Acute extrapyramidal dysfunction in two HIV-infected children.
Identifieur interne : 003E75 ( Main/Curation ); précédent : 003E74; suivant : 003E76Acute extrapyramidal dysfunction in two HIV-infected children.
Auteurs : Regan Solomons [Afrique du Sud] ; Amy Slogrove ; Johan Schoeman ; Ben Marais ; Gert Van Zyl ; Jean Maritz ; Ronald Van ToornSource :
- Journal of tropical pediatrics [ 1465-3664 ] ; 2011.
Descripteurs français
- KwdFr :
- Affections des ganglions de la base (diagnostic), Affections des ganglions de la base (étiologie), Dyskinésies (étiologie), Enfant, Femelle, Humains, Infections opportunistes liées au SIDA (), Infections opportunistes liées au SIDA (diagnostic), Infections à VIH (), Infections à VIH (diagnostic), Infections à cytomégalovirus (), Infections à cytomégalovirus (diagnostic), Mâle, Nourrisson.
- MESH :
- diagnostic : Affections des ganglions de la base, Infections opportunistes liées au SIDA, Infections à VIH, Infections à cytomégalovirus.
- étiologie : Affections des ganglions de la base, Dyskinésies.
- Enfant, Femelle, Humains, Infections opportunistes liées au SIDA, Infections à VIH, Infections à cytomégalovirus, Mâle, Nourrisson.
English descriptors
- KwdEn :
- AIDS-Related Opportunistic Infections (complications), AIDS-Related Opportunistic Infections (diagnosis), Basal Ganglia Diseases (diagnosis), Basal Ganglia Diseases (etiology), Child, Cytomegalovirus Infections (complications), Cytomegalovirus Infections (diagnosis), Dyskinesias (etiology), Female, HIV Infections (complications), HIV Infections (diagnosis), Humans, Infant, Male.
- MESH :
- complications : AIDS-Related Opportunistic Infections, Cytomegalovirus Infections, HIV Infections.
- diagnosis : AIDS-Related Opportunistic Infections, Basal Ganglia Diseases, Cytomegalovirus Infections, HIV Infections.
- etiology : Basal Ganglia Diseases, Dyskinesias.
- Child, Female, Humans, Infant, Male.
Abstract
Involvement of the basal ganglia is well documented in children with human immunodeficiency virus (HIV) encephalopathy, often with calcification. High concentrations of HIV protein have been detected in affected basal ganglia, although extrapyramidal dysfunction, in contrast to adults, is infrequently encountered in HIV-infected children. We describe the clinical course, magnetic resonance imaging appearance and outcome of two HIV-infected children who presented with acute debilitating extrapyramidal dysfunction. The cases highlight the importance of immune competence, co-existence of opportunistic infections, HIV testing of all children of HIV-infected mothers and magnetic resonance imaging when assessing the severity and anticipating outcomes of movement disorders in HIV-infected children.
DOI: 10.1093/tropej/fmq080
PubMed: 20837555
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<term>Basal Ganglia Diseases (etiology)</term>
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<term>Cytomegalovirus Infections (complications)</term>
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<term>Infections opportunistes liées au SIDA (diagnostic)</term>
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<term>Infections à cytomégalovirus (diagnostic)</term>
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<front><div type="abstract" xml:lang="en">Involvement of the basal ganglia is well documented in children with human immunodeficiency virus (HIV) encephalopathy, often with calcification. High concentrations of HIV protein have been detected in affected basal ganglia, although extrapyramidal dysfunction, in contrast to adults, is infrequently encountered in HIV-infected children. We describe the clinical course, magnetic resonance imaging appearance and outcome of two HIV-infected children who presented with acute debilitating extrapyramidal dysfunction. The cases highlight the importance of immune competence, co-existence of opportunistic infections, HIV testing of all children of HIV-infected mothers and magnetic resonance imaging when assessing the severity and anticipating outcomes of movement disorders in HIV-infected children.</div>
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