Genetic and phylogenetic analysis of HIV type 1 env subtypes in Ghana, west Africa.
Identifieur interne : 000457 ( PubMed/Corpus ); précédent : 000456; suivant : 000458Genetic and phylogenetic analysis of HIV type 1 env subtypes in Ghana, west Africa.
Auteurs : K. Ishikawa ; W. Janssens ; J. Brandful ; L. Heyndrickx ; Y. Takebe ; W. Ampofo ; T. Sata ; S. Yamazaki ; M. Osei-Kwasi ; N. Yamamoto ; Y. Koyanagi ; G. Van Der Groen ; T. KurataSource :
- AIDS research and human retroviruses [ 0889-2229 ] ; 1996.
English descriptors
- KwdEn :
- Adolescent, Adult, Amino Acid Sequence, Female, Genes, env (genetics), Genetic Heterogeneity, Ghana (epidemiology), HIV Envelope Protein gp120 (genetics), HIV Infections (genetics), HIV-1 (genetics), Humans, Male, Middle Aged, Molecular Sequence Data, Peptide Fragments (genetics), Phylogeny, Sequence Homology, Amino Acid.
- MESH :
- chemical , genetics : HIV Envelope Protein gp120, Peptide Fragments.
- geographic , epidemiology : Ghana.
- genetics : Genes, env, HIV Infections, HIV-1.
- Adolescent, Adult, Amino Acid Sequence, Female, Genetic Heterogeneity, Humans, Male, Middle Aged, Molecular Sequence Data, Phylogeny, Sequence Homology, Amino Acid.
DOI: 10.1089/aid.1996.12.1575
PubMed: 8911585
Links to Exploration step
pubmed:8911585Le document en format XML
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<author><name sortKey="Ishikawa, K" sort="Ishikawa, K" uniqKey="Ishikawa K" first="K" last="Ishikawa">K. Ishikawa</name>
<affiliation><nlm:affiliation>Laboratory of AIDS Pathology, National Institute of Health, Tokyo, Japan.</nlm:affiliation>
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<author><name sortKey="Janssens, W" sort="Janssens, W" uniqKey="Janssens W" first="W" last="Janssens">W. Janssens</name>
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<author><name sortKey="Takebe, Y" sort="Takebe, Y" uniqKey="Takebe Y" first="Y" last="Takebe">Y. Takebe</name>
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<author><name sortKey="Osei Kwasi, M" sort="Osei Kwasi, M" uniqKey="Osei Kwasi M" first="M" last="Osei-Kwasi">M. Osei-Kwasi</name>
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<author><name sortKey="Yamamoto, N" sort="Yamamoto, N" uniqKey="Yamamoto N" first="N" last="Yamamoto">N. Yamamoto</name>
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<author><name sortKey="Koyanagi, Y" sort="Koyanagi, Y" uniqKey="Koyanagi Y" first="Y" last="Koyanagi">Y. Koyanagi</name>
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<author><name sortKey="Osei Kwasi, M" sort="Osei Kwasi, M" uniqKey="Osei Kwasi M" first="M" last="Osei-Kwasi">M. Osei-Kwasi</name>
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<author><name sortKey="Yamamoto, N" sort="Yamamoto, N" uniqKey="Yamamoto N" first="N" last="Yamamoto">N. Yamamoto</name>
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<author><name sortKey="Koyanagi, Y" sort="Koyanagi, Y" uniqKey="Koyanagi Y" first="Y" last="Koyanagi">Y. Koyanagi</name>
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<series><title level="j">AIDS research and human retroviruses</title>
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<term>Adult</term>
<term>Amino Acid Sequence</term>
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<term>Genes, env (genetics)</term>
<term>Genetic Heterogeneity</term>
<term>Ghana (epidemiology)</term>
<term>HIV Envelope Protein gp120 (genetics)</term>
<term>HIV Infections (genetics)</term>
<term>HIV-1 (genetics)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Molecular Sequence Data</term>
<term>Peptide Fragments (genetics)</term>
<term>Phylogeny</term>
<term>Sequence Homology, Amino Acid</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>HIV Envelope Protein gp120</term>
<term>Peptide Fragments</term>
</keywords>
<keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Ghana</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Genes, env</term>
<term>HIV Infections</term>
<term>HIV-1</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Amino Acid Sequence</term>
<term>Female</term>
<term>Genetic Heterogeneity</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Molecular Sequence Data</term>
<term>Phylogeny</term>
<term>Sequence Homology, Amino Acid</term>
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<Title>AIDS research and human retroviruses</Title>
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<ArticleTitle>Genetic and phylogenetic analysis of HIV type 1 env subtypes in Ghana, west Africa.</ArticleTitle>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ishikawa</LastName>
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<Author ValidYN="Y"><LastName>Brandful</LastName>
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<Author ValidYN="Y"><LastName>Yamazaki</LastName>
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<Author ValidYN="Y"><LastName>Osei-Kwasi</LastName>
<ForeName>M</ForeName>
<Initials>M</Initials>
</Author>
<Author ValidYN="Y"><LastName>Yamamoto</LastName>
<ForeName>N</ForeName>
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<Author ValidYN="Y"><LastName>Koyanagi</LastName>
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<NameOfSubstance UI="D015699">HIV Envelope Protein gp120</NameOfSubstance>
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<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C059762">HIV envelope protein gp120 (305-321)</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D010446">Peptide Fragments</NameOfSubstance>
</Chemical>
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<CitationSubset>J</CitationSubset>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000595" MajorTopicYN="N">Amino Acid Sequence</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015752" MajorTopicYN="N">Genes, env</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018740" MajorTopicYN="N">Genetic Heterogeneity</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005869" MajorTopicYN="N" Type="Geographic">Ghana</DescriptorName>
<QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015699" MajorTopicYN="N">HIV Envelope Protein gp120</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015658" MajorTopicYN="N">HIV Infections</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015497" MajorTopicYN="N">HIV-1</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008969" MajorTopicYN="N">Molecular Sequence Data</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010446" MajorTopicYN="N">Peptide Fragments</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010802" MajorTopicYN="N">Phylogeny</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017386" MajorTopicYN="N">Sequence Homology, Amino Acid</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<OtherID Source="PIP">122454</OtherID>
<OtherID Source="POP">00265679</OtherID>
<OtherAbstract Type="PIP" Language="eng"><AbstractText>The authors examined HIV-1 genetic variation among 19 HIV-1-infected people of mean age 34.5 years living in Accra, Akwatia, Kumasi, and Ho, in Ghana. One person was of unknown origin. Blood samples were collected between December 1993 and January 1996. 16 of the HIV-1 specimens clustered with members of subtype A, but the clustering was not supported by 70% or more of the bootstrap tests. Two samples clustered with subtype D strains, supported by 92.5% of the bootstrap trees, and one sample clustered with subtype G strains, supported by 96.2% of the bootstrap trees. For the Ghanaian specimens belonging to subtype A, interhost distances at the nucleotide level averaged 14.9%, of range 7.83-20.9%. The interhost distance between the two subtype D samples was 8.2%. A cocirculation of subtypes A, D, and G was identified in Akwatia.</AbstractText>
</OtherAbstract>
<KeywordList Owner="PIP"><Keyword MajorTopicYN="N">Africa</Keyword>
<Keyword MajorTopicYN="N">Africa South Of The Sahara</Keyword>
<Keyword MajorTopicYN="N">Biology</Keyword>
<Keyword MajorTopicYN="N">Developing Countries</Keyword>
<Keyword MajorTopicYN="N">Diseases</Keyword>
<Keyword MajorTopicYN="N">English Speaking Africa</Keyword>
<Keyword MajorTopicYN="Y">Genetics</Keyword>
<Keyword MajorTopicYN="N">Ghana</Keyword>
<Keyword MajorTopicYN="Y">Hiv</Keyword>
<Keyword MajorTopicYN="Y">Hiv Infections</Keyword>
<Keyword MajorTopicYN="Y">Research Report</Keyword>
<Keyword MajorTopicYN="N">Viral Diseases</Keyword>
<Keyword MajorTopicYN="N">Western Africa</Keyword>
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<GeneralNote Owner="PIP">TJ: AIDS RESEARCH AND HUMAN RETROVIRUSES.</GeneralNote>
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