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The impact of human immunodeficiency virus (HIV) infection on quality of life in a multiracial South African population

Identifieur interne : 005193 ( Istex/Corpus ); précédent : 005192; suivant : 005194

The impact of human immunodeficiency virus (HIV) infection on quality of life in a multiracial South African population

Auteurs : E. A. O'Keefe ; R. Wood

Source :

RBID : ISTEX:FBF8C06B0708A3FA5B2073424507915F09EDF0B3

English descriptors

Abstract

Abstract: We set out to document quality of life in South African HIV subjects, using the Medical Outcomes Survey (MOS) SF-36 instrument, and to determine whether this was affected by race, gender or clinical stage of disease. A cross-sectional survey of 134 HIV outpatients (42 White, 49 Mixed race, 43 Black) and 114 healthy non-medical hospital personnel (36 White, 37 Mixed race, 42 Black) was carried out at a referral centre for HIV patients in the Western Cape region of South Africa. Scores on eight scales measuring different aspects of quality of life were calculated. Black female controls scored significantly lower on all scales (p<0.05) except physical function. HIV-infected subjects of Mixed race (both genders) reported poorer physical function (p<0.05) but no other scale was affected by race. HIV subjects scored significantly lower than controls on all scales (p<0.01); the majority of the decline in function occurred early in disease by WHO stages 1 and 2. We conclude that HIV-infection impacts early on all aspects of quality of life and that this impact is largely independent of racial origin.

Url:
DOI: 10.1007/BF00434749

Links to Exploration step

ISTEX:FBF8C06B0708A3FA5B2073424507915F09EDF0B3

Le document en format XML

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<GivenName>E.</GivenName>
<GivenName>A.</GivenName>
<FamilyName>O'Keefe</FamilyName>
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<Contact>
<Phone>27 21 402 6911</Phone>
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<OrgName>University of Cape Town</OrgName>
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<Country>South Africa</Country>
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<Para>We set out to document quality of life in South African HIV subjects, using the Medical Outcomes Survey (MOS) SF-36 instrument, and to determine whether this was affected by race, gender or clinical stage of disease. A cross-sectional survey of 134 HIV outpatients (42 White, 49 Mixed race, 43 Black) and 114 healthy non-medical hospital personnel (36 White, 37 Mixed race, 42 Black) was carried out at a referral centre for HIV patients in the Western Cape region of South Africa. Scores on eight scales measuring different aspects of quality of life were calculated. Black female controls scored significantly lower on all scales (
<Emphasis Type="Italic">p</Emphasis>
<0.05) except physical function. HIV-infected subjects of Mixed race (both genders) reported poorer physical function (
<Emphasis Type="Italic">p</Emphasis>
<0.05) but no other scale was affected by race. HIV subjects scored significantly lower than controls on all scales (
<Emphasis Type="Italic">p</Emphasis>
<0.01); the majority of the decline in function occurred early in disease by WHO stages 1 and 2. We conclude that HIV-infection impacts early on all aspects of quality of life and that this impact is largely independent of racial origin.</Para>
</Abstract>
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<Heading>Key words</Heading>
<Keyword>Human immunodeficiency virus (HIV)</Keyword>
<Keyword>Medical Outcomes Survey (MOS) Instrument SF-36</Keyword>
<Keyword>race</Keyword>
<Keyword>quality of life</Keyword>
<Keyword>WHO Clinical disease stage</Keyword>
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<title>The impact of human immunodeficiency virus (HIV) infection on quality of life in a multiracial South African population</title>
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<title>The impact of human immunodeficiency virus (HIV) infection on quality of life in a multiracial South African population</title>
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<abstract lang="en">Abstract: We set out to document quality of life in South African HIV subjects, using the Medical Outcomes Survey (MOS) SF-36 instrument, and to determine whether this was affected by race, gender or clinical stage of disease. A cross-sectional survey of 134 HIV outpatients (42 White, 49 Mixed race, 43 Black) and 114 healthy non-medical hospital personnel (36 White, 37 Mixed race, 42 Black) was carried out at a referral centre for HIV patients in the Western Cape region of South Africa. Scores on eight scales measuring different aspects of quality of life were calculated. Black female controls scored significantly lower on all scales (p<0.05) except physical function. HIV-infected subjects of Mixed race (both genders) reported poorer physical function (p<0.05) but no other scale was affected by race. HIV subjects scored significantly lower than controls on all scales (p<0.01); the majority of the decline in function occurred early in disease by WHO stages 1 and 2. We conclude that HIV-infection impacts early on all aspects of quality of life and that this impact is largely independent of racial origin.</abstract>
<note>Research Papers</note>
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<title>Quality of Life Research</title>
<subTitle>An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation - Official Journal of the International Society of Quality of Life Res</subTitle>
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<title>Qual Life Res</title>
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<topic>Sociology</topic>
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<identifier type="ISSN">0962-9343</identifier>
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