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Mortality Related to Acute Illness and Injury in Rural Uganda: Task Shifting to Improve Outcomes

Identifieur interne : 000B75 ( Pmc/Checkpoint ); précédent : 000B74; suivant : 000B76

Mortality Related to Acute Illness and Injury in Rural Uganda: Task Shifting to Improve Outcomes

Auteurs : Stacey Chamberlain [États-Unis] ; Uwe Stolz [États-Unis] ; Bradley Dreifuss [États-Unis] ; Sara W. Nelson [États-Unis] ; Heather Hammerstedt [États-Unis] ; Jovita Andinda [Ouganda] ; Samuel Maling [Ouganda] ; Mark Bisanzo [États-Unis]

Source :

RBID : PMC:4388510

Abstract

Background

Due to the dual critical shortages of acute care and healthcare workers in resource-limited settings, many people suffer or die from conditions that could be easily treated if existing resources were used in a more timely and effective manner. In order to address this preventable morbidity and mortality, a novel emergency midlevel provider training program was developed in rural Uganda. This is the first study that assesses this unique application of a task-shifting model to acute care by evaluating the outcomes of 10,105 patients.

Methods

Nurses participated in a two-year training program to become midlevel providers called Emergency Care Practitioners at a rural district hospital. This is a retrospective analysis of the Emergency Department’s quality assurance database, including three-day follow-up data. Case fatality rates (CFRs) are reported as the percentage of cases with a specific diagnosis that died within three days of their Emergency Department visit.

Findings

Overall, three-day mortality was 2.0%. The most common diagnoses of patients who died were malaria (n=60), pneumonia (n=51), malnutrition (n=21), and trauma (n=18). Overall and under-five CFRs were as follows: malaria, 2.0% and 1.9%; pneumonia, 5.5% and 4.1%; and trauma, 1.2% and 1.6%. Malnutrition-related fatality (all cases <18 years old) was 6.5% overall and 6.8% for under-fives.

Interpretation

This study describes the outcomes of emergency patients treated by midlevel providers in a resource-limited setting. Our fatality rates are lower than previously published regional rates. These findings suggest this model of task-shifting can be successfully applied to acute care in order to address the shortage of emergency care services in similar settings as part of an integrated approach to health systems strengthening.


Url:
DOI: 10.1371/journal.pone.0122559
PubMed: 25849960
PubMed Central: 4388510


Affiliations:


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PMC:4388510

Le document en format XML

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<p>Nurses participated in a two-year training program to become midlevel providers called Emergency Care Practitioners at a rural district hospital. This is a retrospective analysis of the Emergency Department’s quality assurance database, including three-day follow-up data. Case fatality rates (CFRs) are reported as the percentage of cases with a specific diagnosis that died within three days of their Emergency Department visit.</p>
</sec>
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<title>Findings</title>
<p>Overall, three-day mortality was 2.0%. The most common diagnoses of patients who died were malaria (n=60), pneumonia (n=51), malnutrition (n=21), and trauma (n=18). Overall and under-five CFRs were as follows: malaria, 2.0% and 1.9%; pneumonia, 5.5% and 4.1%; and trauma, 1.2% and 1.6%. Malnutrition-related fatality (all cases <18 years old) was 6.5% overall and 6.8% for under-fives.</p>
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<p>This study describes the outcomes of emergency patients treated by midlevel providers in a resource-limited setting. Our fatality rates are lower than previously published regional rates. These findings suggest this model of task-shifting can be successfully applied to acute care in order to address the shortage of emergency care services in similar settings as part of an integrated approach to health systems strengthening.</p>
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<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">PLoS One</journal-id>
<journal-id journal-id-type="iso-abbrev">PLoS ONE</journal-id>
<journal-id journal-id-type="publisher-id">plos</journal-id>
<journal-id journal-id-type="pmc">plosone</journal-id>
<journal-title-group>
<journal-title>PLoS ONE</journal-title>
</journal-title-group>
<issn pub-type="epub">1932-6203</issn>
<publisher>
<publisher-name>Public Library of Science</publisher-name>
<publisher-loc>San Francisco, CA USA</publisher-loc>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">25849960</article-id>
<article-id pub-id-type="pmc">4388510</article-id>
<article-id pub-id-type="doi">10.1371/journal.pone.0122559</article-id>
<article-id pub-id-type="publisher-id">PONE-D-14-18011</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Research Article</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Mortality Related to Acute Illness and Injury in Rural Uganda: Task Shifting to Improve Outcomes</article-title>
<alt-title alt-title-type="running-head">Task Shifting to Improve Outcomes in Acute Care Patients</alt-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Chamberlain</surname>
<given-names>Stacey</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff002">
<sup>2</sup>
</xref>
<xref rid="cor001" ref-type="corresp">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Stolz</surname>
<given-names>Uwe</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff003">
<sup>3</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Dreifuss</surname>
<given-names>Bradley</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff003">
<sup>3</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Nelson</surname>
<given-names>Sara W.</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff004">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hammerstedt</surname>
<given-names>Heather</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff005">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Andinda</surname>
<given-names>Jovita</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff006">
<sup>6</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Maling</surname>
<given-names>Samuel</given-names>
</name>
<xref ref-type="aff" rid="aff007">
<sup>7</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bisanzo</surname>
<given-names>Mark</given-names>
</name>
<xref ref-type="aff" rid="aff001">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aff008">
<sup>8</sup>
</xref>
</contrib>
</contrib-group>
<aff id="aff001">
<label>1</label>
<addr-line>Global Emergency Care Collaborative, Massachusetts, United States of America and Uganda</addr-line>
</aff>
<aff id="aff002">
<label>2</label>
<addr-line>Department of Emergency Medicine and Center for Global Health, University of Illinois at Chicago, Chicago, Illinois, United States of America</addr-line>
</aff>
<aff id="aff003">
<label>3</label>
<addr-line>Department of Emergency Medicine, University of Arizona, Tucson, Arizona, United States of America</addr-line>
</aff>
<aff id="aff004">
<label>4</label>
<addr-line>Department of Emergency Medicine, Maine Medical Center, Portland, Maine, United States of America</addr-line>
</aff>
<aff id="aff005">
<label>5</label>
<addr-line>Idaho Emergency Physicians, Boise, Idaho, United States of America</addr-line>
</aff>
<aff id="aff006">
<label>6</label>
<addr-line>Karoli Lwanga Hospital, Nyakibale, Uganda</addr-line>
</aff>
<aff id="aff007">
<label>7</label>
<addr-line>Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda</addr-line>
</aff>
<aff id="aff008">
<label>8</label>
<addr-line>Department of Emergency Medicine, University of Massachusetts, Worcester, Massachusetts, United States of America</addr-line>
</aff>
<contrib-group>
<contrib contrib-type="editor">
<name>
<surname>Price</surname>
<given-names>Matt A</given-names>
</name>
<role>Academic Editor</role>
<xref ref-type="aff" rid="edit1"></xref>
</contrib>
</contrib-group>
<aff id="edit1">
<addr-line>International AIDS Vaccine Initiative, UNITED STATES</addr-line>
</aff>
<author-notes>
<fn fn-type="conflict" id="coi001">
<p>
<bold>Competing Interests: </bold>
The authors have declared that no competing interests exist.</p>
</fn>
<fn fn-type="con" id="contrib001">
<p>Conceived and designed the experiments: SC US BD HH SM MB. Performed the experiments: BD JA MB. Analyzed the data: SC US MB. Contributed reagents/materials/analysis tools: US. Wrote the paper: SC US BD SN HH JA SM MB.</p>
</fn>
<corresp id="cor001">* E-mail:
<email>chamberlain.stacey@gmail.com</email>
</corresp>
</author-notes>
<pub-date pub-type="epub">
<day>7</day>
<month>4</month>
<year>2015</year>
</pub-date>
<pub-date pub-type="collection">
<year>2015</year>
</pub-date>
<volume>10</volume>
<issue>4</issue>
<elocation-id>e0122559</elocation-id>
<history>
<date date-type="received">
<day>29</day>
<month>4</month>
<year>2014</year>
</date>
<date date-type="accepted">
<day>23</day>
<month>2</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-year>2015</copyright-year>
<copyright-holder>Chamberlain et al</copyright-holder>
<license xlink:href="http://creativecommons.org/licenses/by/4.0/">
<license-p>This is an open access article distributed under the terms of the
<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</ext-link>
, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited</license-p>
</license>
</permissions>
<self-uri content-type="pdf" xlink:type="simple" xlink:href="pone.0122559.pdf"></self-uri>
<abstract>
<sec id="sec001">
<title>Background</title>
<p>Due to the dual critical shortages of acute care
<italic>and</italic>
healthcare workers in resource-limited settings, many people suffer or die from conditions that could be easily treated if existing resources were used in a more timely and effective manner. In order to address this preventable morbidity and mortality, a novel emergency midlevel provider training program was developed in rural Uganda. This is the first study that assesses this unique application of a task-shifting model to acute care by evaluating the outcomes of 10,105 patients.</p>
</sec>
<sec id="sec002">
<title>Methods</title>
<p>Nurses participated in a two-year training program to become midlevel providers called Emergency Care Practitioners at a rural district hospital. This is a retrospective analysis of the Emergency Department’s quality assurance database, including three-day follow-up data. Case fatality rates (CFRs) are reported as the percentage of cases with a specific diagnosis that died within three days of their Emergency Department visit.</p>
</sec>
<sec id="sec003">
<title>Findings</title>
<p>Overall, three-day mortality was 2.0%. The most common diagnoses of patients who died were malaria (n=60), pneumonia (n=51), malnutrition (n=21), and trauma (n=18). Overall and under-five CFRs were as follows: malaria, 2.0% and 1.9%; pneumonia, 5.5% and 4.1%; and trauma, 1.2% and 1.6%. Malnutrition-related fatality (all cases <18 years old) was 6.5% overall and 6.8% for under-fives.</p>
</sec>
<sec id="sec004">
<title>Interpretation</title>
<p>This study describes the outcomes of emergency patients treated by midlevel providers in a resource-limited setting. Our fatality rates are lower than previously published regional rates. These findings suggest this model of task-shifting can be successfully applied to acute care in order to address the shortage of emergency care services in similar settings as part of an integrated approach to health systems strengthening.</p>
</sec>
</abstract>
<funding-group>
<funding-statement>Global Emergency Care Collaborative (GECC) is a non-profit charitable organization registered in the United States and Uganda, which is funded through private non-corporate, non-governmental donations. GECC was responsible for providing partial salary support for the Emergency Care Practitioners who were the health professionals who cared for emergency patients in this study. Additionally, GECC paid stipends for volunteer research assistants and an onsite Program Director. None of the authors of this study have received any financial compensation for activities related to this study.</funding-statement>
</funding-group>
<counts>
<fig-count count="0"></fig-count>
<table-count count="4"></table-count>
<page-count count="11"></page-count>
</counts>
<custom-meta-group>
<custom-meta id="data-availability">
<meta-name>Data Availability</meta-name>
<meta-value>All relevant data are within the paper and its Supporting Information files.</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
<notes>
<title>Data Availability</title>
<p>All relevant data are within the paper and its Supporting Information files.</p>
</notes>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>Ouganda</li>
<li>États-Unis</li>
</country>
<region>
<li>Arizona</li>
<li>Idaho</li>
<li>Illinois</li>
<li>Maine (État)</li>
<li>Massachusetts</li>
</region>
<settlement>
<li>Amherst (Massachusetts)</li>
<li>Chicago</li>
</settlement>
<orgName>
<li>Université de l'Illinois à Chicago</li>
<li>Université du Massachusetts</li>
</orgName>
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<tree>
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<region name="Illinois">
<name sortKey="Chamberlain, Stacey" sort="Chamberlain, Stacey" uniqKey="Chamberlain S" first="Stacey" last="Chamberlain">Stacey Chamberlain</name>
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<name sortKey="Bisanzo, Mark" sort="Bisanzo, Mark" uniqKey="Bisanzo M" first="Mark" last="Bisanzo">Mark Bisanzo</name>
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<name sortKey="Hammerstedt, Heather" sort="Hammerstedt, Heather" uniqKey="Hammerstedt H" first="Heather" last="Hammerstedt">Heather Hammerstedt</name>
<name sortKey="Nelson, Sara W" sort="Nelson, Sara W" uniqKey="Nelson S" first="Sara W." last="Nelson">Sara W. Nelson</name>
<name sortKey="Stolz, Uwe" sort="Stolz, Uwe" uniqKey="Stolz U" first="Uwe" last="Stolz">Uwe Stolz</name>
</country>
<country name="Ouganda">
<noRegion>
<name sortKey="Andinda, Jovita" sort="Andinda, Jovita" uniqKey="Andinda J" first="Jovita" last="Andinda">Jovita Andinda</name>
</noRegion>
<name sortKey="Maling, Samuel" sort="Maling, Samuel" uniqKey="Maling S" first="Samuel" last="Maling">Samuel Maling</name>
</country>
</tree>
</affiliations>
</record>

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