Le SIDA en Afrique subsaharienne (serveur d'exploration)

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Parasitic diseases of the central nervous system: lessons for clinicians and policy makers

Identifieur interne : 003616 ( Ncbi/Curation ); précédent : 003615; suivant : 003617

Parasitic diseases of the central nervous system: lessons for clinicians and policy makers

Auteurs : Arturo Carpio ; Matthew L. Romo ; R. M. E. Parkhouse ; Brooke Short ; Tarun Dua

Source :

RBID : PMC:4926779

Abstract

ABSTRACT

Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, diagnosis, therapeutic strategies and recent milestones, and aspects related to prevention and control.


Url:
DOI: 10.1586/14737175.2016.1155454
PubMed: 26894629
PubMed Central: 4926779

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PMC:4926779

Le document en format XML

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<p>Parasitic diseases of the central nervous system are associated with high mortality and morbidity, especially in resource-limited settings. The burden of these diseases is amplified as survivors are often left with neurologic sequelae affecting mobility, sensory organs, and cognitive functions, as well as seizures/epilepsy. These diseases inflict suffering by causing lifelong disabilities, reducing economic productivity, and causing social stigma. The complexity of parasitic life cycles and geographic specificities, as well as overlapping clinical manifestations in the host reflecting the diverse pathogenesis of parasites, can present diagnostic challenges. We herein provide an overview of these parasitic diseases and summarize clinical aspects, diagnosis, therapeutic strategies and recent milestones, and aspects related to prevention and control.</p>
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