Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study.
Identifieur interne : 003B79 ( Ncbi/Merge ); précédent : 003B78; suivant : 003B80Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study.
Auteurs : Tulio De Oliveira [Afrique du Sud] ; Ayesha B M. Kharsany [Afrique du Sud] ; Tiago Gr F [Afrique du Sud] ; Cherie Cawood [Afrique du Sud] ; David Khanyile [Afrique du Sud] ; Anneke Grobler [Afrique du Sud] ; Adrian Puren [Afrique du Sud] ; Savathree Madurai [Afrique du Sud] ; Cheryl Baxter [Afrique du Sud] ; Quarraisha Abdool Karim [États-Unis] ; Salim S Abdool Karim [États-Unis]Source :
- The lancet. HIV [ 2352-3018 ] ; 2017.
Descripteurs français
- KwdFr :
- Adolescent, Adulte, Adulte d'âge moyen, Anticorps anti-VIH (sang), Caractéristiques familiales, Charge virale, Comportement sexuel, Enquêtes et questionnaires, Facteurs de risque, Facteurs sexuels, Femelle, Génotype, Humains, Infections à VIH (immunologie), Infections à VIH (transmission), Infections à VIH (virologie), Infections à VIH (épidémiologie), Jeune adulte, Partenaire sexuel, Phylogénie, Prévalence, République d'Afrique du Sud (épidémiologie), Santé en zone rurale, VIH (Virus de l'Immunodéficience Humaine) (immunologie), VIH (Virus de l'Immunodéficience Humaine) (isolement et purification), Études transversales.
- MESH :
- immunologie : Infections à VIH, VIH (Virus de l'Immunodéficience Humaine).
- isolement et purification : VIH (Virus de l'Immunodéficience Humaine).
- sang : Anticorps anti-VIH.
- virologie : Infections à VIH.
- épidémiologie : Infections à VIH, République d'Afrique du Sud.
- Adolescent, Adulte, Adulte d'âge moyen, Caractéristiques familiales, Charge virale, Comportement sexuel, Enquêtes et questionnaires, Facteurs de risque, Facteurs sexuels, Femelle, Génotype, Humains, Jeune adulte, Partenaire sexuel, Phylogénie, Prévalence, Santé en zone rurale, Études transversales.
English descriptors
- KwdEn :
- Adolescent, Adult, Cross-Sectional Studies, Family Characteristics, Female, Genotype, HIV (immunology), HIV (isolation & purification), HIV Antibodies (blood), HIV Infections (epidemiology), HIV Infections (immunology), HIV Infections (transmission), HIV Infections (virology), Humans, Middle Aged, Phylogeny, Prevalence, Risk Factors, Rural Health, Sex Factors, Sexual Behavior, Sexual Partners, South Africa (epidemiology), Surveys and Questionnaires, Viral Load, Young Adult.
- MESH :
- chemical , blood : HIV Antibodies.
- epidemiology : HIV Infections, South Africa.
- immunology : HIV, HIV Infections.
- isolation & purification : HIV.
- transmission : HIV Infections.
- virology : HIV Infections.
- Adolescent, Adult, Cross-Sectional Studies, Family Characteristics, Female, Genotype, Humans, Middle Aged, Phylogeny, Prevalence, Risk Factors, Rural Health, Sex Factors, Sexual Behavior, Sexual Partners, Surveys and Questionnaires, Viral Load, Young Adult.
Abstract
The incidence of HIV infection in young women in Africa is very high. We did a large-scale community-wide phylogenetic study to examine the underlying HIV transmission dynamics and the source and consequences of high rates of HIV infection in young women in South Africa.
DOI: 10.1016/S2352-3018(16)30186-2
PubMed: 27914874
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pubmed:27914874Le document en format XML
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University of KwaZulu-Natal, Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Karim, Quarraisha Abdool" sort="Karim, Quarraisha Abdool" uniqKey="Karim Q" first="Quarraisha Abdool" last="Karim">Quarraisha Abdool Karim</name><affiliation wicri:level="2"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Karim, Salim S Abdool" sort="Karim, Salim S Abdool" uniqKey="Karim S" first="Salim S Abdool" last="Karim">Salim S Abdool Karim</name><affiliation wicri:level="2"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; 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University of KwaZulu-Natal, Durban, South Africa; Africa Centre for Population Health, Hlabisa, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Africa Centre for Population Health, Hlabisa</wicri:regionArea><wicri:noRegion>Hlabisa</wicri:noRegion></affiliation></author><author><name sortKey="Kharsany, Ayesha B M" sort="Kharsany, Ayesha B M" uniqKey="Kharsany A" first="Ayesha B M" last="Kharsany">Ayesha B M. Kharsany</name><affiliation wicri:level="1"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa. Electronic address: ayesha.kharsany@caprisa.org.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Gr F, Tiago" sort="Gr F, Tiago" uniqKey="Gr F T" first="Tiago" last="Gr F">Tiago Gr F</name><affiliation wicri:level="1"><nlm:affiliation>University of KwaZulu-Natal, Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>University of KwaZulu-Natal, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Cawood, Cherie" sort="Cawood, Cherie" uniqKey="Cawood C" first="Cherie" last="Cawood">Cherie Cawood</name><affiliation wicri:level="1"><nlm:affiliation>Epicentre, Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Epicentre, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Khanyile, David" sort="Khanyile, David" uniqKey="Khanyile D" first="David" last="Khanyile">David Khanyile</name><affiliation wicri:level="1"><nlm:affiliation>Epicentre, Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Epicentre, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Grobler, Anneke" sort="Grobler, Anneke" uniqKey="Grobler A" first="Anneke" last="Grobler">Anneke Grobler</name><affiliation wicri:level="1"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Puren, Adrian" sort="Puren, Adrian" uniqKey="Puren A" first="Adrian" last="Puren">Adrian Puren</name><affiliation wicri:level="1"><nlm:affiliation>National Institute for Communicable Diseases, Johannesburg, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>National Institute for Communicable Diseases, Johannesburg</wicri:regionArea><wicri:noRegion>Johannesburg</wicri:noRegion></affiliation></author><author><name sortKey="Madurai, Savathree" sort="Madurai, Savathree" uniqKey="Madurai S" first="Savathree" last="Madurai">Savathree Madurai</name><affiliation wicri:level="1"><nlm:affiliation>Global Clinical and Virology Laboratory, Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Global Clinical and Virology Laboratory, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Baxter, Cheryl" sort="Baxter, Cheryl" uniqKey="Baxter C" first="Cheryl" last="Baxter">Cheryl Baxter</name><affiliation wicri:level="1"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban</wicri:regionArea><wicri:noRegion>Durban</wicri:noRegion></affiliation></author><author><name sortKey="Karim, Quarraisha Abdool" sort="Karim, Quarraisha Abdool" uniqKey="Karim Q" first="Quarraisha Abdool" last="Karim">Quarraisha Abdool Karim</name><affiliation wicri:level="2"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author><author><name sortKey="Karim, Salim S Abdool" sort="Karim, Salim S Abdool" uniqKey="Karim S" first="Salim S Abdool" last="Karim">Salim S Abdool Karim</name><affiliation wicri:level="2"><nlm:affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region></placeName></affiliation></author></analytic><series><title level="j">The lancet. HIV</title><idno type="eISSN">2352-3018</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Cross-Sectional Studies</term><term>Family Characteristics</term><term>Female</term><term>Genotype</term><term>HIV (immunology)</term><term>HIV (isolation & purification)</term><term>HIV Antibodies (blood)</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (immunology)</term><term>HIV Infections (transmission)</term><term>HIV Infections (virology)</term><term>Humans</term><term>Middle Aged</term><term>Phylogeny</term><term>Prevalence</term><term>Risk Factors</term><term>Rural Health</term><term>Sex Factors</term><term>Sexual Behavior</term><term>Sexual Partners</term><term>South Africa (epidemiology)</term><term>Surveys and Questionnaires</term><term>Viral Load</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Anticorps anti-VIH (sang)</term><term>Caractéristiques familiales</term><term>Charge virale</term><term>Comportement sexuel</term><term>Enquêtes et questionnaires</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Génotype</term><term>Humains</term><term>Infections à VIH (immunologie)</term><term>Infections à VIH (transmission)</term><term>Infections à VIH (virologie)</term><term>Infections à VIH (épidémiologie)</term><term>Jeune adulte</term><term>Partenaire sexuel</term><term>Phylogénie</term><term>Prévalence</term><term>République d'Afrique du Sud (épidémiologie)</term><term>Santé en zone rurale</term><term>VIH (Virus de l'Immunodéficience Humaine) (immunologie)</term><term>VIH (Virus de l'Immunodéficience Humaine) (isolement et purification)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>HIV Antibodies</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term><term>South Africa</term></keywords><keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Infections à VIH</term><term>VIH (Virus de l'Immunodéficience Humaine)</term></keywords><keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>HIV</term><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>HIV</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>VIH (Virus de l'Immunodéficience Humaine)</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Anticorps anti-VIH</term></keywords><keywords scheme="MESH" qualifier="transmission" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term><term>République d'Afrique du Sud</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Cross-Sectional Studies</term><term>Family Characteristics</term><term>Female</term><term>Genotype</term><term>Humans</term><term>Middle Aged</term><term>Phylogeny</term><term>Prevalence</term><term>Risk Factors</term><term>Rural Health</term><term>Sex Factors</term><term>Sexual Behavior</term><term>Sexual Partners</term><term>Surveys and Questionnaires</term><term>Viral Load</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Caractéristiques familiales</term><term>Charge virale</term><term>Comportement sexuel</term><term>Enquêtes et questionnaires</term><term>Facteurs de risque</term><term>Facteurs sexuels</term><term>Femelle</term><term>Génotype</term><term>Humains</term><term>Jeune adulte</term><term>Partenaire sexuel</term><term>Phylogénie</term><term>Prévalence</term><term>Santé en zone rurale</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The incidence of HIV infection in young women in Africa is very high. We did a large-scale community-wide phylogenetic study to examine the underlying HIV transmission dynamics and the source and consequences of high rates of HIV infection in young women in South Africa.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27914874</PMID><DateCreated><Year>2016</Year><Month>12</Month><Day>04</Day></DateCreated><DateCompleted><Year>2017</Year><Month>07</Month><Day>27</Day></DateCompleted><DateRevised><Year>2017</Year><Month>07</Month><Day>27</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">2352-3018</ISSN><JournalIssue CitedMedium="Internet"><Volume>4</Volume><Issue>1</Issue><PubDate><Year>2017</Year><Month>Jan</Month></PubDate></JournalIssue><Title>The lancet. HIV</Title><ISOAbbreviation>Lancet HIV</ISOAbbreviation></Journal><ArticleTitle>Transmission networks and risk of HIV infection in KwaZulu-Natal, South Africa: a community-wide phylogenetic study.</ArticleTitle><Pagination><MedlinePgn>e41-e50</MedlinePgn></Pagination><ELocationID EIdType="pii" ValidYN="Y">S2352-3018(16)30186-2</ELocationID><ELocationID EIdType="doi" ValidYN="Y">10.1016/S2352-3018(16)30186-2</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">The incidence of HIV infection in young women in Africa is very high. We did a large-scale community-wide phylogenetic study to examine the underlying HIV transmission dynamics and the source and consequences of high rates of HIV infection in young women in South Africa.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">We did a cross-sectional household survey of randomly selected individuals aged 15-49 years in two neighbouring subdistricts (one urban and one rural) with a high burden of HIV infection in KwaZulu-Natal, South Africa. Participants completed structured questionnaires that captured general demographic, socioeconomic, psychosocial, and behavioural data. Peripheral blood samples were obtained for HIV antibody testing. Samples with HIV RNA viral load greater than 1000 copies per mL were selected for genotyping. We constructed a phylogenetic tree to identify clusters of linked infections (defined as two or more sequences with bootstrap or posterior support ≥90% and genetic distance ≤4·5%).</AbstractText><AbstractText Label="FINDINGS" NlmCategory="RESULTS">From June 11, 2014, to June 22, 2015, we enrolled 9812 participants, 3969 of whom tested HIV positive. HIV prevalence (weighted) was 59·8% in 2835 women aged 25-40 years, 40·3% in 1548 men aged 25-40 years, 22·3% in 2224 women younger than 25 years, and 7·6% in 1472 men younger than 25 years. HIV genotyping was done in 1589 individuals with a viral load of more than 1000 copies per mL. In 90 transmission clusters, 123 women were linked to 103 men. Of 60 possible phylogenetically linked pairings with the 43 women younger than 25 years, 18 (30·0%) probable male partners were younger than 25 years, 37 (61·7%) were aged 25-40 years, and five (8·3%) were aged 41-49 years: mean age difference 8·7 years (95% CI 6·8-10·6; p<0·0001). For the 92 possible phylogenetically linked pairings with the 56 women aged 25-40 years, the age difference dropped to 1·1 years (95% CI -0·6 to 2·8; p=0·111). 16 (39·0%) of 41 probable male partners linked to women younger than 25 years were also linked to women aged 25-40 years. Of 79 men (mean age 31·5 years) linked to women younger than 40 years, 62 (78·5%) were unaware of their HIV-positive status, 76 (96·2%) were not on antiretroviral therapy, and 29 (36·7%) had viral loads of more than 50 000 copies per mL.</AbstractText><AbstractText Label="INTERPRETATION" NlmCategory="CONCLUSIONS">Sexual partnering between young women and older men, who might have acquired HIV from women of similar age, is a key feature of the sexual networks driving transmission. Expansion of treatment and combination prevention strategies that include interventions to address age-disparate sexual partnering is crucial to reducing HIV incidence and enabling Africa to reach the goal of ending AIDS as a public health threat.</AbstractText><AbstractText Label="FUNDING" NlmCategory="BACKGROUND">President's Emergency Program for AIDS Relief, US Centers for Disease Control and Prevention, South African Medical Research Council, and MAC AIDS Fund.</AbstractText><CopyrightInformation>Copyright © 2017 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>de Oliveira</LastName><ForeName>Tulio</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Africa Centre for Population Health, Hlabisa, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Kharsany</LastName><ForeName>Ayesha B M</ForeName><Initials>AB</Initials><AffiliationInfo><Affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa. Electronic address: ayesha.kharsany@caprisa.org.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gräf</LastName><ForeName>Tiago</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>University of KwaZulu-Natal, Durban, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cawood</LastName><ForeName>Cherie</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Epicentre, Durban, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Khanyile</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Epicentre, Durban, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Grobler</LastName><ForeName>Anneke</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Puren</LastName><ForeName>Adrian</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>National Institute for Communicable Diseases, Johannesburg, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Madurai</LastName><ForeName>Savathree</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Global Clinical and Virology Laboratory, Durban, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Baxter</LastName><ForeName>Cheryl</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karim</LastName><ForeName>Quarraisha Abdool</ForeName><Initials>QA</Initials><AffiliationInfo><Affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Karim</LastName><ForeName>Salim S Abdool</ForeName><Initials>SS</Initials><AffiliationInfo><Affiliation>Centre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; University of KwaZulu-Natal, Durban, South Africa; Department of Epidemiology, Columbia University, New York, NY, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 HD083343</GrantID><Acronym>HD</Acronym><Agency>NICHD NIH HHS</Agency><Country>United States</Country></Grant><Grant><GrantID>U2G GH000372</GrantID><Acronym>GH</Acronym><Agency>CGH CDC HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2016</Year><Month>12</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Lancet HIV</MedlineTA><NlmUniqueID>101645355</NlmUniqueID><ISSNLinking>2352-3018</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015483">HIV Antibodies</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><CitationSubset>X</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>BMC Bioinformatics. 2013 Nov 06;14:317</RefSource><PMID Version="1">24191891</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Acquir Immune Defic Syndr. 2014 Aug 1;66(4):443-51</RefSource><PMID Version="1">24815854</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2010 Mar 10;5(3):e9490</RefSource><PMID Version="1">20224823</PMID></CommentsCorrections><CommentsCorrections 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Version="1">20154009</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Database (Oxford). 2014 Feb 06;2014:bat082</RefSource><PMID Version="1">24504151</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Acquir Immune Defic Syndr. 2014 Oct 1;67(2):181-95</RefSource><PMID Version="1">24977473</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Mol Evol. 1994 Sep;39(3):306-14</RefSource><PMID Version="1">7932792</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>BMC Public Health. 2015 Nov 20;15:1149</RefSource><PMID Version="1">26588902</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional 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Sud</li><li>États-Unis</li></country><region><li>État de New York</li></region></list><tree><country name="Afrique du Sud"><noRegion><name sortKey="De Oliveira, Tulio" sort="De Oliveira, Tulio" uniqKey="De Oliveira T" first="Tulio" last="De Oliveira">Tulio De Oliveira</name></noRegion><name sortKey="Baxter, Cheryl" sort="Baxter, Cheryl" uniqKey="Baxter C" first="Cheryl" last="Baxter">Cheryl Baxter</name><name sortKey="Cawood, Cherie" sort="Cawood, Cherie" uniqKey="Cawood C" first="Cherie" last="Cawood">Cherie Cawood</name><name sortKey="Gr F, Tiago" sort="Gr F, Tiago" uniqKey="Gr F T" first="Tiago" last="Gr F">Tiago Gr F</name><name sortKey="Grobler, Anneke" sort="Grobler, Anneke" uniqKey="Grobler A" first="Anneke" last="Grobler">Anneke Grobler</name><name sortKey="Khanyile, David" sort="Khanyile, David" uniqKey="Khanyile D" first="David" last="Khanyile">David Khanyile</name><name sortKey="Kharsany, Ayesha B M" sort="Kharsany, Ayesha B M" uniqKey="Kharsany A" first="Ayesha B M" last="Kharsany">Ayesha B M. Kharsany</name><name sortKey="Madurai, Savathree" sort="Madurai, Savathree" uniqKey="Madurai S" first="Savathree" last="Madurai">Savathree Madurai</name><name sortKey="Puren, Adrian" sort="Puren, Adrian" uniqKey="Puren A" first="Adrian" last="Puren">Adrian Puren</name></country><country name="États-Unis"><region name="État de New York"><name sortKey="Karim, Quarraisha Abdool" sort="Karim, Quarraisha Abdool" uniqKey="Karim Q" first="Quarraisha Abdool" last="Karim">Quarraisha Abdool Karim</name></region><name sortKey="Karim, Salim S Abdool" sort="Karim, Salim S Abdool" uniqKey="Karim S" first="Salim S Abdool" last="Karim">Salim S Abdool Karim</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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