Screening for viral markers in volunteer and replacement blood donors in West Africa
Identifieur interne : 000B55 ( Istex/Corpus ); précédent : 000B54; suivant : 000B56Screening for viral markers in volunteer and replacement blood donors in West Africa
Auteurs : F. Sarkodie ; M. Adarkwa ; Y. Adu-Sarkodie ; D. Candotti ; J. W. Acheampong ; J. P. AllainSource :
- Vox Sanguinis [ 0042-9007 ] ; 2001-04.
English descriptors
- KwdEn :
- Allain, Assay, Blackwell science, Blood donations, Blood donor population, Blood donors, Blood screening, Blood service, Blood services, Blood transfusion, Donation, Donor, East anglia blood centre, Enzyme immunoassay, Equatorial guinea, Grey bars, Hbsag, Hbsag prevalence, Hepatitis, Hepatocellular carcinoma, High level, Human virus, Infection, International society, Komfo anokye teaching hospital, Kumasi, Marker, Median, Murex, Open bars, Overall donor population, Positive samples, Predonation screening, Pregnant women, Present study, Prevalence, Replacement blood donors, Replacement donor population, Replacement donors, Screening, Screening assay, Screening assays, Separate screening assays, Surface antigen, Transfusion, Transfusion medicine, Urban area, Viral, Viral infections, Viral markers, Virus infection, Volunteer blood donors, Volunteer donors, West africa, West african blood donors.
- Teeft :
- Allain, Assay, Blackwell science, Blood donations, Blood donor population, Blood donors, Blood screening, Blood service, Blood services, Blood transfusion, Donation, Donor, East anglia blood centre, Enzyme immunoassay, Equatorial guinea, Grey bars, Hbsag, Hbsag prevalence, Hepatitis, Hepatocellular carcinoma, High level, Human virus, Infection, International society, Komfo anokye teaching hospital, Kumasi, Marker, Median, Murex, Open bars, Overall donor population, Positive samples, Predonation screening, Pregnant women, Present study, Prevalence, Replacement blood donors, Replacement donor population, Replacement donors, Screening, Screening assay, Screening assays, Separate screening assays, Surface antigen, Transfusion, Transfusion medicine, Urban area, Viral, Viral infections, Viral markers, Virus infection, Volunteer blood donors, Volunteer donors, West africa, West african blood donors.
Abstract
West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.
Url:
DOI: 10.1046/j.1423-0410.2001.00023.x
Links to Exploration step
ISTEX:23D73116D46165E68A2BE60E505A8E4D3A8BFB15Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Screening for viral markers in volunteer and replacement blood donors in West Africa</title><author><name sortKey="Sarkodie, F" sort="Sarkodie, F" uniqKey="Sarkodie F" first="F." last="Sarkodie">F. Sarkodie</name><affiliation><mods:affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Adarkwa, M" sort="Adarkwa, M" uniqKey="Adarkwa M" first="M." last="Adarkwa">M. Adarkwa</name><affiliation><mods:affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Adu Arkodie, Y" sort="Adu Arkodie, Y" uniqKey="Adu Arkodie Y" first="Y." last="Adu-Sarkodie">Y. Adu-Sarkodie</name><affiliation><mods:affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Candotti, D" sort="Candotti, D" uniqKey="Candotti D" first="D." last="Candotti">D. Candotti</name><affiliation><mods:affiliation>National Blood Service, East Anglia Blood Centre, Cambridge, UK</mods:affiliation></affiliation></author><author><name sortKey="Acheampong, J W" sort="Acheampong, J W" uniqKey="Acheampong J" first="J. W." last="Acheampong">J. W. Acheampong</name><affiliation><mods:affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Allain, J P" sort="Allain, J P" uniqKey="Allain J" first="J. P." last="Allain">J. P. Allain</name><affiliation><mods:affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: jpa1000@cam.ac.uk</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:23D73116D46165E68A2BE60E505A8E4D3A8BFB15</idno><date when="2001" year="2001">2001</date><idno type="doi">10.1046/j.1423-0410.2001.00023.x</idno><idno type="url">https://api.istex.fr/document/23D73116D46165E68A2BE60E505A8E4D3A8BFB15/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000B55</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000B55</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">Screening for viral markers in volunteer and replacement blood donors in West Africa</title><author><name sortKey="Sarkodie, F" sort="Sarkodie, F" uniqKey="Sarkodie F" first="F." last="Sarkodie">F. Sarkodie</name><affiliation><mods:affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation><affiliation><mods:affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Adarkwa, M" sort="Adarkwa, M" uniqKey="Adarkwa M" first="M." last="Adarkwa">M. Adarkwa</name><affiliation><mods:affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Adu Arkodie, Y" sort="Adu Arkodie, Y" uniqKey="Adu Arkodie Y" first="Y." last="Adu-Sarkodie">Y. Adu-Sarkodie</name><affiliation><mods:affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Candotti, D" sort="Candotti, D" uniqKey="Candotti D" first="D." last="Candotti">D. Candotti</name><affiliation><mods:affiliation>National Blood Service, East Anglia Blood Centre, Cambridge, UK</mods:affiliation></affiliation></author><author><name sortKey="Acheampong, J W" sort="Acheampong, J W" uniqKey="Acheampong J" first="J. W." last="Acheampong">J. W. Acheampong</name><affiliation><mods:affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</mods:affiliation></affiliation></author><author><name sortKey="Allain, J P" sort="Allain, J P" uniqKey="Allain J" first="J. P." last="Allain">J. P. Allain</name><affiliation><mods:affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: jpa1000@cam.ac.uk</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Vox Sanguinis</title><title level="j" type="alt">VOX SANGUINIS</title><idno type="ISSN">0042-9007</idno><idno type="eISSN">1423-0410</idno><imprint><biblScope unit="vol">80</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="142">142</biblScope><biblScope unit="page" to="147">147</biblScope><biblScope unit="page-count">6</biblScope><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2001-04">2001-04</date></imprint><idno type="ISSN">0042-9007</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0042-9007</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Allain</term><term>Assay</term><term>Blackwell science</term><term>Blood donations</term><term>Blood donor population</term><term>Blood donors</term><term>Blood screening</term><term>Blood service</term><term>Blood services</term><term>Blood transfusion</term><term>Donation</term><term>Donor</term><term>East anglia blood centre</term><term>Enzyme immunoassay</term><term>Equatorial guinea</term><term>Grey bars</term><term>Hbsag</term><term>Hbsag prevalence</term><term>Hepatitis</term><term>Hepatocellular carcinoma</term><term>High level</term><term>Human virus</term><term>Infection</term><term>International society</term><term>Komfo anokye teaching hospital</term><term>Kumasi</term><term>Marker</term><term>Median</term><term>Murex</term><term>Open bars</term><term>Overall donor population</term><term>Positive samples</term><term>Predonation screening</term><term>Pregnant women</term><term>Present study</term><term>Prevalence</term><term>Replacement blood donors</term><term>Replacement donor population</term><term>Replacement donors</term><term>Screening</term><term>Screening assay</term><term>Screening assays</term><term>Separate screening assays</term><term>Surface antigen</term><term>Transfusion</term><term>Transfusion medicine</term><term>Urban area</term><term>Viral</term><term>Viral infections</term><term>Viral markers</term><term>Virus infection</term><term>Volunteer blood donors</term><term>Volunteer donors</term><term>West africa</term><term>West african blood donors</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Allain</term><term>Assay</term><term>Blackwell science</term><term>Blood donations</term><term>Blood donor population</term><term>Blood donors</term><term>Blood screening</term><term>Blood service</term><term>Blood services</term><term>Blood transfusion</term><term>Donation</term><term>Donor</term><term>East anglia blood centre</term><term>Enzyme immunoassay</term><term>Equatorial guinea</term><term>Grey bars</term><term>Hbsag</term><term>Hbsag prevalence</term><term>Hepatitis</term><term>Hepatocellular carcinoma</term><term>High level</term><term>Human virus</term><term>Infection</term><term>International society</term><term>Komfo anokye teaching hospital</term><term>Kumasi</term><term>Marker</term><term>Median</term><term>Murex</term><term>Open bars</term><term>Overall donor population</term><term>Positive samples</term><term>Predonation screening</term><term>Pregnant women</term><term>Present study</term><term>Prevalence</term><term>Replacement blood donors</term><term>Replacement donor population</term><term>Replacement donors</term><term>Screening</term><term>Screening assay</term><term>Screening assays</term><term>Separate screening assays</term><term>Surface antigen</term><term>Transfusion</term><term>Transfusion medicine</term><term>Urban area</term><term>Viral</term><term>Viral infections</term><term>Viral markers</term><term>Virus infection</term><term>Volunteer blood donors</term><term>Volunteer donors</term><term>West africa</term><term>West african blood donors</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.</div></front></TEI><istex><corpusName>wiley</corpusName><keywords><teeft><json:string>hbsag</json:string><json:string>blood donors</json:string><json:string>viral</json:string><json:string>assay</json:string><json:string>viral markers</json:string><json:string>kumasi</json:string><json:string>transfusion</json:string><json:string>donor</json:string><json:string>allain</json:string><json:string>murex</json:string><json:string>volunteer donors</json:string><json:string>blackwell science</json:string><json:string>replacement blood donors</json:string><json:string>volunteer blood donors</json:string><json:string>human virus</json:string><json:string>komfo anokye teaching hospital</json:string><json:string>prevalence</json:string><json:string>hepatitis</json:string><json:string>west africa</json:string><json:string>present study</json:string><json:string>replacement donors</json:string><json:string>replacement donor population</json:string><json:string>screening</json:string><json:string>median</json:string><json:string>west african blood donors</json:string><json:string>screening assays</json:string><json:string>surface antigen</json:string><json:string>transfusion medicine</json:string><json:string>open bars</json:string><json:string>hepatocellular carcinoma</json:string><json:string>blood services</json:string><json:string>enzyme immunoassay</json:string><json:string>blood donations</json:string><json:string>blood screening</json:string><json:string>viral infections</json:string><json:string>blood service</json:string><json:string>grey bars</json:string><json:string>overall donor population</json:string><json:string>hbsag prevalence</json:string><json:string>urban area</json:string><json:string>blood transfusion</json:string><json:string>high level</json:string><json:string>blood donor population</json:string><json:string>screening assay</json:string><json:string>positive samples</json:string><json:string>east anglia blood centre</json:string><json:string>separate screening assays</json:string><json:string>international society</json:string><json:string>equatorial guinea</json:string><json:string>predonation screening</json:string><json:string>pregnant women</json:string><json:string>virus infection</json:string><json:string>marker</json:string><json:string>infection</json:string><json:string>donation</json:string></teeft></keywords><author><json:item><name>F. Sarkodie</name><affiliations><json:string>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</json:string><json:string>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</json:string></affiliations></json:item><json:item><name>M. Adarkwa</name><affiliations><json:string>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</json:string></affiliations></json:item><json:item><name>Y. Adu‐Sarkodie</name><affiliations><json:string>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</json:string></affiliations></json:item><json:item><name>D. Candotti</name><affiliations><json:string>National Blood Service, East Anglia Blood Centre, Cambridge, UK</json:string></affiliations></json:item><json:item><name>J. W. Acheampong</name><affiliations><json:string>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</json:string></affiliations></json:item><json:item><name>J. P. Allain</name><affiliations><json:string>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK</json:string><json:string>E-mail: jpa1000@cam.ac.uk</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>blood screening</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>HBV</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>HCV</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>HIV</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>West Africa</value></json:item></subject><articleId><json:string>VOX023</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>article</json:string></originalGenre><qualityIndicators><score>3.872</score><pdfVersion>1.3</pdfVersion><pdfPageSize>595.36 x 782.16 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>136</abstractCharCount><pdfWordCount>3608</pdfWordCount><pdfCharCount>22444</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>22</abstractWordCount></qualityIndicators><title>Screening for viral markers in volunteer and replacement blood donors in West Africa</title><genre><json:string>article</json:string></genre><host><title>Vox Sanguinis</title><language><json:string>unknown</json:string></language><doi><json:string>10.1111/(ISSN)1423-0410</json:string></doi><issn><json:string>0042-9007</json:string></issn><eissn><json:string>1423-0410</json:string></eissn><publisherId><json:string>VOX</json:string></publisherId><volume>80</volume><issue>3</issue><pages><first>142</first><last>147</last><total>6</total></pages><genre><json:string>journal</json:string></genre></host><categories><wos><json:string>science</json:string><json:string>hematology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>cardiovascular system & hematology</json:string></scienceMetrix></categories><publicationDate>2001</publicationDate><copyrightDate>2001</copyrightDate><doi><json:string>10.1046/j.1423-0410.2001.00023.x</json:string></doi><id>23D73116D46165E68A2BE60E505A8E4D3A8BFB15</id><score>1</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/23D73116D46165E68A2BE60E505A8E4D3A8BFB15/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/23D73116D46165E68A2BE60E505A8E4D3A8BFB15/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/23D73116D46165E68A2BE60E505A8E4D3A8BFB15/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main">Screening for viral markers in volunteer and replacement blood donors in West Africa</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2001-04"></date></publicationStmt><notesStmt><note type="content-type" subtype="article" source="article" scheme="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</note><note type="publication-type" subtype="journal" scheme="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</note></notesStmt><sourceDesc><biblStruct type="article"><analytic><title level="a" type="main">Screening for viral markers in volunteer and replacement blood donors in West Africa</title><title level="a" type="short">Screening for viral markers in West African blood donors</title><author xml:id="author-0000"><persName><forename type="first">F.</forename><surname>Sarkodie</surname></persName><affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana<address><country key="GH"></country></address></affiliation><affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana<address><country key="GH"></country></address></affiliation></author><author xml:id="author-0001"><persName><forename type="first">M.</forename><surname>Adarkwa</surname></persName><affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana<address><country key="GH"></country></address></affiliation></author><author xml:id="author-0002"><persName><forename type="first">Y.</forename><surname>Adu‐Sarkodie</surname></persName><affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana<address><country key="GH"></country></address></affiliation></author><author xml:id="author-0003"><persName><forename type="first">D.</forename><surname>Candotti</surname></persName><affiliation>National Blood Service, East Anglia Blood Centre, Cambridge, UK<address><country key="GB"></country></address></affiliation></author><author xml:id="author-0004"><persName><forename type="first">J. W.</forename><surname>Acheampong</surname></persName><affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana<address><country key="GH"></country></address></affiliation></author><author xml:id="author-0005" role="corresp"><persName><forename type="first">J. P.</forename><surname>Allain</surname></persName><affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK<address><country key="GB"></country></address></affiliation><affiliation>: Prof. J. P. Allain, Division of Transfusion Medicine, Department of Haematology, East Anglia Blood Centre, Long Road, Cambridge, CB2 2PT, UK E‐mail:jpa1000@cam.ac.uk</affiliation></author><idno type="istex">23D73116D46165E68A2BE60E505A8E4D3A8BFB15</idno><idno type="ark">ark:/67375/WNG-71PBK6QM-Z</idno><idno type="DOI">10.1046/j.1423-0410.2001.00023.x</idno><idno type="unit">VOX023</idno><idno type="toTypesetVersion">file:VOX.VOX23.pdf</idno></analytic><monogr><title level="j" type="main">Vox Sanguinis</title><title level="j" type="alt">VOX SANGUINIS</title><idno type="pISSN">0042-9007</idno><idno type="eISSN">1423-0410</idno><idno type="book-DOI">10.1111/(ISSN)1423-0410</idno><idno type="book-part-DOI">10.1111/vox.2001.80.issue-3</idno><idno type="product">VOX</idno><idno type="publisherDivision">ST</idno><imprint><biblScope unit="vol">80</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="142">142</biblScope><biblScope unit="page" to="147">147</biblScope><biblScope unit="page-count">6</biblScope><publisher>Blackwell Science Ltd</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2001-04"></date></imprint></monogr></biblStruct></sourceDesc></fileDesc><profileDesc><abstract xml:lang="en" style="main">
Background and Objectives
<p>West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.</p>
Materials and Methods
<p>Replacement and volunteer blood donors were screened using enzyme immunoassays (EIAs) for hepatitis B surface antigen (HBsAg), human immunodeficiency virus antibodies (anti‐HIV), HIV p24 antigen, human T‐cell lymphocytotrophic virus‐I and ‐II antibodies (anti‐HTLV‐I/II) and hepatitis C virus antibodies (anti‐HCV).</p>
Results
<p>HBsAg was present at an equally high frequency (15%) in young volunteer (median age 18 years) and older replacement (median age 33 years) blood donors. In contrast, the prevalence of anti‐HIV and anti‐HCV was significantly higher in replacement blood donors (2·4 and 0·3%, respectively, <hi rend="italic">P</hi> < 0·001). HCV RNA was detected in 74 or 55% of seropositive donors, depending on the confirmatory criteria used. No p24 antigen‐positive/anti‐HIV‐negative donations were found. The prevalence of HTLV‐I/II was generally low (0·5%).</p>
Conclusion
<p>All blood donations should be screened for hepatitis B virus (HBV), HIV and HCV markers.</p></abstract><textClass><keywords xml:lang="en"><term xml:id="k1">blood screening</term><term xml:id="k2">HBV</term><term xml:id="k3">HCV</term><term xml:id="k4">HIV</term><term xml:id="k5">West Africa</term></keywords><keywords rend="tocHeading1"><term>Transfusion‐ Transmitted Disease and it's Prevention</term></keywords></textClass><langUsage><language ident="en"></language></langUsage></profileDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/23D73116D46165E68A2BE60E505A8E4D3A8BFB15/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley, elements deleted: body"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Science Ltd</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1423-0410</doi><issn type="print">0042-9007</issn><issn type="electronic">1423-0410</issn><idGroup><id type="product" value="VOX"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="VOX SANGUINIS">Vox Sanguinis</title></titleGroup></publicationMeta><publicationMeta level="part" position="04003"><doi origin="wiley">10.1111/vox.2001.80.issue-3</doi><numberingGroup><numbering type="journalVolume" number="80">80</numbering><numbering type="journalIssue" number="3">3</numbering></numberingGroup><coverDate startDate="2001-04">April 2001</coverDate></publicationMeta><publicationMeta level="unit" type="article" position="0014200" status="forIssue"><doi origin="wiley">10.1046/j.1423-0410.2001.00023.x</doi><idGroup><id type="unit" value="VOX023"></id></idGroup><countGroup><count type="pageTotal" number="6"></count></countGroup><titleGroup><title type="tocHeading1">Transfusion‐ Transmitted Disease and it's Prevention</title></titleGroup><eventGroup><event type="firstOnline" date="2001-12-21"></event><event type="publishedOnlineFinalForm" date="2001-12-21"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:FullText result:FullText" date="2010-02-27"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-02-10"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-11-04"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="142">142</numbering><numbering type="pageLast" number="147">147</numbering></numberingGroup><correspondenceTo>
: Prof. J. P. Allain, Division of Transfusion Medicine, Department of Haematology, East Anglia Blood Centre, Long Road, Cambridge, CB2 2PT, UK E‐mail:<email>jpa1000@cam.ac.uk</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:VOX.VOX23.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Received: 26 July 2000, revised 16 October 2000, accepted 21 October 2000</unparsedEditorialHistory><countGroup><count type="figureTotal" number="2"></count><count type="tableTotal" number="2"></count><count type="formulaTotal" number="0"></count><count type="referenceTotal" number="23"></count><count type="wordTotal" number="4049"></count><count type="linksPubMed" number="0"></count><count type="linksCrossRef" number="0"></count></countGroup><titleGroup><title type="main">Screening for viral markers in volunteer and replacement blood donors in West Africa</title><title type="shortAuthors">F. Sarkodie <i>et al.</i></title><title type="short">Screening for viral markers in West African blood donors</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1 #a2"><personName><givenNames>F.</givenNames><familyName>Sarkodie</familyName></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>M.</givenNames><familyName>Adarkwa</familyName></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a2"><personName><givenNames>Y.</givenNames><familyName>Adu‐Sarkodie</familyName></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a3"><personName><givenNames>D.</givenNames><familyName>Candotti</familyName></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>J. W.</givenNames><familyName>Acheampong</familyName></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a4" corresponding="yes"><personName><givenNames>J. P.</givenNames><familyName>Allain</familyName></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="GH"><unparsedAffiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</unparsedAffiliation></affiliation><affiliation xml:id="a2" countryCode="GH"><unparsedAffiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</unparsedAffiliation></affiliation><affiliation xml:id="a3" countryCode="GB"><unparsedAffiliation>National Blood Service, East Anglia Blood Centre, Cambridge, UK</unparsedAffiliation></affiliation><affiliation xml:id="a4" countryCode="GB"><unparsedAffiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">blood screening</keyword><keyword xml:id="k2">HBV</keyword><keyword xml:id="k3">HCV</keyword><keyword xml:id="k4">HIV</keyword><keyword xml:id="k5">West Africa</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><section xml:id="abs1-1"><title type="main">Background and Objectives</title><p>West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.</p></section><section xml:id="abs1-2"><title type="main">Materials and Methods</title><p>Replacement and volunteer blood donors were screened using enzyme immunoassays (EIAs) for hepatitis B surface antigen (HBsAg), human immunodeficiency virus antibodies (anti‐HIV), HIV p24 antigen, human T‐cell lymphocytotrophic virus‐I and ‐II antibodies (anti‐HTLV‐I/II) and hepatitis C virus antibodies (anti‐HCV).</p></section><section xml:id="abs1-3"><title type="main">Results</title><p>HBsAg was present at an equally high frequency (15%) in young volunteer (median age 18 years) and older replacement (median age 33 years) blood donors. In contrast, the prevalence of anti‐HIV and anti‐HCV was significantly higher in replacement blood donors (2·4 and 0·3%, respectively, <i>P</i> < 0·001). HCV RNA was detected in 74 or 55% of seropositive donors, depending on the confirmatory criteria used. No p24 antigen‐positive/anti‐HIV‐negative donations were found. The prevalence of HTLV‐I/II was generally low (0·5%).</p></section><section xml:id="abs1-4"><title type="main">Conclusion</title><p>All blood donations should be screened for hepatitis B virus (HBV), HIV and HCV markers.</p></section></abstract></abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Screening for viral markers in volunteer and replacement blood donors in West Africa</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Screening for viral markers in West African blood donors</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Screening for viral markers in volunteer and replacement blood donors in West Africa</title></titleInfo><name type="personal"><namePart type="given">F.</namePart><namePart type="family">Sarkodie</namePart><affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</affiliation><affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.</namePart><namePart type="family">Adarkwa</namePart><affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Y.</namePart><namePart type="family">Adu‐Sarkodie</namePart><affiliation>Department of Microbiology, Komfo Anokye Teaching Hospital, Kumasi, Ghana</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Candotti</namePart><affiliation>National Blood Service, East Anglia Blood Centre, Cambridge, UK</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J. W.</namePart><namePart type="family">Acheampong</namePart><affiliation>Blood Service, Department of Medicine, Komfo Anokye Teaching Hospital, Kumasi, Ghana</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J. P.</namePart><namePart type="family">Allain</namePart><affiliation>Division of Transfusion Medicine, Department of Haematology, University of Cambridge, Cambridge, UK</affiliation><affiliation>E-mail: jpa1000@cam.ac.uk</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article" authority="ISTEX" authorityURI="https://content-type.data.istex.fr" valueURI="https://content-type.data.istex.fr/ark:/67375/XTP-6N5SZHKN-D">article</genre><originInfo><publisher>Blackwell Science Ltd</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2001-04</dateIssued><edition>Received: 26 July 2000, revised 16 October 2000, accepted 21 October 2000</edition><copyrightDate encoding="w3cdtf">2001</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><extent unit="figures">2</extent><extent unit="tables">2</extent><extent unit="formulas">0</extent><extent unit="references">23</extent><extent unit="linksCrossRef">0</extent><extent unit="words">4049</extent></physicalDescription><abstract>West Africa is a highly endemic area for viral infections. The prevalence of five viral markers was determined in Ghanaian blood donors.</abstract><abstract>Replacement and volunteer blood donors were screened using enzyme immunoassays (EIAs) for hepatitis B surface antigen (HBsAg), human immunodeficiency virus antibodies (anti‐HIV), HIV p24 antigen, human T‐cell lymphocytotrophic virus‐I and ‐II antibodies (anti‐HTLV‐I/II) and hepatitis C virus antibodies (anti‐HCV).</abstract><abstract>HBsAg was present at an equally high frequency (15%) in young volunteer (median age 18 years) and older replacement (median age 33 years) blood donors. In contrast, the prevalence of anti‐HIV and anti‐HCV was significantly higher in replacement blood donors (2·4 and 0·3%, respectively, P < 0·001). HCV RNA was detected in 74 or 55% of seropositive donors, depending on the confirmatory criteria used. No p24 antigen‐positive/anti‐HIV‐negative donations were found. The prevalence of HTLV‐I/II was generally low (0·5%).</abstract><abstract>All blood donations should be screened for hepatitis B virus (HBV), HIV and HCV markers.</abstract><subject lang="en"><genre>keywords</genre><topic>blood screening</topic><topic>HBV</topic><topic>HCV</topic><topic>HIV</topic><topic>West Africa</topic></subject><relatedItem type="host"><titleInfo><title>Vox Sanguinis</title></titleInfo><genre type="journal" authority="ISTEX" authorityURI="https://publication-type.data.istex.fr" valueURI="https://publication-type.data.istex.fr/ark:/67375/JMC-0GLKJH51-B">journal</genre><identifier type="ISSN">0042-9007</identifier><identifier type="eISSN">1423-0410</identifier><identifier type="DOI">10.1111/(ISSN)1423-0410</identifier><identifier type="PublisherID">VOX</identifier><part><date>2001</date><detail type="volume"><caption>vol.</caption><number>80</number></detail><detail type="issue"><caption>no.</caption><number>3</number></detail><extent unit="pages"><start>142</start><end>147</end><total>6</total></extent></part></relatedItem><identifier type="istex">23D73116D46165E68A2BE60E505A8E4D3A8BFB15</identifier><identifier type="ark">ark:/67375/WNG-71PBK6QM-Z</identifier><identifier type="DOI">10.1046/j.1423-0410.2001.00023.x</identifier><identifier type="ArticleID">VOX023</identifier><recordInfo><recordContentSource authority="ISTEX" authorityURI="https://loaded-corpus.data.istex.fr" valueURI="https://loaded-corpus.data.istex.fr/ark:/67375/XBH-L0C46X92-X">wiley</recordContentSource><recordOrigin>Blackwell Science Ltd</recordOrigin></recordInfo></mods><json:item><extension>json</extension><original>false</original><mimetype>application/json</mimetype><uri>https://api.istex.fr/document/23D73116D46165E68A2BE60E505A8E4D3A8BFB15/metadata/json</uri></json:item></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/SidaSubSaharaV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000B55 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000B55 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= SidaSubSaharaV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:23D73116D46165E68A2BE60E505A8E4D3A8BFB15
|texte= Screening for viral markers in volunteer and replacement blood donors in West Africa
}}
| This area was generated with Dilib version V0.6.32. |  |