Preventing HIV infection in women: a global health imperative.
Identifieur interne : 000B72 ( Ncbi/Merge ); précédent : 000B71; suivant : 000B73Preventing HIV infection in women: a global health imperative.
Auteurs : Quarraisha Abdool Karim [Afrique du Sud] ; Sengeziwe Sibeko ; Cheryl BaxterSource :
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [ 1537-6591 ] ; 2010.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- methods : Communicable Disease Control.
- prevention & control : HIV Infections.
- transmission : HIV Infections.
- Disease Outbreaks, Female, Humans, Male, Risk Factors, Women's Health.
Abstract
Women account for approximately one-half of all human immunodeficiency virus (HIV) infections worldwide. Sexual transmission is the dominant mode of HIV transmission to women, and there is a concomitant associated epidemic of transmission to infants. The majority of HIV infections in women are in sub-Saharan Africa, with a disproportionate burden in young women <25 years of age. Acquisition and prevention of HIV infection in women is complex and influenced by biological, behavioral, and structural factors. Efforts to reduce the incidence of HIV infection among women in sub-Saharan African could play a substantial role in altering global trajectories of HIV infection. Increasing access to sexual and reproductive health services, addressing gender-based violence and social instability, reducing poverty and the need to engage in sex for survival, and encouraging greater male responsibility are critical short-to-medium-term interventions. Efforts to find a microbicide and HIV vaccine need to be matched with efforts to deepen understanding of acquisition of HIV in the female genital tract to inform development of targeted molecules for prevention of HIV infection.
DOI: 10.1086/651483
PubMed: 20397940
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pubmed:20397940Le document en format XML
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<term>Infections à VIH ()</term>
<term>Infections à VIH (transmission)</term>
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<front><div type="abstract" xml:lang="en">Women account for approximately one-half of all human immunodeficiency virus (HIV) infections worldwide. Sexual transmission is the dominant mode of HIV transmission to women, and there is a concomitant associated epidemic of transmission to infants. The majority of HIV infections in women are in sub-Saharan Africa, with a disproportionate burden in young women <25 years of age. Acquisition and prevention of HIV infection in women is complex and influenced by biological, behavioral, and structural factors. Efforts to reduce the incidence of HIV infection among women in sub-Saharan African could play a substantial role in altering global trajectories of HIV infection. Increasing access to sexual and reproductive health services, addressing gender-based violence and social instability, reducing poverty and the need to engage in sex for survival, and encouraging greater male responsibility are critical short-to-medium-term interventions. Efforts to find a microbicide and HIV vaccine need to be matched with efforts to deepen understanding of acquisition of HIV in the female genital tract to inform development of targeted molecules for prevention of HIV infection.</div>
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<Abstract><AbstractText>Women account for approximately one-half of all human immunodeficiency virus (HIV) infections worldwide. Sexual transmission is the dominant mode of HIV transmission to women, and there is a concomitant associated epidemic of transmission to infants. The majority of HIV infections in women are in sub-Saharan Africa, with a disproportionate burden in young women <25 years of age. Acquisition and prevention of HIV infection in women is complex and influenced by biological, behavioral, and structural factors. Efforts to reduce the incidence of HIV infection among women in sub-Saharan African could play a substantial role in altering global trajectories of HIV infection. Increasing access to sexual and reproductive health services, addressing gender-based violence and social instability, reducing poverty and the need to engage in sex for survival, and encouraging greater male responsibility are critical short-to-medium-term interventions. Efforts to find a microbicide and HIV vaccine need to be matched with efforts to deepen understanding of acquisition of HIV in the female genital tract to inform development of targeted molecules for prevention of HIV infection.</AbstractText>
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<PMID Version="1">17113428</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2007 Feb 24;369(9562):643-56</RefSource>
<PMID Version="1">17321310</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2007 Feb 24;369(9562):657-66</RefSource>
<PMID Version="1">17321311</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>Lancet. 2007 Jul 21;370(9583):251-61</RefSource>
<PMID Version="1">17631387</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites"><RefSource>PLoS Med. 2007 Mar 27;4(3):e102</RefSource>
<PMID Version="1">17388666</PMID>
</CommentsCorrections>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D003140" MajorTopicYN="N">Communicable Disease Control</DescriptorName>
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<MeshHeading><DescriptorName UI="D004196" MajorTopicYN="N">Disease Outbreaks</DescriptorName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading><DescriptorName UI="D016387" MajorTopicYN="Y">Women's Health</DescriptorName>
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<NumberOfReferences>88</NumberOfReferences>
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<affiliations><list><country><li>Afrique du Sud</li>
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<tree><noCountry><name sortKey="Baxter, Cheryl" sort="Baxter, Cheryl" uniqKey="Baxter C" first="Cheryl" last="Baxter">Cheryl Baxter</name>
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