Effects of Maternal Worm Infections and Anthelminthic Treatment during Pregnancy on Infant Motor and Neurocognitive Functioning
Identifieur interne : 001A42 ( Ncbi/Merge ); précédent : 001A41; suivant : 001A43Effects of Maternal Worm Infections and Anthelminthic Treatment during Pregnancy on Infant Motor and Neurocognitive Functioning
Auteurs : Margaret Nampijja [Ouganda, Royaume-Uni] ; Barbara Apule [Ouganda] ; Swaib Lule [Ouganda] ; Hellen Akurut [Ouganda] ; Lawrence Muhangi [Ouganda] ; Emily L. Webb [Royaume-Uni] ; Charlie Lewis [Royaume-Uni] ; Alison M. Elliott [Ouganda, Royaume-Uni] ; Katie J. Alcock [Royaume-Uni]Source :
- Journal of the International Neuropsychological Society [ 1355-6177 ] ; 2012.
Abstract
We tested the hypothesis that maternal worm infections in pregnancy affect infant motor
and neurocognitive development, and that anthelminthic treatment during pregnancy can
reverse these effects. We used measures which examine infant motor, cognitive and
executive function, including inhibition. We assessed 983 Ugandan infants aged 15 months,
using locally appropriate measures within the Entebbe Mother and Baby Study, a trial of
anthelminthic treatment during pregnancy. Key exposures were maternal worm infections and
anthelminthic treatment during pregnancy. Effects of other health and social factors were
controlled for statistically. Of the five major worm species found in the pregnant women,
two had influences on the developmental measures: Maternal
Url:
DOI: 10.1017/S1355617712000768
PubMed: 23158229
PubMed Central: 3948080
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PMC:3948080Le document en format XML
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Pregnancy on Infant Motor and Neurocognitive Functioning</title><author><name sortKey="Nampijja, Margaret" sort="Nampijja, Margaret" uniqKey="Nampijja M" first="Margaret" last="Nampijja">Margaret Nampijja</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Apule, Barbara" sort="Apule, Barbara" uniqKey="Apule B" first="Barbara" last="Apule">Barbara Apule</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>Department of Obstetrics & Gynecology</addr-line>,<institution>Entebbe General Hospital</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lule, Swaib" sort="Lule, Swaib" uniqKey="Lule S" first="Swaib" last="Lule">Swaib Lule</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Akurut, Hellen" sort="Akurut, Hellen" uniqKey="Akurut H" first="Hellen" last="Akurut">Hellen Akurut</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muhangi, Lawrence" sort="Muhangi, Lawrence" uniqKey="Muhangi L" first="Lawrence" last="Muhangi">Lawrence Muhangi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Webb, Emily L" sort="Webb, Emily L" uniqKey="Webb E" first="Emily L." last="Webb">Emily L. Webb</name><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Department of Clinical Research</addr-line>,<institution>London School of Hygiene and Tropical Medicine</institution>,<addr-line>London</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lewis, Charlie" sort="Lewis, Charlie" uniqKey="Lewis C" first="Charlie" last="Lewis">Charlie Lewis</name><affiliation wicri:level="1"><nlm:aff id="aff2"><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Elliott, Alison M" sort="Elliott, Alison M" uniqKey="Elliott A" first="Alison M." last="Elliott">Alison M. Elliott</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Department of Clinical Research</addr-line>,<institution>London School of Hygiene and Tropical Medicine</institution>,<addr-line>London</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alcock, Katie J" sort="Alcock, Katie J" uniqKey="Alcock K" first="Katie J." last="Alcock">Katie J. Alcock</name><affiliation wicri:level="1"><nlm:aff id="aff2"><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23158229</idno><idno type="pmc">3948080</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948080</idno><idno type="RBID">PMC:3948080</idno><idno type="doi">10.1017/S1355617712000768</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002699</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002699</idno><idno type="wicri:Area/Pmc/Curation">002698</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002698</idno><idno type="wicri:Area/Pmc/Checkpoint">001E77</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001E77</idno><idno type="wicri:Area/Ncbi/Merge">001A42</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Effects of Maternal Worm Infections and Anthelminthic Treatment during
Pregnancy on Infant Motor and Neurocognitive Functioning</title><author><name sortKey="Nampijja, Margaret" sort="Nampijja, Margaret" uniqKey="Nampijja M" first="Margaret" last="Nampijja">Margaret Nampijja</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Apule, Barbara" sort="Apule, Barbara" uniqKey="Apule B" first="Barbara" last="Apule">Barbara Apule</name><affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>Department of Obstetrics & Gynecology</addr-line>,<institution>Entebbe General Hospital</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lule, Swaib" sort="Lule, Swaib" uniqKey="Lule S" first="Swaib" last="Lule">Swaib Lule</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Akurut, Hellen" sort="Akurut, Hellen" uniqKey="Akurut H" first="Hellen" last="Akurut">Hellen Akurut</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Muhangi, Lawrence" sort="Muhangi, Lawrence" uniqKey="Muhangi L" first="Lawrence" last="Muhangi">Lawrence Muhangi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Webb, Emily L" sort="Webb, Emily L" uniqKey="Webb E" first="Emily L." last="Webb">Emily L. Webb</name><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Department of Clinical Research</addr-line>,<institution>London School of Hygiene and Tropical Medicine</institution>,<addr-line>London</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lewis, Charlie" sort="Lewis, Charlie" uniqKey="Lewis C" first="Charlie" last="Lewis">Charlie Lewis</name><affiliation wicri:level="1"><nlm:aff id="aff2"><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Elliott, Alison M" sort="Elliott, Alison M" uniqKey="Elliott A" first="Alison M." last="Elliott">Alison M. Elliott</name><affiliation wicri:level="1"><nlm:aff id="aff1"><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></nlm:aff><country xml:lang="fr">Ouganda</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Department of Clinical Research</addr-line>,<institution>London School of Hygiene and Tropical Medicine</institution>,<addr-line>London</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alcock, Katie J" sort="Alcock, Katie J" uniqKey="Alcock K" first="Katie J." last="Alcock">Katie J. Alcock</name><affiliation wicri:level="1"><nlm:aff id="aff2"><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Journal of the International Neuropsychological Society</title><idno type="ISSN">1355-6177</idno><idno type="eISSN">1469-7661</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>We tested the hypothesis that maternal worm infections in pregnancy affect infant motor
and neurocognitive development, and that anthelminthic treatment during pregnancy can
reverse these effects. We used measures which examine infant motor, cognitive and
executive function, including inhibition. We assessed 983 Ugandan infants aged 15 months,
using locally appropriate measures within the Entebbe Mother and Baby Study, a trial of
anthelminthic treatment during pregnancy. Key exposures were maternal worm infections and
anthelminthic treatment during pregnancy. Effects of other health and social factors were
controlled for statistically. Of the five major worm species found in the pregnant women,
two had influences on the developmental measures: Maternal <italic>Mansonella
perstans</italic> and <italic>Strongyloides stercoralis</italic> infections showed
negative associations with the A-not B-task, and Language, respectively. Performance on
other psychomotor and cognitive measures was associated with illnesses during infancy and
infants’ behavior during assessment, but not with maternal worm infections. There were no
positive effects of maternal anthelminthic treatment on infant abilities.
<italic>Mansonella perstans</italic> and <italic>Strongyloides stercoralis</italic>infection during pregnancy seem associated with impaired early executive function and
language, respectively, but single-dose anthelminthic treatment during pregnancy was not
beneficial. The biological mechanisms that could underlie these neurocognitive effects are
discussed. (<italic>JINS</italic>, 2012, <italic>18</italic>, 1019–1030)</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Abubakar, A" uniqKey="Abubakar A">A. Abubakar</name></author><author><name sortKey="Holding, P" uniqKey="Holding P">P. Holding</name></author><author><name sortKey="Van Baar, A" uniqKey="Van Baar A">A. Van Baar</name></author><author><name sortKey="Newton, C R" uniqKey="Newton C">C.R. Newton</name></author><author><name sortKey="Van De Vijver, F J" uniqKey="Van De Vijver F">F.J. Van de Vijver</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abubakar, A" uniqKey="Abubakar A">A. Abubakar</name></author><author><name sortKey="Holding, P" uniqKey="Holding P">P. Holding</name></author><author><name sortKey="Van De Vijver, F" uniqKey="Van De Vijver F">F. Van de Vijver</name></author><author><name sortKey="Bomu, G" uniqKey="Bomu G">G. 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Int Neuropsychol Soc</journal-id><journal-id journal-id-type="iso-abbrev">J Int Neuropsychol Soc</journal-id><journal-id journal-id-type="publisher-id">INS</journal-id><journal-title-group><journal-title>Journal of the International Neuropsychological Society</journal-title></journal-title-group><issn pub-type="ppub">1355-6177</issn><issn pub-type="epub">1469-7661</issn><publisher><publisher-name>Cambridge University Press</publisher-name><publisher-loc>New York, USA</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">23158229</article-id><article-id pub-id-type="pmc">3948080</article-id><article-id pub-id-type="doi">10.1017/S1355617712000768</article-id><article-id pub-id-type="pii">S1355617712000768</article-id><article-id pub-id-type="publisher-id">00076</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Articles</subject></subj-group></article-categories><title-group><article-title>Effects of Maternal Worm Infections and Anthelminthic Treatment during
Pregnancy on Infant Motor and Neurocognitive Functioning</article-title><alt-title alt-title-type="left-running">M. Nampijja <italic>et al.</italic></alt-title><alt-title alt-title-type="right-running">Developmental effects of maternal
worms</alt-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Nampijja</surname><given-names>Margaret</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff2">2</xref><xref ref-type="corresp" rid="cor1"></xref></contrib><contrib contrib-type="author"><name><surname>Apule</surname><given-names>Barbara</given-names></name><xref ref-type="aff" rid="aff3">3</xref></contrib><contrib contrib-type="author"><name><surname>Lule</surname><given-names>Swaib</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Akurut</surname><given-names>Hellen</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Muhangi</surname><given-names>Lawrence</given-names></name><xref ref-type="aff" rid="aff1">1</xref></contrib><contrib contrib-type="author"><name><surname>Webb</surname><given-names>Emily L.</given-names></name><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Lewis</surname><given-names>Charlie</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib><contrib contrib-type="author"><name><surname>Elliott</surname><given-names>Alison M.</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff4">4</xref></contrib><contrib contrib-type="author"><name><surname>Alcock</surname><given-names>Katie J.</given-names></name><xref ref-type="aff" rid="aff2">2</xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Co-infections Studies Programme</addr-line>,<institution>MRC/UVRI Uganda Research Unit on AIDS</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></aff><aff id="aff2"><label>2</label><addr-line>Department of Psychology</addr-line>,<institution>Lancaster University</institution>,<addr-line>Lancaster</addr-line>,<country>United Kingdom</country></aff><aff id="aff3"><label>3</label><addr-line>Department of Obstetrics & Gynecology</addr-line>,<institution>Entebbe General Hospital</institution>,<addr-line>Entebbe</addr-line>,<country>Uganda</country></aff><aff id="aff4"><label>4</label><addr-line>Department of Clinical Research</addr-line>,<institution>London School of Hygiene and Tropical Medicine</institution>,<addr-line>London</addr-line>,<country>United Kingdom</country></aff><author-notes><corresp id="cor1">Correspondence and reprint requests to: Margaret Nampijja, Department of
Psychology, Lancaster University, Fylde College, Lancaster LA1 4YF, UK. E-mail: <email>m.nampijja@lancaster.ac.uk</email></corresp></author-notes><pub-date pub-type="ppub"><month>11</month><year>2012</year></pub-date><volume>18</volume><issue>6</issue><fpage>1019</fpage><lpage>1030</lpage><history><date date-type="received"><day>25</day><month>2</month><year>2011</year></date><date date-type="rev-recd"><day>05</day><month>5</month><year>2012</year></date><date date-type="accepted"><day>07</day><month>5</month><year>2012</year></date></history><permissions><copyright-statement>© The International Neuropsychological Society 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder>The International Neuropsychological Society</copyright-holder><license license-type="open-access"><license-p><pmc-comment>CREATIVE COMMONS</pmc-comment>The online version of this article is published within an Open Access
environment subject to the conditions of the Creative Commons
Attribution-NonCommercial-ShareAlike licence
<<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc-sa/3.0/">http://creativecommons.org/licenses/by-nc-sa/3.0/</ext-link>>. The written
permission of Cambridge University Press must be obtained for commercial
re-use.</license-p></license></permissions><self-uri xlink:title="pdf" xlink:type="simple" xlink:href="S1355617712000768a.pdf"></self-uri><abstract abstract-type="normal"><p>We tested the hypothesis that maternal worm infections in pregnancy affect infant motor
and neurocognitive development, and that anthelminthic treatment during pregnancy can
reverse these effects. We used measures which examine infant motor, cognitive and
executive function, including inhibition. We assessed 983 Ugandan infants aged 15 months,
using locally appropriate measures within the Entebbe Mother and Baby Study, a trial of
anthelminthic treatment during pregnancy. Key exposures were maternal worm infections and
anthelminthic treatment during pregnancy. Effects of other health and social factors were
controlled for statistically. Of the five major worm species found in the pregnant women,
two had influences on the developmental measures: Maternal <italic>Mansonella
perstans</italic> and <italic>Strongyloides stercoralis</italic> infections showed
negative associations with the A-not B-task, and Language, respectively. Performance on
other psychomotor and cognitive measures was associated with illnesses during infancy and
infants’ behavior during assessment, but not with maternal worm infections. There were no
positive effects of maternal anthelminthic treatment on infant abilities.
<italic>Mansonella perstans</italic> and <italic>Strongyloides stercoralis</italic>infection during pregnancy seem associated with impaired early executive function and
language, respectively, but single-dose anthelminthic treatment during pregnancy was not
beneficial. The biological mechanisms that could underlie these neurocognitive effects are
discussed. (<italic>JINS</italic>, 2012, <italic>18</italic>, 1019–1030)</p></abstract><kwd-group><title>Keywords</title><kwd>Pregnancy</kwd><kwd>Helminths</kwd><kwd>De-worming</kwd><kwd>Infancy</kwd><kwd>Psychomotor</kwd><kwd>Executive function</kwd></kwd-group><counts><fig-count count="0"></fig-count><table-count count="6"></table-count><page-count count="12"></page-count></counts></article-meta></front></pmc><affiliations><list><country><li>Ouganda</li><li>Royaume-Uni</li></country></list><tree><country name="Ouganda"><noRegion><name sortKey="Nampijja, Margaret" sort="Nampijja, Margaret" uniqKey="Nampijja M" first="Margaret" last="Nampijja">Margaret Nampijja</name></noRegion><name sortKey="Akurut, Hellen" sort="Akurut, Hellen" uniqKey="Akurut H" first="Hellen" last="Akurut">Hellen Akurut</name><name sortKey="Apule, Barbara" sort="Apule, Barbara" uniqKey="Apule B" first="Barbara" last="Apule">Barbara Apule</name><name sortKey="Elliott, Alison M" sort="Elliott, Alison M" uniqKey="Elliott A" first="Alison M." last="Elliott">Alison M. Elliott</name><name sortKey="Lule, Swaib" sort="Lule, Swaib" uniqKey="Lule S" first="Swaib" last="Lule">Swaib Lule</name><name sortKey="Muhangi, Lawrence" sort="Muhangi, Lawrence" uniqKey="Muhangi L" first="Lawrence" last="Muhangi">Lawrence Muhangi</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Nampijja, Margaret" sort="Nampijja, Margaret" uniqKey="Nampijja M" first="Margaret" last="Nampijja">Margaret Nampijja</name></noRegion><name sortKey="Alcock, Katie J" sort="Alcock, Katie J" uniqKey="Alcock K" first="Katie J." last="Alcock">Katie J. Alcock</name><name sortKey="Elliott, Alison M" sort="Elliott, Alison M" uniqKey="Elliott A" first="Alison M." last="Elliott">Alison M. Elliott</name><name sortKey="Lewis, Charlie" sort="Lewis, Charlie" uniqKey="Lewis C" first="Charlie" last="Lewis">Charlie Lewis</name><name sortKey="Webb, Emily L" sort="Webb, Emily L" uniqKey="Webb E" first="Emily L." last="Webb">Emily L. Webb</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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