Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics
Identifieur interne : 000E66 ( Ncbi/Merge ); précédent : 000E65; suivant : 000E67Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics
Auteurs : Kartik K. Venkatesh [États-Unis] ; Guy De Bruyn [Afrique du Sud] ; Mark N. Lurie [États-Unis] ; Lerato Mohapi [Afrique du Sud] ; Paul Pronyk [États-Unis] ; Mosa Moshabela [Afrique du Sud] ; Edmore Marinda [Afrique du Sud] ; Glenda E. Gray [Afrique du Sud] ; Elizabeth W. Triche [États-Unis] ; Neil A. Martinson [Afrique du Sud, États-Unis]Source :
- AIDS (London, England) [ 0269-9370 ] ; 2010.
Descripteurs français
- KwdFr :
- Acceptation des soins par le patient (), Acceptation des soins par le patient (psychologie), Adulte, Charge virale, Comportement sexuel (psychologie), Connaissances, attitudes et pratiques en santé, Femelle, Humains, Infections à VIH (psychologie), Infections à VIH (traitement médicamenteux), Infections à VIH (épidémiologie), Mâle, Numération des lymphocytes CD4, Prise de risque, République d'Afrique du Sud (épidémiologie), Soins de santé primaires (), Thérapie antirétrovirale hautement active, Études longitudinales, Études prospectives.
- MESH :
- psychologie : Acceptation des soins par le patient, Comportement sexuel, Infections à VIH.
- traitement médicamenteux : Infections à VIH.
- épidémiologie : Infections à VIH, République d'Afrique du Sud.
- Acceptation des soins par le patient, Adulte, Charge virale, Connaissances, attitudes et pratiques en santé, Femelle, Humains, Mâle, Numération des lymphocytes CD4, Prise de risque, Soins de santé primaires, Thérapie antirétrovirale hautement active, Études longitudinales, Études prospectives.
- Wicri :
- geographic : Afrique du Sud.
English descriptors
- KwdEn :
- Adult, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Female, HIV Infections (drug therapy), HIV Infections (epidemiology), HIV Infections (psychology), Health Knowledge, Attitudes, Practice, Humans, Longitudinal Studies, Male, Patient Acceptance of Health Care (psychology), Patient Acceptance of Health Care (statistics & numerical data), Primary Health Care (statistics & numerical data), Prospective Studies, Risk-Taking, Sexual Behavior (psychology), South Africa (epidemiology), Viral Load.
- MESH :
- geographic , epidemiology : South Africa.
- drug therapy : HIV Infections.
- epidemiology : HIV Infections.
- psychology : HIV Infections, Patient Acceptance of Health Care, Sexual Behavior.
- statistics & numerical data : Patient Acceptance of Health Care, Primary Health Care.
- Adult, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Female, Health Knowledge, Attitudes, Practice, Humans, Longitudinal Studies, Male, Prospective Studies, Risk-Taking, Viral Load.
Abstract
In light of increasing access to highly active antiretroviral treatment (HAART) in sub-Saharan Africa, we conducted a longitudinal study to assess the impact of HAART on sexual risk behaviors among HIV-infected South Africans in urban and rural primary care clinics.
Prospective observational cohort study.
We conducted a cohort study at rural and urban primary care HIV clinics in South Africa consisting of 1544 men and 4719 women enrolled from 2003–2010, representing 19703 clinic visits. The primary outcomes were being sexually active, unprotected sex, and >1 sex partner and were evaluated at six monthly intervals. Generalized estimated equations assessed the impact of HAART on sexual risk behaviors.
Among 6263 HIV-infected men and women, over a third (37.2%) initiated HAART during study follow-up. In comparison to pre-HAART follow-up, visits while receiving HAART were associated with a decrease in those reporting being sexually active (AOR: 0.86 [95% CI: 0.78–0.95]). Unprotected sex and having >1 sex partner were reduced at visits following HAART initiation compared to pre-HAART visits (AOR: 0.40 [95% CI: 0.34–0.46] and AOR: 0.20 [95% CI: 0.14–0.29], respectively).
Sexual risk behavior significantly decreased following HAART initiation among HIV-infected South African men and women in primary care programs. The further expansion of antiretroviral treatment programs could enhance HIV prevention efforts in Africa.
Url:
DOI: 10.1097/QAD.0b013e32833e78d4
PubMed: 20808202
PubMed Central: 3130627
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Venkatesh</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="De Bruyn, Guy" sort="De Bruyn, Guy" uniqKey="De Bruyn G" first="Guy" last="De Bruyn">Guy De Bruyn</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Lurie, Mark N" sort="Lurie, Mark N" uniqKey="Lurie M" first="Mark N" last="Lurie">Mark N. Lurie</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Mohapi, Lerato" sort="Mohapi, Lerato" uniqKey="Mohapi L" first="Lerato" last="Mohapi">Lerato Mohapi</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Pronyk, Paul" sort="Pronyk, Paul" uniqKey="Pronyk P" first="Paul" last="Pronyk">Paul Pronyk</name><affiliation wicri:level="4"><nlm:aff id="A3"> Millennium Villages Project, The Earth Institute, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Millennium Villages Project, The Earth Institute, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Moshabela, Mosa" sort="Moshabela, Mosa" uniqKey="Moshabela M" first="Mosa" last="Moshabela">Mosa Moshabela</name><affiliation wicri:level="4"><nlm:aff id="A4"> School of Public Health, University of the Witwatersrand, Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> School of Public Health, University of the Witwatersrand, Johannesburg</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Marinda, Edmore" sort="Marinda, Edmore" uniqKey="Marinda E" first="Edmore" last="Marinda">Edmore Marinda</name><affiliation wicri:level="4"><nlm:aff id="A4"> School of Public Health, University of the Witwatersrand, Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> School of Public Health, University of the Witwatersrand, Johannesburg</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Gray, Glenda E" sort="Gray, Glenda E" uniqKey="Gray G" first="Glenda E" last="Gray">Glenda E. Gray</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Triche, Elizabeth W" sort="Triche, Elizabeth W" uniqKey="Triche E" first="Elizabeth W" last="Triche">Elizabeth W. Triche</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Martinson, Neil A" sort="Martinson, Neil A" uniqKey="Martinson N" first="Neil A" last="Martinson">Neil A. Martinson</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Johns Hopkins School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Johns Hopkins School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">AIDS (London, England)</title><idno type="ISSN">0269-9370</idno><idno type="eISSN">1473-5571</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Antiretroviral Therapy, Highly Active</term><term>CD4 Lymphocyte Count</term><term>Female</term><term>HIV Infections (drug therapy)</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (psychology)</term><term>Health Knowledge, Attitudes, Practice</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Patient Acceptance of Health Care (psychology)</term><term>Patient Acceptance of Health Care (statistics & numerical data)</term><term>Primary Health Care (statistics & numerical data)</term><term>Prospective Studies</term><term>Risk-Taking</term><term>Sexual Behavior (psychology)</term><term>South Africa (epidemiology)</term><term>Viral Load</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acceptation des soins par le patient ()</term><term>Acceptation des soins par le patient (psychologie)</term><term>Adulte</term><term>Charge virale</term><term>Comportement sexuel (psychologie)</term><term>Connaissances, attitudes et pratiques en santé</term><term>Femelle</term><term>Humains</term><term>Infections à VIH (psychologie)</term><term>Infections à VIH (traitement médicamenteux)</term><term>Infections à VIH (épidémiologie)</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prise de risque</term><term>République d'Afrique du Sud (épidémiologie)</term><term>Soins de santé primaires ()</term><term>Thérapie antirétrovirale hautement active</term><term>Études longitudinales</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>South Africa</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Acceptation des soins par le patient</term><term>Comportement sexuel</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>HIV Infections</term><term>Patient Acceptance of Health Care</term><term>Sexual Behavior</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Patient Acceptance of Health Care</term><term>Primary Health Care</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term><term>République d'Afrique du Sud</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Antiretroviral Therapy, Highly Active</term><term>CD4 Lymphocyte Count</term><term>Female</term><term>Health Knowledge, Attitudes, Practice</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Prospective Studies</term><term>Risk-Taking</term><term>Viral Load</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Acceptation des soins par le patient</term><term>Adulte</term><term>Charge virale</term><term>Connaissances, attitudes et pratiques en santé</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prise de risque</term><term>Soins de santé primaires</term><term>Thérapie antirétrovirale hautement active</term><term>Études longitudinales</term><term>Études prospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Afrique du Sud</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">In light of increasing access to highly active antiretroviral treatment (HAART) in sub-Saharan Africa, we conducted a longitudinal study to assess the impact of HAART on sexual risk behaviors among HIV-infected South Africans in urban and rural primary care clinics.</p></sec><sec id="S2"><title>Design</title><p id="P2">Prospective observational cohort study.</p></sec><sec sec-type="methods" id="S3"><title>Methods</title><p id="P3">We conducted a cohort study at rural and urban primary care HIV clinics in South Africa consisting of 1544 men and 4719 women enrolled from 2003–2010, representing 19703 clinic visits. The primary outcomes were being sexually active, unprotected sex, and >1 sex partner and were evaluated at six monthly intervals. Generalized estimated equations assessed the impact of HAART on sexual risk behaviors.</p></sec><sec id="S4"><title>Results</title><p id="P4">Among 6263 HIV-infected men and women, over a third (37.2%) initiated HAART during study follow-up. In comparison to pre-HAART follow-up, visits while receiving HAART were associated with a decrease in those reporting being sexually active (AOR: 0.86 [95% CI: 0.78–0.95]). Unprotected sex and having >1 sex partner were reduced at visits following HAART initiation compared to pre-HAART visits (AOR: 0.40 [95% CI: 0.34–0.46] and AOR: 0.20 [95% CI: 0.14–0.29], respectively).</p></sec><sec id="S5"><title>Conclusions</title><p id="P5">Sexual risk behavior significantly decreased following HAART initiation among HIV-infected South African men and women in primary care programs. The further expansion of antiretroviral treatment programs could enhance HIV prevention efforts in Africa.</p></sec></div></front></TEI><double pmid="20808202"><pmc><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics</title><author><name sortKey="Venkatesh, Kartik K" sort="Venkatesh, Kartik K" uniqKey="Venkatesh K" first="Kartik K" last="Venkatesh">Kartik K. Venkatesh</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="De Bruyn, Guy" sort="De Bruyn, Guy" uniqKey="De Bruyn G" first="Guy" last="De Bruyn">Guy De Bruyn</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Lurie, Mark N" sort="Lurie, Mark N" uniqKey="Lurie M" first="Mark N" last="Lurie">Mark N. Lurie</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Mohapi, Lerato" sort="Mohapi, Lerato" uniqKey="Mohapi L" first="Lerato" last="Mohapi">Lerato Mohapi</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Pronyk, Paul" sort="Pronyk, Paul" uniqKey="Pronyk P" first="Paul" last="Pronyk">Paul Pronyk</name><affiliation wicri:level="4"><nlm:aff id="A3"> Millennium Villages Project, The Earth Institute, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Millennium Villages Project, The Earth Institute, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Moshabela, Mosa" sort="Moshabela, Mosa" uniqKey="Moshabela M" first="Mosa" last="Moshabela">Mosa Moshabela</name><affiliation wicri:level="4"><nlm:aff id="A4"> School of Public Health, University of the Witwatersrand, Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> School of Public Health, University of the Witwatersrand, Johannesburg</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Marinda, Edmore" sort="Marinda, Edmore" uniqKey="Marinda E" first="Edmore" last="Marinda">Edmore Marinda</name><affiliation wicri:level="4"><nlm:aff id="A4"> School of Public Health, University of the Witwatersrand, Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> School of Public Health, University of the Witwatersrand, Johannesburg</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Gray, Glenda E" sort="Gray, Glenda E" uniqKey="Gray G" first="Glenda E" last="Gray">Glenda E. Gray</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Triche, Elizabeth W" sort="Triche, Elizabeth W" uniqKey="Triche E" first="Elizabeth W" last="Triche">Elizabeth W. Triche</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Martinson, Neil A" sort="Martinson, Neil A" uniqKey="Martinson N" first="Neil A" last="Martinson">Neil A. Martinson</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Johns Hopkins School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Johns Hopkins School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">20808202</idno><idno type="pmc">3130627</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130627</idno><idno type="RBID">PMC:3130627</idno><idno type="doi">10.1097/QAD.0b013e32833e78d4</idno><date when="2010">2010</date><idno type="wicri:Area/Pmc/Corpus">001200</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001200</idno><idno type="wicri:Area/Pmc/Curation">001199</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001199</idno><idno type="wicri:Area/Pmc/Checkpoint">002605</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002605</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics</title><author><name sortKey="Venkatesh, Kartik K" sort="Venkatesh, Kartik K" uniqKey="Venkatesh K" first="Kartik K" last="Venkatesh">Kartik K. Venkatesh</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="De Bruyn, Guy" sort="De Bruyn, Guy" uniqKey="De Bruyn G" first="Guy" last="De Bruyn">Guy De Bruyn</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Lurie, Mark N" sort="Lurie, Mark N" uniqKey="Lurie M" first="Mark N" last="Lurie">Mark N. Lurie</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Mohapi, Lerato" sort="Mohapi, Lerato" uniqKey="Mohapi L" first="Lerato" last="Mohapi">Lerato Mohapi</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Pronyk, Paul" sort="Pronyk, Paul" uniqKey="Pronyk P" first="Paul" last="Pronyk">Paul Pronyk</name><affiliation wicri:level="4"><nlm:aff id="A3"> Millennium Villages Project, The Earth Institute, Columbia University, New York, NY, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Millennium Villages Project, The Earth Institute, Columbia University, New York, NY</wicri:regionArea><placeName><region type="state">État de New York</region><settlement type="city">New York</settlement></placeName><orgName type="university">Université Columbia</orgName></affiliation></author><author><name sortKey="Moshabela, Mosa" sort="Moshabela, Mosa" uniqKey="Moshabela M" first="Mosa" last="Moshabela">Mosa Moshabela</name><affiliation wicri:level="4"><nlm:aff id="A4"> School of Public Health, University of the Witwatersrand, Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> School of Public Health, University of the Witwatersrand, Johannesburg</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Marinda, Edmore" sort="Marinda, Edmore" uniqKey="Marinda E" first="Edmore" last="Marinda">Edmore Marinda</name><affiliation wicri:level="4"><nlm:aff id="A4"> School of Public Health, University of the Witwatersrand, Johannesburg, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> School of Public Health, University of the Witwatersrand, Johannesburg</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Gray, Glenda E" sort="Gray, Glenda E" uniqKey="Gray G" first="Glenda E" last="Gray">Glenda E. Gray</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Triche, Elizabeth W" sort="Triche, Elizabeth W" uniqKey="Triche E" first="Elizabeth W" last="Triche">Elizabeth W. Triche</name><affiliation wicri:level="4"><nlm:aff id="A1"> Department of Community Health, Alpert Medical School, Brown University, Providence, RI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Department of Community Health, Alpert Medical School, Brown University, Providence, RI</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="Martinson, Neil A" sort="Martinson, Neil A" uniqKey="Martinson N" first="Neil A" last="Martinson">Neil A. Martinson</name><affiliation wicri:level="4"><nlm:aff id="A2"> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea> Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation><affiliation wicri:level="2"><nlm:aff id="A5"> Johns Hopkins School of Medicine, Baltimore, MD, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea> Johns Hopkins School of Medicine, Baltimore, MD</wicri:regionArea><placeName><region type="state">Maryland</region></placeName></affiliation></author></analytic><series><title level="j">AIDS (London, England)</title><idno type="ISSN">0269-9370</idno><idno type="eISSN">1473-5571</idno><imprint><date when="2010">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec id="S1"><title>Objective</title><p id="P1">In light of increasing access to highly active antiretroviral treatment (HAART) in sub-Saharan Africa, we conducted a longitudinal study to assess the impact of HAART on sexual risk behaviors among HIV-infected South Africans in urban and rural primary care clinics.</p></sec><sec id="S2"><title>Design</title><p id="P2">Prospective observational cohort study.</p></sec><sec sec-type="methods" id="S3"><title>Methods</title><p id="P3">We conducted a cohort study at rural and urban primary care HIV clinics in South Africa consisting of 1544 men and 4719 women enrolled from 2003–2010, representing 19703 clinic visits. The primary outcomes were being sexually active, unprotected sex, and >1 sex partner and were evaluated at six monthly intervals. Generalized estimated equations assessed the impact of HAART on sexual risk behaviors.</p></sec><sec id="S4"><title>Results</title><p id="P4">Among 6263 HIV-infected men and women, over a third (37.2%) initiated HAART during study follow-up. In comparison to pre-HAART follow-up, visits while receiving HAART were associated with a decrease in those reporting being sexually active (AOR: 0.86 [95% CI: 0.78–0.95]). Unprotected sex and having >1 sex partner were reduced at visits following HAART initiation compared to pre-HAART visits (AOR: 0.40 [95% CI: 0.34–0.46] and AOR: 0.20 [95% CI: 0.14–0.29], respectively).</p></sec><sec id="S5"><title>Conclusions</title><p id="P5">Sexual risk behavior significantly decreased following HAART initiation among HIV-infected South African men and women in primary care programs. The further expansion of antiretroviral treatment programs could enhance HIV prevention efforts in Africa.</p></sec></div></front></TEI></pmc><pubmed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics.</title><author><name sortKey="Venkatesh, Kartik K" sort="Venkatesh, Kartik K" uniqKey="Venkatesh K" first="Kartik K" last="Venkatesh">Kartik K. Venkatesh</name><affiliation wicri:level="4"><nlm:affiliation>Department of Community Health, Brown University, Providence, Rhode Island, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Community Health, Brown University, Providence, Rhode Island</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="De Bruyn, Guy" sort="De Bruyn, Guy" uniqKey="De Bruyn G" first="Guy" last="De Bruyn">Guy De Bruyn</name></author><author><name sortKey="Lurie, Mark N" sort="Lurie, Mark N" uniqKey="Lurie M" first="Mark N" last="Lurie">Mark N. Lurie</name></author><author><name sortKey="Mohapi, Lerato" sort="Mohapi, Lerato" uniqKey="Mohapi L" first="Lerato" last="Mohapi">Lerato Mohapi</name></author><author><name sortKey="Pronyk, Paul" sort="Pronyk, Paul" uniqKey="Pronyk P" first="Paul" last="Pronyk">Paul Pronyk</name></author><author><name sortKey="Moshabela, Mosa" sort="Moshabela, Mosa" uniqKey="Moshabela M" first="Mosa" last="Moshabela">Mosa Moshabela</name></author><author><name sortKey="Marinda, Edmore" sort="Marinda, Edmore" uniqKey="Marinda E" first="Edmore" last="Marinda">Edmore Marinda</name></author><author><name sortKey="Gray, Glenda E" sort="Gray, Glenda E" uniqKey="Gray G" first="Glenda E" last="Gray">Glenda E. Gray</name></author><author><name sortKey="Triche, Elizabeth W" sort="Triche, Elizabeth W" uniqKey="Triche E" first="Elizabeth W" last="Triche">Elizabeth W. Triche</name></author><author><name sortKey="Martinson, Neil A" sort="Martinson, Neil A" uniqKey="Martinson N" first="Neil A" last="Martinson">Neil A. Martinson</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:20808202</idno><idno type="pmid">20808202</idno><idno type="doi">10.1097/QAD.0b013e32833e78d4</idno><idno type="wicri:Area/PubMed/Corpus">000220</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000220</idno><idno type="wicri:Area/PubMed/Curation">000220</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000220</idno><idno type="wicri:Area/PubMed/Checkpoint">000220</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000220</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics.</title><author><name sortKey="Venkatesh, Kartik K" sort="Venkatesh, Kartik K" uniqKey="Venkatesh K" first="Kartik K" last="Venkatesh">Kartik K. Venkatesh</name><affiliation wicri:level="4"><nlm:affiliation>Department of Community Health, Brown University, Providence, Rhode Island, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Community Health, Brown University, Providence, Rhode Island</wicri:regionArea><placeName><region type="state">Rhode Island</region><settlement type="city">Providence (Rhode Island)</settlement></placeName><orgName type="university">Université Brown</orgName></affiliation></author><author><name sortKey="De Bruyn, Guy" sort="De Bruyn, Guy" uniqKey="De Bruyn G" first="Guy" last="De Bruyn">Guy De Bruyn</name></author><author><name sortKey="Lurie, Mark N" sort="Lurie, Mark N" uniqKey="Lurie M" first="Mark N" last="Lurie">Mark N. Lurie</name></author><author><name sortKey="Mohapi, Lerato" sort="Mohapi, Lerato" uniqKey="Mohapi L" first="Lerato" last="Mohapi">Lerato Mohapi</name></author><author><name sortKey="Pronyk, Paul" sort="Pronyk, Paul" uniqKey="Pronyk P" first="Paul" last="Pronyk">Paul Pronyk</name></author><author><name sortKey="Moshabela, Mosa" sort="Moshabela, Mosa" uniqKey="Moshabela M" first="Mosa" last="Moshabela">Mosa Moshabela</name></author><author><name sortKey="Marinda, Edmore" sort="Marinda, Edmore" uniqKey="Marinda E" first="Edmore" last="Marinda">Edmore Marinda</name></author><author><name sortKey="Gray, Glenda E" sort="Gray, Glenda E" uniqKey="Gray G" first="Glenda E" last="Gray">Glenda E. Gray</name></author><author><name sortKey="Triche, Elizabeth W" sort="Triche, Elizabeth W" uniqKey="Triche E" first="Elizabeth W" last="Triche">Elizabeth W. Triche</name></author><author><name sortKey="Martinson, Neil A" sort="Martinson, Neil A" uniqKey="Martinson N" first="Neil A" last="Martinson">Neil A. Martinson</name></author></analytic><series><title level="j">AIDS (London, England)</title><idno type="eISSN">1473-5571</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Antiretroviral Therapy, Highly Active</term><term>CD4 Lymphocyte Count</term><term>Female</term><term>HIV Infections (drug therapy)</term><term>HIV Infections (epidemiology)</term><term>HIV Infections (psychology)</term><term>Health Knowledge, Attitudes, Practice</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Patient Acceptance of Health Care (psychology)</term><term>Patient Acceptance of Health Care (statistics & numerical data)</term><term>Primary Health Care (statistics & numerical data)</term><term>Prospective Studies</term><term>Risk-Taking</term><term>Sexual Behavior (psychology)</term><term>South Africa (epidemiology)</term><term>Viral Load</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Acceptation des soins par le patient ()</term><term>Acceptation des soins par le patient (psychologie)</term><term>Adulte</term><term>Charge virale</term><term>Comportement sexuel (psychologie)</term><term>Connaissances, attitudes et pratiques en santé</term><term>Femelle</term><term>Humains</term><term>Infections à VIH (psychologie)</term><term>Infections à VIH (traitement médicamenteux)</term><term>Infections à VIH (épidémiologie)</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prise de risque</term><term>République d'Afrique du Sud (épidémiologie)</term><term>Soins de santé primaires ()</term><term>Thérapie antirétrovirale hautement active</term><term>Études longitudinales</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>South Africa</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Acceptation des soins par le patient</term><term>Comportement sexuel</term><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>HIV Infections</term><term>Patient Acceptance of Health Care</term><term>Sexual Behavior</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Patient Acceptance of Health Care</term><term>Primary Health Care</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à VIH</term><term>République d'Afrique du Sud</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Antiretroviral Therapy, Highly Active</term><term>CD4 Lymphocyte Count</term><term>Female</term><term>Health Knowledge, Attitudes, Practice</term><term>Humans</term><term>Longitudinal Studies</term><term>Male</term><term>Prospective Studies</term><term>Risk-Taking</term><term>Viral Load</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Acceptation des soins par le patient</term><term>Adulte</term><term>Charge virale</term><term>Connaissances, attitudes et pratiques en santé</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Numération des lymphocytes CD4</term><term>Prise de risque</term><term>Soins de santé primaires</term><term>Thérapie antirétrovirale hautement active</term><term>Études longitudinales</term><term>Études prospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Afrique du Sud</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In light of increasing access to HAART in sub-Saharan Africa, we conducted a longitudinal study to assess the impact of HAART on sexual risk behaviors among HIV-infected South Africans in urban and rural primary care clinics.</div></front></TEI></pubmed></double></record>Pour manipuler ce document sous Unix (Dilib)
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