Parasitic diseases of the central nervous system: lessons for clinicians and policy makers
Identifieur interne : 003616 ( Ncbi/Curation ); précédent : 003615; suivant : 003617Parasitic diseases of the central nervous system: lessons for clinicians and policy makers
Auteurs : Arturo Carpio ; Matthew L. Romo ; R. M. E. Parkhouse ; Brooke Short ; Tarun DuaSource :
- Expert Review of Neurotherapeutics [ 1473-7175 ] ; 2016.
Abstract
Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, diagnosis, therapeutic strategies and recent milestones, and aspects related to prevention and control.
Url:
DOI: 10.1586/14737175.2016.1155454
PubMed: 26894629
PubMed Central: 4926779
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<front><div type="abstract" xml:lang="en"><title>ABSTRACT</title>
<p>Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, diagnosis, therapeutic strategies and recent milestones, and aspects related to prevention and control.</p>
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