SidaSubSaharaV1, Main, Merge, bibRecord, 000031

Virologic outcomes in early antiretroviral treatment: HPTN 052.

Identifieur interne : 000031 ( Main/Merge ); précédent : 000030; suivant : 000032

Virologic outcomes in early antiretroviral treatment: HPTN 052.

Auteurs : Susan H. Eshleman [États-Unis] ; Ethan A. Wilson [États-Unis] ; Xinyi C. Zhang [États-Unis] ; San-San Ou [États-Unis] ; Estelle Piwowar-Manning [États-Unis] ; Joseph J. Eron [États-Unis] ; Marybeth Mccauley [États-Unis] ; Theresa Gamble [États-Unis] ; Joel E. Gallant [États-Unis] ; Mina C. Hosseinipour [États-Unis] ; Nagalingeswaran Kumarasamy [Inde] ; James G. Hakim [Zimbabwe] ; Ben Kalonga [Malawi] ; Jose H. Pilotto [Brésil] ; Beatriz Grinsztejn [Brésil] ; Sheela V. Godbole [Inde] ; Nuntisa Chotirosniramit [Thaïlande] ; Breno Riegel Santos [Brésil] ; Emily Shava [Botswana] ; Lisa A. Mills [Kenya] ; Ravindre Panchia [Afrique du Sud] ; Noluthando Mwelase [Afrique du Sud] ; Kenneth H. Mayer [États-Unis] ; Ying Q. Chen [États-Unis] ; Myron S. Cohen [États-Unis] ; Jessica M. Fogel [États-Unis]

Source :

HIV clinical trials [ 1945-5771 ] ; 2017.

RBID : pubmed:28385131

Abstract

The HIV Prevention Trials Network (HPTN) 052 trial demonstrated that early antiretroviral therapy (ART) prevented 93% of HIV transmission events in serodiscordant couples. Some linked infections were observed shortly after ART initiation or after virologic failure.

DOI: 10.1080/15284336.2017.1311056
PubMed: 28385131

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<author><name sortKey="Gallant, Joel E" sort="Gallant, Joel E" uniqKey="Gallant J" first="Joel E" last="Gallant">Joel E. Gallant</name>
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<author><name sortKey="Hosseinipour, Mina C" sort="Hosseinipour, Mina C" uniqKey="Hosseinipour M" first="Mina C" last="Hosseinipour">Mina C. Hosseinipour</name>
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<author><name sortKey="Kumarasamy, Nagalingeswaran" sort="Kumarasamy, Nagalingeswaran" uniqKey="Kumarasamy N" first="Nagalingeswaran" last="Kumarasamy">Nagalingeswaran Kumarasamy</name>
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<author><name sortKey="Grinsztejn, Beatriz" sort="Grinsztejn, Beatriz" uniqKey="Grinsztejn B" first="Beatriz" last="Grinsztejn">Beatriz Grinsztejn</name>
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<author><name sortKey="Godbole, Sheela V" sort="Godbole, Sheela V" uniqKey="Godbole S" first="Sheela V" last="Godbole">Sheela V. Godbole</name>
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<author><name sortKey="Chotirosniramit, Nuntisa" sort="Chotirosniramit, Nuntisa" uniqKey="Chotirosniramit N" first="Nuntisa" last="Chotirosniramit">Nuntisa Chotirosniramit</name>
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<author><name sortKey="Santos, Breno Riegel" sort="Santos, Breno Riegel" uniqKey="Santos B" first="Breno Riegel" last="Santos">Breno Riegel Santos</name>
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<author><name sortKey="Shava, Emily" sort="Shava, Emily" uniqKey="Shava E" first="Emily" last="Shava">Emily Shava</name>
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<author><name sortKey="Panchia, Ravindre" sort="Panchia, Ravindre" uniqKey="Panchia R" first="Ravindre" last="Panchia">Ravindre Panchia</name>
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<author><name sortKey="Mwelase, Noluthando" sort="Mwelase, Noluthando" uniqKey="Mwelase N" first="Noluthando" last="Mwelase">Noluthando Mwelase</name>
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<author><name sortKey="Mayer, Kenneth H" sort="Mayer, Kenneth H" uniqKey="Mayer K" first="Kenneth H" last="Mayer">Kenneth H. Mayer</name>
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<author><name sortKey="Chen, Ying Q" sort="Chen, Ying Q" uniqKey="Chen Y" first="Ying Q" last="Chen">Ying Q. Chen</name>
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<author><name sortKey="Cohen, Myron S" sort="Cohen, Myron S" uniqKey="Cohen M" first="Myron S" last="Cohen">Myron S. Cohen</name>
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<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fogel, Jessica M" sort="Fogel, Jessica M" uniqKey="Fogel J" first="Jessica M" last="Fogel">Jessica M. Fogel</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Virologic outcomes in early antiretroviral treatment: HPTN 052.</title>
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<author><name sortKey="Wilson, Ethan A" sort="Wilson, Ethan A" uniqKey="Wilson E" first="Ethan A" last="Wilson">Ethan A. Wilson</name>
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<author><name sortKey="Ou, San San" sort="Ou, San San" uniqKey="Ou S" first="San-San" last="Ou">San-San Ou</name>
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<author><name sortKey="Piwowar Manning, Estelle" sort="Piwowar Manning, Estelle" uniqKey="Piwowar Manning E" first="Estelle" last="Piwowar-Manning">Estelle Piwowar-Manning</name>
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<author><name sortKey="Eron, Joseph J" sort="Eron, Joseph J" uniqKey="Eron J" first="Joseph J" last="Eron">Joseph J. Eron</name>
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<author><name sortKey="Mccauley, Marybeth" sort="Mccauley, Marybeth" uniqKey="Mccauley M" first="Marybeth" last="Mccauley">Marybeth Mccauley</name>
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<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Gamble, Theresa" sort="Gamble, Theresa" uniqKey="Gamble T" first="Theresa" last="Gamble">Theresa Gamble</name>
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<country xml:lang="fr">États-Unis</country>
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<placeName><region type="state">Caroline du Nord</region>
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<author><name sortKey="Gallant, Joel E" sort="Gallant, Joel E" uniqKey="Gallant J" first="Joel E" last="Gallant">Joel E. Gallant</name>
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<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Hosseinipour, Mina C" sort="Hosseinipour, Mina C" uniqKey="Hosseinipour M" first="Mina C" last="Hosseinipour">Mina C. Hosseinipour</name>
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<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Kumarasamy, Nagalingeswaran" sort="Kumarasamy, Nagalingeswaran" uniqKey="Kumarasamy N" first="Nagalingeswaran" last="Kumarasamy">Nagalingeswaran Kumarasamy</name>
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<country xml:lang="fr">Inde</country>
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</author>
<author><name sortKey="Hakim, James G" sort="Hakim, James G" uniqKey="Hakim J" first="James G" last="Hakim">James G. Hakim</name>
<affiliation wicri:level="1"><nlm:affiliation>j Department of Medicine , University of Zimbabwe , Harare , Zimbabwe.</nlm:affiliation>
<country xml:lang="fr">Zimbabwe</country>
<wicri:regionArea>j Department of Medicine , University of Zimbabwe , Harare </wicri:regionArea>
<wicri:noRegion>Harare </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Kalonga, Ben" sort="Kalonga, Ben" uniqKey="Kalonga B" first="Ben" last="Kalonga">Ben Kalonga</name>
<affiliation wicri:level="1"><nlm:affiliation>k College of Medicine-Johns Hopkins Project , Blantyre , Malawi.</nlm:affiliation>
<country xml:lang="fr">Malawi</country>
<wicri:regionArea>k College of Medicine-Johns Hopkins Project , Blantyre </wicri:regionArea>
<wicri:noRegion>Blantyre </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Pilotto, Jose H" sort="Pilotto, Jose H" uniqKey="Pilotto J" first="Jose H" last="Pilotto">Jose H. Pilotto</name>
<affiliation wicri:level="1"><nlm:affiliation>l Hospital Geral de Nova Iguacu and Laboratorio de AIDS e Imunologia Molecular-IOC/Fiocruz , Rio de Janeiro , Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>l Hospital Geral de Nova Iguacu and Laboratorio de AIDS e Imunologia Molecular-IOC/Fiocruz , Rio de Janeiro </wicri:regionArea>
<wicri:noRegion>Rio de Janeiro </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Grinsztejn, Beatriz" sort="Grinsztejn, Beatriz" uniqKey="Grinsztejn B" first="Beatriz" last="Grinsztejn">Beatriz Grinsztejn</name>
<affiliation wicri:level="1"><nlm:affiliation>m Instituto Nacional de Infectologia Evandro Chagas-INI-Fiocruz , Rio de Janeiro , Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>m Instituto Nacional de Infectologia Evandro Chagas-INI-Fiocruz , Rio de Janeiro </wicri:regionArea>
<wicri:noRegion>Rio de Janeiro </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Godbole, Sheela V" sort="Godbole, Sheela V" uniqKey="Godbole S" first="Sheela V" last="Godbole">Sheela V. Godbole</name>
<affiliation wicri:level="1"><nlm:affiliation>n National AIDS Research Institute (ICMR) , Pune , India.</nlm:affiliation>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>n National AIDS Research Institute (ICMR) , Pune </wicri:regionArea>
<wicri:noRegion>Pune </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chotirosniramit, Nuntisa" sort="Chotirosniramit, Nuntisa" uniqKey="Chotirosniramit N" first="Nuntisa" last="Chotirosniramit">Nuntisa Chotirosniramit</name>
<affiliation wicri:level="1"><nlm:affiliation>o Research Institute for Health Sciences, Chiang Mai University , Chiang Mai , Thailand.</nlm:affiliation>
<country xml:lang="fr">Thaïlande</country>
<wicri:regionArea>o Research Institute for Health Sciences, Chiang Mai University , Chiang Mai </wicri:regionArea>
<wicri:noRegion>Chiang Mai </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Santos, Breno Riegel" sort="Santos, Breno Riegel" uniqKey="Santos B" first="Breno Riegel" last="Santos">Breno Riegel Santos</name>
<affiliation wicri:level="1"><nlm:affiliation>p Hospital Nossa Senhora da Conceição , Porto Alegre , Brazil.</nlm:affiliation>
<country xml:lang="fr">Brésil</country>
<wicri:regionArea>p Hospital Nossa Senhora da Conceição , Porto Alegre </wicri:regionArea>
<wicri:noRegion>Porto Alegre </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shava, Emily" sort="Shava, Emily" uniqKey="Shava E" first="Emily" last="Shava">Emily Shava</name>
<affiliation wicri:level="1"><nlm:affiliation>q Botswana Harvard AIDS Institute , Gaborone , Botswana.</nlm:affiliation>
<country xml:lang="fr">Botswana</country>
<wicri:regionArea>q Botswana Harvard AIDS Institute , Gaborone </wicri:regionArea>
<wicri:noRegion>Gaborone </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mills, Lisa A" sort="Mills, Lisa A" uniqKey="Mills L" first="Lisa A" last="Mills">Lisa A. Mills</name>
<affiliation wicri:level="1"><nlm:affiliation>r Centers for Disease Control and Prevention, Division of HIV/AIDS Prevention and Kenya Medical Research Institute (KEMRI)/CDC Clinical Research Site , Kisumu , Kenya.</nlm:affiliation>
<country xml:lang="fr">Kenya</country>
<wicri:regionArea>r Centers for Disease Control and Prevention, Division of HIV/AIDS Prevention and Kenya Medical Research Institute (KEMRI)/CDC Clinical Research Site , Kisumu </wicri:regionArea>
<wicri:noRegion>Kisumu </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Panchia, Ravindre" sort="Panchia, Ravindre" uniqKey="Panchia R" first="Ravindre" last="Panchia">Ravindre Panchia</name>
<affiliation wicri:level="4"><nlm:affiliation>s University of the Witwatersrand, Perinatal HIV Research Unit, Soweto HPTN CRS , Soweto , South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>s University of the Witwatersrand, Perinatal HIV Research Unit, Soweto HPTN CRS , Soweto </wicri:regionArea>
<orgName type="university">Université du Witwatersrand</orgName>
<placeName><settlement type="city">Johannesbourg</settlement>
<region type="region" nuts="2">Gauteng</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mwelase, Noluthando" sort="Mwelase, Noluthando" uniqKey="Mwelase N" first="Noluthando" last="Mwelase">Noluthando Mwelase</name>
<affiliation wicri:level="1"><nlm:affiliation>t Clinical HIV Research Unit, Department of Medicine , University of the Witwatersrand , Johannesburg , South Africa.</nlm:affiliation>
<country xml:lang="fr">Afrique du Sud</country>
<wicri:regionArea>t Clinical HIV Research Unit, Department of Medicine , University of the Witwatersrand , Johannesburg </wicri:regionArea>
<wicri:noRegion>Johannesburg </wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mayer, Kenneth H" sort="Mayer, Kenneth H" uniqKey="Mayer K" first="Kenneth H" last="Mayer">Kenneth H. Mayer</name>
<affiliation wicri:level="2"><nlm:affiliation>u The Fenway Institute, Fenway Health/Infectious Disease Division, Beth Israel Deaconess Medical Center, Department of Medicine , Harvard Medical School , Boston , MA , USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>u The Fenway Institute, Fenway Health/Infectious Disease Division, Beth Israel Deaconess Medical Center, Department of Medicine , Harvard Medical School , Boston , MA </wicri:regionArea>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chen, Ying Q" sort="Chen, Ying Q" uniqKey="Chen Y" first="Ying Q" last="Chen">Ying Q. Chen</name>
<affiliation wicri:level="2"><nlm:affiliation>b Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center , Seattle , WA , USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>b Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center , Seattle , WA </wicri:regionArea>
<placeName><region type="state">Washington (État)</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cohen, Myron S" sort="Cohen, Myron S" uniqKey="Cohen M" first="Myron S" last="Cohen">Myron S. Cohen</name>
<affiliation wicri:level="2"><nlm:affiliation>c Department of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , NC , USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>c Department of Medicine , University of North Carolina at Chapel Hill , Chapel Hill , NC </wicri:regionArea>
<placeName><region type="state">Caroline du Nord</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fogel, Jessica M" sort="Fogel, Jessica M" uniqKey="Fogel J" first="Jessica M" last="Fogel">Jessica M. Fogel</name>
<affiliation wicri:level="2"><nlm:affiliation>a Department of Pathology , Johns Hopkins University School of Medicine , Baltimore , MD , USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>a Department of Pathology , Johns Hopkins University School of Medicine , Baltimore , MD </wicri:regionArea>
<placeName><region type="state">Maryland</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">HIV clinical trials</title>
<idno type="eISSN">1945-5771</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The HIV Prevention Trials Network (HPTN) 052 trial demonstrated that early antiretroviral therapy (ART) prevented 93% of HIV transmission events in serodiscordant couples. Some linked infections were observed shortly after ART initiation or after virologic failure.</div>
</front>
</TEI>
</record>

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	Le SIDA en Afrique subsaharienne (serveur d'exploration)
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Le SIDA en Afrique subsaharienne (serveur d'exploration)

Virologic outcomes in early antiretroviral treatment: HPTN 052.

Virologic outcomes in early antiretroviral treatment: HPTN 052.

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