Potential Impact of Co-Infections and Co-Morbidities Prevalent in Africa on Influenza Severity and Frequency: A Systematic Review
Identifieur interne : 003129 ( Ncbi/Merge ); précédent : 003128; suivant : 003130Potential Impact of Co-Infections and Co-Morbidities Prevalent in Africa on Influenza Severity and Frequency: A Systematic Review
Auteurs : Adam L. Cohen [États-Unis, Afrique du Sud] ; Meredith Mcmorrow [États-Unis] ; Sibongile Walaza [Afrique du Sud] ; Cheryl Cohen [Afrique du Sud] ; Stefano Tempia [États-Unis, Afrique du Sud] ; Marissa Alexander-Scott [États-Unis] ; Marc-Alain Widdowson [États-Unis]Source :
- PLoS ONE [ 1932-6203 ] ; 2015.
Abstract
Infectious diseases and underlying medical conditions common to Africa may affect influenza frequency and severity. We conducted a systematic review of published studies on influenza and the following co-infections or co-morbidities that are prevalent in Africa: dengue, malaria, measles, meningococcus,
Url:
DOI: 10.1371/journal.pone.0128580
PubMed: 26068416
PubMed Central: 4466242
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Adam L" uniqKey="Cohen A" first="Adam L." last="Cohen">Adam L. 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America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Influenza Program, Centers for Disease Control and Prevention—South Africa, Pretoria, South Africa</addr-line></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Influenza Program, Centers for Disease Control and Prevention—South Africa, Pretoria</wicri:regionArea><wicri:noRegion>Pretoria</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, Sandringham, South Africa</addr-line></nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, Sandringham</wicri:regionArea><wicri:noRegion>Sandringham</wicri:noRegion></affiliation></author><author><name sortKey="Alexander Scott, Marissa" sort="Alexander Scott, Marissa" uniqKey="Alexander Scott M" first="Marissa" last="Alexander-Scott">Marissa Alexander-Scott</name><affiliation wicri:level="2"><nlm:aff id="aff006"><addr-line>Division of Applied Research and Technology (DART), National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, Cincinnati, Ohio, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Division of Applied Research and Technology (DART), National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, Cincinnati, Ohio</wicri:regionArea><placeName><region type="state">Ohio</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="aff007"><addr-line>University of Illinois, Springfield, Illinois, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>University of Illinois, Springfield, Illinois</wicri:regionArea><placeName><region type="state">Illinois</region></placeName></affiliation></author><author><name sortKey="Widdowson, Marc Alain" sort="Widdowson, Marc Alain" uniqKey="Widdowson M" first="Marc-Alain" last="Widdowson">Marc-Alain Widdowson</name><affiliation wicri:level="2"><nlm:aff id="aff001"><addr-line>Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America</addr-line></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia</wicri:regionArea><placeName><region type="state">Géorgie (États-Unis)</region></placeName></affiliation></author></analytic><series><title level="j">PLoS ONE</title><idno type="eISSN">1932-6203</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Infectious diseases and underlying medical conditions common to Africa may affect influenza frequency and severity. We conducted a systematic review of published studies on influenza and the following co-infections or co-morbidities that are prevalent in Africa: dengue, malaria, measles, meningococcus, <italic>Pneumocystis jirovecii</italic> pneumonia (PCP), hemoglobinopathies, and malnutrition. Articles were identified except for influenza and PCP. Very few studies were from Africa. Sickle cell disease, dengue, and measles co-infection were found to increase the severity of influenza disease, though this is based on few studies of dengue and measles and the measles study was of low quality. The frequency of influenza was increased among patients with sickle cell disease. Influenza infection increased the frequency of meningococcal disease. Studies on malaria and malnutrition found mixed results. Age-adjusted morbidity and mortality from influenza may be more common in Africa because infections and diseases common in the region lead to more severe outcomes and increase the influenza burden. However, gaps exist in our knowledge about these interactions.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Gessner, Bd" uniqKey="Gessner B">BD Gessner</name></author><author><name sortKey="Shindo, N" uniqKey="Shindo N">N Shindo</name></author><author><name sortKey="Briand, S" uniqKey="Briand S">S Briand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yazdanbakhsh, M" uniqKey="Yazdanbakhsh M">M Yazdanbakhsh</name></author><author><name sortKey="Kremsner, Pg" uniqKey="Kremsner P">PG Kremsner</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Radin, Jm" uniqKey="Radin J">JM Radin</name></author><author><name sortKey="Katz, Ma" uniqKey="Katz M">MA Katz</name></author><author><name sortKey="Tempia, S" uniqKey="Tempia S">S Tempia</name></author><author><name sortKey="Talla, Nzussouo N" uniqKey="Talla N">Nzussouo N 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<front><journal-meta><journal-id journal-id-type="nlm-ta">PLoS One</journal-id><journal-id journal-id-type="iso-abbrev">PLoS ONE</journal-id><journal-id journal-id-type="publisher-id">plos</journal-id><journal-id journal-id-type="pmc">plosone</journal-id><journal-title-group><journal-title>PLoS ONE</journal-title></journal-title-group><issn pub-type="epub">1932-6203</issn><publisher><publisher-name>Public Library of Science</publisher-name><publisher-loc>San Francisco, CA USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26068416</article-id><article-id pub-id-type="pmc">4466242</article-id><article-id pub-id-type="doi">10.1371/journal.pone.0128580</article-id><article-id pub-id-type="publisher-id">PONE-D-15-04296</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Potential Impact of Co-Infections and Co-Morbidities Prevalent in Africa on Influenza Severity and Frequency: A Systematic Review</article-title><alt-title alt-title-type="running-head">Review of Influenza Co-Infection in Africa</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Cohen</surname><given-names>Adam L.</given-names></name><xref ref-type="aff" rid="aff001"><sup>1</sup></xref><xref ref-type="aff" rid="aff002"><sup>2</sup></xref><xref ref-type="aff" rid="aff003"><sup>3</sup></xref><xref rid="cor001" ref-type="corresp">*</xref></contrib><contrib contrib-type="author"><name><surname>McMorrow</surname><given-names>Meredith</given-names></name><xref ref-type="aff" rid="aff001"><sup>1</sup></xref><xref ref-type="aff" rid="aff003"><sup>3</sup></xref></contrib><contrib contrib-type="author"><name><surname>Walaza</surname><given-names>Sibongile</given-names></name><xref ref-type="aff" rid="aff004"><sup>4</sup></xref><xref ref-type="aff" rid="aff005"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Cohen</surname><given-names>Cheryl</given-names></name><xref ref-type="aff" rid="aff004"><sup>4</sup></xref><xref ref-type="aff" rid="aff005"><sup>5</sup></xref></contrib><contrib contrib-type="author"><name><surname>Tempia</surname><given-names>Stefano</given-names></name><xref ref-type="aff" rid="aff001"><sup>1</sup></xref><xref ref-type="aff" rid="aff002"><sup>2</sup></xref><xref ref-type="aff" rid="aff004"><sup>4</sup></xref></contrib><contrib contrib-type="author"><name><surname>Alexander-Scott</surname><given-names>Marissa</given-names></name><xref ref-type="aff" rid="aff006"><sup>6</sup></xref><xref ref-type="aff" rid="aff007"><sup>7</sup></xref></contrib><contrib contrib-type="author"><name><surname>Widdowson</surname><given-names>Marc-Alain</given-names></name><xref ref-type="aff" rid="aff001"><sup>1</sup></xref></contrib></contrib-group><aff id="aff001"><label>1</label><addr-line>Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America</addr-line></aff><aff id="aff002"><label>2</label><addr-line>Influenza Program, Centers for Disease Control and Prevention—South Africa, Pretoria, South Africa</addr-line></aff><aff id="aff003"><label>3</label><addr-line>United States Public Health Service, Rockville, Maryland, United States of America</addr-line></aff><aff id="aff004"><label>4</label><addr-line>Centre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases, Sandringham, South Africa</addr-line></aff><aff id="aff005"><label>5</label><addr-line>School of Public Health and Faculty of Health Science, University of the Witwatersrand, Johannesburg, South Africa</addr-line></aff><aff id="aff006"><label>6</label><addr-line>Division of Applied Research and Technology (DART), National Institute for Occupational Safety and Health (NIOSH), Centers for Disease Control and Prevention, Cincinnati, Ohio, United States of America</addr-line></aff><aff id="aff007"><label>7</label><addr-line>University of Illinois, Springfield, Illinois, United States of America</addr-line></aff><contrib-group><contrib contrib-type="editor"><name><surname>Cowling</surname><given-names>Benjamin J.</given-names></name><role>Academic Editor</role><xref ref-type="aff" rid="edit1"></xref></contrib></contrib-group><aff id="edit1"><addr-line>University of Hong Kong School of Public Health, HONG KONG</addr-line></aff><author-notes><fn fn-type="conflict" id="coi001"><p><bold>Competing Interests: </bold>The authors have declared that no competing interests exist.</p></fn><fn fn-type="con" id="contrib001"><p>Conceived and designed the experiments: ALC MW. Performed the experiments: ALC MM SW CC ST MA. Analyzed the data: ALC MM SW CC ST MA MW. Wrote the paper: ALC MM SW CC ST MA MW.</p></fn><corresp id="cor001">* E-mail: <email>DVJ1@cdc.gov</email></corresp></author-notes><pub-date pub-type="epub"><day>11</day><month>6</month><year>2015</year></pub-date><pub-date pub-type="collection"><year>2015</year></pub-date><volume>10</volume><issue>6</issue><elocation-id>e0128580</elocation-id><history><date date-type="received"><day>6</day><month>2</month><year>2015</year></date><date date-type="accepted"><day>28</day><month>4</month><year>2015</year></date></history><permissions><license xlink:href="https://creativecommons.org/publicdomain/zero/1.0/"><license-p>This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/publicdomain/zero/1.0/">Creative Commons CC0</ext-link> public domain dedication</license-p></license></permissions><self-uri content-type="pdf" xlink:type="simple" xlink:href="pone.0128580.pdf"></self-uri><abstract><p>Infectious diseases and underlying medical conditions common to Africa may affect influenza frequency and severity. We conducted a systematic review of published studies on influenza and the following co-infections or co-morbidities that are prevalent in Africa: dengue, malaria, measles, meningococcus, <italic>Pneumocystis jirovecii</italic> pneumonia (PCP), hemoglobinopathies, and malnutrition. Articles were identified except for influenza and PCP. Very few studies were from Africa. Sickle cell disease, dengue, and measles co-infection were found to increase the severity of influenza disease, though this is based on few studies of dengue and measles and the measles study was of low quality. The frequency of influenza was increased among patients with sickle cell disease. Influenza infection increased the frequency of meningococcal disease. Studies on malaria and malnutrition found mixed results. Age-adjusted morbidity and mortality from influenza may be more common in Africa because infections and diseases common in the region lead to more severe outcomes and increase the influenza burden. However, gaps exist in our knowledge about these interactions.</p></abstract><funding-group><funding-statement>This work is supported by the Centers for Disease Control and Prevention, Atlanta, Georgia, USA.</funding-statement></funding-group><counts><fig-count count="1"></fig-count><table-count count="3"></table-count><page-count count="17"></page-count></counts><custom-meta-group><custom-meta id="data-availability"><meta-name>Data Availability</meta-name><meta-value>As this is a systematic review of the pubished literature, all data is available in the published literature.</meta-value></custom-meta></custom-meta-group></article-meta><notes><title>Data Availability</title><p>As this is a systematic review of the pubished literature, all data is available in the published literature.</p></notes></front></pmc><affiliations><list><country><li>Afrique du Sud</li><li>États-Unis</li></country><region><li>Gauteng</li><li>Géorgie (États-Unis)</li><li>Illinois</li><li>Maryland</li><li>Ohio</li></region><settlement><li>Johannesbourg</li></settlement><orgName><li>Université du Witwatersrand</li></orgName></list><tree><country name="États-Unis"><region name="Géorgie (États-Unis)"><name sortKey="Cohen, Adam L" sort="Cohen, Adam L" uniqKey="Cohen A" first="Adam L." last="Cohen">Adam L. Cohen</name></region><name sortKey="Alexander Scott, Marissa" sort="Alexander Scott, Marissa" uniqKey="Alexander Scott M" first="Marissa" last="Alexander-Scott">Marissa Alexander-Scott</name><name sortKey="Alexander Scott, Marissa" sort="Alexander Scott, Marissa" uniqKey="Alexander Scott M" first="Marissa" last="Alexander-Scott">Marissa Alexander-Scott</name><name sortKey="Cohen, Adam L" sort="Cohen, Adam L" uniqKey="Cohen A" first="Adam L." last="Cohen">Adam L. Cohen</name><name sortKey="Mcmorrow, Meredith" sort="Mcmorrow, Meredith" uniqKey="Mcmorrow M" first="Meredith" last="Mcmorrow">Meredith Mcmorrow</name><name sortKey="Mcmorrow, Meredith" sort="Mcmorrow, Meredith" uniqKey="Mcmorrow M" first="Meredith" last="Mcmorrow">Meredith Mcmorrow</name><name sortKey="Tempia, Stefano" sort="Tempia, Stefano" uniqKey="Tempia S" first="Stefano" last="Tempia">Stefano Tempia</name><name sortKey="Widdowson, Marc Alain" sort="Widdowson, Marc Alain" uniqKey="Widdowson M" first="Marc-Alain" last="Widdowson">Marc-Alain Widdowson</name></country><country name="Afrique du Sud"><noRegion><name sortKey="Cohen, Adam L" sort="Cohen, Adam L" uniqKey="Cohen A" first="Adam L." last="Cohen">Adam L. Cohen</name></noRegion><name sortKey="Cohen, Cheryl" sort="Cohen, Cheryl" uniqKey="Cohen C" first="Cheryl" last="Cohen">Cheryl Cohen</name><name sortKey="Cohen, Cheryl" sort="Cohen, Cheryl" uniqKey="Cohen C" first="Cheryl" last="Cohen">Cheryl Cohen</name><name sortKey="Tempia, Stefano" sort="Tempia, Stefano" uniqKey="Tempia S" first="Stefano" last="Tempia">Stefano Tempia</name><name sortKey="Tempia, Stefano" sort="Tempia, Stefano" uniqKey="Tempia S" first="Stefano" last="Tempia">Stefano Tempia</name><name sortKey="Walaza, Sibongile" sort="Walaza, Sibongile" uniqKey="Walaza S" first="Sibongile" last="Walaza">Sibongile Walaza</name><name sortKey="Walaza, Sibongile" sort="Walaza, Sibongile" uniqKey="Walaza S" first="Sibongile" last="Walaza">Sibongile Walaza</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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