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Acute extrapyramidal dysfunction in two HIV-infected children.

Identifieur interne : 003E75 ( Main/Curation ); précédent : 003E74; suivant : 003E76

Acute extrapyramidal dysfunction in two HIV-infected children.

Auteurs : Regan Solomons [Afrique du Sud] ; Amy Slogrove ; Johan Schoeman ; Ben Marais ; Gert Van Zyl ; Jean Maritz ; Ronald Van Toorn

Source :

RBID : pubmed:20837555

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English descriptors

Abstract

Involvement of the basal ganglia is well documented in children with human immunodeficiency virus (HIV) encephalopathy, often with calcification. High concentrations of HIV protein have been detected in affected basal ganglia, although extrapyramidal dysfunction, in contrast to adults, is infrequently encountered in HIV-infected children. We describe the clinical course, magnetic resonance imaging appearance and outcome of two HIV-infected children who presented with acute debilitating extrapyramidal dysfunction. The cases highlight the importance of immune competence, co-existence of opportunistic infections, HIV testing of all children of HIV-infected mothers and magnetic resonance imaging when assessing the severity and anticipating outcomes of movement disorders in HIV-infected children.

DOI: 10.1093/tropej/fmq080
PubMed: 20837555

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pubmed:20837555

Le document en format XML

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<div type="abstract" xml:lang="en">Involvement of the basal ganglia is well documented in children with human immunodeficiency virus (HIV) encephalopathy, often with calcification. High concentrations of HIV protein have been detected in affected basal ganglia, although extrapyramidal dysfunction, in contrast to adults, is infrequently encountered in HIV-infected children. We describe the clinical course, magnetic resonance imaging appearance and outcome of two HIV-infected children who presented with acute debilitating extrapyramidal dysfunction. The cases highlight the importance of immune competence, co-existence of opportunistic infections, HIV testing of all children of HIV-infected mothers and magnetic resonance imaging when assessing the severity and anticipating outcomes of movement disorders in HIV-infected children.</div>
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