Antiretroviral Treatment Adherence: Knowledge and Experiences among Adolescents and Young Adults in Soweto, South Africa
Identifieur interne : 000B40 ( Main/Exploration ); précédent : 000B39; suivant : 000B41Antiretroviral Treatment Adherence: Knowledge and Experiences among Adolescents and Young Adults in Soweto, South Africa
Auteurs : Stefanie Hornschuh [Afrique du Sud] ; Janan Janine Dietrich [Afrique du Sud] ; Celokuhle Tshabalala [Afrique du Sud] ; Fatima Laher [Afrique du Sud]Source :
- AIDS Research and Treatment [ 2090-1240 ] ; 2017.
Abstract
Human immunodeficiency virus (HIV) management of adolescents and young adults (AYAs) is particularly pertinent to sub-Saharan Africa, where the pediatric HIV burden is marked. Antiretroviral treatment (ART) adherence is a major challenge for AYAs. This qualitative study explored knowledge and experiences of adherence amongst AYAs attending treatment at the Perinatal HIV Research Unit (PHRU), Soweto, South Africa. Four focus group discussions (FGDs) and eight in-depth interviews (IDIs) were conducted with HIV-infected 15–25-year-old ART recipients. Transcripts were coded thematically. Participants (
Url:
DOI: 10.1155/2017/5192516
PubMed: 28409026
PubMed Central: 5376918
Affiliations:
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type="wicri:Area/Main/Curation">000B40</idno><idno type="wicri:Area/Main/Exploration">000B40</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Antiretroviral Treatment Adherence: Knowledge and Experiences among Adolescents and Young Adults in Soweto, South Africa</title><author><name sortKey="Hornschuh, Stefanie" sort="Hornschuh, Stefanie" uniqKey="Hornschuh S" first="Stefanie" last="Hornschuh">Stefanie Hornschuh</name><affiliation wicri:level="4"><nlm:aff id="I1">Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Dietrich, Janan Janine" sort="Dietrich, Janan Janine" uniqKey="Dietrich J" first="Janan Janine" last="Dietrich">Janan Janine Dietrich</name><affiliation wicri:level="4"><nlm:aff id="I1">Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Tshabalala, Celokuhle" sort="Tshabalala, Celokuhle" uniqKey="Tshabalala C" first="Celokuhle" last="Tshabalala">Celokuhle Tshabalala</name><affiliation wicri:level="4"><nlm:aff id="I1">Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author><author><name sortKey="Laher, Fatima" sort="Laher, Fatima" uniqKey="Laher F" first="Fatima" last="Laher">Fatima Laher</name><affiliation wicri:level="4"><nlm:aff id="I1">Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864, South Africa</nlm:aff><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Perinatal HIV Research Unit, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Gauteng 1864</wicri:regionArea><orgName type="university">Université du Witwatersrand</orgName><placeName><settlement type="city">Johannesbourg</settlement><region type="region" nuts="2">Gauteng</region></placeName></affiliation></author></analytic><series><title level="j">AIDS Research and Treatment</title><idno type="ISSN">2090-1240</idno><idno type="eISSN">2090-1259</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Human immunodeficiency virus (HIV) management of adolescents and young adults (AYAs) is particularly pertinent to sub-Saharan Africa, where the pediatric HIV burden is marked. Antiretroviral treatment (ART) adherence is a major challenge for AYAs. This qualitative study explored knowledge and experiences of adherence amongst AYAs attending treatment at the Perinatal HIV Research Unit (PHRU), Soweto, South Africa. Four focus group discussions (FGDs) and eight in-depth interviews (IDIs) were conducted with HIV-infected 15–25-year-old ART recipients. Transcripts were coded thematically. Participants (<italic>n</italic> = 26) were aged median 18.5 years, 59.1% female and 69.2% virally suppressed <400 cp/ml. Three main themes emerged during FGDs and IDIs: (i) correct knowledge about how to be adherent, benefits, and nonadherence consequences, (ii) social, personal, and medication-related barriers to adherence, and (iii) reminder, concealment, and motivational strategies to optimize adherence. Interventions to improve AYA adherence could focus on practical strategies, including status disclosure and medication concealment.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Shisana, O" uniqKey="Shisana O">O. Shisana</name></author><author><name sortKey="Rehle, T" uniqKey="Rehle T">T. Rehle</name></author><author><name sortKey="Simbayi, L C" uniqKey="Simbayi L">L. C. Simbayi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Nglazi, M D" uniqKey="Nglazi M">M. D. Nglazi</name></author><author><name sortKey="Kranzer, K" uniqKey="Kranzer K">K. Kranzer</name></author><author><name sortKey="Holele, P" uniqKey="Holele P">P. Holele</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chigwedere, P" uniqKey="Chigwedere P">P. Chigwedere</name></author><author><name sortKey="Seage, G R" uniqKey="Seage G">G. R. 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Webber</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mutwa, P R" uniqKey="Mutwa P">P. R. Mutwa</name></author><author><name sortKey="Van Nuil, J I" uniqKey="Van Nuil J">J. I. Van Nuil</name></author><author><name sortKey="Asiimwe Kateera, B" uniqKey="Asiimwe Kateera B">B. Asiimwe-Kateera</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Afrique du Sud</li></country><region><li>Gauteng</li></region><settlement><li>Johannesbourg</li></settlement><orgName><li>Université du Witwatersrand</li></orgName></list><tree><country name="Afrique du Sud"><region name="Gauteng"><name sortKey="Hornschuh, Stefanie" sort="Hornschuh, Stefanie" uniqKey="Hornschuh S" first="Stefanie" last="Hornschuh">Stefanie Hornschuh</name></region><name sortKey="Dietrich, Janan Janine" sort="Dietrich, Janan Janine" uniqKey="Dietrich J" first="Janan Janine" last="Dietrich">Janan Janine Dietrich</name><name sortKey="Laher, Fatima" sort="Laher, Fatima" uniqKey="Laher F" first="Fatima" last="Laher">Fatima Laher</name><name sortKey="Tshabalala, Celokuhle" sort="Tshabalala, Celokuhle" uniqKey="Tshabalala C" first="Celokuhle" last="Tshabalala">Celokuhle Tshabalala</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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