HIV Wasting Syndrome in a Nigerian Failing Antiretroviral Therapy: A Case Report and Review of the Literature
Identifieur interne : 001111 ( Ncbi/Merge ); précédent : 001110; suivant : 001112HIV Wasting Syndrome in a Nigerian Failing Antiretroviral Therapy: A Case Report and Review of the Literature
Auteurs : Dimie Ogoina [Nigeria] ; Reginald O. Obiako [Nigeria] ; Haruna M. Muktar [Nigeria]Source :
- Case Reports in Medicine [ 1687-9627 ] ; 2010.
Abstract
The HIV wasting syndrome represented the face of HIV/AIDS before the advent of highly active antiretroviral therapy (HAART). Although the incidence of wasting has declined since the introduction of HAART, weight loss remains common in patients receiving HAART, especially in the setting of a failing HAART regimen. As we are not aware of any previous reports from Nigeria, we report a case of the classical wasting syndrome in a Nigerian female who had both virological and immunological HAART failure due to poor adherence. The influence of a failing HAART regimen, socioeconomic status, and other clinical variables in the wasting syndrome are discussed.
Url:
DOI: 10.1155/2010/192060
PubMed: 21209738
PubMed Central: 3014846
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Muktar</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Haematology, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Haematology, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria</wicri:regionArea><wicri:noRegion>Zaria</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21209738</idno><idno type="pmc">3014846</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014846</idno><idno type="RBID">PMC:3014846</idno><idno type="doi">10.1155/2010/192060</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">000E10</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000E10</idno><idno type="wicri:Area/Pmc/Curation">000E09</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000E09</idno><idno type="wicri:Area/Pmc/Checkpoint">002555</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002555</idno><idno type="wicri:Area/Ncbi/Merge">001111</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">HIV Wasting Syndrome in a Nigerian Failing Antiretroviral Therapy: A Case Report and Review of the Literature</title><author><name sortKey="Ogoina, Dimie" sort="Ogoina, Dimie" uniqKey="Ogoina D" first="Dimie" last="Ogoina">Dimie Ogoina</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria</wicri:regionArea><wicri:noRegion>Zaria</wicri:noRegion></affiliation></author><author><name sortKey="Obiako, Reginald O" sort="Obiako, Reginald O" uniqKey="Obiako R" first="Reginald O." last="Obiako">Reginald O. Obiako</name><affiliation wicri:level="1"><nlm:aff id="I1">Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria</wicri:regionArea><wicri:noRegion>Zaria</wicri:noRegion></affiliation></author><author><name sortKey="Muktar, Haruna M" sort="Muktar, Haruna M" uniqKey="Muktar H" first="Haruna M." last="Muktar">Haruna M. Muktar</name><affiliation wicri:level="1"><nlm:aff id="I2">Department of Haematology, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Department of Haematology, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria</wicri:regionArea><wicri:noRegion>Zaria</wicri:noRegion></affiliation></author></analytic><series><title level="j">Case Reports in Medicine</title><idno type="ISSN">1687-9627</idno><idno type="eISSN">1687-9635</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The HIV wasting syndrome represented the face of HIV/AIDS before the advent of highly active antiretroviral therapy (HAART). Although the incidence of wasting has declined since the introduction of HAART, weight loss remains common in patients receiving HAART, especially in the setting of a failing HAART regimen. As we are not aware of any previous reports from Nigeria, we report a case of the classical wasting syndrome in a Nigerian female who had both virological and immunological HAART failure due to poor adherence. The influence of a failing HAART regimen, socioeconomic status, and other clinical variables in the wasting syndrome are discussed.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Smit, E" uniqKey="Smit E">E Smit</name></author><author><name sortKey="Skolasky, Rl" uniqKey="Skolasky R">RL Skolasky</name></author><author><name sortKey="Dobs, As" uniqKey="Dobs A">AS Dobs</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Wanke, Ca" uniqKey="Wanke C">CA Wanke</name></author><author><name sortKey="Silva, M" uniqKey="Silva M">M Silva</name></author><author><name sortKey="Knox, Ta" uniqKey="Knox T">TA Knox</name></author><author><name sortKey="Forrester, J" uniqKey="Forrester J">J Forrester</name></author><author><name sortKey="Speigelman, D" uniqKey="Speigelman D">D Speigelman</name></author><author><name sortKey="Gorbach, Sl" uniqKey="Gorbach S">SL 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<front><journal-meta><journal-id journal-id-type="nlm-ta">Case Rep Med</journal-id><journal-id journal-id-type="iso-abbrev">Case Rep Med</journal-id><journal-id journal-id-type="publisher-id">CRIM</journal-id><journal-title-group><journal-title>Case Reports in Medicine</journal-title></journal-title-group><issn pub-type="ppub">1687-9627</issn><issn pub-type="epub">1687-9635</issn><publisher><publisher-name>Hindawi Publishing Corporation</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">21209738</article-id><article-id pub-id-type="pmc">3014846</article-id><article-id pub-id-type="doi">10.1155/2010/192060</article-id><article-categories><subj-group subj-group-type="heading"><subject>Case Report</subject></subj-group></article-categories><title-group><article-title>HIV Wasting Syndrome in a Nigerian Failing Antiretroviral Therapy: A Case Report and Review of the Literature</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Ogoina</surname><given-names>Dimie</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Obiako</surname><given-names>Reginald O.</given-names></name><xref ref-type="aff" rid="I1"><sup>1</sup></xref></contrib><contrib contrib-type="author"><name><surname>Muktar</surname><given-names>Haruna M.</given-names></name><xref ref-type="aff" rid="I2"><sup>2</sup></xref></contrib></contrib-group><aff id="I1"><sup>1</sup>Department of Medicine, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria</aff><aff id="I2"><sup>2</sup>Department of Haematology, Ahmadu Bello University Teaching Hospital (ABUTH), Zaria, Nigeria</aff><author-notes><corresp id="cor1">*Dimie Ogoina: <email>dimostic@yahoo.co.uk</email></corresp><fn fn-type="other"><p>Academic Editor: A. R. Satoskar</p></fn></author-notes><pub-date pub-type="ppub"><year>2010</year></pub-date><pub-date pub-type="epub"><day>27</day><month>12</month><year>2010</year></pub-date><volume>2010</volume><elocation-id>192060</elocation-id><history><date date-type="received"><day>15</day><month>9</month><year>2010</year></date><date date-type="accepted"><day>3</day><month>12</month><year>2010</year></date></history><permissions><copyright-statement>Copyright © 2010 Dimie Ogoina et al.</copyright-statement><copyright-year>2010</copyright-year><license xlink:href="https://creativecommons.org/licenses/by/3.0/"><license-p>This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</license-p></license></permissions><abstract><p>The HIV wasting syndrome represented the face of HIV/AIDS before the advent of highly active antiretroviral therapy (HAART). Although the incidence of wasting has declined since the introduction of HAART, weight loss remains common in patients receiving HAART, especially in the setting of a failing HAART regimen. As we are not aware of any previous reports from Nigeria, we report a case of the classical wasting syndrome in a Nigerian female who had both virological and immunological HAART failure due to poor adherence. The influence of a failing HAART regimen, socioeconomic status, and other clinical variables in the wasting syndrome are discussed.</p></abstract></article-meta></front><floats-group><fig id="fig1" position="float"><label>Figure 1</label><graphic xlink:href="CRIM2010-192060.001"></graphic></fig><fig id="fig2" position="float"><label>Figure 2</label><graphic xlink:href="CRIM2010-192060.002"></graphic></fig></floats-group></pmc><affiliations><list><country><li>Nigeria</li></country></list><tree><country name="Nigeria"><noRegion><name sortKey="Ogoina, Dimie" sort="Ogoina, Dimie" uniqKey="Ogoina D" first="Dimie" last="Ogoina">Dimie Ogoina</name></noRegion><name sortKey="Muktar, Haruna M" sort="Muktar, Haruna M" uniqKey="Muktar H" first="Haruna M." last="Muktar">Haruna M. Muktar</name><name sortKey="Obiako, Reginald O" sort="Obiako, Reginald O" uniqKey="Obiako R" first="Reginald O." last="Obiako">Reginald O. Obiako</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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