Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study.
Identifieur interne : 004960 ( Main/Exploration ); précédent : 004959; suivant : 004961Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study.
Auteurs : Keertan Dheda [Afrique du Sud] ; Karen Shean ; Alimuddin Zumla ; Motasim Badri ; Elizabeth M. Streicher ; Liesl Page-Shipp ; Paul Willcox ; Melanie-Anne John ; Gary Reubenson ; Darshini Govindasamy ; Michelle Wong ; Xavier Padanilam ; Alicia Dziwiecki ; Paul D. Van Helden ; Sweetness Siwendu ; Julie Jarand ; Colin N. Menezes ; Avril Burns ; Thomas Victor ; Robin Warren ; Martin P. Grobusch ; Martie Van Der Walt ; Charlotte KvasnovskySource :
- Lancet (London, England) [ 1474-547X ] ; 2010.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Antituberculeux (effets indésirables), Antituberculeux (usage thérapeutique), Humains, Infections opportunistes liées au SIDA (traitement médicamenteux), Infections à VIH (), Infections à VIH (traitement médicamenteux), République d'Afrique du Sud, Résultat thérapeutique, Taux de survie, Tests de sensibilité microbienne, Thérapie antirétrovirale hautement active, Tuberculose multirésistante (traitement médicamenteux), Tuberculose ultrarésistante aux médicaments (), Tuberculose ultrarésistante aux médicaments (mortalité), Tuberculose ultrarésistante aux médicaments (traitement médicamenteux).
- MESH :
- effets indésirables : Antituberculeux.
- mortalité : Tuberculose ultrarésistante aux médicaments.
- traitement médicamenteux : Infections opportunistes liées au SIDA, Infections à VIH, Tuberculose multirésistante, Tuberculose ultrarésistante aux médicaments.
- usage thérapeutique : Antituberculeux.
- Adulte, Adulte d'âge moyen, Humains, Infections à VIH, République d'Afrique du Sud, Résultat thérapeutique, Taux de survie, Tests de sensibilité microbienne, Thérapie antirétrovirale hautement active, Tuberculose ultrarésistante aux médicaments.
- Wicri :
- geographic : Afrique du Sud.
English descriptors
- KwdEn :
- AIDS-Related Opportunistic Infections (drug therapy), Adult, Antiretroviral Therapy, Highly Active, Antitubercular Agents (adverse effects), Antitubercular Agents (therapeutic use), Extensively Drug-Resistant Tuberculosis (complications), Extensively Drug-Resistant Tuberculosis (drug therapy), Extensively Drug-Resistant Tuberculosis (mortality), HIV Infections (complications), HIV Infections (drug therapy), Humans, Microbial Sensitivity Tests, Middle Aged, South Africa, Survival Rate, Treatment Outcome, Tuberculosis, Multidrug-Resistant (drug therapy).
- MESH :
- chemical , adverse effects : Antitubercular Agents.
- geographic : South Africa.
- complications : Extensively Drug-Resistant Tuberculosis, HIV Infections.
- drug therapy : AIDS-Related Opportunistic Infections, Extensively Drug-Resistant Tuberculosis, HIV Infections, Tuberculosis, Multidrug-Resistant.
- mortality : Extensively Drug-Resistant Tuberculosis.
- chemical , therapeutic use : Antitubercular Agents.
- Adult, Antiretroviral Therapy, Highly Active, Humans, Microbial Sensitivity Tests, Middle Aged, Survival Rate, Treatment Outcome.
Abstract
Data from Kwazulu Natal, South Africa, suggest that almost all patients with extensively drug-resistant (XDR) tuberculosis are HIV-positive, with a fatal outcome. Since, there are few data for the treatment-related outcomes of XDR tuberculosis in settings with a high HIV prevalence, we investigated the associations of these diseases in such settings to formulate recommendations for control programmes.
DOI: 10.1016/S0140-6736(10)60492-8
PubMed: 20488525
Affiliations:
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Le document en format XML
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Streicher</name></author><author><name sortKey="Page Shipp, Liesl" sort="Page Shipp, Liesl" uniqKey="Page Shipp L" first="Liesl" last="Page-Shipp">Liesl Page-Shipp</name></author><author><name sortKey="Willcox, Paul" sort="Willcox, Paul" uniqKey="Willcox P" first="Paul" last="Willcox">Paul Willcox</name></author><author><name sortKey="John, Melanie Anne" sort="John, Melanie Anne" uniqKey="John M" first="Melanie-Anne" last="John">Melanie-Anne John</name></author><author><name sortKey="Reubenson, Gary" sort="Reubenson, Gary" uniqKey="Reubenson G" first="Gary" last="Reubenson">Gary Reubenson</name></author><author><name sortKey="Govindasamy, Darshini" sort="Govindasamy, Darshini" uniqKey="Govindasamy D" first="Darshini" last="Govindasamy">Darshini Govindasamy</name></author><author><name sortKey="Wong, Michelle" sort="Wong, Michelle" uniqKey="Wong M" first="Michelle" last="Wong">Michelle Wong</name></author><author><name sortKey="Padanilam, Xavier" sort="Padanilam, Xavier" uniqKey="Padanilam X" first="Xavier" last="Padanilam">Xavier Padanilam</name></author><author><name sortKey="Dziwiecki, Alicia" sort="Dziwiecki, Alicia" uniqKey="Dziwiecki A" first="Alicia" last="Dziwiecki">Alicia Dziwiecki</name></author><author><name sortKey="Van Helden, Paul D" sort="Van Helden, Paul D" uniqKey="Van Helden P" first="Paul D" last="Van Helden">Paul D. Van Helden</name></author><author><name sortKey="Siwendu, Sweetness" sort="Siwendu, Sweetness" uniqKey="Siwendu S" first="Sweetness" last="Siwendu">Sweetness Siwendu</name></author><author><name sortKey="Jarand, Julie" sort="Jarand, Julie" uniqKey="Jarand J" first="Julie" last="Jarand">Julie Jarand</name></author><author><name sortKey="Menezes, Colin N" sort="Menezes, Colin N" uniqKey="Menezes C" first="Colin N" last="Menezes">Colin N. Menezes</name></author><author><name sortKey="Burns, Avril" sort="Burns, Avril" uniqKey="Burns A" first="Avril" last="Burns">Avril Burns</name></author><author><name sortKey="Victor, Thomas" sort="Victor, Thomas" uniqKey="Victor T" first="Thomas" last="Victor">Thomas Victor</name></author><author><name sortKey="Warren, Robin" sort="Warren, Robin" uniqKey="Warren R" first="Robin" last="Warren">Robin Warren</name></author><author><name sortKey="Grobusch, Martin P" sort="Grobusch, Martin P" uniqKey="Grobusch M" first="Martin P" last="Grobusch">Martin P. Grobusch</name></author><author><name sortKey="Van Der Walt, Martie" sort="Van Der Walt, Martie" uniqKey="Van Der Walt M" first="Martie" last="Van Der Walt">Martie Van Der Walt</name></author><author><name sortKey="Kvasnovsky, Charlotte" sort="Kvasnovsky, Charlotte" uniqKey="Kvasnovsky C" first="Charlotte" last="Kvasnovsky">Charlotte Kvasnovsky</name></author></analytic><series><title level="j">Lancet (London, England)</title><idno type="eISSN">1474-547X</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>AIDS-Related Opportunistic Infections (drug therapy)</term><term>Adult</term><term>Antiretroviral Therapy, Highly Active</term><term>Antitubercular Agents (adverse effects)</term><term>Antitubercular Agents (therapeutic use)</term><term>Extensively Drug-Resistant Tuberculosis (complications)</term><term>Extensively Drug-Resistant Tuberculosis (drug therapy)</term><term>Extensively Drug-Resistant Tuberculosis (mortality)</term><term>HIV Infections (complications)</term><term>HIV Infections (drug therapy)</term><term>Humans</term><term>Microbial Sensitivity Tests</term><term>Middle Aged</term><term>South Africa</term><term>Survival Rate</term><term>Treatment Outcome</term><term>Tuberculosis, Multidrug-Resistant (drug therapy)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Antituberculeux (effets indésirables)</term><term>Antituberculeux (usage thérapeutique)</term><term>Humains</term><term>Infections opportunistes liées au SIDA (traitement médicamenteux)</term><term>Infections à VIH ()</term><term>Infections à VIH (traitement médicamenteux)</term><term>République d'Afrique du Sud</term><term>Résultat thérapeutique</term><term>Taux de survie</term><term>Tests de sensibilité microbienne</term><term>Thérapie antirétrovirale hautement active</term><term>Tuberculose multirésistante (traitement médicamenteux)</term><term>Tuberculose ultrarésistante aux médicaments ()</term><term>Tuberculose ultrarésistante aux médicaments (mortalité)</term><term>Tuberculose ultrarésistante aux médicaments (traitement médicamenteux)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antitubercular Agents</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>South Africa</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Extensively Drug-Resistant Tuberculosis</term><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>AIDS-Related Opportunistic Infections</term><term>Extensively Drug-Resistant Tuberculosis</term><term>HIV Infections</term><term>Tuberculosis, Multidrug-Resistant</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Antituberculeux</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Extensively Drug-Resistant Tuberculosis</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Tuberculose ultrarésistante aux médicaments</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antitubercular Agents</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections opportunistes liées au SIDA</term><term>Infections à VIH</term><term>Tuberculose multirésistante</term><term>Tuberculose ultrarésistante aux médicaments</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antituberculeux</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Antiretroviral Therapy, Highly Active</term><term>Humans</term><term>Microbial Sensitivity Tests</term><term>Middle Aged</term><term>Survival Rate</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Humains</term><term>Infections à VIH</term><term>République d'Afrique du Sud</term><term>Résultat thérapeutique</term><term>Taux de survie</term><term>Tests de sensibilité microbienne</term><term>Thérapie antirétrovirale hautement active</term><term>Tuberculose ultrarésistante aux médicaments</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Afrique du Sud</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Data from Kwazulu Natal, South Africa, suggest that almost all patients with extensively drug-resistant (XDR) tuberculosis are HIV-positive, with a fatal outcome. Since, there are few data for the treatment-related outcomes of XDR tuberculosis in settings with a high HIV prevalence, we investigated the associations of these diseases in such settings to formulate recommendations for control programmes.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li></country></list><tree><noCountry><name sortKey="Badri, Motasim" sort="Badri, Motasim" uniqKey="Badri M" first="Motasim" last="Badri">Motasim Badri</name><name sortKey="Burns, Avril" sort="Burns, Avril" uniqKey="Burns A" first="Avril" last="Burns">Avril Burns</name><name sortKey="Dziwiecki, Alicia" sort="Dziwiecki, Alicia" uniqKey="Dziwiecki A" first="Alicia" last="Dziwiecki">Alicia Dziwiecki</name><name sortKey="Govindasamy, Darshini" sort="Govindasamy, Darshini" uniqKey="Govindasamy D" first="Darshini" last="Govindasamy">Darshini Govindasamy</name><name sortKey="Grobusch, Martin P" sort="Grobusch, Martin P" uniqKey="Grobusch M" first="Martin P" last="Grobusch">Martin P. Grobusch</name><name sortKey="Jarand, Julie" sort="Jarand, Julie" uniqKey="Jarand J" first="Julie" last="Jarand">Julie Jarand</name><name sortKey="John, Melanie Anne" sort="John, Melanie Anne" uniqKey="John M" first="Melanie-Anne" last="John">Melanie-Anne John</name><name sortKey="Kvasnovsky, Charlotte" sort="Kvasnovsky, Charlotte" uniqKey="Kvasnovsky C" first="Charlotte" last="Kvasnovsky">Charlotte Kvasnovsky</name><name sortKey="Menezes, Colin N" sort="Menezes, Colin N" uniqKey="Menezes C" first="Colin N" last="Menezes">Colin N. Menezes</name><name sortKey="Padanilam, Xavier" sort="Padanilam, Xavier" uniqKey="Padanilam X" first="Xavier" last="Padanilam">Xavier Padanilam</name><name sortKey="Page Shipp, Liesl" sort="Page Shipp, Liesl" uniqKey="Page Shipp L" first="Liesl" last="Page-Shipp">Liesl Page-Shipp</name><name sortKey="Reubenson, Gary" sort="Reubenson, Gary" uniqKey="Reubenson G" first="Gary" last="Reubenson">Gary Reubenson</name><name sortKey="Shean, Karen" sort="Shean, Karen" uniqKey="Shean K" first="Karen" last="Shean">Karen Shean</name><name sortKey="Siwendu, Sweetness" sort="Siwendu, Sweetness" uniqKey="Siwendu S" first="Sweetness" last="Siwendu">Sweetness Siwendu</name><name sortKey="Streicher, Elizabeth M" sort="Streicher, Elizabeth M" uniqKey="Streicher E" first="Elizabeth M" last="Streicher">Elizabeth M. Streicher</name><name sortKey="Van Der Walt, Martie" sort="Van Der Walt, Martie" uniqKey="Van Der Walt M" first="Martie" last="Van Der Walt">Martie Van Der Walt</name><name sortKey="Van Helden, Paul D" sort="Van Helden, Paul D" uniqKey="Van Helden P" first="Paul D" last="Van Helden">Paul D. Van Helden</name><name sortKey="Victor, Thomas" sort="Victor, Thomas" uniqKey="Victor T" first="Thomas" last="Victor">Thomas Victor</name><name sortKey="Warren, Robin" sort="Warren, Robin" uniqKey="Warren R" first="Robin" last="Warren">Robin Warren</name><name sortKey="Willcox, Paul" sort="Willcox, Paul" uniqKey="Willcox P" first="Paul" last="Willcox">Paul Willcox</name><name sortKey="Wong, Michelle" sort="Wong, Michelle" uniqKey="Wong M" first="Michelle" last="Wong">Michelle Wong</name><name sortKey="Zumla, Alimuddin" sort="Zumla, Alimuddin" uniqKey="Zumla A" first="Alimuddin" last="Zumla">Alimuddin Zumla</name></noCountry><country name="Afrique du Sud"><noRegion><name sortKey="Dheda, Keertan" sort="Dheda, Keertan" uniqKey="Dheda K" first="Keertan" last="Dheda">Keertan Dheda</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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