Modeling HIV transmission risk among Mozambicans prior to their initiating highly active antiretroviral therapy
Identifieur interne : 000398 ( Ncbi/Checkpoint ); précédent : 000397; suivant : 000399Modeling HIV transmission risk among Mozambicans prior to their initiating highly active antiretroviral therapy
Auteurs : C. R. Pearson [États-Unis] ; A. E. Kurth [États-Unis] ; S. Cassels [États-Unis] ; D. P. Martin [États-Unis] ; J. M. Simoni [États-Unis] ; P. Hoff [États-Unis] ; E. Matediana [Mozambique] ; S. Gloyd [États-Unis]Source :
- AIDS care [ 0954-0121 ] ; 2007.
Abstract
Understanding sexual behavior and assessing transmission risk among people living with HIV-1 is crucial for effective HIV-1 prevention. We describe sexual behavior among HIV-positive persons initiating highly active antiretroviral therapy (HAART) in Beira, Mozambique. We present a Bernoulli process model (tool available online) to estimate the number of sexual partners who would acquire HIV-1 as a consequence of sexual contact with study participants within the prior three months. Baseline data were collected on 350 HAART-naive individuals 18–70 years of age from October 2004 to February 2005. In the three months prior to initiating HAART, 45% (
Url:
DOI: 10.1080/09540120701203337
PubMed: 17505919
PubMed Central: 4226799
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001D83
- to stream Pmc, to step Curation: 001D82
- to stream Pmc, to step Checkpoint: 002B20
- to stream Ncbi, to step Merge: 000398
- to stream Ncbi, to step Curation: 000398
Links to Exploration step
PMC:4226799Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Modeling HIV transmission risk among Mozambicans prior to their initiating highly active antiretroviral therapy</title>
<author><name sortKey="Pearson, C R" sort="Pearson, C R" uniqKey="Pearson C" first="C. R." last="Pearson">C. R. Pearson</name>
<affiliation wicri:level="4"><nlm:aff id="A1">Department of Health Services School of Public Health, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Services School of Public Health, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Kurth, A E" sort="Kurth, A E" uniqKey="Kurth A" first="A. E." last="Kurth">A. E. Kurth</name>
<affiliation wicri:level="4"><nlm:aff id="A2">School of Nursing, Center for AIDS Research, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>School of Nursing, Center for AIDS Research, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Cassels, S" sort="Cassels, S" uniqKey="Cassels S" first="S." last="Cassels">S. Cassels</name>
<affiliation wicri:level="4"><nlm:aff id="A3">Center for AIDS Research, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for AIDS Research, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Martin, D P" sort="Martin, D P" uniqKey="Martin D" first="D. P." last="Martin">D. P. Martin</name>
<affiliation wicri:level="4"><nlm:aff id="A1">Department of Health Services School of Public Health, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Services School of Public Health, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Simoni, J M" sort="Simoni, J M" uniqKey="Simoni J" first="J. M." last="Simoni">J. M. Simoni</name>
<affiliation wicri:level="4"><nlm:aff id="A4">Department of Psychology, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychology, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Hoff, P" sort="Hoff, P" uniqKey="Hoff P" first="P." last="Hoff">P. Hoff</name>
<affiliation wicri:level="4"><nlm:aff id="A5">Department of Statistics, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Statistics, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Matediana, E" sort="Matediana, E" uniqKey="Matediana E" first="E." last="Matediana">E. Matediana</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Ministry of Health, Beira, Mozambique</nlm:aff>
<country xml:lang="fr">Mozambique</country>
<wicri:regionArea>Ministry of Health, Beira</wicri:regionArea>
<wicri:noRegion>Beira</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gloyd, S" sort="Gloyd, S" uniqKey="Gloyd S" first="S." last="Gloyd">S. Gloyd</name>
<affiliation wicri:level="4"><nlm:aff id="A7">International Health Program, Department of Health Services, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>International Health Program, Department of Health Services, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">17505919</idno>
<idno type="pmc">4226799</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226799</idno>
<idno type="RBID">PMC:4226799</idno>
<idno type="doi">10.1080/09540120701203337</idno>
<date when="2007">2007</date>
<idno type="wicri:Area/Pmc/Corpus">001D83</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001D83</idno>
<idno type="wicri:Area/Pmc/Curation">001D82</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001D82</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002B20</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002B20</idno>
<idno type="wicri:Area/Ncbi/Merge">000398</idno>
<idno type="wicri:Area/Ncbi/Curation">000398</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000398</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Modeling HIV transmission risk among Mozambicans prior to their initiating highly active antiretroviral therapy</title>
<author><name sortKey="Pearson, C R" sort="Pearson, C R" uniqKey="Pearson C" first="C. R." last="Pearson">C. R. Pearson</name>
<affiliation wicri:level="4"><nlm:aff id="A1">Department of Health Services School of Public Health, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Services School of Public Health, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Kurth, A E" sort="Kurth, A E" uniqKey="Kurth A" first="A. E." last="Kurth">A. E. Kurth</name>
<affiliation wicri:level="4"><nlm:aff id="A2">School of Nursing, Center for AIDS Research, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>School of Nursing, Center for AIDS Research, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Cassels, S" sort="Cassels, S" uniqKey="Cassels S" first="S." last="Cassels">S. Cassels</name>
<affiliation wicri:level="4"><nlm:aff id="A3">Center for AIDS Research, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Center for AIDS Research, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Martin, D P" sort="Martin, D P" uniqKey="Martin D" first="D. P." last="Martin">D. P. Martin</name>
<affiliation wicri:level="4"><nlm:aff id="A1">Department of Health Services School of Public Health, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Health Services School of Public Health, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Simoni, J M" sort="Simoni, J M" uniqKey="Simoni J" first="J. M." last="Simoni">J. M. Simoni</name>
<affiliation wicri:level="4"><nlm:aff id="A4">Department of Psychology, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Psychology, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Hoff, P" sort="Hoff, P" uniqKey="Hoff P" first="P." last="Hoff">P. Hoff</name>
<affiliation wicri:level="4"><nlm:aff id="A5">Department of Statistics, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Statistics, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
<author><name sortKey="Matediana, E" sort="Matediana, E" uniqKey="Matediana E" first="E." last="Matediana">E. Matediana</name>
<affiliation wicri:level="1"><nlm:aff id="A6">Ministry of Health, Beira, Mozambique</nlm:aff>
<country xml:lang="fr">Mozambique</country>
<wicri:regionArea>Ministry of Health, Beira</wicri:regionArea>
<wicri:noRegion>Beira</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Gloyd, S" sort="Gloyd, S" uniqKey="Gloyd S" first="S." last="Gloyd">S. Gloyd</name>
<affiliation wicri:level="4"><nlm:aff id="A7">International Health Program, Department of Health Services, University of Washington, US</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>International Health Program, Department of Health Services, University of Washington</wicri:regionArea>
<placeName><settlement type="city">Seattle</settlement>
<region type="state">Washington (État)</region>
</placeName>
<orgName type="university">Université de Washington</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">AIDS care</title>
<idno type="ISSN">0954-0121</idno>
<idno type="eISSN">1360-0451</idno>
<imprint><date when="2007">2007</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p id="P1">Understanding sexual behavior and assessing transmission risk among people living with HIV-1 is crucial for effective HIV-1 prevention. We describe sexual behavior among HIV-positive persons initiating highly active antiretroviral therapy (HAART) in Beira, Mozambique. We present a Bernoulli process model (tool available online) to estimate the number of sexual partners who would acquire HIV-1 as a consequence of sexual contact with study participants within the prior three months. Baseline data were collected on 350 HAART-naive individuals 18–70 years of age from October 2004 to February 2005. In the three months prior to initiating HAART, 45% (<italic>n</italic>
= 157) of participants had sexual relationships with 191 partners. Unprotected sex occurred in 70% of partnerships, with evidence suggesting unprotected sex was less likely with partners believed to be HIV-negative. Only 26% of the participants disclosed their serostatus to partners with a negative or unknown serostatus. Women were less likely to report concurrent relationships than were men (21 versus 66%; OR 0.13; 95%CI: 0.06, 0.26). Given baseline behaviors, the model estimated 23.2 infections/1,000 HIV-positive persons per year. The model demonstrated HAART along with syphilis and herpes simplex virus type 2 (HSV-2) treatment combined could reduce HIV-1 transmission by 87%; increasing condom use could reduce HIV-1 transmission by 67%.</p>
</div>
</front>
</TEI>
<affiliations><list><country><li>Mozambique</li>
<li>États-Unis</li>
</country>
<region><li>Washington (État)</li>
</region>
<settlement><li>Seattle</li>
</settlement>
<orgName><li>Université de Washington</li>
</orgName>
</list>
<tree><country name="États-Unis"><region name="Washington (État)"><name sortKey="Pearson, C R" sort="Pearson, C R" uniqKey="Pearson C" first="C. R." last="Pearson">C. R. Pearson</name>
</region>
<name sortKey="Cassels, S" sort="Cassels, S" uniqKey="Cassels S" first="S." last="Cassels">S. Cassels</name>
<name sortKey="Gloyd, S" sort="Gloyd, S" uniqKey="Gloyd S" first="S." last="Gloyd">S. Gloyd</name>
<name sortKey="Hoff, P" sort="Hoff, P" uniqKey="Hoff P" first="P." last="Hoff">P. Hoff</name>
<name sortKey="Kurth, A E" sort="Kurth, A E" uniqKey="Kurth A" first="A. E." last="Kurth">A. E. Kurth</name>
<name sortKey="Martin, D P" sort="Martin, D P" uniqKey="Martin D" first="D. P." last="Martin">D. P. Martin</name>
<name sortKey="Simoni, J M" sort="Simoni, J M" uniqKey="Simoni J" first="J. M." last="Simoni">J. M. Simoni</name>
</country>
<country name="Mozambique"><noRegion><name sortKey="Matediana, E" sort="Matediana, E" uniqKey="Matediana E" first="E." last="Matediana">E. Matediana</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000398 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 000398 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= SidaSubSaharaV1 |flux= Ncbi |étape= Checkpoint |type= RBID |clé= PMC:4226799 |texte= Modeling HIV transmission risk among Mozambicans prior to their initiating highly active antiretroviral therapy }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:17505919" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \ | NlmPubMed2Wicri -a SidaSubSaharaV1
This area was generated with Dilib version V0.6.32. |