A Situational Analysis of Antimicrobial Drug Resistance in Africa: Are We Losing the Battle?
Identifieur interne : 001880 ( Ncbi/Merge ); précédent : 001879; suivant : 001881A Situational Analysis of Antimicrobial Drug Resistance in Africa: Are We Losing the Battle?
Auteurs : Andrew Nyerere Kimang'ASource :
- Ethiopian Journal of Health Sciences [ 1029-1857 ] ; 2012.
Abstract
The first arrival of a sizable shipment of penicillin at the North African Theatre of Operations for USA military use in 1943 was a landmark that turned a new chapter of antibiotic use in Africa. Over the past decade the expansion of resources and the technological advances have meant that much larger quantities of drugs are available in developing countries than ever before. As a result, many more individuals are receiving necessary treatment or therapy than just ten years ago. This very welcome event is accompanied by the terrible irony that increases in drug availability and use can promote drug resistance and render the same life-saving drugs ineffective.
The study focused on bacterial pathogens. One hundred and three relevant literatures were identified from the PubMed online database. The coverage included research articles concerning antimicrobial resistance involving subjects of an African country.
Resistant bacteria are on a war path and evidently have acquired an edge over us. Our actions are evidently fuelling the resistance. The indiscriminate use of antibiotics in humans and livestock, wrong and substandard prescriptions by unqualified ‘medical personnel’ together with poor diagnosis or lack of it are all adding fuel to the already fired train of resistant microbes.
To win the war and turn tables as we did with the discovery of penicillin and other antimicrobials in the 1940s, then we must all act now. Antimicrobial stewardship programs-Education, training of laboratory personnel and investment in laboratory infrastructure development are desirable in these situations
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PubMed: 22876078
PubMed Central: 3407837
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Situational Analysis of Antimicrobial Drug Resistance in Africa: Are We Losing the Battle?</title><author><name sortKey="Kimang A, Andrew Nyerere" sort="Kimang A, Andrew Nyerere" uniqKey="Kimang A A" first="Andrew Nyerere" last="Kimang'A">Andrew Nyerere Kimang'A</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22876078</idno><idno type="pmc">3407837</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407837</idno><idno type="RBID">PMC:3407837</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">002E22</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002E22</idno><idno type="wicri:Area/Pmc/Curation">002E21</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002E21</idno><idno type="wicri:Area/Pmc/Checkpoint">001F86</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001F86</idno><idno type="wicri:Area/Ncbi/Merge">001880</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">A Situational Analysis of Antimicrobial Drug Resistance in Africa: Are We Losing the Battle?</title><author><name sortKey="Kimang A, Andrew Nyerere" sort="Kimang A, Andrew Nyerere" uniqKey="Kimang A A" first="Andrew Nyerere" last="Kimang'A">Andrew Nyerere Kimang'A</name></author></analytic><series><title level="j">Ethiopian Journal of Health Sciences</title><idno type="ISSN">1029-1857</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The first arrival of a sizable shipment of penicillin at the North African Theatre of Operations for USA military use in 1943 was a landmark that turned a new chapter of antibiotic use in Africa. Over the past decade the expansion of resources and the technological advances have meant that much larger quantities of drugs are available in developing countries than ever before. As a result, many more individuals are receiving necessary treatment or therapy than just ten years ago. This very welcome event is accompanied by the terrible irony that increases in drug availability and use can promote drug resistance and render the same life-saving drugs ineffective.</p></sec><sec sec-type="methods"><title>Methods</title><p>The study focused on bacterial pathogens. One hundred and three relevant literatures were identified from the PubMed online database. The coverage included research articles concerning antimicrobial resistance involving subjects of an African country.</p></sec><sec sec-type="results"><title>Results</title><p>Resistant bacteria are on a war path and evidently have acquired an edge over us. Our actions are evidently fuelling the resistance. The indiscriminate use of antibiotics in humans and livestock, wrong and substandard prescriptions by unqualified ‘medical personnel’ together with poor diagnosis or lack of it are all adding fuel to the already fired train of resistant microbes.</p></sec><sec sec-type="conclusion"><title>Conclusion</title><p>To win the war and turn tables as we did with the discovery of penicillin and other antimicrobials in the 1940s, then we must all act now. Antimicrobial stewardship programs-Education, training of laboratory personnel and investment in laboratory infrastructure development are desirable in these situations</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Fleming, A" uniqKey="Fleming A">A Fleming</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Florey, Hw" uniqKey="Florey H">HW Florey</name></author><author><name sortKey="Abraham, Ep" uniqKey="Abraham E">EP Abraham</name></author><author><name sortKey="Gardner, Ad" uniqKey="Gardner A">AD Gardner</name></author><author><name sortKey="Chain, E" uniqKey="Chain E">E Chain</name></author><author><name sortKey="Fletcher, Cm" uniqKey="Fletcher C">CM Fletcher</name></author><author><name sortKey="Heatley, Ng" uniqKey="Heatley N">NG Heatley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fulton, Jf" uniqKey="Fulton J">JF 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Ethiop J Health Sci</journal-id><journal-id journal-id-type="iso-abbrev">Ethiop J Health Sci</journal-id><journal-title-group><journal-title>Ethiopian Journal of Health Sciences</journal-title></journal-title-group><issn pub-type="ppub">1029-1857</issn><publisher><publisher-name>Research and Publications Office of Jimma University</publisher-name><publisher-loc>Jimma, Ethiopia</publisher-loc></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">22876078</article-id><article-id pub-id-type="pmc">3407837</article-id><article-id pub-id-type="publisher-id">jEJHS.v22.i2.pg135</article-id><article-categories><subj-group subj-group-type="heading"><subject>Review Article</subject></subj-group></article-categories><title-group><article-title>A Situational Analysis of Antimicrobial Drug Resistance in Africa: Are We Losing the Battle?</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Kimang'a</surname><given-names>Andrew Nyerere</given-names></name></contrib></contrib-group><aff>Sub-department of Medical Microbiology, Faculty of Science, Jomo Kenyatta University of Agriculture and Technology. P.O. Box 62000-00100, Nairobi-Kenya. Email:<email>kinyerere@yahoo.com</email></aff><pub-date pub-type="ppub"><month>7</month><year>2012</year></pub-date><volume>22</volume><issue>2</issue><fpage>135</fpage><lpage>143</lpage><permissions><copyright-statement>Copyright © Jimma University, Research & Publications Office 2012</copyright-statement><copyright-year>2012</copyright-year></permissions><abstract abstract-type="executive-summary"><sec><title>Background</title><p>The first arrival of a sizable shipment of penicillin at the North African Theatre of Operations for USA military use in 1943 was a landmark that turned a new chapter of antibiotic use in Africa. Over the past decade the expansion of resources and the technological advances have meant that much larger quantities of drugs are available in developing countries than ever before. As a result, many more individuals are receiving necessary treatment or therapy than just ten years ago. This very welcome event is accompanied by the terrible irony that increases in drug availability and use can promote drug resistance and render the same life-saving drugs ineffective.</p></sec><sec sec-type="methods"><title>Methods</title><p>The study focused on bacterial pathogens. One hundred and three relevant literatures were identified from the PubMed online database. The coverage included research articles concerning antimicrobial resistance involving subjects of an African country.</p></sec><sec sec-type="results"><title>Results</title><p>Resistant bacteria are on a war path and evidently have acquired an edge over us. Our actions are evidently fuelling the resistance. The indiscriminate use of antibiotics in humans and livestock, wrong and substandard prescriptions by unqualified ‘medical personnel’ together with poor diagnosis or lack of it are all adding fuel to the already fired train of resistant microbes.</p></sec><sec sec-type="conclusion"><title>Conclusion</title><p>To win the war and turn tables as we did with the discovery of penicillin and other antimicrobials in the 1940s, then we must all act now. Antimicrobial stewardship programs-Education, training of laboratory personnel and investment in laboratory infrastructure development are desirable in these situations</p></sec></abstract><kwd-group><kwd>Antibiotics</kwd><kwd>Resistance</kwd><kwd>Bacteria</kwd></kwd-group></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Kimang A, Andrew Nyerere" sort="Kimang A, Andrew Nyerere" uniqKey="Kimang A A" first="Andrew Nyerere" last="Kimang'A">Andrew Nyerere Kimang'A</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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