Le SIDA en Afrique subsaharienne (serveur d'exploration)

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Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.

Identifieur interne : 004427 ( Ncbi/Checkpoint ); précédent : 004426; suivant : 004428

Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.

Auteurs : James Hakim ; Victor Musiime ; Alex J. Szubert ; Jane Mallewa ; Abraham Siika ; Clara Agutu ; Simon Walker ; Sarah L. Pett ; Mutsa Bwakura-Dangarembizi ; Abbas Lugemwa ; Symon Kaunda ; Mercy Karoney ; Godfrey Musoro ; Sheila Kabahenda ; Kusum Nathoo ; Kathryn Maitland ; Anna Griffiths ; Margaret J. Thomason ; Cissy Kityo ; Peter Mugyenyi ; Andrew J. Prendergast ; A Sarah Walker ; Diana M. Gibb

Source :

RBID : pubmed:28723333

Descripteurs français

English descriptors

Abstract

In sub-Saharan Africa, among patients with advanced human immunodeficiency virus (HIV) infection, the rate of death from infection (including tuberculosis and cryptococcus) shortly after the initiation of antiretroviral therapy (ART) is approximately 10%.

DOI: 10.1056/NEJMoa1615822
PubMed: 28723333


Affiliations:


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pubmed:28723333

Le document en format XML

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<name sortKey="Hakim, James" sort="Hakim, James" uniqKey="Hakim J" first="James" last="Hakim">James Hakim</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
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<name sortKey="Musiime, Victor" sort="Musiime, Victor" uniqKey="Musiime V" first="Victor" last="Musiime">Victor Musiime</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
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<name sortKey="Szubert, Alex J" sort="Szubert, Alex J" uniqKey="Szubert A" first="Alex J" last="Szubert">Alex J. Szubert</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
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<name sortKey="Mallewa, Jane" sort="Mallewa, Jane" uniqKey="Mallewa J" first="Jane" last="Mallewa">Jane Mallewa</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
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<author>
<name sortKey="Siika, Abraham" sort="Siika, Abraham" uniqKey="Siika A" first="Abraham" last="Siika">Abraham Siika</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
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<author>
<name sortKey="Agutu, Clara" sort="Agutu, Clara" uniqKey="Agutu C" first="Clara" last="Agutu">Clara Agutu</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Walker, Simon" sort="Walker, Simon" uniqKey="Walker S" first="Simon" last="Walker">Simon Walker</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Pett, Sarah L" sort="Pett, Sarah L" uniqKey="Pett S" first="Sarah L" last="Pett">Sarah L. Pett</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Bwakura Dangarembizi, Mutsa" sort="Bwakura Dangarembizi, Mutsa" uniqKey="Bwakura Dangarembizi M" first="Mutsa" last="Bwakura-Dangarembizi">Mutsa Bwakura-Dangarembizi</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Lugemwa, Abbas" sort="Lugemwa, Abbas" uniqKey="Lugemwa A" first="Abbas" last="Lugemwa">Abbas Lugemwa</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kaunda, Symon" sort="Kaunda, Symon" uniqKey="Kaunda S" first="Symon" last="Kaunda">Symon Kaunda</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Karoney, Mercy" sort="Karoney, Mercy" uniqKey="Karoney M" first="Mercy" last="Karoney">Mercy Karoney</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Musoro, Godfrey" sort="Musoro, Godfrey" uniqKey="Musoro G" first="Godfrey" last="Musoro">Godfrey Musoro</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kabahenda, Sheila" sort="Kabahenda, Sheila" uniqKey="Kabahenda S" first="Sheila" last="Kabahenda">Sheila Kabahenda</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Nathoo, Kusum" sort="Nathoo, Kusum" uniqKey="Nathoo K" first="Kusum" last="Nathoo">Kusum Nathoo</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Maitland, Kathryn" sort="Maitland, Kathryn" uniqKey="Maitland K" first="Kathryn" last="Maitland">Kathryn Maitland</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Griffiths, Anna" sort="Griffiths, Anna" uniqKey="Griffiths A" first="Anna" last="Griffiths">Anna Griffiths</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Thomason, Margaret J" sort="Thomason, Margaret J" uniqKey="Thomason M" first="Margaret J" last="Thomason">Margaret J. Thomason</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kityo, Cissy" sort="Kityo, Cissy" uniqKey="Kityo C" first="Cissy" last="Kityo">Cissy Kityo</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mugyenyi, Peter" sort="Mugyenyi, Peter" uniqKey="Mugyenyi P" first="Peter" last="Mugyenyi">Peter Mugyenyi</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Prendergast, Andrew J" sort="Prendergast, Andrew J" uniqKey="Prendergast A" first="Andrew J" last="Prendergast">Andrew J. Prendergast</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Walker, A Sarah" sort="Walker, A Sarah" uniqKey="Walker A" first="A Sarah" last="Walker">A Sarah Walker</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Gibb, Diana M" sort="Gibb, Diana M" uniqKey="Gibb D" first="Diana M" last="Gibb">Diana M. Gibb</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
</titleStmt>
<publicationStmt>
<idno type="wicri:source">PubMed</idno>
<date when="2017">2017</date>
<idno type="RBID">pubmed:28723333</idno>
<idno type="pmid">28723333</idno>
<idno type="doi">10.1056/NEJMoa1615822</idno>
<idno type="wicri:Area/PubMed/Corpus">000A83</idno>
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<idno type="wicri:Area/PubMed/Checkpoint">000A83</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000A83</idno>
<idno type="wicri:Area/Ncbi/Merge">004427</idno>
<idno type="wicri:Area/Ncbi/Curation">004427</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">004427</idno>
</publicationStmt>
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<analytic>
<title xml:lang="en">Enhanced Prophylaxis plus Antiretroviral Therapy for Advanced HIV Infection in Africa.</title>
<author>
<name sortKey="Hakim, James" sort="Hakim, James" uniqKey="Hakim J" first="James" last="Hakim">James Hakim</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Musiime, Victor" sort="Musiime, Victor" uniqKey="Musiime V" first="Victor" last="Musiime">Victor Musiime</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Szubert, Alex J" sort="Szubert, Alex J" uniqKey="Szubert A" first="Alex J" last="Szubert">Alex J. Szubert</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mallewa, Jane" sort="Mallewa, Jane" uniqKey="Mallewa J" first="Jane" last="Mallewa">Jane Mallewa</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Siika, Abraham" sort="Siika, Abraham" uniqKey="Siika A" first="Abraham" last="Siika">Abraham Siika</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Agutu, Clara" sort="Agutu, Clara" uniqKey="Agutu C" first="Clara" last="Agutu">Clara Agutu</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Walker, Simon" sort="Walker, Simon" uniqKey="Walker S" first="Simon" last="Walker">Simon Walker</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Pett, Sarah L" sort="Pett, Sarah L" uniqKey="Pett S" first="Sarah L" last="Pett">Sarah L. Pett</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Bwakura Dangarembizi, Mutsa" sort="Bwakura Dangarembizi, Mutsa" uniqKey="Bwakura Dangarembizi M" first="Mutsa" last="Bwakura-Dangarembizi">Mutsa Bwakura-Dangarembizi</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Lugemwa, Abbas" sort="Lugemwa, Abbas" uniqKey="Lugemwa A" first="Abbas" last="Lugemwa">Abbas Lugemwa</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kaunda, Symon" sort="Kaunda, Symon" uniqKey="Kaunda S" first="Symon" last="Kaunda">Symon Kaunda</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Karoney, Mercy" sort="Karoney, Mercy" uniqKey="Karoney M" first="Mercy" last="Karoney">Mercy Karoney</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Musoro, Godfrey" sort="Musoro, Godfrey" uniqKey="Musoro G" first="Godfrey" last="Musoro">Godfrey Musoro</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kabahenda, Sheila" sort="Kabahenda, Sheila" uniqKey="Kabahenda S" first="Sheila" last="Kabahenda">Sheila Kabahenda</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Nathoo, Kusum" sort="Nathoo, Kusum" uniqKey="Nathoo K" first="Kusum" last="Nathoo">Kusum Nathoo</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Maitland, Kathryn" sort="Maitland, Kathryn" uniqKey="Maitland K" first="Kathryn" last="Maitland">Kathryn Maitland</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Griffiths, Anna" sort="Griffiths, Anna" uniqKey="Griffiths A" first="Anna" last="Griffiths">Anna Griffiths</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Thomason, Margaret J" sort="Thomason, Margaret J" uniqKey="Thomason M" first="Margaret J" last="Thomason">Margaret J. Thomason</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Kityo, Cissy" sort="Kityo, Cissy" uniqKey="Kityo C" first="Cissy" last="Kityo">Cissy Kityo</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Mugyenyi, Peter" sort="Mugyenyi, Peter" uniqKey="Mugyenyi P" first="Peter" last="Mugyenyi">Peter Mugyenyi</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Prendergast, Andrew J" sort="Prendergast, Andrew J" uniqKey="Prendergast A" first="Andrew J" last="Prendergast">Andrew J. Prendergast</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Walker, A Sarah" sort="Walker, A Sarah" uniqKey="Walker A" first="A Sarah" last="Walker">A Sarah Walker</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
<author>
<name sortKey="Gibb, Diana M" sort="Gibb, Diana M" uniqKey="Gibb D" first="Diana M" last="Gibb">Diana M. Gibb</name>
<affiliation>
<nlm:affiliation>From the University of Zimbabwe Clinical Research Center, Harare, Zimbabwe (J.H., M.B.-D., G.M., K.N.); Joint Clinical Research Center, Kampala (V.M., C.K., P.M.), Mbarara (A.L.), and Fort Portal (S. Kabahenda) - all in Uganda; Medical Research Council Clinical Trials Unit at University College London (A.J.S., S.L.P., A.G., M.J.T., A.S.W., D.M.G.), Wellcome Trust Centre for Clinical Tropical Medicine and Department of Paediatrics, Imperial College (K.M.), and Queen Mary University of London (A.J.P.), London, and the Centre for Health Economics, University of York, York (S.W.) - all in the United Kingdom; the Department of Medicine and Malawi-Liverpool-Wellcome Trust Clinical Research Program, Blantyre, Malawi (J.M., S. Kaunda); and Moi University School of Medicine, Eldoret (A.S., M.K.), and the Kenya Medical Research Institute (KEMRI) Wellcome Trust Research Program, Kilifi (C.A., K.M.) - both in Kenya.</nlm:affiliation>
<wicri:noCountry code="subField">K.M.)</wicri:noCountry>
</affiliation>
</author>
</analytic>
<series>
<title level="j">The New England journal of medicine</title>
<idno type="eISSN">1533-4406</idno>
<imprint>
<date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>AIDS-Related Opportunistic Infections (prevention & control)</term>
<term>Adolescent</term>
<term>Adult</term>
<term>Africa South of the Sahara (epidemiology)</term>
<term>Aged</term>
<term>Anti-Infective Agents (adverse effects)</term>
<term>Anti-Infective Agents (therapeutic use)</term>
<term>Anti-Retroviral Agents (adverse effects)</term>
<term>Anti-Retroviral Agents (therapeutic use)</term>
<term>CD4 Lymphocyte Count</term>
<term>Child</term>
<term>Drug Therapy, Combination</term>
<term>Female</term>
<term>HIV Infections (drug therapy)</term>
<term>HIV Infections (mortality)</term>
<term>Humans</term>
<term>Isoniazid (therapeutic use)</term>
<term>Kaplan-Meier Estimate</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Pyridoxine (therapeutic use)</term>
<term>Trimethoprim, Sulfamethoxazole Drug Combination (therapeutic use)</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Afrique subsaharienne (épidémiologie)</term>
<term>Anti-infectieux (effets indésirables)</term>
<term>Anti-infectieux (usage thérapeutique)</term>
<term>Antirétroviraux (effets indésirables)</term>
<term>Antirétroviraux (usage thérapeutique)</term>
<term>Association de médicaments</term>
<term>Association triméthoprime-sulfaméthoxazole (usage thérapeutique)</term>
<term>Enfant</term>
<term>Estimation de Kaplan-Meier</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infections opportunistes liées au SIDA ()</term>
<term>Infections à VIH (mortalité)</term>
<term>Infections à VIH (traitement médicamenteux)</term>
<term>Isoniazide (usage thérapeutique)</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Numération des lymphocytes CD4</term>
<term>Pyridoxine (usage thérapeutique)</term>
<term>Sujet âgé</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en">
<term>Anti-Infective Agents</term>
<term>Anti-Retroviral Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>HIV Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr">
<term>Anti-infectieux</term>
<term>Antirétroviraux</term>
</keywords>
<keywords scheme="MESH" qualifier="epidemiology" xml:lang="en">
<term>Africa South of the Sahara</term>
</keywords>
<keywords scheme="MESH" qualifier="mortality" xml:lang="en">
<term>HIV Infections</term>
</keywords>
<keywords scheme="MESH" qualifier="mortalité" xml:lang="fr">
<term>Infections à VIH</term>
</keywords>
<keywords scheme="MESH" qualifier="prevention & control" xml:lang="en">
<term>AIDS-Related Opportunistic Infections</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Anti-Infective Agents</term>
<term>Anti-Retroviral Agents</term>
<term>Isoniazid</term>
<term>Pyridoxine</term>
<term>Trimethoprim, Sulfamethoxazole Drug Combination</term>
</keywords>
<keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr">
<term>Infections à VIH</term>
</keywords>
<keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr">
<term>Anti-infectieux</term>
<term>Antirétroviraux</term>
<term>Association triméthoprime-sulfaméthoxazole</term>
<term>Isoniazide</term>
<term>Pyridoxine</term>
</keywords>
<keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr">
<term>Afrique subsaharienne</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>CD4 Lymphocyte Count</term>
<term>Child</term>
<term>Drug Therapy, Combination</term>
<term>Female</term>
<term>Humans</term>
<term>Kaplan-Meier Estimate</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr">
<term>Adolescent</term>
<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Association de médicaments</term>
<term>Enfant</term>
<term>Estimation de Kaplan-Meier</term>
<term>Femelle</term>
<term>Humains</term>
<term>Infections opportunistes liées au SIDA</term>
<term>Jeune adulte</term>
<term>Mâle</term>
<term>Numération des lymphocytes CD4</term>
<term>Sujet âgé</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">In sub-Saharan Africa, among patients with advanced human immunodeficiency virus (HIV) infection, the rate of death from infection (including tuberculosis and cryptococcus) shortly after the initiation of antiretroviral therapy (ART) is approximately 10%.</div>
</front>
</TEI>
<affiliations>
<list></list>
<tree>
<noCountry>
<name sortKey="Agutu, Clara" sort="Agutu, Clara" uniqKey="Agutu C" first="Clara" last="Agutu">Clara Agutu</name>
<name sortKey="Bwakura Dangarembizi, Mutsa" sort="Bwakura Dangarembizi, Mutsa" uniqKey="Bwakura Dangarembizi M" first="Mutsa" last="Bwakura-Dangarembizi">Mutsa Bwakura-Dangarembizi</name>
<name sortKey="Gibb, Diana M" sort="Gibb, Diana M" uniqKey="Gibb D" first="Diana M" last="Gibb">Diana M. Gibb</name>
<name sortKey="Griffiths, Anna" sort="Griffiths, Anna" uniqKey="Griffiths A" first="Anna" last="Griffiths">Anna Griffiths</name>
<name sortKey="Hakim, James" sort="Hakim, James" uniqKey="Hakim J" first="James" last="Hakim">James Hakim</name>
<name sortKey="Kabahenda, Sheila" sort="Kabahenda, Sheila" uniqKey="Kabahenda S" first="Sheila" last="Kabahenda">Sheila Kabahenda</name>
<name sortKey="Karoney, Mercy" sort="Karoney, Mercy" uniqKey="Karoney M" first="Mercy" last="Karoney">Mercy Karoney</name>
<name sortKey="Kaunda, Symon" sort="Kaunda, Symon" uniqKey="Kaunda S" first="Symon" last="Kaunda">Symon Kaunda</name>
<name sortKey="Kityo, Cissy" sort="Kityo, Cissy" uniqKey="Kityo C" first="Cissy" last="Kityo">Cissy Kityo</name>
<name sortKey="Lugemwa, Abbas" sort="Lugemwa, Abbas" uniqKey="Lugemwa A" first="Abbas" last="Lugemwa">Abbas Lugemwa</name>
<name sortKey="Maitland, Kathryn" sort="Maitland, Kathryn" uniqKey="Maitland K" first="Kathryn" last="Maitland">Kathryn Maitland</name>
<name sortKey="Mallewa, Jane" sort="Mallewa, Jane" uniqKey="Mallewa J" first="Jane" last="Mallewa">Jane Mallewa</name>
<name sortKey="Mugyenyi, Peter" sort="Mugyenyi, Peter" uniqKey="Mugyenyi P" first="Peter" last="Mugyenyi">Peter Mugyenyi</name>
<name sortKey="Musiime, Victor" sort="Musiime, Victor" uniqKey="Musiime V" first="Victor" last="Musiime">Victor Musiime</name>
<name sortKey="Musoro, Godfrey" sort="Musoro, Godfrey" uniqKey="Musoro G" first="Godfrey" last="Musoro">Godfrey Musoro</name>
<name sortKey="Nathoo, Kusum" sort="Nathoo, Kusum" uniqKey="Nathoo K" first="Kusum" last="Nathoo">Kusum Nathoo</name>
<name sortKey="Pett, Sarah L" sort="Pett, Sarah L" uniqKey="Pett S" first="Sarah L" last="Pett">Sarah L. Pett</name>
<name sortKey="Prendergast, Andrew J" sort="Prendergast, Andrew J" uniqKey="Prendergast A" first="Andrew J" last="Prendergast">Andrew J. Prendergast</name>
<name sortKey="Siika, Abraham" sort="Siika, Abraham" uniqKey="Siika A" first="Abraham" last="Siika">Abraham Siika</name>
<name sortKey="Szubert, Alex J" sort="Szubert, Alex J" uniqKey="Szubert A" first="Alex J" last="Szubert">Alex J. Szubert</name>
<name sortKey="Thomason, Margaret J" sort="Thomason, Margaret J" uniqKey="Thomason M" first="Margaret J" last="Thomason">Margaret J. Thomason</name>
<name sortKey="Walker, A Sarah" sort="Walker, A Sarah" uniqKey="Walker A" first="A Sarah" last="Walker">A Sarah Walker</name>
<name sortKey="Walker, Simon" sort="Walker, Simon" uniqKey="Walker S" first="Simon" last="Walker">Simon Walker</name>
</noCountry>
</tree>
</affiliations>
</record>

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