Targeting these high-risk populations for improved WASH should also generate other gains for women and girls, via avoidance of all the other potential WASH-related harms. Sufficient routine surveillance and household survey data are available in almost all countries to characterise WASH-related risk of domestic births but this evidence is not jointly owned, used or tracked by the two sectors. Bringing existing data together and creating incentives for coordination will help target efforts towards the areas of greatest need, thereby addressing disparities or inequities (Benova <italic>et al</italic>. <xref rid="b21" ref-type="bibr">2014b</xref>).</p><p>The second domain of WASH in facility birth settings is critical but less well documented. Data, such as the Service Provision Assessment surveys (SPA), World Health Organization Service Availability and Readiness Assessments (SARA) and Averting Maternal Death and Disability EmONC Needs Assessments, are collected in many settings – albeit with variable quality – but are under-utilised by the WASH sector. Although the most recent WHO Global Annual Assessment of Sanitation and Drinking Water (GLAAS) exercise included questions for governments on access to WASH in health facilities, few responded and the findings were not cross-validated with other available survey data (World Health Organization <xref rid="b184" ref-type="bibr">2012</xref>). The Joint Monitoring Programme of the UN which tracks progress on the MDG water and sanitation target does not report data for WASH in health facilities because the MDG target did not include healthcare facilities and because such data are not routinely captured in the surveys and censuses that it uses to develop its reports (UNICEF, WHO <xref rid="b171" ref-type="bibr">2012</xref>). Better collection and use of this data by the WASH sector, incentivised with national and global targets, may enhance efforts to improve WASH in facility birth settings (Velleman <italic>et al</italic>. <xref rid="b175" ref-type="bibr">2014</xref>).</p></sec><sec><title>Conclusion</title><p>There is a body of evidence, supported by biological plausibility, that poor WASH negatively influences maternal and reproductive health outcomes, and foetal and neonatal outcomes, in a multitude of ways. This study presents a framework that builds on and combines existing approaches to identify gender inequalities in health, to classify WASH-related diseases and to delineate a life course approach. We identified a number of systematic reviews reporting associations between WASH and these outcomes that confirm that these linkages are complex and long term, but nonetheless important. Within the conceptual framework presented here, we also elucidate that there are many gaps requiring both primary research to investigate specific exposure–outcome relationships, and additional systematic reviews of existing evidence. Whilst more evidence is needed, this work suggests there is sufficient evidence for greater consideration of WASH in closing the gap on maternal and perinatal health.</p></sec></body><back><ack><p>The authors are particularly grateful to Yael Velleman from WaterAid and Wendy Graham from University of Aberdeen for their thoughtful comments on a draft of the study. This research was made possible with UK Aid from the Department of International Development (DFID) as part of the Sanitation and Hygiene Applied Research for Equity (SHARE) Research Consortium (<ext-link ext-link-type="uri" xlink:href="http://www.SHAREresearch.org">http://www.SHAREresearch.org</ext-link>). However, the views expressed do not necessarily reflect the Department's official policies. Giorgia Gon is funded by The SoapBox Collaborative. The funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.</p></ack><ref-list><title>References</title><ref id="b1"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Abdelgadir</surname><given-names>M</given-names></name><name><surname>Khalid</surname><given-names>A</given-names></name><name><surname>Ashmaig</surname><given-names>A</given-names></name><etal></etal></person-group><article-title>Epidemiology of anaemia among pregnant women in Geizera, central Sudan</article-title><source>Journal of Obstetrics and Gynaecology</source><year>2012</year><volume>32</volume><fpage>42</fpage><lpage>44</lpage><pub-id pub-id-type="pmid">22185535</pub-id></element-citation></ref><ref id="b2"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Abioye-Kuteyi</surname><given-names>E</given-names></name></person-group><article-title>Menstrual knowledge and practices amongst secondary school girls in lle lfe, Nigeria</article-title><source>Perspectives in Public Health</source><year>2000</year><volume>120</volume><fpage>23</fpage><lpage>26</lpage></element-citation></ref><ref id="b3"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Adegnika</surname><given-names>A</given-names></name><name><surname>Kremsner</surname><given-names>P</given-names></name></person-group><article-title>Epidemiology of malaria and helminth interaction: a review from 2001 to 2011</article-title><source>Current Opinion in HIV and AIDS</source><year>2012</year><volume>7</volume><fpage>221</fpage><lpage>224</lpage><pub-id pub-id-type="pmid">22418449</pub-id></element-citation></ref><ref id="b4"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Adugna</surname><given-names>A</given-names></name><name><surname>Dery</surname><given-names>M</given-names></name><name><surname>Gomme</surname><given-names>J</given-names></name><etal></etal></person-group><source>Looking Back: The Long-Term Impacts of Water and Sanitation Projects</source><year>2001</year><publisher-loc>London, UK</publisher-loc><publisher-name>WaterAid</publisher-name></element-citation></ref><ref id="b5"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Aggarwal</surname><given-names>R</given-names></name><name><surname>Naik</surname><given-names>S</given-names></name></person-group><article-title>Epidemiology of hepatitis E: current status</article-title><source>Journal of Gastroenterology and Hepatology</source><year>2009</year><volume>24</volume><fpage>1484</fpage><lpage>1493</lpage><pub-id pub-id-type="pmid">19686410</pub-id></element-citation></ref><ref id="b6"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Ahmed</surname><given-names>R</given-names></name></person-group><person-group person-group-type="editor"><name><surname>Wicken</surname><given-names>J</given-names></name><name><surname>Verhagen</surname><given-names>J</given-names></name><name><surname>Sijbesma</surname><given-names>C</given-names></name><name><surname>Da Silva</surname><given-names>C</given-names></name><name><surname>Ryan</surname><given-names>P</given-names></name><name><surname>Yesmin</surname><given-names>K</given-names></name></person-group><article-title>Menstrual hygiene: breaking the silence</article-title><source>Beyond Construction: Use By All</source><year>2008</year><publisher-loc>London, UK and Delft, the Netherlands</publisher-loc><publisher-name>IRC International Water and Sanitation Centre and WaterAid</publisher-name><fpage>283</fpage><lpage>287</lpage></element-citation></ref><ref id="b7"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ali</surname><given-names>T</given-names></name><name><surname>Fikree</surname><given-names>F</given-names></name><name><surname>Rahbar</surname><given-names>M</given-names></name><name><surname>Mahmud</surname><given-names>S</given-names></name></person-group><article-title>Frequency and determinants of vaginal infection in postpartum period: a crosssectional survey from low socioeconomic settlements, Karachi, Pakistan</article-title><source>Journal of the Pakistan Medical Association</source><year>2006</year><volume>56</volume><fpage>99</fpage><lpage>103</lpage><pub-id pub-id-type="pmid">16696506</pub-id></element-citation></ref><ref id="b8"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Amiri</surname><given-names>FN</given-names></name><name><surname>Rooshan</surname><given-names>MH</given-names></name><name><surname>Ahmady</surname><given-names>MH</given-names></name><name><surname>Soliamani</surname><given-names>MJ</given-names></name></person-group><article-title>Hygiene practices and sexual activity associated with urinary tract infection in pregnant women</article-title><source>Eastern Mediterranean Health Journal</source><year>2009</year><volume>15</volume><fpage>104</fpage><lpage>110</lpage><pub-id pub-id-type="pmid">19469432</pub-id></element-citation></ref><ref id="b9"><element-citation publication-type="book"><collab>Amnesty International</collab><source>Risking Rape to Reach a Toilet. Women's Experiences in the Slums of Nairobi, Kenya</source><year>2010</year><publisher-loc>London, UK</publisher-loc><publisher-name>Amnesty International</publisher-name></element-citation></ref><ref id="b10"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Arksey</surname><given-names>H</given-names></name><name><surname>O'Malley</surname><given-names>L</given-names></name></person-group><article-title>Scoping studies: towards a methodological framework</article-title><source>International Journal of Social Research Methodology</source><year>2005</year><volume>8</volume><fpage>19</fpage><lpage>32</lpage></element-citation></ref><ref id="b11"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Aschengrau</surname><given-names>A</given-names></name><name><surname>Zierler</surname><given-names>S</given-names></name><name><surname>Cohen</surname><given-names>A</given-names></name></person-group><article-title>Quality of community drinking water and the occurrence of spontaneous abortion</article-title><source>Archives of Environmental Health: An International Journal</source><year>1989</year><volume>44</volume><fpage>283</fpage><lpage>290</lpage></element-citation></ref><ref id="b12"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ashbolt</surname><given-names>N</given-names></name></person-group><article-title>Microbial contamination of drinking water and disease outcomes in developing regions</article-title><source>Toxicology</source><year>2004</year><volume>198</volume><fpage>229</fpage><lpage>238</lpage><pub-id pub-id-type="pmid">15138046</pub-id></element-citation></ref><ref id="b13"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Balabanič</surname><given-names>D</given-names></name><name><surname>Rupnik</surname><given-names>M</given-names></name><name><surname>Klemenčič</surname><given-names>A</given-names></name></person-group><article-title>Negative impact of endocrine-disrupting compounds on human reproductive health</article-title><source>Reproduction, Fertility, and Development</source><year>2011</year><volume>23</volume><fpage>403</fpage><lpage>416</lpage></element-citation></ref><ref id="b14"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Bardasi</surname><given-names>E</given-names></name><name><surname>Wodon</surname><given-names>Q</given-names></name></person-group><source>Measuring Time Poverty and Analysing Its Determinants: Concepts and Application to Guinea</source><year>2006</year><publisher-loc>Washington DC</publisher-loc><publisher-name>World Bank</publisher-name></element-citation></ref><ref id="b15"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Barker</surname><given-names>D</given-names></name><name><surname>Forsén</surname><given-names>T</given-names></name><name><surname>Eriksson</surname><given-names>J</given-names></name><name><surname>Osmond</surname><given-names>C</given-names></name></person-group><article-title>Growth and living conditions in childhood and hypertension in adult life: a longitudinal study</article-title><source>Journal of Hypertension</source><year>2002</year><volume>20</volume><fpage>1951</fpage><lpage>1956</lpage><pub-id pub-id-type="pmid">12359972</pub-id></element-citation></ref><ref id="b16"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Barros</surname><given-names>FC</given-names></name><name><surname>Bhutta</surname><given-names>ZA</given-names></name><name><surname>Batra</surname><given-names>M</given-names></name><etal></etal></person-group><article-title>Global report on preterm birth and stillbirth (3 of 7): evidence for effectiveness of interventions</article-title><source>BMC Pregnancy and Childbirth</source><year>2010</year><volume>10</volume><issue>Suppl 1</issue><fpage>S3</fpage><pub-id pub-id-type="pmid">20233384</pub-id></element-citation></ref><ref id="b17"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bartram</surname><given-names>J</given-names></name><name><surname>Cairncross</surname><given-names>S</given-names></name></person-group><article-title>Hygiene, sanitation, and water: forgotten foundations of health</article-title><source>PLoS Medicine</source><year>2010</year><volume>7</volume><fpage>e1000367</fpage><pub-id pub-id-type="pmid">21085694</pub-id></element-citation></ref><ref id="b18"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Bartram</surname><given-names>J</given-names></name><name><surname>Chartier</surname><given-names>Y</given-names></name><name><surname>Lee</surname><given-names>J</given-names></name><name><surname>Pond</surname><given-names>K</given-names></name><name><surname>Surman-Lee</surname><given-names>S</given-names></name></person-group><source>Legionella and the Prevention of Legionellosis</source><year>2007</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="b19"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bellinger</surname><given-names>D</given-names></name></person-group><article-title>Teratogen update: lead and pregnancy</article-title><source>Birth Defects Research. Part A, Clinical and Molecular Teratology</source><year>2005</year><volume>73</volume><fpage>409</fpage><lpage>420</lpage></element-citation></ref><ref id="b20"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Benova</surname><given-names>L</given-names></name><name><surname>Cumming</surname><given-names>O</given-names></name><name><surname>Campbell</surname><given-names>O</given-names></name></person-group><article-title>Systematic review and meta-analysis: association between water and sanitation environment and maternal mortality</article-title><source>Tropical Medicine & International Health</source><year>2014a</year><volume>19</volume><fpage>368</fpage><lpage>387</lpage><pub-id pub-id-type="pmid">24506558</pub-id></element-citation></ref><ref id="b21"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Benova</surname><given-names>L</given-names></name><name><surname>Cumming</surname><given-names>O</given-names></name><name><surname>Gordon</surname><given-names>B</given-names></name><name><surname>Magoma</surname><given-names>M</given-names></name><name><surname>Campbell</surname><given-names>O</given-names></name></person-group><article-title>Where there is no toilet: water and sanitation environments of domestic and facility births in Tanzania</article-title><source>PLoS One</source><year>2014b</year><volume>9</volume><fpage>e106738</fpage><pub-id pub-id-type="pmid">25191753</pub-id></element-citation></ref><ref id="b22"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ben-Shlomo</surname><given-names>Y</given-names></name><name><surname>Kuh</surname><given-names>D</given-names></name></person-group><article-title>A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives</article-title><source>International Journal of Epidemiology</source><year>2002</year><volume>31</volume><fpage>285</fpage><lpage>293</lpage><pub-id pub-id-type="pmid">11980781</pub-id></element-citation></ref><ref id="b23"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Birdthistle</surname><given-names>I</given-names></name><name><surname>Dickson</surname><given-names>K</given-names></name><name><surname>Freeman</surname><given-names>M</given-names></name><name><surname>Javidi</surname><given-names>L</given-names></name></person-group><source>What Impact Does the Provision of Separate Toilets for Girls at School Have on Their Primary and Secondary School Enrolment, Attendance and Completion? A Systematic Review of the Evidence</source><year>2011</year><publisher-loc>London</publisher-loc><publisher-name>MARCH Centre at LSHTM and EPPI-Centre, University of London</publisher-name></element-citation></ref><ref id="b24"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bledsoe</surname><given-names>C</given-names></name><name><surname>Hill</surname><given-names>A</given-names></name><name><surname>Langerock</surname><given-names>P</given-names></name><name><surname>D'Alessandro</surname><given-names>U</given-names></name></person-group><article-title>Constructing natural fertility: the use of western contraceptive technologies in rural Gambia</article-title><source>Population and Development Review</source><year>1994</year><volume>20</volume><fpage>81</fpage><lpage>113</lpage></element-citation></ref><ref id="b25"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Bo</surname><given-names>Z</given-names></name><name><surname>Mei</surname><given-names>H</given-names></name><name><surname>Yongsheng</surname><given-names>Z</given-names></name><etal></etal></person-group><article-title>Distribution and risk assessment of fluoride in drinking water in the west plain region of Jilin province, China</article-title><source>Environmental Geochemistry and Health</source><year>2003</year><volume>25</volume><fpage>421</fpage><lpage>431</lpage><pub-id pub-id-type="pmid">14740986</pub-id></element-citation></ref><ref id="b26"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Boel</surname><given-names>ME</given-names></name><name><surname>Rijken</surname><given-names>MJ</given-names></name><name><surname>Brabin</surname><given-names>BJ</given-names></name><name><surname>Nosten</surname><given-names>F</given-names></name><name><surname>McGready</surname><given-names>R</given-names></name></person-group><article-title>The epidemiology of postpartum malaria: a systematic review</article-title><source>Malaria Journal</source><year>2012</year><volume>11</volume><fpage>114</fpage><comment>doi:<ext-link ext-link-type="doi" xlink:href="10.1186/1475-2875-11-114">10.1186/1475-2875-11-114</ext-link></comment><pub-id pub-id-type="pmid">22500576</pub-id></element-citation></ref><ref id="b27"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Brabin</surname><given-names>B</given-names></name></person-group><person-group person-group-type="editor"><name><surname>Maclean</surname><given-names>A</given-names></name><name><surname>Nielson</surname><given-names>J</given-names></name><name><surname>Verhoeff</surname><given-names>F</given-names></name></person-group><article-title>The contribution of malaria</article-title><source>Maternal Morbidity and Mortality</source><year>2002</year><publisher-loc>London</publisher-loc><publisher-name>Royal College of Obstetricians and Gynaecologists</publisher-name><fpage>65</fpage><lpage>78</lpage></element-citation></ref><ref id="b28"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Brooker</surname><given-names>S</given-names></name><name><surname>Hotez</surname><given-names>PJ</given-names></name><name><surname>Bundy</surname><given-names>DAP</given-names></name></person-group><article-title>Hookworm-related anaemia among pregnant women: a systematic review</article-title><source>PLoS Neglected Tropical Diseases</source><year>2008</year><volume>2</volume><fpage>e291</fpage><pub-id pub-id-type="pmid">18820740</pub-id></element-citation></ref><ref id="b29"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Brown</surname><given-names>K</given-names></name></person-group><article-title>Diarrhea and malnutrition</article-title><source>Journal of Nutrition</source><year>2003</year><volume>133</volume><fpage>328</fpage><lpage>332</lpage></element-citation></ref><ref id="b30"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Buttke</surname><given-names>D</given-names></name><name><surname>Sircar</surname><given-names>K</given-names></name><name><surname>Martin</surname><given-names>C</given-names></name></person-group><article-title>Exposures to endocrine-disrupting chemicals and age of menarche in adolescent girls in NHANES (2003–2008)</article-title><source>Environmental Health Perspectives</source><year>2012</year><volume>120</volume><fpage>1613</fpage><lpage>1618</lpage><pub-id pub-id-type="pmid">23124194</pub-id></element-citation></ref><ref id="b31"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cairncross</surname><given-names>S</given-names></name></person-group><article-title>Sanitation in the developing world: current status and future solutions</article-title><source>International Journal of Environmental Health Research</source><year>2003</year><volume>13</volume><fpage>S123</fpage><lpage>S131</lpage><pub-id pub-id-type="pmid">12775388</pub-id></element-citation></ref><ref id="b32"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cairncross</surname><given-names>S</given-names></name><name><surname>Cliff</surname><given-names>J</given-names></name></person-group><article-title>Water use and health in Mueda, Mozambique</article-title><source>Transactions of the Royal Society of Tropical Medicine and Hygiene</source><year>1987</year><volume>81</volume><fpage>51</fpage><lpage>54</lpage><pub-id pub-id-type="pmid">3445322</pub-id></element-citation></ref><ref id="b33"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Cairncross</surname><given-names>S</given-names></name><name><surname>Feachem</surname><given-names>R</given-names></name></person-group><source>Environmental Health Engineering in the Tropics</source><year>1993</year><publisher-loc>Chichester, UK</publisher-loc><publisher-name>John Wiley & Sons</publisher-name></element-citation></ref><ref id="b34"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cairncross</surname><given-names>S</given-names></name><name><surname>Kinnear</surname><given-names>J</given-names></name></person-group><article-title>Elasticity of demand for water in Khartoum, Sudan</article-title><source>Social Science & Medicine</source><year>1992</year><volume>34</volume><fpage>183</fpage><lpage>189</lpage><pub-id pub-id-type="pmid">1738871</pub-id></element-citation></ref><ref id="b35"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Cairncross</surname><given-names>S</given-names></name><name><surname>Valdmanis</surname><given-names>V</given-names></name></person-group><person-group person-group-type="editor"><name><surname>Jamison</surname><given-names>D</given-names></name><name><surname>Breman</surname><given-names>J</given-names></name><name><surname>Measham</surname><given-names>A</given-names></name><name><surname>Alleyne</surname><given-names>G</given-names></name><etal></etal><name><surname>Claeson</surname><given-names>M</given-names></name></person-group><article-title>Water supply, sanitation, and hygiene promotion</article-title><source>Disease Control Priorities in Developing Countries</source><year>2006</year><edition>2nd edn</edition><publisher-loc>New York</publisher-loc><publisher-name>Oxford University Press</publisher-name><fpage>771</fpage><lpage>792</lpage></element-citation></ref><ref id="b36"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cairncross</surname><given-names>S</given-names></name><name><surname>Blumenthal</surname><given-names>U</given-names></name><name><surname>Kolsky</surname><given-names>P</given-names></name><name><surname>Moraes</surname><given-names>L</given-names></name><name><surname>Tayeh</surname><given-names>A</given-names></name></person-group><article-title>The public and domestic domains in the transmission of disease</article-title><source>Tropical Medicine and International Health</source><year>1996</year><volume>1</volume><fpage>27</fpage><lpage>34</lpage><pub-id pub-id-type="pmid">8673819</pub-id></element-citation></ref><ref id="b37"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Calderon</surname><given-names>R</given-names></name></person-group><article-title>The epidemiology of chemical contaminants of drinking water</article-title><source>Food and Chemical Toxicology</source><year>2000</year><volume>38</volume><fpage>S13</fpage><lpage>S20</lpage><pub-id pub-id-type="pmid">10717366</pub-id></element-citation></ref><ref id="b38"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Caserta</surname><given-names>D</given-names></name><name><surname>Mantovani</surname><given-names>A</given-names></name><name><surname>Marci</surname><given-names>R</given-names></name><etal></etal></person-group><article-title>Environment and women's reproductive health</article-title><source>Human Reproduction Update</source><year>2011</year><volume>17</volume><fpage>418</fpage><lpage>433</lpage><pub-id pub-id-type="pmid">21266373</pub-id></element-citation></ref><ref id="b39"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Caserta</surname><given-names>D</given-names></name><name><surname>Matteucci</surname><given-names>E</given-names></name><name><surname>Ralli</surname><given-names>E</given-names></name><name><surname>Moscarini</surname><given-names>M</given-names></name></person-group><article-title>Heavy metals in amniotic fluid</article-title><source>Journal of Perinatal Medicine</source><year>2013</year><volume>41</volume><fpage>290</fpage><lpage>983</lpage><comment>S1</comment></element-citation></ref><ref id="b40"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cedergren</surname><given-names>M</given-names></name><name><surname>Selbing</surname><given-names>A</given-names></name><name><surname>Lofman</surname><given-names>O</given-names></name><name><surname>Kallen</surname><given-names>B</given-names></name></person-group><article-title>Chlorination byproducts and nitrate in drinking water and risk for congenital cardiac defects</article-title><source>Environmental Research</source><year>2002</year><volume>89</volume><fpage>124</fpage><lpage>130</lpage><pub-id pub-id-type="pmid">12123645</pub-id></element-citation></ref><ref id="b41"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Checkley</surname><given-names>W</given-names></name><name><surname>Buckley</surname><given-names>G</given-names></name><name><surname>Gilman</surname><given-names>R</given-names></name><etal></etal></person-group><article-title>Multi-country analysis of the effects of diarrhoea on childhood stunting</article-title><source>International Journal of Epidemiology</source><year>2008</year><volume>37</volume><fpage>816</fpage><lpage>830</lpage><pub-id pub-id-type="pmid">18567626</pub-id></element-citation></ref><ref id="b42"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Cherry</surname><given-names>N</given-names></name><name><surname>Shaikh</surname><given-names>K</given-names></name><name><surname>McDonald</surname><given-names>C</given-names></name><name><surname>Chowdhury</surname><given-names>Z</given-names></name></person-group><article-title>Stillbirth in rural Bangladesh: arsenic exposure and other etiological factors: a report from Gonoshasthaya Kendra</article-title><source>Bulletin of the World Health Organization</source><year>2008</year><volume>86</volume><fpage>172</fpage><lpage>177</lpage><pub-id pub-id-type="pmid">18368203</pub-id></element-citation></ref><ref id="b43"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Chico</surname><given-names>R</given-names></name><name><surname>Mayaud</surname><given-names>P</given-names></name><name><surname>Ariti</surname><given-names>C</given-names></name><etal></etal></person-group><article-title>Prevalence of malaria and sexually transmitted and reproductive tract infections in pregnancy in sub-Saharan Africa: a systematic review</article-title><source>Journal of the American Medical Association</source><year>2012</year><volume>307</volume><fpage>2079</fpage><lpage>2086</lpage><pub-id pub-id-type="pmid">22665107</pub-id></element-citation></ref><ref id="b44"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Chopra</surname><given-names>M</given-names></name><name><surname>Sharkey</surname><given-names>A</given-names></name><name><surname>Dalmiya</surname><given-names>N</given-names></name><etal></etal></person-group><article-title>Strategies to improve health coverage and narrow the equity gap in child survival, health, and nutrition</article-title><source>The Lancet</source><year>2012</year><volume>380</volume><fpage>1331</fpage><lpage>1340</lpage></element-citation></ref><ref id="b45"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Christian</surname><given-names>P</given-names></name><name><surname>Khatry</surname><given-names>S</given-names></name><name><surname>West</surname><given-names>K</given-names></name></person-group><article-title>Antenatal anthelmintic treatment, birthweight, and infant survival in rural Nepal</article-title><source>Lancet</source><year>2004</year><volume>364</volume><fpage>981</fpage><lpage>983</lpage><pub-id pub-id-type="pmid">15364190</pub-id></element-citation></ref><ref id="b46"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Conde-Agudelo</surname><given-names>A</given-names></name><name><surname>Villar</surname><given-names>J</given-names></name><name><surname>Lindheimer</surname><given-names>M</given-names></name></person-group><article-title>Maternal infection and risk of preeclampsia: systematic review and meta analysis</article-title><source>American Journal of Obstetrics and Gynecology</source><year>2008</year><volume>198</volume><fpage>7</fpage><lpage>22</lpage><pub-id pub-id-type="pmid">18166297</pub-id></element-citation></ref><ref id="b47"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Curtis</surname><given-names>C</given-names></name><name><surname>Minjas</surname><given-names>J</given-names></name></person-group><article-title>Expanded polystyrene for mosquito control</article-title><source>Parasitology Today</source><year>1985</year><volume>1</volume><fpage>36</fpage><pub-id pub-id-type="pmid">15275624</pub-id></element-citation></ref><ref id="b48"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dar</surname><given-names>OA</given-names></name><name><surname>Khan</surname><given-names>MS</given-names></name></person-group><article-title>Millennium Development Goals and the water target: details, definitions and debate</article-title><source>Tropical Medicine and International Health</source><year>2011</year><volume>16</volume><fpage>540</fpage><lpage>544</lpage><pub-id pub-id-type="pmid">21320242</pub-id></element-citation></ref><ref id="b49"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Darmstadt</surname><given-names>G</given-names></name><name><surname>Hasan</surname><given-names>M</given-names></name><name><surname>Balsara</surname><given-names>Z</given-names></name><etal></etal></person-group><article-title>Impact of clean delivery-kit use on newborn umbilical cord and maternal puerperal infections in Egypt</article-title><source>Journal of Health, Population, and Nutrition</source><year>2009</year><volume>27</volume><fpage>746</fpage><lpage>754</lpage></element-citation></ref><ref id="b50"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Deen</surname><given-names>J</given-names></name><name><surname>von Seidlein</surname><given-names>L</given-names></name><name><surname>Andersen</surname><given-names>F</given-names></name><etal></etal></person-group><article-title>Community-acquired bacterial bloodstream infections in developing countries in south and southeast Asia: a systematic review</article-title><source>The Lancet. Infectious Diseases</source><year>2012</year><volume>12</volume><fpage>480</fpage><lpage>487</lpage><pub-id pub-id-type="pmid">22632186</pub-id></element-citation></ref><ref id="b51"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Demicheli</surname><given-names>V</given-names></name><name><surname>Barale</surname><given-names>A</given-names></name><name><surname>Rivetti</surname><given-names>A</given-names></name></person-group><article-title>Vaccines for women to prevent neonatal tetanus</article-title><source>Cochrane Database of Systematic Reviews</source><year>2005</year><fpage>CD002959</fpage><comment>(Online)</comment><pub-id pub-id-type="pmid">16235306</pub-id></element-citation></ref><ref id="b52"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Desai</surname><given-names>M</given-names></name><name><surname>ter Kuile</surname><given-names>F</given-names></name><name><surname>Nosten</surname><given-names>F</given-names></name><etal></etal></person-group><article-title>Epidemiology and burden of malaria in pregnancy</article-title><source>The Lancet. Infectious Diseases</source><year>2007</year><volume>7</volume><fpage>93</fpage><lpage>104</lpage><pub-id pub-id-type="pmid">17251080</pub-id></element-citation></ref><ref id="b53"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Diouf</surname><given-names>M</given-names></name><name><surname>Cisse</surname><given-names>D</given-names></name><name><surname>Lo</surname><given-names>C</given-names></name><etal></etal></person-group><article-title>Pregnant women living in areas of endemic fluorosis in Senegal and low birthweight newborns: case–control study</article-title><source>Revue d'Epidemiologie et de Sante Publique</source><year>2012</year><volume>60</volume><fpage>103</fpage><lpage>108</lpage></element-citation></ref><ref id="b54"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Dufaut</surname><given-names>A</given-names></name></person-group><article-title>Women carrying water: how it affects their health</article-title><source>Waterlines</source><year>1988</year><volume>6</volume><fpage>23</fpage><lpage>25</lpage></element-citation></ref><ref id="b55"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ekong</surname><given-names>E</given-names></name><name><surname>Jaar</surname><given-names>B</given-names></name><name><surname>Weaver</surname><given-names>V</given-names></name></person-group><article-title>Lead-related nephrotoxicity: a review of the epidemiologic evidence</article-title><source>Kidney International</source><year>2006</year><volume>70</volume><fpage>2074</fpage><lpage>2084</lpage><pub-id pub-id-type="pmid">17063179</pub-id></element-citation></ref><ref id="b56"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Elias</surname><given-names>D</given-names></name><name><surname>Britton</surname><given-names>S</given-names></name><name><surname>Kassu</surname><given-names>A</given-names></name><name><surname>Akuffo</surname><given-names>H</given-names></name></person-group><article-title>Chronic helminth infections may negatively influence immunity against tuberculosis and other diseases of public health importance</article-title><source>Expert Review of Antiinfective Therapy</source><year>2007</year><volume>5</volume><fpage>475</fpage><lpage>484</lpage></element-citation></ref><ref id="b57"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Emerson</surname><given-names>SU</given-names></name><name><surname>Purcell</surname><given-names>RH</given-names></name></person-group><article-title>Running like water – the omnipresence of hepatitis E</article-title><source>New England Journal of Medicine</source><year>2004</year><volume>351</volume><fpage>2367</fpage><lpage>2368</lpage><pub-id pub-id-type="pmid">15575050</pub-id></element-citation></ref><ref id="b58"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ezzati</surname><given-names>M</given-names></name><name><surname>Utzinger</surname><given-names>J</given-names></name><name><surname>Cairncross</surname><given-names>S</given-names></name><name><surname>Cohen</surname><given-names>A</given-names></name><name><surname>Singer</surname><given-names>B</given-names></name></person-group><article-title>Environmental risks in the developing world: exposure indicators for evaluating interventions, programmes, and policies</article-title><source>Journal of Epidemiology and Community Health</source><year>2005</year><volume>59</volume><fpage>15</fpage><lpage>22</lpage><pub-id pub-id-type="pmid">15598721</pub-id></element-citation></ref><ref id="b59"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fakeye</surname><given-names>O</given-names></name><name><surname>Adegoke</surname><given-names>A</given-names></name></person-group><article-title>The characteristics of the menstrual cycle in Nigerian school girls and the implications for school health programs</article-title><source>African Journal of Medicine and Medical Sciences</source><year>1994</year><volume>23</volume><fpage>13</fpage><lpage>17</lpage><pub-id pub-id-type="pmid">7839939</pub-id></element-citation></ref><ref id="b60"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fauveau</surname><given-names>V</given-names></name><name><surname>Mamdani</surname><given-names>M</given-names></name><name><surname>Steinglass</surname><given-names>R</given-names></name><name><surname>Koblinsky</surname><given-names>M</given-names></name></person-group><article-title>Maternal tetanus: magnitude, epidemiology and potential control measures</article-title><source>International Journal of Gynecology and Obstetrics</source><year>1993</year><volume>40</volume><fpage>3</fpage><lpage>12</lpage><pub-id pub-id-type="pmid">8094347</pub-id></element-citation></ref><ref id="b61"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Feldmeier</surname><given-names>H</given-names></name><name><surname>Poggensee</surname><given-names>G</given-names></name><name><surname>Krantz</surname><given-names>I</given-names></name><name><surname>Helling-Giese</surname><given-names>G</given-names></name></person-group><article-title>Female genital schistosomiasis. New challenges from a gender perspective</article-title><source>Tropical and Geographical Medicine</source><year>1995</year><volume>47</volume><fpage>1</fpage><lpage>15</lpage></element-citation></ref><ref id="b62"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ferris</surname><given-names>ITJ</given-names></name><name><surname>Ortega Garcia</surname><given-names>JA</given-names></name><name><surname>Garcia</surname><given-names>ICJ</given-names></name><etal></etal></person-group><article-title>Risks factors for pediatric malignant liver tumors</article-title><source>Anales de Pediatria</source><year>2008</year><volume>68</volume><fpage>377</fpage><lpage>384</lpage><pub-id pub-id-type="pmid">18394385</pub-id></element-citation></ref><ref id="b63"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fewtrell</surname><given-names>L</given-names></name><name><surname>Fuge</surname><given-names>R</given-names></name><name><surname>Kay</surname><given-names>D</given-names></name></person-group><article-title>An estimation of the global burden of disease due to skin lesions caused by arsenic in drinking water</article-title><source>Journal of Water and Health</source><year>2005</year><volume>3</volume><fpage>101</fpage><lpage>107</lpage><pub-id pub-id-type="pmid">16075937</pub-id></element-citation></ref><ref id="b64"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Figà-Talamanca</surname><given-names>I</given-names></name></person-group><article-title>Occupational risk factors and reproductive health of women</article-title><source>Occupational Medicine</source><year>2006</year><volume>56</volume><fpage>521</fpage><lpage>531</lpage><pub-id pub-id-type="pmid">17151388</pub-id></element-citation></ref><ref id="b65"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fincham</surname><given-names>J</given-names></name><name><surname>Markus</surname><given-names>M</given-names></name><name><surname>Adams</surname><given-names>V</given-names></name></person-group><article-title>Could control of soil-transmitted helminthic infection influence the HIV/AIDS pandemic</article-title><source>Acta Tropica</source><year>2003</year><volume>86</volume><fpage>315</fpage><lpage>333</lpage><pub-id pub-id-type="pmid">12745148</pub-id></element-citation></ref><ref id="b66"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fischer Walker</surname><given-names>C</given-names></name><name><surname>Perin</surname><given-names>J</given-names></name><name><surname>Aryee</surname><given-names>M</given-names></name><name><surname>Boschi-Pinto</surname><given-names>C</given-names></name><name><surname>Black</surname><given-names>R</given-names></name></person-group><article-title>Diarrhea incidence in low- and middle-income countries in 1990 and 2010: a systematic review</article-title><source>BMC Public Health</source><year>2012</year><volume>12</volume><fpage>220</fpage><comment>doi: <ext-link ext-link-type="doi" xlink:href="10.1186/1471-2458-12-220">10.1186/1471-2458-12-220</ext-link></comment><pub-id pub-id-type="pmid">22436130</pub-id></element-citation></ref><ref id="b67"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Florack</surname><given-names>E</given-names></name><name><surname>Zielhuis</surname><given-names>G</given-names></name><name><surname>Pellegrino</surname><given-names>J</given-names></name><name><surname>Rolland</surname><given-names>R</given-names></name></person-group><article-title>Occupational physical activity and the occurrence of spontaneous abortion</article-title><source>International Journal of Epidemiology</source><year>1993</year><volume>22</volume><fpage>878</fpage><lpage>884</lpage><pub-id pub-id-type="pmid">8282467</pub-id></element-citation></ref><ref id="b68"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Fowler</surname><given-names>P</given-names></name><name><surname>Bellingham</surname><given-names>M</given-names></name><name><surname>Sinclair</surname><given-names>K</given-names></name><etal></etal></person-group><article-title>Impact of endocrine-disrupting compounds (EDCs) on female reproductive health</article-title><source>Molecular and Cellular Endocrinology</source><year>2012</year><volume>355</volume><fpage>231</fpage><lpage>239</lpage><pub-id pub-id-type="pmid">22061620</pub-id></element-citation></ref><ref id="b69"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Gadgil</surname><given-names>A</given-names></name></person-group><article-title>Drinking water in developing countries</article-title><source>Annual Review of Energy and the Environment</source><year>1998</year><volume>23</volume><fpage>253</fpage><lpage>286</lpage></element-citation></ref><ref id="b70"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Gil</surname><given-names>A</given-names></name><name><surname>Lanata</surname><given-names>C</given-names></name><name><surname>Kleinau</surname><given-names>E</given-names></name><name><surname>Penny</surname><given-names>M</given-names></name></person-group><source>Strategic Report 11: Children's Feces Disposal Practices in Developing Countries and Interventions to Prevent Diarrheal Diseases: A Literature Review</source><year>2004</year><publisher-loc>Peru</publisher-loc><publisher-name>Instituto de Investigacion Nutricional</publisher-name></element-citation></ref><ref id="b71"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Goldenberg</surname><given-names>RL</given-names></name><name><surname>Thompson</surname><given-names>C</given-names></name></person-group><article-title>The infectious origins of stillbirth</article-title><source>American Journal of Obstetrics & Gynecology</source><year>2003</year><volume>189</volume><fpage>861</fpage><lpage>873</lpage><pub-id pub-id-type="pmid">14526331</pub-id></element-citation></ref><ref id="b72"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Gon</surname><given-names>G</given-names></name><name><surname>Monzon-Llamas</surname><given-names>L</given-names></name><name><surname>Benova</surname><given-names>L</given-names></name><name><surname>Willey</surname><given-names>B</given-names></name><name><surname>Campbell</surname><given-names>O</given-names></name></person-group><article-title>The contribution of unimproved water and toilet facilities to pregnancy-related mortality in Afghanistan: analysis of the Afghan Mortality Survey</article-title><source>Tropical Medicine & International Health</source><year>2014</year><volume>19</volume><fpage>1488</fpage><lpage>1499</lpage><pub-id pub-id-type="pmid">25330354</pub-id></element-citation></ref><ref id="b73"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Gordon</surname><given-names>A</given-names></name></person-group><source>A Treatise on the Epidemic of Puerperal Fever of Aberdeen</source><year>1795</year><publisher-loc>London</publisher-loc><publisher-name>GG and J Robinson</publisher-name></element-citation></ref><ref id="b74"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Grellier</surname><given-names>J</given-names></name><name><surname>Bennett</surname><given-names>J</given-names></name><name><surname>Patelarou</surname><given-names>E</given-names></name><etal></etal></person-group><article-title>Exposure to disinfection by-products, fetal growth, and prematurity: a systematic review and meta-analysis</article-title><source>Epidemiology</source><year>2010</year><volume>21</volume><fpage>300</fpage><lpage>313</lpage><pub-id pub-id-type="pmid">20375841</pub-id></element-citation></ref><ref id="b75"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Guerrant</surname><given-names>R</given-names></name><name><surname>Kosek</surname><given-names>M</given-names></name><name><surname>Moore</surname><given-names>S</given-names></name><etal></etal></person-group><article-title>Magnitude and impact of diarrheal diseases</article-title><source>Archives of Medical Research</source><year>2002</year><volume>33</volume><fpage>351</fpage><lpage>355</lpage><pub-id pub-id-type="pmid">12234524</pub-id></element-citation></ref><ref id="b76"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Guerrant</surname><given-names>R</given-names></name><name><surname>Deboer</surname><given-names>M</given-names></name><name><surname>Moore</surname><given-names>S</given-names></name><name><surname>Scharf</surname><given-names>R</given-names></name><name><surname>Lima</surname><given-names>A</given-names></name></person-group><article-title>The impoverished gut-a triple burden of diarrhoea, stunting and chronic disease</article-title><source>Nature Reviews Gastroenterology and Hepatology</source><year>2012</year><volume>10</volume><fpage>220</fpage><lpage>229</lpage><comment>(epub) doi: <ext-link ext-link-type="doi" xlink:href="10.1038/nrgastro.2012.1239">10.1038/nrgastro.2012.1239</ext-link></comment></element-citation></ref><ref id="b77"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Gyapong</surname><given-names>J</given-names></name><name><surname>Chinbuah</surname><given-names>M</given-names></name><name><surname>Gyapong</surname><given-names>M</given-names></name></person-group><article-title>Inadvertent exposure of pregnant women to ivermectin and albendazole during mass drug administration for lymphatic filariasis</article-title><source>Tropical Medicine & International Health</source><year>2003</year><volume>8</volume><fpage>1093</fpage><lpage>1101</lpage><pub-id pub-id-type="pmid">14641844</pub-id></element-citation></ref><ref id="b78"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Hannan</surname><given-names>C</given-names></name><name><surname>Andersson</surname><given-names>I</given-names></name></person-group><source>Gender Perspectives on Ecological Sanitation</source><year>2002</year><comment><ext-link ext-link-type="uri" xlink:href="http://www2.gtz.de/dokumente/oe44/ecosan/en-gender-perspectives-ecological-sanitation-2002.pdf">http://www2.gtz.de/dokumente/oe44/ecosan/en-gender-perspectives-ecological-sanitation-2002.pdf</ext-link> Accessed on December 28, 2012</comment></element-citation></ref><ref id="b79"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Henderson</surname><given-names>L</given-names></name><name><surname>Tulloch</surname><given-names>J</given-names></name></person-group><article-title>Incentives for retaining and motivating health workers in Pacific and Asian countries</article-title><source>Human Resources for Health</source><year>2008</year><volume>6</volume><fpage>18</fpage><comment>doi: <ext-link ext-link-type="doi" xlink:href="10.1186/1478-4491-6-18">10.1186/1478-4491-6-18</ext-link></comment><pub-id pub-id-type="pmid">18793436</pub-id></element-citation></ref><ref id="b80"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Heymann</surname><given-names>DL</given-names></name></person-group><source>Control of Communicable Diseases Manual</source><year>2008</year><publisher-loc>Washington DC</publisher-loc><publisher-name>American Public Health Association</publisher-name></element-citation></ref><ref id="b81"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Horton</surname><given-names>R</given-names></name></person-group><article-title>Offline: what kind of world do you want post-2015?</article-title><source>The Lancet</source><year>2012</year><volume>380</volume><fpage>1214</fpage></element-citation></ref><ref id="b82"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ilahi</surname><given-names>N</given-names></name><name><surname>Grimard</surname><given-names>F</given-names></name></person-group><article-title>Public infrastructure and private costs: water supply and time allocation of women in rural Pakistan</article-title><source>Economic Development and Cultural Change</source><year>2000</year><volume>49</volume><fpage>45</fpage><lpage>75</lpage></element-citation></ref><ref id="b83"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ishaque</surname><given-names>S</given-names></name><name><surname>Yakoob</surname><given-names>MY</given-names></name><name><surname>Imdad</surname><given-names>A</given-names></name><etal></etal></person-group><article-title>Effectiveness of interventions to screen and manage infections during pregnancy on reducing stillbirths: a review</article-title><source>BMC Public Health</source><year>2011</year><volume>11</volume><issue>Suppl 3</issue><fpage>S3</fpage><pub-id pub-id-type="pmid">21501448</pub-id></element-citation></ref><ref id="b84"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Jamieson</surname><given-names>D</given-names></name><name><surname>Theiler</surname><given-names>R</given-names></name><name><surname>Rasmussen</surname><given-names>S</given-names></name></person-group><article-title>Emerging infections and pregnancy</article-title><source>Emerging Infectious Diseases</source><year>2006</year><volume>12</volume><fpage>1638</fpage><lpage>1643</lpage><pub-id pub-id-type="pmid">17283611</pub-id></element-citation></ref><ref id="b85"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Janakiraman</surname><given-names>V</given-names></name></person-group><article-title>Listeriosis in pregnancy: diagnosis, treatment, and prevention</article-title><source>Reviews in Obstetrics & Gynecology</source><year>2008</year><volume>1</volume><fpage>179</fpage><lpage>185</lpage><pub-id pub-id-type="pmid">19173022</pub-id></element-citation></ref><ref id="b86"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Jones</surname><given-names>R</given-names></name><name><surname>Finlay</surname><given-names>F</given-names></name></person-group><article-title>Sanitary towel provision and disposal in primary schools</article-title><source>Child: Care, Health and Development</source><year>2001</year><volume>27</volume><fpage>85</fpage><lpage>92</lpage></element-citation></ref><ref id="b87"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Jorgensen</surname><given-names>S</given-names></name><name><surname>Hein</surname><given-names>H</given-names></name><name><surname>Gyntelberg</surname><given-names>F</given-names></name></person-group><article-title>Heavy lifting at work and risk of genital prolapse and herniated lumber disc in assistant nurses</article-title><source>Occupational Medicine</source><year>1994</year><volume>44</volume><fpage>47</fpage><lpage>49</lpage><pub-id pub-id-type="pmid">8167320</pub-id></element-citation></ref><ref id="b88"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Khan</surname><given-names>A</given-names></name><name><surname>Ireson</surname><given-names>A</given-names></name><name><surname>Kovats</surname><given-names>S</given-names></name><etal></etal></person-group><article-title>Drinking water salinity and maternal health in coastal Bangladesh: implications of climate change</article-title><source>Environmental Health Perspectives</source><year>2011</year><volume>119</volume><fpage>1328</fpage><lpage>1332</lpage></element-citation></ref><ref id="b89"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>King</surname><given-names>W</given-names></name><name><surname>Dodds</surname><given-names>L</given-names></name><name><surname>Allen</surname><given-names>A</given-names></name></person-group><article-title>Relation between stillbirth and specific chlorination by-products in public water supplies</article-title><source>Environmental Health Perspectives</source><year>2000</year><volume>108</volume><fpage>883</fpage><lpage>886</lpage><pub-id pub-id-type="pmid">11017894</pub-id></element-citation></ref><ref id="b90"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>King</surname><given-names>C</given-names></name><name><surname>Dickman</surname><given-names>K</given-names></name><name><surname>Tisch</surname><given-names>D</given-names></name></person-group><article-title>Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability related outcomes in endemic schistosomiasis</article-title><source>Lancet</source><year>2005</year><volume>365</volume><fpage>1561</fpage><lpage>1569</lpage><pub-id pub-id-type="pmid">15866310</pub-id></element-citation></ref><ref id="b91"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kirschstein</surname><given-names>R</given-names></name></person-group><article-title>Research on women's health</article-title><source>American Journal of Public Health</source><year>1991</year><volume>81</volume><fpage>291</fpage><lpage>293</lpage><pub-id pub-id-type="pmid">1994737</pub-id></element-citation></ref><ref id="b92"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kistemann</surname><given-names>T</given-names></name></person-group><article-title>Waterborne hazards in children</article-title><source>Annales Nestlè</source><year>2004</year><volume>62</volume><fpage>55</fpage><lpage>65</lpage></element-citation></ref><ref id="b93"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Koolwal</surname><given-names>G</given-names></name><name><surname>van de Walle</surname><given-names>D</given-names></name></person-group><source>Access to Water, Women's Work and Child Outcomes</source><year>2010</year><publisher-loc>Washington DC</publisher-loc><publisher-name>Word Bank</publisher-name></element-citation></ref><ref id="b94"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kourtis</surname><given-names>AP</given-names></name><name><surname>Read</surname><given-names>JS</given-names></name><name><surname>Jamieson</surname><given-names>DJ</given-names></name></person-group><article-title>Pregnancy and infection</article-title><source>New England Journal of Medicine</source><year>2014</year><volume>370</volume><fpage>2211</fpage><lpage>2218</lpage><pub-id pub-id-type="pmid">24897084</pub-id></element-citation></ref><ref id="b95"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Krieger</surname><given-names>N</given-names></name><name><surname>Zierler</surname><given-names>S</given-names></name></person-group><article-title>What explains the public's health? A call for epidemiologic theory</article-title><source>Epidemiology</source><year>1996</year><volume>7</volume><fpage>107</fpage><lpage>109</lpage><pub-id pub-id-type="pmid">8664390</pub-id></element-citation></ref><ref id="b96"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kuh</surname><given-names>D</given-names></name><name><surname>Ben-Shlomo</surname><given-names>Y</given-names></name><name><surname>Lynch</surname><given-names>J</given-names></name><name><surname>Hallqvist</surname><given-names>J</given-names></name><name><surname>Power</surname><given-names>C</given-names></name></person-group><article-title>Life course epidemiology</article-title><source>Journal of Epidemiology and Community Health</source><year>2003</year><volume>57</volume><fpage>778</fpage><lpage>783</lpage><pub-id pub-id-type="pmid">14573579</pub-id></element-citation></ref><ref id="b97"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Kurtis</surname><given-names>J</given-names></name><name><surname>Higashi</surname><given-names>A</given-names></name><name><surname>Wu</surname><given-names>H</given-names></name><etal></etal></person-group><article-title>Maternal <italic>Schistosomiasis japonica</italic> is associated with maternal, placental, and fetal inflammation</article-title><source>Infection and Immunity</source><year>2011</year><volume>79</volume><fpage>1254</fpage><lpage>1261</lpage><pub-id pub-id-type="pmid">21149589</pub-id></element-citation></ref><ref id="b98"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lamont</surname><given-names>RF</given-names></name><name><surname>Sobel</surname><given-names>J</given-names></name><name><surname>Mazaki-Tovi</surname><given-names>S</given-names></name><etal></etal></person-group><article-title>Listeriosis in human pregnancy: a systematic review</article-title><source>Journal of Perinatal Medicine</source><year>2011</year><volume>39</volume><fpage>227</fpage><lpage>236</lpage><pub-id pub-id-type="pmid">21517700</pub-id></element-citation></ref><ref id="b99"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Lawson</surname><given-names>D</given-names></name></person-group><source>A Gendered Analysis of ‘Time Poverty’ and the Importance of Infrastructure</source><year>2007</year><publisher-loc>Manchester</publisher-loc><publisher-name>Global Poverty Research Group</publisher-name></element-citation></ref><ref id="b100"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Le Hesran</surname><given-names>J</given-names></name><name><surname>Akiana</surname><given-names>J</given-names></name><name><surname>Ndiaye</surname><given-names>E</given-names></name><etal></etal></person-group><article-title>Severe malaria attack is associated with high prevalence of Ascaris lumbricoides infection among children in rural Senegal</article-title><source>Transactions of the Royal Society of Tropical Medicine and Hygiene</source><year>2004</year><volume>98</volume><fpage>397</fpage><lpage>399</lpage><pub-id pub-id-type="pmid">15138075</pub-id></element-citation></ref><ref id="b101"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Lennon</surname><given-names>S</given-names></name></person-group><source>Fear and Anger: Perceptions of Risks Related to Sexual Violence Against Women Linked to Water and Sanitation in Delhi, India</source><year>2011</year><publisher-loc>London, UK</publisher-loc><publisher-name>WaterAid</publisher-name></element-citation></ref><ref id="b102"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lettieri</surname><given-names>L</given-names></name><name><surname>Vintzileos</surname><given-names>AM</given-names></name><name><surname>Rodis</surname><given-names>JF</given-names></name><name><surname>Albini</surname><given-names>SM</given-names></name><name><surname>Salafia</surname><given-names>CM</given-names></name></person-group><article-title>Does “idiopathic” preterm labor resulting in preterm birth exist?</article-title><source>American Journal of Obstetrics and Gynecology</source><year>1993</year><volume>168</volume><fpage>1480</fpage><lpage>1485</lpage><pub-id pub-id-type="pmid">8498431</pub-id></element-citation></ref><ref id="b103"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Levac</surname><given-names>D</given-names></name><name><surname>Colquhoun</surname><given-names>H</given-names></name><name><surname>O'Brien</surname><given-names>KK</given-names></name></person-group><article-title>Scoping studies: advancing the methodology</article-title><source>Implementation Science</source><year>2010</year><volume>5</volume><fpage>69</fpage><pub-id pub-id-type="pmid">20854677</pub-id></element-citation></ref><ref id="b104"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lima</surname><given-names>A</given-names></name><name><surname>Moore</surname><given-names>S</given-names></name><name><surname>Barboza</surname><given-names>MJ</given-names></name><etal></etal></person-group><article-title>Persistent diarrhea signals a critical period of increased diarrhea burdens and nutritional shortfalls: a prospective cohort study among children in northeastern Brazil</article-title><source>Journal of Infectious Diseases</source><year>2000</year><volume>181</volume><fpage>1643</fpage><lpage>1651</lpage><pub-id pub-id-type="pmid">10823764</pub-id></element-citation></ref><ref id="b105"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lindner</surname><given-names>AK</given-names></name><name><surname>Priotto</surname><given-names>G</given-names></name></person-group><article-title>The unknown risk of vertical transmission in sleeping sickness–a literature review</article-title><source>PLoS Neglected Tropical Diseases</source><year>2010</year><volume>4</volume><fpage>e783</fpage><pub-id pub-id-type="pmid">21200416</pub-id></element-citation></ref><ref id="b106"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Liu</surname><given-names>L</given-names></name><name><surname>Johnson</surname><given-names>H</given-names></name><name><surname>Cousens</surname><given-names>S</given-names></name><etal></etal></person-group><article-title>Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000</article-title><source>The Lancet</source><year>2012</year><volume>379</volume><fpage>2151</fpage><lpage>2161</lpage></element-citation></ref><ref id="b107"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Lopez Duenas</surname><given-names>A</given-names></name><name><surname>Aldea Romero</surname><given-names>AE</given-names></name><name><surname>Sanz Anquela</surname><given-names>JM</given-names></name><name><surname>Jimenez Bustos</surname><given-names>JM</given-names></name></person-group><article-title>Childhood cancer of occupations origin: leukemia and lymphomas</article-title><source>Revista Espanola de Pediatria</source><year>2012</year><volume>68</volume><fpage>59</fpage><lpage>64</lpage></element-citation></ref><ref id="b108"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Maduka</surname><given-names>C</given-names></name><name><surname>Nweke</surname><given-names>L</given-names></name><name><surname>Miri</surname><given-names>E</given-names></name><etal></etal></person-group><article-title>Missed treatment opportunities, for pregnant and breast-feeding women, in onchocerciasis mass-treatment programmes in south-eastern Nigeria</article-title><source>Annals of Tropical Medicine and Parasitology</source><year>2004</year><volume>98</volume><fpage>697</fpage><lpage>702</lpage><pub-id pub-id-type="pmid">15509423</pub-id></element-citation></ref><ref id="b109"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Main</surname><given-names>E</given-names></name><name><surname>Morton</surname><given-names>CH</given-names></name><name><surname>Melsop</surname><given-names>KM</given-names></name><etal></etal></person-group><article-title>Creating a public agenda for maternity safety and quality in cesarean delivery</article-title><source>Obstetrics & Gynecology</source><year>2012</year><volume>120</volume><fpage>1194</fpage><lpage>1198</lpage><pub-id pub-id-type="pmid">23090538</pub-id></element-citation></ref><ref id="b110"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mamman</surname><given-names>L</given-names></name><name><surname>Brieger</surname><given-names>W</given-names></name><name><surname>Oshiname</surname><given-names>F</given-names></name></person-group><article-title>Alcohol consumption pattern among women in a rural Yoruba community in Nigeria</article-title><source>Substance Use & Misuse</source><year>2002</year><volume>37</volume><fpage>579</fpage><lpage>597</lpage><pub-id pub-id-type="pmid">12117061</pub-id></element-citation></ref><ref id="b111"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Manassaram</surname><given-names>D</given-names></name><name><surname>Backer</surname><given-names>L</given-names></name><name><surname>Moll</surname><given-names>D</given-names></name></person-group><article-title>A review of nitrates in drinking water: maternal exposure and adverse reproductive and developmental outcomes</article-title><source>Environmental Health Perspectives</source><year>2006</year><volume>114</volume><fpage>320</fpage><lpage>327</lpage><pub-id pub-id-type="pmid">16507452</pub-id></element-citation></ref><ref id="b112"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Massey</surname><given-names>K</given-names></name></person-group><source>Insecurity and Shame: Exploration of the Impact of the Lack of Sanitation on Women in the Slums of Kampala, Uganda</source><year>2011</year><publisher-loc>London, UK</publisher-loc><publisher-name>WaterAid</publisher-name></element-citation></ref><ref id="b113"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mazor-Dray</surname><given-names>E</given-names></name><name><surname>Levy</surname><given-names>A</given-names></name><name><surname>Schlaeffer</surname><given-names>F</given-names></name><name><surname>Sheiner</surname><given-names>E</given-names></name></person-group><article-title>Maternal urinary tract infection: is it independently associated with adverse pregnancy outcome?</article-title><source>The Journal of Maternal-Fetal & Neonatal Medicine</source><year>2009</year><volume>22</volume><fpage>124</fpage><lpage>128</lpage><pub-id pub-id-type="pmid">19085630</pub-id></element-citation></ref><ref id="b114"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>McGready</surname><given-names>R</given-names></name><name><surname>Lee</surname><given-names>S</given-names></name><name><surname>Wiladphaingern</surname><given-names>J</given-names></name><etal></etal></person-group><article-title>Adverse effects of falciparum and vivax malaria and the safety of antimalarial treatment in early pregnancy: a population-based study</article-title><source>The Lancet. Infectious Diseases</source><year>2012</year><volume>12</volume><fpage>388</fpage><lpage>396</lpage><pub-id pub-id-type="pmid">22169409</pub-id></element-citation></ref><ref id="b115"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Menezes</surname><given-names>EV</given-names></name><name><surname>Yakoob</surname><given-names>MY</given-names></name><name><surname>Soomro</surname><given-names>T</given-names></name><etal></etal></person-group><article-title>Reducing stillbirths: prevention and management of medical disorders and infections during pregnancy</article-title><source>BMC Pregnancy and Childbirth</source><year>2009</year><volume>9</volume><issue>Suppl 1</issue><fpage>S4</fpage><pub-id pub-id-type="pmid">19426467</pub-id></element-citation></ref><ref id="b116"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Miles</surname><given-names>MB</given-names></name><name><surname>Huberman</surname><given-names>AM</given-names></name></person-group><source>Qualitative Data Analysis: An Expanded Source Book</source><year>1994</year><publisher-loc>Newbury Park, CA</publisher-loc><publisher-name>Sage</publisher-name><comment>Cited in Jabareen Y (2009) Building a conceptual framework: philosophy, definitions and procedures. <italic>International Journal for Qualitative Methods</italic><bold>2008</bold></comment></element-citation></ref><ref id="b117"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Milton</surname><given-names>AH</given-names></name><name><surname>Smith</surname><given-names>W</given-names></name><name><surname>Rahman</surname><given-names>B</given-names></name><etal></etal></person-group><article-title>Chronic arsenic exposure and adverse pregnancy outcomes in Bangladesh</article-title><source>Epidemiology</source><year>2005</year><volume>16</volume><fpage>82</fpage><lpage>86</lpage><pub-id pub-id-type="pmid">15613949</pub-id></element-citation></ref><ref id="b118"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Minassian</surname><given-names>C</given-names></name><name><surname>Thomas</surname><given-names>SL</given-names></name><name><surname>Williams</surname><given-names>DJ</given-names></name><name><surname>Campbell</surname><given-names>O</given-names></name><name><surname>Smeeth</surname><given-names>L</given-names></name></person-group><article-title>Acute maternal infection and risk of pre-eclampsia: a population-based case-control study</article-title><source>PLoS One</source><year>2013</year><volume>8</volume><fpage>e73047</fpage><pub-id pub-id-type="pmid">24019891</pub-id></element-citation></ref><ref id="b119"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mishra</surname><given-names>G</given-names></name><name><surname>Cooper</surname><given-names>R</given-names></name><name><surname>Kuh</surname><given-names>D</given-names></name></person-group><article-title>A life course approach to reproductive health: theory and methods</article-title><source>Maturitas</source><year>2010</year><volume>65</volume><fpage>92</fpage><lpage>97</lpage><pub-id pub-id-type="pmid">20079587</pub-id></element-citation></ref><ref id="b120"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Moist</surname><given-names>L</given-names></name><name><surname>Sontrop</surname><given-names>J</given-names></name><name><surname>Garg</surname><given-names>A</given-names></name><etal></etal></person-group><article-title>Risk of pregnancy-related hypertension within five years of exposure to bacteria-contaminated drinking water</article-title><source>Kidney International. Supplement</source><year>2009</year><volume>112</volume><fpage>S47</fpage><lpage>S49</lpage><pub-id pub-id-type="pmid">19180135</pub-id></element-citation></ref><ref id="b121"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mosby</surname><given-names>LG</given-names></name><name><surname>Rasmussen</surname><given-names>SA</given-names></name><name><surname>Jamieson</surname><given-names>DJ</given-names></name></person-group><article-title>2009 pandemic influenza A (H1N1) in pregnancy: a systematic review of the literature</article-title><source>American Journal of Obstetrics and Gynecology</source><year>2011</year><volume>205</volume><fpage>10</fpage><lpage>18</lpage><pub-id pub-id-type="pmid">21345415</pub-id></element-citation></ref><ref id="b122"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mota</surname><given-names>A</given-names></name><name><surname>Miranda Filho</surname><given-names>A</given-names></name><name><surname>Saraceni</surname><given-names>V</given-names></name><name><surname>Koifman</surname><given-names>S</given-names></name></person-group><article-title>Maternal mortality and impact of dengue in Southeast Brazil: an ecological study, 2001–2005</article-title><source>Cadernos de Saúde Pública</source><year>2012</year><volume>28</volume><fpage>1057</fpage><lpage>1066</lpage><pub-id pub-id-type="pmid">22666810</pub-id></element-citation></ref><ref id="b123"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Moubayed</surname><given-names>P</given-names></name><name><surname>Ziehe</surname><given-names>A</given-names></name><name><surname>Peters</surname><given-names>J</given-names></name><name><surname>Mwakyoma</surname><given-names>H</given-names></name><name><surname>Schmidt</surname><given-names>D</given-names></name></person-group><article-title>Carcinoma of the uterine cervix associated with schistosomiasis and induced by human papillomaviruses</article-title><source>International Journal of Gynecology & Obstetrics</source><year>1995</year><volume>49</volume><fpage>175</fpage><lpage>179</lpage><pub-id pub-id-type="pmid">7649324</pub-id></element-citation></ref><ref id="b124"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Mukhtar</surname><given-names>M</given-names></name><name><surname>Ensink</surname><given-names>J</given-names></name><name><surname>van der Hoek</surname><given-names>W</given-names></name><name><surname>Amerasinghe</surname><given-names>F</given-names></name><name><surname>Konradsen</surname><given-names>F</given-names></name></person-group><article-title>Importance of waste stabilization ponds and wastewater irrigation in the generation of vector mosquitoes in Pakistan</article-title><source>Journal of Medical Entomology</source><year>2006</year><volume>43</volume><fpage>996</fpage><lpage>1003</lpage><pub-id pub-id-type="pmid">17017239</pub-id></element-citation></ref><ref id="b125"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Murray</surname><given-names>C</given-names></name><name><surname>Vos</surname><given-names>T</given-names></name><name><surname>Lozano</surname><given-names>R</given-names></name><etal></etal></person-group><article-title>Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010</article-title><source>The Lancet</source><year>2012</year><volume>380</volume><fpage>2197</fpage><lpage>2223</lpage></element-citation></ref><ref id="b126"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Nauges</surname><given-names>C</given-names></name><name><surname>Strand</surname><given-names>J</given-names></name></person-group><source>Water Hauling and Girls’ School Attendance: Some New Evidence From Ghana</source><year>2011</year><comment><ext-link ext-link-type="uri" xlink:href="http://water.worldbank.org/sites/water.worldbank.org/files/Water%20hauling%20and%20Girls%20school%20attendabce_Ghana_Strand%20&%20Nauges%2026%20May%202011_0.pdf">http://water.worldbank.org/sites/water.worldbank.org/files/Water%20hauling%20and%20Girls%20school%20attendabce_Ghana_Strand%20&%20Nauges%2026%20May%202011_0.pdf</ext-link> Accessed: December 7, 2014</comment></element-citation></ref><ref id="b127"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Nicolle-Mir</surname><given-names>L</given-names></name></person-group><article-title>Pesticide exposure and cancers in children: meta-analysis of recent studies</article-title><source>Environnement, Risques, et Sante</source><year>2012</year><volume>11</volume><fpage>191</fpage><lpage>192</lpage></element-citation></ref><ref id="b128"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Nolan</surname><given-names>C</given-names></name><name><surname>Shaikh</surname><given-names>Z</given-names></name></person-group><article-title>Lead nephrotoxicity and associated disorders: biochemical mechanisms</article-title><source>Toxicology</source><year>1992</year><volume>73</volume><fpage>127</fpage><lpage>146</lpage><pub-id pub-id-type="pmid">1319092</pub-id></element-citation></ref><ref id="b129"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Noronha</surname><given-names>JA</given-names></name><name><surname>Al Khasawneh</surname><given-names>E</given-names></name><name><surname>Seshan</surname><given-names>V</given-names></name><name><surname>Ramasubramaniam</surname><given-names>S</given-names></name><name><surname>Raman</surname><given-names>S</given-names></name></person-group><article-title>Anemia in pregnancy-consequences and challenges: a review of literature</article-title><source>Journal of South Asian Federation of Obstetrics and Gynecology</source><year>2012</year><volume>1</volume><fpage>64</fpage><lpage>70</lpage></element-citation></ref><ref id="b130"><element-citation publication-type="other"><person-group person-group-type="author"><name><surname>Novak</surname><given-names>J</given-names></name><name><surname>Canas</surname><given-names>A</given-names></name></person-group><year>2008</year><comment>The Theory Underlying Concept Maps and How to Construct and Use Them. Florida Institute for Human and Machine Cognition. Available at <ext-link ext-link-type="uri" xlink:href="http://cmap.ihmc.us/Publications/ResearchPapers/TheoryUnderlyingConceptMaps.pdf">http://cmap.ihmc.us/Publications/ResearchPapers/TheoryUnderlyingConceptMaps.pdf</ext-link></comment></element-citation></ref><ref id="b131"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Nygaard</surname><given-names>I</given-names></name><name><surname>Linder</surname><given-names>M</given-names></name></person-group><article-title>Thirst at work-an occupational hazard?</article-title><source>International Urogynecology Journal and Pelvic Floor Dysfunction</source><year>1997</year><volume>8</volume><fpage>340</fpage><lpage>343</lpage><pub-id pub-id-type="pmid">9609332</pub-id></element-citation></ref><ref id="b132"><element-citation publication-type="book"><collab>Partnership for Maternal Newborn and Child Health</collab><source>PMNCH Fact Sheet: RMNCH Continuum of Care: Reproductive, Maternal, Newborn and Child Health</source><year>2011</year><publisher-loc>Geneva</publisher-loc><publisher-name>World Health Organization</publisher-name></element-citation></ref><ref id="b133"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Peters</surname><given-names>C</given-names></name><name><surname>Harling</surname><given-names>M</given-names></name><name><surname>Dulon</surname><given-names>M</given-names></name><etal></etal></person-group><article-title>Fertility disorders and pregnancy complications in hairdressers – a systematic review</article-title><source>Journal of Occupational Medicine and Toxicology</source><year>2010</year><volume>5</volume><fpage>24</fpage><comment>doi: <ext-link ext-link-type="doi" xlink:href="10.1186/1745-6673-5-24">10.1186/1745-6673-5-24</ext-link></comment><pub-id pub-id-type="pmid">20723211</pub-id></element-citation></ref><ref id="b134"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pocock</surname><given-names>S</given-names></name><name><surname>Smith</surname><given-names>M</given-names></name><name><surname>Baghurst</surname><given-names>P</given-names></name></person-group><article-title>Environmental lead and children's intelligence: a systematic review of the epidemiological evidence</article-title><source>BMJ</source><year>1994</year><volume>309</volume><fpage>1189</fpage><lpage>1197</lpage><pub-id pub-id-type="pmid">7987149</pub-id></element-citation></ref><ref id="b135"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Potukuchi</surname><given-names>P</given-names></name><name><surname>Rao</surname><given-names>P</given-names></name></person-group><article-title>Problem alcohol drinking in rural women of Telangana region, Andhra Pradesh</article-title><source>Indian Journal of Psychiatry</source><year>2010</year><volume>52</volume><fpage>339</fpage><lpage>343</lpage><pub-id pub-id-type="pmid">21267368</pub-id></element-citation></ref><ref id="b136"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Pouliot</surname><given-names>S</given-names></name><name><surname>Xiong</surname><given-names>X</given-names></name><name><surname>Harville</surname><given-names>E</given-names></name><etal></etal></person-group><article-title>Maternal dengue and pregnancy outcomes: a systematic review</article-title><source>Obstetrical & Gynecological Survey</source><year>2010</year><volume>35</volume><fpage>107</fpage><lpage>118</lpage><pub-id pub-id-type="pmid">20100360</pub-id></element-citation></ref><ref id="b137"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Prüss-Üstün</surname><given-names>A</given-names></name><name><surname>Bos</surname><given-names>R</given-names></name><name><surname>Gore</surname><given-names>F</given-names></name><name><surname>Bartram</surname><given-names>J</given-names></name></person-group><source>Safer Water, Better Health: Costs, Benefits and Sustainability of Interventions to Protect and Promote Health</source><year>2008</year><publisher-loc>Geneva</publisher-loc><publisher-name>World Health Organization</publisher-name></element-citation></ref><ref id="b138"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Qunhua</surname><given-names>L</given-names></name><name><surname>Jiawen</surname><given-names>Z</given-names></name><name><surname>Bozhao</surname><given-names>L</given-names></name><etal></etal></person-group><article-title>Investigation of association between female genital tract diseases and <italic>Schistosomiasis japonica</italic> infection</article-title><source>Acta Tropica</source><year>2000</year><volume>77</volume><fpage>179</fpage><lpage>183</lpage><pub-id pub-id-type="pmid">11080508</pub-id></element-citation></ref><ref id="b139"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rabie</surname><given-names>T</given-names></name><name><surname>Curtis</surname><given-names>V</given-names></name></person-group><article-title>Handwashing and risk of respiratory infections: a quantitative systematic review</article-title><source>Tropical Medicine & International Health</source><year>2006</year><volume>11</volume><fpage>258</fpage><lpage>267</lpage><pub-id pub-id-type="pmid">16553905</pub-id></element-citation></ref><ref id="b140"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rahman</surname><given-names>A</given-names></name><name><surname>Vahter</surname><given-names>M</given-names></name><name><surname>Ekstrom</surname><given-names>EC</given-names></name><name><surname>Rahman</surname><given-names>M</given-names></name><name><surname>Haider</surname><given-names>A</given-names></name></person-group><article-title>Association of arsenic exposure during pregnancy with fetal loss and infant death: a cohort study in Bangladesh</article-title><source>American Journal of Epidemiology</source><year>2007</year><volume>165</volume><fpage>1389</fpage><lpage>1396</lpage><pub-id pub-id-type="pmid">17351293</pub-id></element-citation></ref><ref id="b141"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rahman</surname><given-names>A</given-names></name><name><surname>Persson</surname><given-names>LA</given-names></name><name><surname>Nermell</surname><given-names>B</given-names></name><etal></etal></person-group><article-title>Arsenic exposure and risk of spontaneous abortion, stillbirth, and infant mortality</article-title><source>Epidemiology</source><year>2010</year><volume>21</volume><fpage>797</fpage><lpage>804</lpage><pub-id pub-id-type="pmid">20864889</pub-id></element-citation></ref><ref id="b142"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Reddy</surname><given-names>E</given-names></name><name><surname>Shaw</surname><given-names>A</given-names></name><name><surname>Crump</surname><given-names>J</given-names></name></person-group><article-title>Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis</article-title><source>The Lancet. Infectious Diseases</source><year>2010</year><volume>10</volume><fpage>417</fpage><lpage>432</lpage><pub-id pub-id-type="pmid">20510282</pub-id></element-citation></ref><ref id="b143"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rein</surname><given-names>D</given-names></name><name><surname>Stevens</surname><given-names>G</given-names></name><name><surname>Theaker</surname><given-names>J</given-names></name><name><surname>Wittenborn</surname><given-names>J</given-names></name><name><surname>Wiersma</surname><given-names>S</given-names></name></person-group><article-title>The global burden of hepatitis E virus genotypes 1 and 2 in 2005</article-title><source>Hepatology</source><year>2012</year><volume>55</volume><fpage>988</fpage><lpage>997</lpage><pub-id pub-id-type="pmid">22121109</pub-id></element-citation></ref><ref id="b144"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rich-Edwards</surname><given-names>J</given-names></name><name><surname>Stampfer</surname><given-names>M</given-names></name><name><surname>Manson</surname><given-names>J</given-names></name><etal></etal></person-group><article-title>Birth weight and risk of cardiovascular disease in a cohort of women followed up since 1976</article-title><source>BMJ</source><year>1997</year><volume>315</volume><fpage>396</fpage><lpage>400</lpage><pub-id pub-id-type="pmid">9277603</pub-id></element-citation></ref><ref id="b145"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Roper</surname><given-names>M</given-names></name><name><surname>Vandelaer</surname><given-names>J</given-names></name><name><surname>Gasse</surname><given-names>F</given-names></name></person-group><article-title>Maternal and neonatal tetanus</article-title><source>Lancet</source><year>2007</year><volume>370</volume><fpage>1947</fpage><lpage>1959</lpage><pub-id pub-id-type="pmid">17854885</pub-id></element-citation></ref><ref id="b146"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Rosen</surname><given-names>S</given-names></name><name><surname>Vincent</surname><given-names>J</given-names></name></person-group><source>Household Water Resources and Rural Productivity in Sub-Saharan Africa: A Review of the Evidence</source><year>1999</year><publisher-loc>Cambridge, MA</publisher-loc><publisher-name>Harvard Institute for International Development</publisher-name></element-citation></ref><ref id="b147"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Rossi</surname><given-names>A</given-names></name><name><surname>D'Addario</surname><given-names>V</given-names></name></person-group><article-title>Maternal morbidity following a trial of labor after cesarean section vs elective repeat cesarean delivery: a systematic review with metaanalysis</article-title><source>American Journal of Obstetrics & Gynecology</source><year>2008</year><volume>199</volume><fpage>224</fpage><lpage>231</lpage><pub-id pub-id-type="pmid">18511018</pub-id></element-citation></ref><ref id="b148"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ruma</surname><given-names>M</given-names></name><name><surname>Boggess</surname><given-names>K</given-names></name><name><surname>Moss</surname><given-names>K</given-names></name><etal></etal></person-group><article-title>Maternal periodontal disease, systemic inflammation, and risk for preeclampsia</article-title><source>American Journal of Obstetrics and Gynecology</source><year>2008</year><volume>198</volume><fpage>389.e381</fpage><lpage>389.e385</lpage><pub-id pub-id-type="pmid">18295179</pub-id></element-citation></ref><ref id="b149"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Schieve</surname><given-names>L</given-names></name><name><surname>Handler</surname><given-names>A</given-names></name><name><surname>Hershow</surname><given-names>R</given-names></name><name><surname>Persky</surname><given-names>V</given-names></name><name><surname>Davis</surname><given-names>F</given-names></name></person-group><article-title>Urinary tract infection during pregnancy: its association with maternal morbidity and perinatal outcome</article-title><source>American Journal of Public Health</source><year>1994</year><volume>84</volume><fpage>405</fpage><lpage>410</lpage><pub-id pub-id-type="pmid">8129056</pub-id></element-citation></ref><ref id="b150"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Semba</surname><given-names>R</given-names></name><name><surname>de Pee</surname><given-names>S</given-names></name><name><surname>Kraemer</surname><given-names>K</given-names></name><etal></etal></person-group><article-title>Purchase of drinking water is associated with increased child morbidity and mortality among urban slum-dwelling families in Indonesia</article-title><source>International Journal of Hygiene and Environmental Health</source><year>2009</year><volume>21</volume><fpage>387</fpage><lpage>397</lpage><pub-id pub-id-type="pmid">18976955</pub-id></element-citation></ref><ref id="b151"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Semedo Leite</surname><given-names>T</given-names></name><name><surname>De</surname><given-names>CAD</given-names></name><name><surname>Viana</surname><given-names>J</given-names></name><name><surname>Nogueira</surname><given-names>R</given-names></name><name><surname>Lobo</surname><given-names>I</given-names></name></person-group><article-title>Listeria and yersinia infection in pregnancy: a case report and literature review</article-title><source>International Journal of Gynecology and Obstetrics</source><year>2012</year><volume>119</volume><fpage>S477</fpage></element-citation></ref><ref id="b152"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Semmelweis</surname><given-names>I</given-names></name></person-group><source>The Etiology, Concept and Prophylaxis of Childbed Fever</source><year>1983</year><publisher-loc>Madison, WI</publisher-loc><publisher-name>The University of Wisconsin Press</publisher-name></element-citation></ref><ref id="b153"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Seydel</surname><given-names>L</given-names></name><name><surname>Petelski</surname><given-names>A</given-names></name><name><surname>van Dam</surname><given-names>G</given-names></name><etal></etal></person-group><article-title>Association of in utero sensitization to Schistosoma haematobium with enhanced cord blood IgE and increased frequencies of CD5- B cells in African newborns</article-title><source>American Journal of Tropical Medicine and Hygiene</source><year>2012</year><volume>86</volume><fpage>613</fpage><lpage>619</lpage><pub-id pub-id-type="pmid">22492145</pub-id></element-citation></ref><ref id="b154"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Shirangi</surname><given-names>A</given-names></name><name><surname>Nieuwenhuijsen</surname><given-names>M</given-names></name><name><surname>Vienneau</surname><given-names>D</given-names></name><name><surname>Holman</surname><given-names>CD</given-names></name></person-group><article-title>Living near agricultural pesticide applications and the risk of adverse reproductive outcomes: a review of the literature</article-title><source>Paediatric and Perinatal Epidemiology</source><year>2011</year><volume>25</volume><fpage>172</fpage><lpage>191</lpage><pub-id pub-id-type="pmid">21281330</pub-id></element-citation></ref><ref id="b155"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Shulman</surname><given-names>C</given-names></name><name><surname>Dorman</surname><given-names>E</given-names></name><name><surname>Bulmer</surname><given-names>J</given-names></name></person-group><article-title>Malaria as a cause of severe anaemia in pregnancy</article-title><source>Lancet</source><year>2002</year><volume>360</volume><fpage>494</fpage><pub-id pub-id-type="pmid">12241758</pub-id></element-citation></ref><ref id="b156"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Siegrist</surname><given-names>D</given-names></name><name><surname>Siegrist-Obimpeh</surname><given-names>P</given-names></name></person-group><article-title>Schistosoma haematobium infection in pregnancy</article-title><source>Acta Tropica</source><year>1992</year><volume>50</volume><fpage>317</fpage><lpage>321</lpage><pub-id pub-id-type="pmid">1356302</pub-id></element-citation></ref><ref id="b157"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Singh</surname><given-names>J</given-names></name><name><surname>Bhoi</surname><given-names>S</given-names></name><name><surname>Gupta</surname><given-names>V</given-names></name><name><surname>Goel</surname><given-names>A</given-names></name></person-group><article-title>Clinical profile of venomous snake bites in north Indian Military Hospital</article-title><source>Journal of Emergencies, Trauma and Shock</source><year>2008</year><volume>1</volume><fpage>78</fpage><lpage>80</lpage></element-citation></ref><ref id="b158"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Smith</surname><given-names>JL</given-names></name></person-group><article-title>Foodborne infections during pregnancy</article-title><source>Journal of Food Protection</source><year>1999</year><volume>62</volume><fpage>818</fpage><lpage>829</lpage><pub-id pub-id-type="pmid">10419281</pub-id></element-citation></ref><ref id="b159"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Song</surname><given-names>T</given-names></name><name><surname>Cho</surname><given-names>H</given-names></name><name><surname>Kim</surname><given-names>J</given-names></name><etal></etal></person-group><article-title>Maternal height and the risk of cesarean delivery due to cephalopelvic disproportion in nulliparous women</article-title><source>Chonnam Medical Journal</source><year>2009</year><volume>45</volume><fpage>111</fpage><lpage>115</lpage></element-citation></ref><ref id="b160"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Southwick</surname><given-names>FS</given-names></name><name><surname>Purich</surname><given-names>DL</given-names></name></person-group><article-title>Intracellular pathogenesis of Listeriosis</article-title><source>New England Journal of Medicine</source><year>1996</year><volume>334</volume><fpage>770</fpage><lpage>777</lpage><pub-id pub-id-type="pmid">8592552</pub-id></element-citation></ref><ref id="b161"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Steketee</surname><given-names>RW</given-names></name><name><surname>Nahlen</surname><given-names>BL</given-names></name><name><surname>Parise</surname><given-names>ME</given-names></name><name><surname>Menendez</surname><given-names>C</given-names></name></person-group><article-title>The burden of malaria in pregnancy in malaria-endemic areas</article-title><source>American Journal of Tropical Medicine and Hygiene</source><year>2001</year><volume>64</volume><fpage>28</fpage><lpage>35</lpage><pub-id pub-id-type="pmid">11425175</pub-id></element-citation></ref><ref id="b162"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Susser</surname><given-names>M</given-names></name><name><surname>Susser</surname><given-names>E</given-names></name></person-group><article-title>Choosing a future for epidemiology: 1 Eras and paradigms</article-title><source>American Journal of Public Health</source><year>1996</year><volume>86</volume><fpage>668</fpage><lpage>673</lpage><pub-id pub-id-type="pmid">8629717</pub-id></element-citation></ref><ref id="b163"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Swai</surname><given-names>B</given-names></name><name><surname>Poggensee</surname><given-names>G</given-names></name><name><surname>Mtweve</surname><given-names>S</given-names></name><name><surname>Krantz</surname><given-names>I</given-names></name></person-group><article-title>Female genital schistosomiasis as an evidence of a neglected cause for reproductive ill-health: a retrospective histopathological study from Tanzania</article-title><source>BMC Infectious Diseases</source><year>2006</year><volume>6</volume><fpage>134</fpage><comment>doi:<ext-link ext-link-type="doi" xlink:href="10.1186/1471-2334-6-134">10.1186/1471-2334-6-134</ext-link></comment><pub-id pub-id-type="pmid">16928276</pub-id></element-citation></ref><ref id="b164"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tan</surname><given-names>P</given-names></name><name><surname>Soe</surname><given-names>M</given-names></name><name><surname>Si Lay</surname><given-names>K</given-names></name><etal></etal></person-group><article-title>Dengue infection and miscarriage: a prospective case control study</article-title><source>PLoS Neglected Tropical Diseases</source><year>2012</year><volume>6</volume><fpage>e1637</fpage><pub-id pub-id-type="pmid">22590658</pub-id></element-citation></ref><ref id="b165"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Thaddeus</surname><given-names>S</given-names></name><name><surname>Maine</surname><given-names>D</given-names></name></person-group><article-title>Too far to walk: maternal mortality in context</article-title><source>Social Science & Medicine</source><year>1994</year><volume>38</volume><fpage>1091</fpage><lpage>1110</lpage><pub-id pub-id-type="pmid">8042057</pub-id></element-citation></ref><ref id="b166"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Thatrimontrichai</surname><given-names>A</given-names></name><name><surname>Maneenil</surname><given-names>G</given-names></name></person-group><article-title>Neonatal melioidosis: systematic review of the literature</article-title><source>Pediatric Infectious Disease Journal</source><year>2012</year><volume>31</volume><fpage>1195</fpage><lpage>1197</lpage><pub-id pub-id-type="pmid">22739573</pub-id></element-citation></ref><ref id="b167"><element-citation publication-type="other"><collab>The United Nations</collab><year>2012</year><comment>The Future We Want: Outcome document adopted at Rio+20 <ext-link ext-link-type="uri" xlink:href="http://www.un.org/disabilities/documents/rio20_outcome_document_complete.pdf">http://www.un.org/disabilities/documents/rio20_outcome_document_complete.pdf</ext-link> (accessed 16 November 2012)</comment></element-citation></ref><ref id="b168"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Tsvieli</surname><given-names>O</given-names></name><name><surname>Sergienko</surname><given-names>R</given-names></name><name><surname>Sheiner</surname><given-names>E</given-names></name></person-group><article-title>Risk factors and perinatal outcome of pregnancies complicated with cephalopelvic disproportion: a population-based study</article-title><source>Archives of Gynecology and Obstetrics</source><year>2012</year><volume>285</volume><fpage>931</fpage><lpage>936</lpage><pub-id pub-id-type="pmid">21932085</pub-id></element-citation></ref><ref id="b169"><element-citation publication-type="other"><collab>UNICEF</collab><year>2012</year><comment>Delivery care: The challenge <ext-link ext-link-type="uri" xlink:href="http://www.childinfo.org/delivery_care.html">http://www.childinfo.org/delivery_care.html</ext-link> (accessed 31 December 2012)</comment></element-citation></ref><ref id="b170"><element-citation publication-type="book"><collab>UNICEF, WHO</collab><source>Drinking Water: Equity, Safety and Sustainability</source><year>2011</year><publisher-loc>New York</publisher-loc><publisher-name>UNICEF and World Health Organization</publisher-name></element-citation></ref><ref id="b171"><element-citation publication-type="book"><collab>UNICEF, WHO</collab><source>Progress on Drinking Water and Sanitation: 2012 Update</source><year>2012</year><publisher-loc>New York, NY</publisher-loc><publisher-name>UNICEF and World Health Organization</publisher-name></element-citation></ref><ref id="b172"><element-citation publication-type="book"><collab>United Nations General Assembly</collab><source>United Nations Millennium Declaration</source><year>2000</year><publisher-loc>New York</publisher-loc><publisher-name>UN</publisher-name></element-citation></ref><ref id="b173"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Vahter</surname><given-names>M</given-names></name><name><surname>Berglund</surname><given-names>M</given-names></name><name><surname>Åkesson</surname><given-names>A</given-names></name><name><surname>Lidén</surname><given-names>C</given-names></name></person-group><article-title>Metals and women's health</article-title><source>Environmental Research</source><year>2002</year><volume>88</volume><fpage>145</fpage><lpage>155</lpage><pub-id pub-id-type="pmid">12051792</pub-id></element-citation></ref><ref id="b174"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>van Eijk</surname><given-names>A</given-names></name><name><surname>Ayisi</surname><given-names>J</given-names></name><name><surname>ter Kuile</surname><given-names>F</given-names></name><etal></etal></person-group><article-title>Malaria and human immunodeficiency virus infection as risk factors for anemia in infants in Kisumu, western Kenya</article-title><source>American Journal of Tropical Medicine and Hygiene</source><year>2002</year><volume>67</volume><fpage>44</fpage><lpage>53</lpage><pub-id pub-id-type="pmid">12363063</pub-id></element-citation></ref><ref id="b175"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Velleman</surname><given-names>Y</given-names></name><name><surname>Mason</surname><given-names>E</given-names></name><name><surname>Graham</surname><given-names>W</given-names></name><etal></etal></person-group><article-title>From joint thinking to joint action: a call to action on improving water, sanitation and hygiene for maternal and newborn health</article-title><source>PLoS Medicine</source><year>2014</year><comment><ext-link ext-link-type="uri" xlink:href="http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001771">http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001771</ext-link></comment></element-citation></ref><ref id="b176"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Waage</surname><given-names>J</given-names></name><name><surname>Banerji</surname><given-names>R</given-names></name><name><surname>Campbell</surname><given-names>O</given-names></name><etal></etal></person-group><article-title>The Millennium Development Goals: a cross-sectoral analysis and principles for goal setting after 2015 Lancet and London International Development Centre Commission</article-title><source>The Lancet</source><year>2010</year><volume>376</volume><fpage>929</fpage></element-citation></ref><ref id="b177"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>Wagner</surname><given-names>E</given-names></name><name><surname>Lanoix</surname><given-names>J</given-names></name></person-group><source>Excreta Disposal for Rural Areas and Small Communities</source><year>1958</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="b178"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Waller</surname><given-names>K</given-names></name><name><surname>Swan</surname><given-names>S</given-names></name><name><surname>DeLorenze</surname><given-names>G</given-names></name><name><surname>Hopkins</surname><given-names>B</given-names></name></person-group><article-title>Trihalomethanes in drinking water and spontaneous abortion</article-title><source>Epidemiology</source><year>1998</year><volume>9</volume><fpage>134</fpage><lpage>140</lpage><pub-id pub-id-type="pmid">9504280</pub-id></element-citation></ref><ref id="b179"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Wasserheit</surname><given-names>J</given-names></name><name><surname>Harris</surname><given-names>J</given-names></name><name><surname>Chakraborty</surname><given-names>J</given-names></name><name><surname>Kay</surname><given-names>B</given-names></name><name><surname>Mason</surname><given-names>K</given-names></name></person-group><article-title>Reproductive tract infections in a family planning population in rural Bangladesh</article-title><source>Studies in Family Planning</source><year>1989</year><volume>20</volume><fpage>69</fpage><lpage>80</lpage><pub-id pub-id-type="pmid">2785722</pub-id></element-citation></ref><ref id="b180"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Watts</surname><given-names>C</given-names></name><name><surname>Cairncross</surname><given-names>S</given-names></name></person-group><article-title>Should the GBD risk factor rankings be used to guide policy?</article-title><source>The Lancet</source><year>2012</year><volume>380</volume><fpage>2060</fpage><lpage>2061</lpage></element-citation></ref><ref id="b181"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Weisman</surname><given-names>C</given-names></name></person-group><article-title>Changing definitions of women's heath: implications for health care and policy</article-title><source>Maternal & Child Health Journal</source><year>1997</year><volume>1</volume><fpage>179</fpage><lpage>189</lpage><pub-id pub-id-type="pmid">10728242</pub-id></element-citation></ref><ref id="b182"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Whincup</surname><given-names>P</given-names></name><name><surname>Kaye</surname><given-names>S</given-names></name><name><surname>Owen</surname><given-names>C</given-names></name><etal></etal></person-group><article-title>Birth weight and risk of type 2 diabetes: a systematic review</article-title><source>JAMA</source><year>2008</year><volume>300</volume><fpage>2886</fpage><lpage>2897</lpage><pub-id pub-id-type="pmid">19109117</pub-id></element-citation></ref><ref id="b183"><element-citation publication-type="book"><person-group person-group-type="author"><name><surname>White</surname><given-names>G</given-names></name><name><surname>Bradley</surname><given-names>D</given-names></name><name><surname>White</surname><given-names>A</given-names></name></person-group><source>Drawers of Water: Domestic Water Use in East Africa</source><year>1972</year><publisher-loc>Chicago</publisher-loc><publisher-name>University of Chicago Press</publisher-name></element-citation></ref><ref id="b184"><element-citation publication-type="book"><collab>World Health Organization</collab><source>UN-Water Global Annual Assessment of Sanitation and Drinking-Water (GLAAS) 2012 Report: The Challenge of Extending and Sustaining Services</source><year>2012</year><publisher-loc>Geneva</publisher-loc><publisher-name>WHO</publisher-name></element-citation></ref><ref id="b185"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Xiong</surname><given-names>X</given-names></name><name><surname>Buekens</surname><given-names>P</given-names></name><name><surname>Fraser</surname><given-names>WD</given-names></name><name><surname>Beck</surname><given-names>J</given-names></name><name><surname>Offenbacher</surname><given-names>S</given-names></name></person-group><article-title>Periodontal disease and adverse pregnancy outcomes: a systematic review</article-title><source>BJOG</source><year>2006</year><volume>113</volume><fpage>135</fpage><lpage>143</lpage><pub-id pub-id-type="pmid">16411989</pub-id></element-citation></ref><ref id="b186"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Yermachenko</surname><given-names>A</given-names></name><name><surname>Dvornyk</surname><given-names>V</given-names></name></person-group><article-title>Prenatal factors affecting the age at menarche</article-title><source>European Journal of Contraception and Reproductive Health Care</source><year>2013</year><volume>18</volume><fpage>S94</fpage></element-citation></ref><ref id="b187"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Younis</surname><given-names>N</given-names></name><name><surname>Khattab</surname><given-names>H</given-names></name><name><surname>Zurayk</surname><given-names>H</given-names></name><etal></etal></person-group><article-title>A community study of gynecological and related morbidities in rural Egypt</article-title><source>Studies in Family Planning</source><year>1993</year><volume>24</volume><fpage>175</fpage><lpage>186</lpage><pub-id pub-id-type="pmid">8351698</pub-id></element-citation></ref><ref id="b188"><element-citation publication-type="journal"><person-group person-group-type="author"><name><surname>Ziegelbauer</surname><given-names>K</given-names></name><name><surname>Speich</surname><given-names>B</given-names></name><name><surname>Mäusezahl</surname><given-names>D</given-names></name><etal></etal></person-group><article-title>Effect of sanitation on soil-transmitted helminth infection: systematic review and meta-analysis</article-title><source>PLoS Medicine</source><year>2012</year><volume>9</volume><fpage>e1001162</fpage><pub-id pub-id-type="pmid">22291577</pub-id></element-citation></ref></ref-list><sec sec-type="supplementary-material"><title>Supporting Information</title><p>Additional Supporting Information may be found in the online version of this article:</p><supplementary-material content-type="local-data" id="SD1"><caption><p><bold>Webtable S1</bold>. Overview of identified mechanisms linking reproductive and maternal health to WASH exposures and types of evidence identified.</p></caption><media mimetype="application" mime-subtype="pdf" xlink:href="tmi0020-0252-sd1.pdf" xlink:type="simple" id="d36e6861" position="anchor"></media></supplementary-material><supplementary-material content-type="local-data" id="SD2"><caption><p><bold>Webtable S2.</bold> WASH mechanisms linked with reproductive and maternal health for which we identified systematic or other evidence.</p></caption><media mimetype="application" mime-subtype="pdf" xlink:href="tmi0020-0252-sd2.pdf" xlink:type="simple" id="d36e6868" position="anchor"></media></supplementary-material></sec></back></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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